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Pregnancy after cerebral venous thrombosis.

Abbattista M, Capecchi M, Martinelli I.

Thromb Res. 2019 Sep;181 Suppl 1:S15-S18. doi: 10.1016/S0049-3848(19)30360-3.


HDAC2 Regulates Site-Specific Acetylation of MDM2 and Its Ubiquitination Signaling in Tumor Suppression.

Patel N, Wang J, Shiozawa K, Jones KB, Zhang Y, Prokop JW, Davenport GG, Nihira NT, Hao Z, Wong D, Brandsmeier L, Meadows SK, Sampaio AV, Werff RV, Endo M, Capecchi MR, McNagny KM, Mak TW, Nielsen TO, Underhill TM, Myers RM, Kondo T, Su L.

iScience. 2019 Mar 29;13:43-54. doi: 10.1016/j.isci.2019.02.008. Epub 2019 Feb 15.


Correction: Two distinct ontogenies confer heterogeneity to mouse brain microglia (doi: 10.1242/dev.152306).

De S, Van Deren D, Peden E, Hockin M, Boulet A, Titen S, Capecchi MR.

Development. 2019 Feb 7;146(3). pii: dev175901. doi: 10.1242/dev.175901. No abstract available.


Concomitant therapy with direct-acting antivirals and chemoimmunotherapy in HCV-associated diffuse large B-cell lymphoma.

Occhipinti V, Farina L, Viganò M, Capecchi M, Labanca S, Fanetti I, Corradini P, Rumi M.

Dig Liver Dis. 2019 May;51(5):719-723. doi: 10.1016/j.dld.2018.10.019. Epub 2018 Nov 3.


Silencing of retrotransposon-derived imprinted gene RTL1 is the main cause for postimplantational failures in mammalian cloning.

Yu D, Wang J, Zou H, Feng T, Chen L, Li J, Qi X, Li Z, Duan X, Xu C, Zhang L, Long X, Lan J, Chen C, Wang C, Xu X, Ren J, Zhao Y, Hu X, Lian Z, Men H, Pan D, Li N, Capecchi MR, Du X, Zhao Y, Wu S.

Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):E11071-E11080. doi: 10.1073/pnas.1814514115. Epub 2018 Oct 31.


The SS18-SSX Oncoprotein Hijacks KDM2B-PRC1.1 to Drive Synovial Sarcoma.

Banito A, Li X, Laporte AN, Roe JS, Sanchez-Vega F, Huang CH, Dancsok AR, Hatzi K, Chen CC, Tschaharganeh DF, Chandwani R, Tasdemir N, Jones KB, Capecchi MR, Vakoc CR, Schultz N, Ladanyi M, Nielsen TO, Lowe SW.

Cancer Cell. 2018 Aug 13;34(2):346-348. doi: 10.1016/j.ccell.2018.07.006. No abstract available.


Two distinct ontogenies confer heterogeneity to mouse brain microglia.

De S, Van Deren D, Peden E, Hockin M, Boulet A, Titen S, Capecchi MR.

Development. 2018 Jul 4;145(13). pii: dev152306. doi: 10.1242/dev.152306. Erratum in: Development. 2019 Feb 7;146(3):.


Cerebral venous sinus thrombosis.

Capecchi M, Abbattista M, Martinelli I.

J Thromb Haemost. 2018 Oct;16(10):1918-1931. doi: 10.1111/jth.14210. Epub 2018 Jul 11. Review.


Guided Bone Regeneration in the Treatment of a Lateral Periodontal Cyst: 2-Year Clinical and Radiologic Follow-up.

Sivolella S, Perin C, Capecchi M, Buongiorno V, Valente M.

Int J Periodontics Restorative Dent. 2018 September/October;38(5):747–754. doi: 10.11607/prd.2767. Epub 2018 Mar 7.


The SS18-SSX Oncoprotein Hijacks KDM2B-PRC1.1 to Drive Synovial Sarcoma.

Banito A, Li X, Laporte AN, Roe JS, Sanchez-Vega F, Huang CH, Dancsok AR, Hatzi K, Chen CC, Tschaharganeh DF, Chandwani R, Tasdemir N, Jones KB, Capecchi MR, Vakoc CR, Schultz N, Ladanyi M, Nielsen TO, Lowe SW.

Cancer Cell. 2018 Mar 12;33(3):527-541.e8. doi: 10.1016/j.ccell.2018.01.018. Epub 2018 Mar 1. Erratum in: Cancer Cell. 2018 Aug 13;34(2):346-348.


Role of T1 mapping as a complementary tool to T2* for non-invasive cardiac iron overload assessment.

Torlasco C, Cassinerio E, Roghi A, Faini A, Capecchi M, Abdel-Gadir A, Giannattasio C, Parati G, Moon JC, Cappellini MD, Pedrotti P.

PLoS One. 2018 Feb 21;13(2):e0192890. doi: 10.1371/journal.pone.0192890. eCollection 2018.


Paracrine osteoprotegerin and β-catenin stabilization support synovial sarcomagenesis in periosteal cells.

Barrott JJ, Illum BE, Jin H, Hedberg ML, Wang Y, Grossmann A, Haldar M, Capecchi MR, Jones KB.

J Clin Invest. 2018 Jan 2;128(1):207-218. doi: 10.1172/JCI94955. Epub 2017 Nov 20.


Corticostriatal circuit defects in Hoxb8 mutant mice.

Nagarajan N, Jones BW, West PJ, Marc RE, Capecchi MR.

Mol Psychiatry. 2017 Nov 28. doi: 10.1038/mp.2017.251. [Epub ahead of print]


What is behind a relapse of thrombotic thrombocytopenic purpura?

Capecchi M, Artoni A, Cappellini MD, Graziadei G.

Intern Emerg Med. 2018 Aug;13(5):709-712. doi: 10.1007/s11739-017-1764-z. Epub 2017 Nov 2. No abstract available.


ZEB1-repressed microRNAs inhibit autocrine signaling that promotes vascular mimicry of breast cancer cells.

Langer EM, Kendsersky ND, Daniel CJ, Kuziel GM, Pelz C, Murphy KM, Capecchi MR, Sears RC.

Oncogene. 2018 Feb 22;37(8):1005-1019. doi: 10.1038/onc.2017.356. Epub 2017 Oct 30.


Corticostriatal circuit defects in Hoxb8 mutant mice.

Nagarajan N, Jones BW, West PJ, Marc RE, Capecchi MR.

Mol Psychiatry. 2018 Sep;23(9):1868-1877. doi: 10.1038/mp.2017.180. Epub 2017 Sep 26. Erratum in: Mol Psychiatry. 2017 Nov 28;:.


Allogeneic stem cell transplantation and subsequent treatments as a comprehensive strategy for long-term survival of multiple myeloma patients.

Montefusco V, Mussetti A, Rezzonico F, Maura F, Pennisi M, de Philippis C, Capecchi M, Corradini P.

Bone Marrow Transplant. 2017 Dec;52(12):1602-1608. doi: 10.1038/bmt.2017.183. Epub 2017 Sep 11.


The Influential Role of BCL2 Family Members in Synovial Sarcomagenesis.

Barrott JJ, Zhu JF, Smith-Fry K, Susko AM, Nollner D, Burrell LD, Pozner A, Capecchi MR, Yap JT, Cannon-Albright LA, Deng X, Jones KB.

Mol Cancer Res. 2017 Dec;15(12):1733-1740. doi: 10.1158/1541-7786.MCR-17-0315. Epub 2017 Aug 29.


Mouse fitness measures reveal incomplete functional redundancy of Hox paralogous group 1 proteins.

Ruff JS, Saffarini RB, Ramoz LL, Morrison LC, Baker S, Laverty SM, Tvrdik P, Capecchi MR, Potts WK.

PLoS One. 2017 Apr 5;12(4):e0174975. doi: 10.1371/journal.pone.0174975. eCollection 2017.


Deep-brain imaging via epi-fluorescence Computational Cannula Microscopy.

Kim G, Nagarajan N, Pastuzyn E, Jenks K, Capecchi M, Shepherd J, Menon R.

Sci Rep. 2017 Mar 20;7:44791. doi: 10.1038/srep44791.


Derivation of Transgene-Free Rat Induced Pluripotent Stem Cells Approximating the Quality of Embryonic Stem Cells.

Li S, Lan H, Men H, Wu Y, Li N, Capecchi MR, Bryda EC, Wu S.

Stem Cells Transl Med. 2017 Feb;6(2):340-351. doi: 10.5966/sctm.2015-0390. Epub 2016 Sep 13.


piggyBac mediates efficient in vivo CRISPR library screening for tumorigenesis in mice.

Xu C, Qi X, Du X, Zou H, Gao F, Feng T, Lu H, Li S, An X, Zhang L, Wu Y, Liu Y, Li N, Capecchi MR, Wu S.

Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):722-727. doi: 10.1073/pnas.1615735114. Epub 2017 Jan 6.


Non-HCV-related cryoglobulinemic vasculitis and parvovirus-B19 infection.

Lazzerini PE, Cusi MG, Selvi E, Capecchi M, Moscadelli V, Migliacci N, Finizola F, Laghi-Pasini F.

Joint Bone Spine. 2018 Jan;85(1):129-130. doi: 10.1016/j.jbspin.2016.12.013. Epub 2017 Jan 3. No abstract available.


Modeling synovial sarcoma metastasis in the mouse: PI3'-lipid signaling and inflammation.

Barrott JJ, Kafchinski LA, Jin H, Potter JW, Kannan SD, Kennedy R, Mosbruger T, Wang WL, Tsai JW, Araujo DM, Liu T, Capecchi MR, Lazar AJ, Jones KB.

J Exp Med. 2016 Dec 12;213(13):2989-3005. Epub 2016 Nov 9.


Human selenoprotein P and S variant mRNAs with different numbers of SECIS elements and inferences from mutant mice of the roles of multiple SECIS elements.

Wu S, Mariotti M, Santesmasses D, Hill KE, Baclaocos J, Aparicio-Prat E, Li S, Mackrill J, Wu Y, Howard MT, Capecchi M, Guigó R, Burk RF, Atkins JF.

Open Biol. 2016 Nov;6(11). pii: 160241.


Genome-wide piggyBac transposon mediated screening reveals genes related to reprogramming.

Zhang X, Wei X, Wu Y, Wang Y, Tan C, Hu X, Li N, Capecchi MR, Wu S.

Protein Cell. 2017 Feb;8(2):134-139. doi: 10.1007/s13238-016-0332-z. No abstract available.


Efficient generation of selection-gene-free rat knockout models by homologous recombination in ES cells.

Lan H, Li S, Guo Z, Men H, Wu Y, Li N, Bryda EC, Capecchi MR, Wu S.

FEBS Lett. 2016 Oct;590(19):3416-3424. doi: 10.1002/1873-3468.12388. Epub 2016 Sep 18.


The impact of chromosomal translocation locus and fusion oncogene coding sequence in synovial sarcomagenesis.

Jones KB, Barrott JJ, Xie M, Haldar M, Jin H, Zhu JF, Monument MJ, Mosbruger TL, Langer EM, Randall RL, Wilson RK, Cairns BR, Ding L, Capecchi MR.

Oncogene. 2016 Sep 22;35(38):5021-32. doi: 10.1038/onc.2016.38. Epub 2016 Mar 7.


ASPM regulates symmetric stem cell division by tuning Cyclin E ubiquitination.

Capecchi MR, Pozner A.

Nat Commun. 2015 Nov 19;6:8763. doi: 10.1038/ncomms9763.


Type I IFNs Act upon Hematopoietic Progenitors To Protect and Maintain Hematopoiesis during Pneumocystis Lung Infection in Mice.

Prigge JR, Hoyt TR, Dobrinen E, Capecchi MR, Schmidt EE, Meissner N.

J Immunol. 2015 Dec 1;195(11):5347-57. doi: 10.4049/jimmunol.1501553. Epub 2015 Oct 30.


Cardiac Bmi1(+) cells contribute to myocardial renewal in the murine adult heart.

Valiente-Alandi I, Albo-Castellanos C, Herrero D, Arza E, Garcia-Gomez M, Segovia JC, Capecchi M, Bernad A.

Stem Cell Res Ther. 2015 Oct 26;6:205. doi: 10.1186/s13287-015-0196-9.


Hoxc8 initiates an ectopic mammary program by regulating Fgf10 and Tbx3 expression and Wnt/β-catenin signaling.

Carroll LS, Capecchi MR.

Development. 2015 Dec 1;142(23):4056-67. doi: 10.1242/dev.128298. Epub 2015 Oct 12.


Hoxb1 regulates proliferation and differentiation of second heart field progenitors in pharyngeal mesoderm and genetically interacts with Hoxa1 during cardiac outflow tract development.

Roux M, Laforest B, Capecchi M, Bertrand N, Zaffran S.

Dev Biol. 2015 Oct 15;406(2):247-58. doi: 10.1016/j.ydbio.2015.08.015. Epub 2015 Aug 15.


β-catenin stabilization enhances SS18-SSX2-driven synovial sarcomagenesis and blocks the mesenchymal to epithelial transition.

Barrott JJ, Illum BE, Jin H, Zhu JF, Mosbruger T, Monument MJ, Smith-Fry K, Cable MG, Wang Y, Grossmann AH, Capecchi MR, Jones KB.

Oncotarget. 2015 Sep 8;6(26):22758-66.


Intracellular calcium dynamics in cortical microglia responding to focal laser injury in the PC::G5-tdT reporter mouse.

Pozner A, Xu B, Palumbos S, Gee JM, Tvrdik P, Capecchi MR.

Front Mol Neurosci. 2015 May 8;8:12. doi: 10.3389/fnmol.2015.00012. eCollection 2015.


Imaging activity in astrocytes and neurons with genetically encoded calcium indicators following in utero electroporation.

Gee JM, Gibbons MB, Taheri M, Palumbos S, Morris SC, Smeal RM, Flynn KF, Economo MN, Cizek CG, Capecchi MR, Tvrdik P, Wilcox KS, White JA.

Front Mol Neurosci. 2015 Apr 15;8:10. doi: 10.3389/fnmol.2015.00010. eCollection 2015.


Response: Contributions of the Myf5-independent lineage to myogenesis.

Haldar M, Karan G, Watanabe S, Guenther S, Braun T, Capecchi MR.

Dev Cell. 2014 Dec 8;31(5):539-41. doi: 10.1016/j.devcel.2014.11.010.


Modeling alveolar soft part sarcomagenesis in the mouse: a role for lactate in the tumor microenvironment.

Goodwin ML, Jin H, Straessler K, Smith-Fry K, Zhu JF, Monument MJ, Grossmann A, Randall RL, Capecchi MR, Jones KB.

Cancer Cell. 2014 Dec 8;26(6):851-862. doi: 10.1016/j.ccell.2014.10.003. Epub 2014 Nov 26.


The impact of osteoblastic differentiation on osteosarcomagenesis in the mouse.

Quist T, Jin H, Zhu JF, Smith-Fry K, Capecchi MR, Jones KB.

Oncogene. 2015 Aug 6;34(32):4278-84. doi: 10.1038/onc.2014.354. Epub 2014 Oct 27.


Pro-proliferative and inflammatory signaling converge on FoxO1 transcription factor in pulmonary hypertension.

Savai R, Al-Tamari HM, Sedding D, Kojonazarov B, Muecke C, Teske R, Capecchi MR, Weissmann N, Grimminger F, Seeger W, Schermuly RT, Pullamsetti SS.

Nat Med. 2014 Nov;20(11):1289-300. doi: 10.1038/nm.3695. Epub 2014 Oct 26.


Multiple roles for HOXA3 in regulating thymus and parathyroid differentiation and morphogenesis in mouse.

Chojnowski JL, Masuda K, Trau HA, Thomas K, Capecchi M, Manley NR.

Development. 2014 Oct;141(19):3697-708. doi: 10.1242/dev.110833. Epub 2014 Sep 5.


Imaging activity in neurons and glia with a Polr2a-based and cre-dependent GCaMP5G-IRES-tdTomato reporter mouse.

Gee JM, Smith NA, Fernandez FR, Economo MN, Brunert D, Rothermel M, Morris SC, Talbot A, Palumbos S, Ichida JM, Shepherd JD, West PJ, Wachowiak M, Capecchi MR, Wilcox KS, White JA, Tvrdik P.

Neuron. 2014 Sep 3;83(5):1058-72. doi: 10.1016/j.neuron.2014.07.024. Epub 2014 Aug 21.


Lineage of origin in rhabdomyosarcoma informs pharmacological response.

Abraham J, Nuñez-Álvarez Y, Hettmer S, Carrió E, Chen HI, Nishijo K, Huang ET, Prajapati SI, Walker RL, Davis S, Rebeles J, Wiebush H, McCleish AT, Hampton ST, Bjornson CR, Brack AS, Wagers AJ, Rando TA, Capecchi MR, Marini FC, Ehler BR, Zarzabal LA, Goros MW, Michalek JE, Meltzer PS, Langenau DM, LeGallo RD, Mansoor A, Chen Y, Suelves M, Rubin BP, Keller C.

Genes Dev. 2014 Jul 15;28(14):1578-91. doi: 10.1101/gad.238733.114.


Efficient germ-line transmission obtained with transgene-free induced pluripotent stem cells.

Wu S, Wu Y, Zhang X, Capecchi MR.

Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10678-83. doi: 10.1073/pnas.1409933111. Epub 2014 Jul 7.


Fine-tuning of iPSC derivation by an inducible reprogramming system at the protein level.

Sui D, Sun Z, Xu C, Wu Y, Capecchi MR, Wu S, Li N.

Stem Cell Reports. 2014 May 8;2(5):721-33. doi: 10.1016/j.stemcr.2014.03.013. eCollection 2014 May 6.


The c.480C>G polymorphism of hOCT1 influences imatinib clearance in patients affected by chronic myeloid leukemia.

Di Paolo A, Polillo M, Capecchi M, Cervetti G, Baratè C, Angelini S, Guerrini F, Fontanelli G, Arici R, Ciabatti E, Grassi S, Bocci G, Hrelia P, Danesi R, Petrini M, Galimberti S.

Pharmacogenomics J. 2014 Aug;14(4):328-35. doi: 10.1038/tpj.2014.7. Epub 2014 Mar 4.


Sepp1(UF) forms are N-terminal selenoprotein P truncations that have peroxidase activity when coupled with thioredoxin reductase-1.

Kurokawa S, Eriksson S, Rose KL, Wu S, Motley AK, Hill S, Winfrey VP, McDonald WH, Capecchi MR, Atkins JF, Arnér ES, Hill KE, Burk RF.

Free Radic Biol Med. 2014 Apr;69:67-76. doi: 10.1016/j.freeradbiomed.2014.01.010. Epub 2014 Jan 14.


Congenital heart block maternal sera autoantibodies target an extracellular epitope on the α1G T-type calcium channel in human fetal hearts.

Strandberg LS, Cui X, Rath A, Liu J, Silverman ED, Liu X, Siragam V, Ackerley C, Su BB, Yan JY, Capecchi M, Biavati L, Accorroni A, Yuen W, Quattrone F, Lung K, Jaeggi ET, Backx PH, Deber CM, Hamilton RM.

PLoS One. 2013 Sep 9;8(9):e72668. doi: 10.1371/journal.pone.0072668. eCollection 2013.


Nuclear double-fluorescent reporter for in vivo and ex vivo analyses of biological transitions in mouse nuclei.

Prigge JR, Wiley JA, Talago EA, Young EM, Johns LL, Kundert JA, Sonsteng KM, Halford WP, Capecchi MR, Schmidt EE.

Mamm Genome. 2013 Sep 11. [Epub ahead of print]


Targeting the Wnt pathway in synovial sarcoma models.

Barham W, Frump AL, Sherrill TP, Garcia CB, Saito-Diaz K, VanSaun MN, Fingleton B, Gleaves L, Orton D, Capecchi MR, Blackwell TS, Lee E, Yull F, Eid JE.

Cancer Discov. 2013 Nov;3(11):1286-301. doi: 10.1158/2159-8290.CD-13-0138. Epub 2013 Aug 6.

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