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Items: 8


Transverse cardiac slicing and optical imaging for analysis of transmural gradients in membrane potential and Ca2+ transients in murine heart.

Wen Q, Gandhi K, Capel RA, Hao G, O'Shea C, Neagu G, Pearcey S, Pavlovic D, Terrar DA, Wu J, Faggian G, Camelliti P, Lei M.

J Physiol. 2018 Sep;596(17):3951-3965. doi: 10.1113/JP276239. Epub 2018 Jul 26.


Load-dependent effects of apelin on murine cardiomyocytes.

Peyronnet R, Bollensdorff C, Capel RA, Rog-Zielinska EA, Woods CE, Charo DN, Lookin O, Fajardo G, Ho M, Quertermous T, Ashley EA, Kohl P.

Prog Biophys Mol Biol. 2017 Nov;130(Pt B):333-343. doi: 10.1016/j.pbiomolbio.2017.09.013. Epub 2017 Sep 18.


High resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with Acidic Stores (lysosomes) in the heart.

Aston D, Capel RA, Ford KL, Christian HC, Mirams GR, Rog-Zielinska EA, Kohl P, Galione A, Burton RA, Terrar DA.

Sci Rep. 2017 Jan 17;7:40620. doi: 10.1038/srep40620.


Mapping cardiac microstructure of rabbit heart in different mechanical states by high resolution diffusion tensor imaging: A proof-of-principle study.

Teh I, Burton RA, McClymont D, Capel RA, Aston D, Kohl P, Schneider JE.

Prog Biophys Mol Biol. 2016 Jul;121(2):85-96. doi: 10.1016/j.pbiomolbio.2016.06.001. Epub 2016 Jun 16.


Two-pore Channels (TPC2s) and Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) at Lysosomal-Sarcoplasmic Reticular Junctions Contribute to Acute and Chronic β-Adrenoceptor Signaling in the Heart.

Capel RA, Bolton EL, Lin WK, Aston D, Wang Y, Liu W, Wang X, Burton RA, Bloor-Young D, Shade KT, Ruas M, Parrington J, Churchill GC, Lei M, Galione A, Terrar DA.

J Biol Chem. 2015 Dec 11;290(50):30087-98. doi: 10.1074/jbc.M115.684076. Epub 2015 Oct 5.


Hydroxychloroquine reduces heart rate by modulating the hyperpolarization-activated current If: Novel electrophysiological insights and therapeutic potential.

Capel RA, Herring N, Kalla M, Yavari A, Mirams GR, Douglas G, Bub G, Channon K, Paterson DJ, Terrar DA, Burton RA.

Heart Rhythm. 2015 Oct;12(10):2186-94. doi: 10.1016/j.hrthm.2015.05.027. Epub 2015 May 27.


The importance of Ca(2+)-dependent mechanisms for the initiation of the heartbeat.

Capel RA, Terrar DA.

Front Physiol. 2015 Mar 25;6:80. doi: 10.3389/fphys.2015.00080. eCollection 2015. Review.


Cytosolic calcium ions exert a major influence on the firing rate and maintenance of pacemaker activity in guinea-pig sinus node.

Capel RA, Terrar DA.

Front Physiol. 2015 Feb 10;6:23. doi: 10.3389/fphys.2015.00023. eCollection 2015.

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