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Items: 1 to 50 of 88

1.

Activation of Kv7 Potassium Channels Inhibits Intracellular Ca2+ Increases Triggered By TRPV1-Mediated Pain-Inducing Stimuli in F11 Immortalized Sensory Neurons.

Ambrosino P, Soldovieri MV, Di Zazzo E, Paventi G, Iannotti FA, Mosca I, Miceli F, Franco C, Canzoniero LMT, Taglialatela M.

Int J Mol Sci. 2019 Sep 4;20(18). pii: E4322. doi: 10.3390/ijms20184322.

2.

The activation of Mucolipin TRP channel 1 (TRPML1) protects motor neurons from L-BMAA neurotoxicity by promoting autophagic clearance.

Tedeschi V, Petrozziello T, Sisalli MJ, Boscia F, Canzoniero LMT, Secondo A.

Sci Rep. 2019 Jul 24;9(1):10743. doi: 10.1038/s41598-019-46708-5.

3.

Epileptic Encephalopathy In A Patient With A Novel Variant In The Kv7.2 S2 Transmembrane Segment: Clinical, Genetic, and Functional Features.

Soldovieri MV, Ambrosino P, Mosca I, Miceli F, Franco C, Canzoniero LMT, Kline-Fath B, Cooper EC, Venkatesan C, Taglialatela M.

Int J Mol Sci. 2019 Jul 10;20(14). pii: E3382. doi: 10.3390/ijms20143382.

4.

Characterization of paralogous uncx transcription factor encoding genes in zebrafish.

Nittoli V, Fortunato AE, Fasano G, Coppola U, Gentile A, Maiella S, Langellotto F, Porreca I, De Paolo R, Marino R, Fiengo M, Donizetti A, Aniello F, Kondo T, Ristoratore F, Canzoniero LMT, Duboule D, Wilson SW, Sordino P.

Gene X. 2019 Jun;2:100011. doi: 10.1016/j.gene.2019.100011.

5.

Resveratrol treatment reduces the vulnerability of SH-SY5Y cells and cortical neurons overexpressing SOD1-G93A to Thimerosal toxicity through SIRT1/DREAM/PDYN pathway.

Laudati G, Mascolo L, Guida N, Sirabella R, Pizzorusso V, Bruzzaniti S, Serani A, Di Renzo G, Canzoniero LMT, Formisano L.

Neurotoxicology. 2019 Mar;71:6-15. doi: 10.1016/j.neuro.2018.11.009. Epub 2018 Nov 29.

6.

Ionic Homeostasis Maintenance in ALS: Focus on New Therapeutic Targets.

Sirabella R, Valsecchi V, Anzilotti S, Cuomo O, Vinciguerra A, Cepparulo P, Brancaccio P, Guida N, Blondeau N, Canzoniero LMT, Franco C, Amoroso S, Annunziato L, Pignataro G.

Front Neurosci. 2018 Aug 7;12:510. doi: 10.3389/fnins.2018.00510. eCollection 2018. Review.

7.

The miR206-JunD Circuit Mediates the Neurotoxic Effect of Methylmercury in Cortical Neurons.

Guida N, Valsecchi V, Laudati G, Serani A, Mascolo L, Molinaro P, Montuori P, Di Renzo G, Canzoniero LM, Formisano L.

Toxicol Sci. 2018 Jun 1;163(2):569-578. doi: 10.1093/toxsci/kfy051.

PMID:
29522201
8.

Exenatide exerts cognitive effects by modulating the BDNF-TrkB neurotrophic axis in adult mice.

Bomba M, Granzotto A, Castelli V, Massetti N, Silvestri E, Canzoniero LMT, Cimini A, Sensi SL.

Neurobiol Aging. 2018 Apr;64:33-43. doi: 10.1016/j.neurobiolaging.2017.12.009. Epub 2017 Dec 19.

PMID:
29331730
9.

The neurotoxicant PCB-95 by increasing the neuronal transcriptional repressor REST down-regulates caspase-8 and increases Ripk1, Ripk3 and MLKL expression determining necroptotic neuronal death.

Guida N, Laudati G, Serani A, Mascolo L, Molinaro P, Montuori P, Di Renzo G, Canzoniero LMT, Formisano L.

Biochem Pharmacol. 2017 Oct 15;142:229-241. doi: 10.1016/j.bcp.2017.06.135. Epub 2017 Jul 1.

PMID:
28676433
10.

p38/Sp1/Sp4/HDAC4/BDNF Axis Is a Novel Molecular Pathway of the Neurotoxic Effect of the Methylmercury.

Guida N, Laudati G, Mascolo L, Valsecchi V, Sirabella R, Selleri C, Di Renzo G, Canzoniero LM, Formisano L.

Front Neurosci. 2017 Jan 19;11:8. doi: 10.3389/fnins.2017.00008. eCollection 2017.

11.

MC1568 Inhibits Thimerosal-Induced Apoptotic Cell Death by Preventing HDAC4 Up-Regulation in Neuronal Cells and in Rat Prefrontal Cortex.

Guida N, Laudati G, Mascolo L, Cuomo O, Anzilotti S, Sirabella R, Santopaolo M, Galgani M, Montuori P, Di Renzo G, Canzoniero LM, Formisano L.

Toxicol Sci. 2016 Dec;154(2):227-240. Epub 2016 Sep 22.

PMID:
27660204
12.

Erratum to "Calpains and neuronal damage in the ischemic brain: The swiss knife in synaptic injury" [Progress in Neurobiology 143 (2016) 1-35].

Curcio M, Salazar IL, Mele M, Canzoniero LM, Duarte CB.

Prog Neurobiol. 2016 Dec;147:20. doi: 10.1016/j.pneurobio.2016.08.004. Epub 2016 Sep 5. No abstract available.

PMID:
27609181
13.

Calpains and neuronal damage in the ischemic brain: The swiss knife in synaptic injury.

Curcio M, Salazar IL, Mele M, Canzoniero LM, Duarte CB.

Prog Neurobiol. 2016 Aug;143:1-35. doi: 10.1016/j.pneurobio.2016.06.001. Epub 2016 Jun 6. Review.

PMID:
27283248
14.

Methylmercury upregulates RE-1 silencing transcription factor (REST) in SH-SY5Y cells and mouse cerebellum.

Guida N, Laudati G, Anzilotti S, Sirabella R, Cuomo O, Brancaccio P, Santopaolo M, Galgani M, Montuori P, Di Renzo G, Canzoniero LM, Formisano L.

Neurotoxicology. 2016 Jan;52:89-97. doi: 10.1016/j.neuro.2015.11.007. Epub 2015 Nov 21.

PMID:
26610923
15.

Resveratrol via sirtuin-1 downregulates RE1-silencing transcription factor (REST) expression preventing PCB-95-induced neuronal cell death.

Guida N, Laudati G, Anzilotti S, Secondo A, Montuori P, Di Renzo G, Canzoniero LM, Formisano L.

Toxicol Appl Pharmacol. 2015 Nov 1;288(3):387-98. doi: 10.1016/j.taap.2015.08.010. Epub 2015 Aug 22.

PMID:
26307266
16.

Polychlorinated Biphenyls Induce Mitochondrial Dysfunction in SH-SY5Y Neuroblastoma Cells.

Cocco S, Secondo A, Del Viscovo A, Procaccini C, Formisano L, Franco C, Esposito A, Scorziello A, Matarese G, Di Renzo G, Canzoniero LM.

PLoS One. 2015 Jun 23;10(6):e0129481. doi: 10.1371/journal.pone.0129481. eCollection 2015.

17.

Brain ischemia downregulates the neuroprotective GDNF-Ret signaling by a calpain-dependent mechanism in cultured hippocampal neurons.

Curcio M, Salazar IL, Inácio AR, Duarte EP, Canzoniero LM, Duarte CB.

Cell Death Dis. 2015 Feb 12;6:e1645. doi: 10.1038/cddis.2014.578.

18.

MS-275 inhibits aroclor 1254-induced SH-SY5Y neuronal cell toxicity by preventing the formation of the HDAC3/REST complex on the synapsin-1 promoter.

Formisano L, Guida N, Laudati G, Mascolo L, Di Renzo G, Canzoniero LM.

J Pharmacol Exp Ther. 2015 Feb;352(2):236-43. doi: 10.1124/jpet.114.219345. Epub 2014 Dec 2.

PMID:
25467131
19.

Pyruvate prevents the development of age-dependent cognitive deficits in a mouse model of Alzheimer's disease without reducing amyloid and tau pathology.

Isopi E, Granzotto A, Corona C, Bomba M, Ciavardelli D, Curcio M, Canzoniero LM, Navarra R, Lattanzio R, Piantelli M, Sensi SL.

Neurobiol Dis. 2015 Sep;81:214-24. doi: 10.1016/j.nbd.2014.11.013. Epub 2014 Nov 28.

PMID:
25434488
20.

Extracellular signal-related kinase 2/specificity protein 1/specificity protein 3/repressor element-1 silencing transcription factor pathway is involved in Aroclor 1254-induced toxicity in SH-SY5Y neuronal cells.

Formisano L, Guida N, Laudati G, Boscia F, Esposito A, Secondo A, Di Renzo G, Canzoniero LM.

J Neurosci Res. 2015 Jan;93(1):167-77. doi: 10.1002/jnr.23464. Epub 2014 Aug 5.

PMID:
25093670
21.

Histone deacetylase 4 promotes ubiquitin-dependent proteasomal degradation of Sp3 in SH-SY5Y cells treated with di(2-ethylhexyl)phthalate (DEHP), determining neuronal death.

Guida N, Laudati G, Galgani M, Santopaolo M, Montuori P, Triassi M, Di Renzo G, Canzoniero LM, Formisano L.

Toxicol Appl Pharmacol. 2014 Oct 1;280(1):190-8. doi: 10.1016/j.taap.2014.07.014. Epub 2014 Jul 25.

PMID:
25068794
22.

Critical role of large-conductance calcium- and voltage-activated potassium channels in leptin-induced neuroprotection of N-methyl-d-aspartate-exposed cortical neurons.

Mancini M, Soldovieri MV, Gessner G, Wissuwa B, Barrese V, Boscia F, Secondo A, Miceli F, Franco C, Ambrosino P, Canzoniero LM, Bauer M, Hoshi T, Heinemann SH, Taglialatela M.

Pharmacol Res. 2014 Sep;87:80-6. doi: 10.1016/j.phrs.2014.06.010. Epub 2014 Jun 26.

23.

Role of the ubiquitin-proteasome system in brain ischemia: friend or foe?

Caldeira MV, Salazar IL, Curcio M, Canzoniero LM, Duarte CB.

Prog Neurobiol. 2014 Jan;112:50-69. doi: 10.1016/j.pneurobio.2013.10.003. Epub 2013 Oct 22. Review.

PMID:
24157661
24.

nNOS(+) striatal neurons, a subpopulation spared in Huntington's Disease, possess functional NMDA receptors but fail to generate mitochondrial ROS in response to an excitotoxic challenge.

Canzoniero LM, Granzotto A, Turetsky DM, Choi DW, Dugan LL, Sensi SL.

Front Physiol. 2013 May 16;4:112. doi: 10.3389/fphys.2013.00112. eCollection 2013.

25.

Exenatide promotes cognitive enhancement and positive brain metabolic changes in PS1-KI mice but has no effects in 3xTg-AD animals.

Bomba M, Ciavardelli D, Silvestri E, Canzoniero LM, Lattanzio R, Chiappini P, Piantelli M, Di Ilio C, Consoli A, Sensi SL.

Cell Death Dis. 2013 May 2;4:e612. doi: 10.1038/cddis.2013.139.

26.

Effects of long-term treatment with pioglitazone on cognition and glucose metabolism of PS1-KI, 3xTg-AD, and wild-type mice.

Masciopinto F, Di Pietro N, Corona C, Bomba M, Pipino C, Curcio M, Di Castelnuovo A, Ciavardelli D, Silvestri E, Canzoniero LM, Sekler I, Pandolfi A, Sensi SL.

Cell Death Dis. 2012 Dec 20;3:e448. doi: 10.1038/cddis.2012.189.

27.

NCX1 is a new rest target gene: role in cerebral ischemia.

Formisano L, Guida N, Valsecchi V, Pignataro G, Vinciguerra A, Pannaccione A, Secondo A, Boscia F, Molinaro P, Sisalli MJ, Sirabella R, Casamassa A, Canzoniero LM, Di Renzo G, Annunziato L.

Neurobiol Dis. 2013 Feb;50:76-85. doi: 10.1016/j.nbd.2012.10.010. Epub 2012 Oct 13.

PMID:
23069678
28.

Excitotoxic stimulation downregulates the ubiquitin-proteasome system through activation of NMDA receptors in cultured hippocampal neurons.

Caldeira MV, Curcio M, Leal G, Salazar IL, Mele M, Santos AR, Melo CV, Pereira P, Canzoniero LM, Duarte CB.

Biochim Biophys Acta. 2013 Jan;1832(1):263-74. doi: 10.1016/j.bbadis.2012.10.009. Epub 2012 Oct 13.

29.

Neuroprotection by GDNF in the ischemic brain.

Duarte EP, Curcio M, Canzoniero LM, Duarte CB.

Growth Factors. 2012 Aug;30(4):242-57. doi: 10.3109/08977194.2012.691478. Epub 2012 Jun 7. Review.

PMID:
22670840
30.

Intracellular and plasma membrane-initiated pathways involved in the [Ca2+]i elevations induced by iodothyronines (T3 and T2) in pituitary GH3 cells.

Del Viscovo A, Secondo A, Esposito A, Goglia F, Moreno M, Canzoniero LM.

Am J Physiol Endocrinol Metab. 2012 Jun 1;302(11):E1419-30. doi: 10.1152/ajpendo.00389.2011. Epub 2012 Mar 13.

31.

The repressor element 1-silencing transcription factor is a novel molecular target for the neurotoxic effect of the polychlorinated biphenyl mixture aroclor 1254 in neuroblastoma SH-SY5Y cells.

Formisano L, Guida N, Cocco S, Secondo A, Sirabella R, Ulianich L, Paturzo F, Di Renzo G, Canzoniero LM.

J Pharmacol Exp Ther. 2011 Sep;338(3):997-1003. doi: 10.1124/jpet.111.181289. Epub 2011 Jun 21.

PMID:
21693630
32.

Molecular diagnostics for pharmacogenomic testing of fluoropyrimidine based-therapy: costs, methods and applications.

Di Francia R, Berretta M, Catapano O, Canzoniero LM, Formisano L.

Clin Chem Lab Med. 2011 Jul;49(7):1105-11. doi: 10.1515/CCLM.2011.181. Epub 2011 Apr 20. Review.

PMID:
21504372
33.

Effects of dietary supplementation of carnosine on mitochondrial dysfunction, amyloid pathology, and cognitive deficits in 3xTg-AD mice.

Corona C, Frazzini V, Silvestri E, Lattanzio R, La Sorda R, Piantelli M, Canzoniero LM, Ciavardelli D, Rizzarelli E, Sensi SL.

PLoS One. 2011 Mar 15;6(3):e17971. doi: 10.1371/journal.pone.0017971.

34.

Dietary zinc supplementation of 3xTg-AD mice increases BDNF levels and prevents cognitive deficits as well as mitochondrial dysfunction.

Corona C, Masciopinto F, Silvestri E, Viscovo AD, Lattanzio R, Sorda RL, Ciavardelli D, Goglia F, Piantelli M, Canzoniero LM, Sensi SL.

Cell Death Dis. 2010 Oct 28;1:e91. doi: 10.1038/cddis.2010.73.

35.

Alterations of brain and cerebellar proteomes linked to Aβ and tau pathology in a female triple-transgenic murine model of Alzheimer's disease.

Ciavardelli D, Silvestri E, Del Viscovo A, Bomba M, De Gregorio D, Moreno M, Di Ilio C, Goglia F, Canzoniero LM, Sensi SL.

Cell Death Dis. 2010 Oct 28;1:e90. doi: 10.1038/cddis.2010.68.

36.

Zinc inhibits calcium-mediated and nitric oxide-mediated ion secretion in human enterocytes.

Berni Canani R, Secondo A, Passariello A, Buccigrossi V, Canzoniero LM, Ruotolo S, Puzone C, Porcaro F, Pensa M, Braucci A, Pedata M, Annunziato L, Guarino A.

Eur J Pharmacol. 2010 Jan 25;626(2-3):266-70. doi: 10.1016/j.ejphar.2009.09.042. Epub 2009 Oct 9.

PMID:
19819236
37.

Activation of pre-synaptic M-type K+ channels inhibits [3H]D-aspartate release by reducing Ca2+ entry through P/Q-type voltage-gated Ca2+ channels.

Luisi R, Panza E, Barrese V, Iannotti FA, Viggiano D, Secondo A, Canzoniero LM, Martire M, Annunziato L, Taglialatela M.

J Neurochem. 2009 Apr;109(1):168-81. doi: 10.1111/j.1471-4159.2009.05945.x. Epub 2009 Feb 2.

38.

Decreased presence of perforated synapses in a triple-transgenic mouse model of Alzheimer's disease.

Bertoni-Freddari C, Sensi SL, Giorgetti B, Balietti M, Di Stefano G, Canzoniero LM, Casoli T, Fattoretti P.

Rejuvenation Res. 2008 Apr;11(2):309-13. doi: 10.1089/rej.2008.0660.

PMID:
18328008
39.

Zn(2+) slows down Ca(V)3.3 gating kinetics: implications for thalamocortical activity.

Cataldi M, Lariccia V, Marzaioli V, Cavaccini A, Curia G, Viggiano D, Canzoniero LM, di Renzo G, Avoli M, Annunziato L.

J Neurophysiol. 2007 Oct;98(4):2274-84. Epub 2007 Aug 15.

40.

NO-induced neuroprotection in ischemic preconditioning stimulates mitochondrial Mn-SOD activity and expression via Ras/ERK1/2 pathway.

Scorziello A, Santillo M, Adornetto A, Dell'aversano C, Sirabella R, Damiano S, Canzoniero LM, Renzo GF, Annunziato L.

J Neurochem. 2007 Nov;103(4):1472-80. Epub 2007 Aug 6.

41.

Mild acidosis enhances AMPA receptor-mediated intracellular zinc mobilization in cortical neurons.

Frazzini V, Rapposelli IG, Corona C, Rockabrand E, Canzoniero LM, Sensi SL.

Mol Med. 2007 Jul-Aug;13(7-8):356-61.

42.

The Na+/Ca2+ exchanger isoform 3 (NCX3) but not isoform 2 (NCX2) and 1 (NCX1) singly transfected in BHK cells plays a protective role in a model of in vitro hypoxia.

Secondo A, Staiano IR, Scorziello A, Sirabella R, Boscia F, Adornetto A, Canzoniero LM, Di Renzo G, Annunziato L.

Ann N Y Acad Sci. 2007 Mar;1099:481-5. Review.

PMID:
17446490
43.

BHK cells transfected with NCX3 are more resistant to hypoxia followed by reoxygenation than those transfected with NCX1 and NCX2: Possible relationship with mitochondrial membrane potential.

Secondo A, Staiano RI, Scorziello A, Sirabella R, Boscia F, Adornetto A, Valsecchi V, Molinaro P, Canzoniero LM, Di Renzo G, Annunziato L.

Cell Calcium. 2007 Dec;42(6):521-35. Epub 2007 Mar 6.

PMID:
17343909
44.

Acidosis enhances toxicity induced by kainate and zinc exposure in aged cultured astrocytes.

Sensi SL, Rockabrand E, Canzoniero LM.

Biogerontology. 2006 Oct-Dec;7(5-6):367-74.

PMID:
16964527
45.

Involvement of the nitric oxide/protein kinase G pathway in polychlorinated biphenyl-induced cell death in SH-SY 5Y neuroblastoma cells.

Canzoniero LM, Adornetto A, Secondo A, Magi S, Dell'aversano C, Scorziello A, Amoroso S, Di Renzo G.

J Neurosci Res. 2006 Aug 15;84(3):692-7.

PMID:
16791854
46.

Calcium in Alzheimer's disease pathogenesis: too much, too little or in the wrong place?

Canzoniero LM, Snider BJ.

J Alzheimers Dis. 2005 Nov;8(2):147-54; discussion 209-15. Review.

PMID:
16308483
47.

Neuronal NOS activation during oxygen and glucose deprivation triggers cerebellar granule cell death in the later reoxygenation phase.

Scorziello A, Pellegrini C, Secondo A, Sirabella R, Formisano L, Sibaud L, Amoroso S, Canzoniero LM, Annunziato L, Di Renzo GF.

J Neurosci Res. 2004 Jun 15;76(6):812-21.

PMID:
15160393
48.

Raising intracellular calcium attenuates neuronal apoptosis triggered by staurosporine or oxygen-glucose deprivation in the presence of glutamate receptor blockade.

Canzoniero LM, Babcock DJ, Gottron FJ, Grabb MC, Manzerra P, Snider BJ, Choi DW.

Neurobiol Dis. 2004 Apr;15(3):520-8.

PMID:
15056459
49.

Potassium attenuates zinc-induced death of cultured cortical astrocytes.

Sheline CT, Takata T, Ying H, Canzoniero LM, Yang A, Yu SP, Choi DW.

Glia. 2004 Apr 1;46(1):18-27.

PMID:
14999810
50.

Membrane-permeant chelators can attenuate Zn2+-induced cortical neuronal death.

Canzoniero LM, Manzerra P, Sheline CT, Choi DW.

Neuropharmacology. 2003 Sep;45(3):420-8.

PMID:
12871659

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