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Items: 1 to 50 of 98

1.

Validity of Coronary Artery Disease Consortium Models for Predicting Obstructive Coronary Artery Disease & Cardiovascular Events in Patients with Acute Chest Pain Considered for Coronary Computed Tomographic Angiography.

Teressa G, Zhang M, Lavenburg P, Cantor G, Noack P, Yang J, Goyfman M, Feldmann EJ, Butler J, Poon M.

Am J Cardiol. 2018 Jul 17. pii: S0002-9149(18)31413-9. doi: 10.1016/j.amjcard.2018.07.005. [Epub ahead of print]

PMID:
30119831
2.

Systemic Loss of C-terminal Src Kinase Expression Elicits Spontaneous Suppurative Inflammation in Conditional Knockout Mice.

Berman-Booty LD, Eraslan R, Hanumegowda U, Cantor GH, Bounous DI, Janovitz EB, Jones BK, Buiakova O, Hayward M, Wee S.

Vet Pathol. 2018 Mar;55(2):331-340. doi: 10.1177/0300985817747330. Epub 2018 Jan 16.

PMID:
29338616
3.

Discovery of Highly Potent Liver X Receptor β Agonists.

Kick EK, Busch BB, Martin R, Stevens WC, Bollu V, Xie Y, Boren BC, Nyman MC, Nanao MH, Nguyen L, Plonowski A, Schulman IG, Yan G, Zhang H, Hou X, Valente MN, Narayanan R, Behnia K, Rodrigues AD, Brock B, Smalley J, Cantor GH, Lupisella J, Sleph P, Grimm D, Ostrowski J, Wexler RR, Kirchgessner T, Mohan R.

ACS Med Chem Lett. 2016 Oct 23;7(12):1207-1212. eCollection 2016 Dec 8.

4.

Beneficial and Adverse Effects of an LXR Agonist on Human Lipid and Lipoprotein Metabolism and Circulating Neutrophils.

Kirchgessner TG, Sleph P, Ostrowski J, Lupisella J, Ryan CS, Liu X, Fernando G, Grimm D, Shipkova P, Zhang R, Garcia R, Zhu J, He A, Malone H, Martin R, Behnia K, Wang Z, Barrett YC, Garmise RJ, Yuan L, Zhang J, Gandhi MD, Wastall P, Li T, Du S, Salvador L, Mohan R, Cantor GH, Kick E, Lee J, Frost RJ.

Cell Metab. 2016 Aug 9;24(2):223-33. doi: 10.1016/j.cmet.2016.07.016.

5.

Pharmacological characterization of a novel liver X receptor agonist with partial LXRα activity and a favorable window in nonhuman primates.

Kirchgessner TG, Martin R, Sleph P, Grimm D, Liu X, Lupisella J, Smalley J, Narayanan R, Xie Y, Ostrowski J, Cantor GH, Mohan R, Kick E.

J Pharmacol Exp Ther. 2015 Feb;352(2):305-14. doi: 10.1124/jpet.114.219923. Epub 2014 Dec 2.

6.

Hepatitis C virus NS5A replication complex inhibitors: the discovery of daclatasvir.

Belema M, Nguyen VN, Bachand C, Deon DH, Goodrich JT, James CA, Lavoie R, Lopez OD, Martel A, Romine JL, Ruediger EH, Snyder LB, St Laurent DR, Yang F, Zhu J, Wong HS, Langley DR, Adams SP, Cantor GH, Chimalakonda A, Fura A, Johnson BM, Knipe JO, Parker DD, Santone KS, Fridell RA, Lemm JA, O'Boyle DR 2nd, Colonno RJ, Gao M, Meanwell NA, Hamann LG.

J Med Chem. 2014 Mar 13;57(5):2013-32. doi: 10.1021/jm401836p. Epub 2014 Feb 12.

PMID:
24521299
7.

Discovery of (R)-N-(3-(7-methyl-1H-indazol-5-yl)-1-(4-(1-methylpiperidin-4-yl)-1-oxopropan-2-yl)-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide (BMS-742413): a potent human CGRP antagonist with superior safety profile for the treatment of migraine through intranasal delivery.

Chaturvedula PV, Mercer SE, Pin SS, Thalody G, Xu C, Conway CM, Keavy D, Signor L, Cantor GH, Mathias N, Moench P, Denton R, Macci R, Schartman R, Whiterock V, Davis C, Macor JE, Dubowchik GM.

Bioorg Med Chem Lett. 2013 Jun 1;23(11):3157-61. doi: 10.1016/j.bmcl.2013.04.012. Epub 2013 Apr 12.

PMID:
23632269
8.

Science, providence, and progress at the Great Exhibition.

Cantor G.

Isis. 2012 Sep;103(3):439-59. Review.

PMID:
23286186
9.

Integrated histopathological and urinary metabonomic investigation of the pathogenesis of microcystin-LR toxicosis.

Cantor GH, Beckonert O, Bollard ME, Keun HC, Ebbels TM, Antti H, Wijsman JA, Bible RH, Breau AP, Cockerell GL, Holmes E, Lindon JC, Nicholson JK.

Vet Pathol. 2013 Jan;50(1):159-71. doi: 10.1177/0300985812443839. Epub 2012 May 2.

PMID:
22552484
10.

Fibrinogen deficiency increases liver injury and early growth response-1 (Egr-1) expression in a model of chronic xenobiotic-induced cholestasis.

Luyendyk JP, Kassel KM, Allen K, Guo GL, Li G, Cantor GH, Copple BL.

Am J Pathol. 2011 Mar;178(3):1117-25. doi: 10.1016/j.ajpath.2010.11.064.

11.

Tissue factor contributes to neutrophil CD11b expression in alpha-naphthylisothiocyanate-treated mice.

Luyendyk JP, Flanagan KC, Williams CD, Jaeschke H, Slusser JG, Mackman N, Cantor GH.

Toxicol Appl Pharmacol. 2011 Feb 1;250(3):256-62. doi: 10.1016/j.taap.2010.11.002. Epub 2010 Nov 9.

12.

Urinary metabolites of 2-bromoethanamine identified by stable isotope labelling: evidence for carbamoylation and glutathione conjugation.

Shipkova P, Vassallo JD, Aranibar N, Hnatyshyn S, Zhang H, Clayton TA, Cantor GH, Sanders M, Coen M, Lindon JC, Holmes E, Nicholson JK, Lehman-McKeeman L.

Xenobiotica. 2011 Feb;41(2):144-54. doi: 10.3109/00498254.2010.529179. Epub 2010 Nov 2.

PMID:
21043805
13.

Metabolomics and mechanisms: sometimes the fisher catches a big fish.

Cantor GH.

Toxicol Sci. 2010 Dec;118(2):321-3. doi: 10.1093/toxsci/kfq297. Epub 2010 Sep 23. No abstract available.

PMID:
20864629
14.

Effects of 2-bromoethanamine on TonEBP expression and its possible role in induction of renal papillary necrosis in mice.

Andres-Hernando A, Lanaspa MA, Li N, Cicerchi C, Roncal-Jimenez C, Cantor GH, Sorribas V, Rivard CJ, Berl T.

Toxicol Sci. 2010 Dec;118(2):510-20. doi: 10.1093/toxsci/kfq261. Epub 2010 Sep 7.

15.

Insulin receptor (IR) pathway hyperactivity in IGF-IR null cells and suppression of downstream growth signaling using the dual IGF-IR/IR inhibitor, BMS-754807.

Dinchuk JE, Cao C, Huang F, Reeves KA, Wang J, Myers F, Cantor GH, Zhou X, Attar RM, Gottardis M, Carboni JM.

Endocrinology. 2010 Sep;151(9):4123-32. doi: 10.1210/en.2010-0032. Epub 2010 Jul 7.

PMID:
20610571
16.

BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR.

Carboni JM, Wittman M, Yang Z, Lee F, Greer A, Hurlburt W, Hillerman S, Cao C, Cantor GH, Dell-John J, Chen C, Discenza L, Menard K, Li A, Trainor G, Vyas D, Kramer R, Attar RM, Gottardis MM.

Mol Cancer Ther. 2009 Dec;8(12):3341-9. doi: 10.1158/1535-7163.MCT-09-0499.

17.

Bacterial- and viral-induced inflammation increases sensitivity to acetaminophen hepatotoxicity.

Maddox JF, Amuzie CJ, Li M, Newport SW, Sparkenbaugh E, Cuff CF, Pestka JJ, Cantor GH, Roth RA, Ganey PE.

J Toxicol Environ Health A. 2010;73(1):58-73. doi: 10.1080/15287390903249057.

PMID:
19953420
18.

Mechanistic aspects and novel biomarkers of responder and non-responder phenotypes in galactosamine-induced hepatitis.

Coen M, Want EJ, Clayton TA, Rhode CM, Hong YS, Keun HC, Cantor GH, Metz AL, Robertson DG, Reily MD, Holmes E, Lindon JC, Nicholson JK.

J Proteome Res. 2009 Nov;8(11):5175-87. doi: 10.1021/pr9005266.

19.

Metabonomic investigations into the global biochemical sequelae of exposure to the pancreatic toxin 1-cyano-2-hydroxy-3-butene in the rat.

Bohus E, Rácz A, Noszál B, Coen M, Beckonert O, Keun HC, Ebbels TM, Cantor GH, Wijsman JA, Holmes E, Lindon JC, Nicholson JK.

Magn Reson Chem. 2009 Dec;47 Suppl 1:S26-35. doi: 10.1002/mrc.2485.

PMID:
19639609
20.

NMR-based metabolic profiling identifies biomarkers of liver regeneration following partial hepatectomy in the rat.

Bollard ME, Contel NR, Ebbels TM, Smith L, Beckonert O, Cantor GH, Lehman-McKeeman L, Holmes EC, Lindon JC, Nicholson JK, Keun HC.

J Proteome Res. 2010 Jan;9(1):59-69. doi: 10.1021/pr900200v.

PMID:
19445528
21.

Veterinary pathology and peer review.

Cantor GH, Caswell JL, Crissman JW, Gillette DM, Gunson DE, Hogenesch H, Kiupel M, Mense MG, Miller MA, Rush LJ, Leger JA, Schoeb TR, Sellers RS, Sills RC, Swayne DE, Thomas HC, Ward JM, Alden CL.

Vet Pathol. 2009 Mar;46(2):173-5. doi: 10.1354/vp.46-2-173. No abstract available.

PMID:
19261628
22.

Tissue factor-dependent coagulation contributes to alpha-naphthylisothiocyanate-induced cholestatic liver injury in mice.

Luyendyk JP, Cantor GH, Kirchhofer D, Mackman N, Copple BL, Wang R.

Am J Physiol Gastrointest Liver Physiol. 2009 Apr;296(4):G840-9. doi: 10.1152/ajpgi.90639.2008. Epub 2009 Jan 29.

23.

Editorial: best pathology practices in research using genetically engineered mice.

Bolon B, Brayton C, Cantor GH, Kusewitt DF, Loy JK, Sartin EA, Schoeb TR, Sellers RS, Schuh JC, Ward JM.

Vet Pathol. 2008 Nov;45(6):939-40. doi: 10.1354/vp.45-6-939. No abstract available.

PMID:
18984800
24.

The rise and fall of Emanuel Mendes da Costa: a severe case of the "philosophical dropsy"?

Cantor G.

Engl Hist Rev. 2001;116(467):584-603. No abstract available.

PMID:
18711863
25.

Metabonomics evaluation of urine from rats given acute and chronic doses of acetaminophen using NMR and UPLC/MS.

Sun J, Schnackenberg LK, Holland RD, Schmitt TC, Cantor GH, Dragan YP, Beger RD.

J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Aug 15;871(2):328-40. doi: 10.1016/j.jchromb.2008.04.008. Epub 2008 Apr 12. Erratum in: J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Jan 1;877(1-2):105.

PMID:
18472313
26.

Assessment of necropsy findings in sled dogs that died during Iditarod Trail sled dog races: 23 cases (1994-2006).

Dennis MM, Nelson SN, Cantor GH, Mosier DA, Blake JE, Basaraba RJ.

J Am Vet Med Assoc. 2008 Feb 15;232(4):564-73. doi: 10.2460/javma.232.4.564.

PMID:
18279094
27.

Unique gene expression and hepatocellular injury in the lipopolysaccharide-ranitidine drug idiosyncrasy rat model: comparison with famotidine.

Luyendyk JP, Lehman-McKeeman LD, Nelson DM, Bhaskaran VM, Reilly TP, Car BD, Cantor GH, Maddox JF, Ganey PE, Roth RA.

Toxicol Sci. 2006 Apr;90(2):569-85. Epub 2006 Jan 16.

PMID:
16415329
28.

Coagulation-dependent gene expression and liver injury in rats given lipopolysaccharide with ranitidine but not with famotidine.

Luyendyk JP, Lehman-McKeeman LD, Nelson DM, Bhaskaran VM, Reilly TP, Car BD, Cantor GH, Deng X, Maddox JF, Ganey PE, Roth RA.

J Pharmacol Exp Ther. 2006 May;317(2):635-43. Epub 2006 Jan 9.

29.

Metabonomic evaluation of idiosyncrasy-like liver injury in rats cotreated with ranitidine and lipopolysaccharide.

Maddox JF, Luyendyk JP, Cosma GN, Breau AP, Bible RH Jr, Harrigan GG, Goodacre R, Ganey PE, Cantor GH, Cockerell GL, Roth RA.

Toxicol Appl Pharmacol. 2006 Apr 1;212(1):35-44. Epub 2005 Jul 27.

PMID:
16051291
30.

Summary recommendations for standardization and reporting of metabolic analyses.

Lindon JC, Nicholson JK, Holmes E, Keun HC, Craig A, Pearce JT, Bruce SJ, Hardy N, Sansone SA, Antti H, Jonsson P, Daykin C, Navarange M, Beger RD, Verheij ER, Amberg A, Baunsgaard D, Cantor GH, Lehman-McKeeman L, Earll M, Wold S, Johansson E, Haselden JN, Kramer K, Thomas C, Lindberg J, Schuppe-Koistinen I, Wilson ID, Reily MD, Robertson DG, Senn H, Krotzky A, Kochhar S, Powell J, van der Ouderaa F, Plumb R, Schaefer H, Spraul M; Standard Metabolic Reporting Structures working group.

Nat Biotechnol. 2005 Jul;23(7):833-8. No abstract available.

PMID:
16003371
31.

Comparative metabonomics of differential hydrazine toxicity in the rat and mouse.

Bollard ME, Keun HC, Beckonert O, Ebbels TM, Antti H, Nicholls AW, Shockcor JP, Cantor GH, Stevens G, Lindon JC, Holmes E, Nicholson JK.

Toxicol Appl Pharmacol. 2005 Apr 15;204(2):135-51.

PMID:
15808519
32.

The use of crossreactive monoclonal antibodies to characterize the immune system of the water buffalo (Bubalus bubalis).

Davis WC, Khalid AM, Hamilton MJ, Ahn JS, Park YH, Cantor GH.

J Vet Sci. 2001 Aug;2(2):103-9.

33.
34.

Contemporary issues in toxicology the role of metabonomics in toxicology and its evaluation by the COMET project.

Lindon JC, Nicholson JK, Holmes E, Antti H, Bollard ME, Keun H, Beckonert O, Ebbels TM, Reily MD, Robertson D, Stevens GJ, Luke P, Breau AP, Cantor GH, Bible RH, Niederhauser U, Senn H, Schlotterbeck G, Sidelmann UG, Laursen SM, Tymiak A, Car BD, Lehman-McKeeman L, Colet JM, Loukaci A, Thomas C.

Toxicol Appl Pharmacol. 2003 Mar 15;187(3):137-46.

PMID:
12662897
35.
36.

Surgical treatment of an intramedullary spinal cord hamartoma in a dog.

Sanders SG, Bagley RS, Gavin PR, Konzik RL, Cantor GH.

J Am Vet Med Assoc. 2002 Sep 1;221(5):659-61, 643-4. Erratum in: J Am Vet Med Assoc 2002 Oct 15;221(8):1149.

PMID:
12216904
37.

Fecal polymerase chain reaction with 16S ribosomal RNA primers can detect the presence of gastrointestinal Helicobacter in dogs.

Shinozaki JK, Sellon RK, Cantor GH, Besser TE, Mealey KL, Vaden SL.

J Vet Intern Med. 2002 Jul-Aug;16(4):426-32.

38.

Ivermectin sensitivity in collies is associated with a deletion mutation of the mdr1 gene.

Mealey KL, Bentjen SA, Gay JM, Cantor GH.

Pharmacogenetics. 2001 Nov;11(8):727-33.

PMID:
11692082
40.

Role of the proline-rich motif of bovine leukemia virus transmembrane protein gp30 in viral load and pathogenicity in sheep.

Reichert M, Winnicka A, Willems L, Kettmann R, Cantor GH.

J Virol. 2001 Sep;75(17):8082-9.

41.

Functional cystic thyroid adenoma in a cat.

Hofmeister E, Kippenes H, Mealey KL, Cantor GH, Löhr CV.

J Am Vet Med Assoc. 2001 Jul 15;219(2):190-3.

PMID:
11469573
42.
43.

Protective effects of a live attenuated bovine leukaemia virus vaccine with deletion in the R3 and G4 genes.

Reichert M, Cantor GH, Willems L, Kettmann R.

J Gen Virol. 2000 Apr;81(Pt 4):965-9.

PMID:
10725422
44.

Fighting the wrong battle.

Cantor G.

Nature. 2000 Feb 24;403(6772):831. No abstract available.

PMID:
10706259
45.

Bovine leukemia virus transmembrane protein gp30 physically associates with the down-regulatory phosphatase SHP-1.

Cantor GH, Pritchard SM, Orlik O, Splitter GA, Davis WC, Reeves R.

Cell Immunol. 1999 May 1;193(2):117-24.

PMID:
10222053
46.

Bovine leukemia virus-induced persistent lymphocytosis in cattle does not correlate with increased ex vivo survival of B lymphocytes.

Dequiedt F, Cantor GH, Hamilton VT, Pritchard SM, Davis WC, Kerkhofs P, Burny A, Kettmann R, Willems L.

J Virol. 1999 Feb;73(2):1127-37.

47.

VapA-negative Rhodococcus equi in a dog with necrotizing pyogranulomatous hepatitis, osteomyelitis, and myositis.

Cantor GH, Byrne BA, Hines SA, Richards HM 3rd.

J Vet Diagn Invest. 1998 Jul;10(3):297-300. No abstract available.

PMID:
9683085
48.

Salmonella shedding in racing sled dogs.

Cantor GH, Nelson S Jr, Vanek JA, Evermann JF, Eriks IS, Basaraba RJ, Besser TE.

J Vet Diagn Invest. 1997 Oct;9(4):447-8. No abstract available.

PMID:
9376444
49.

Charles Singer and the early years of the British Society for the History of Science.

Cantor G.

Br J Hist Sci. 1997 Mar;30(104 Pt 1):5-23. No abstract available.

PMID:
11618883
50.

The conduction system in sudden death in Alaskan sled dogs during the Iditarod race and/or during training.

Bharati S, Cantor GH, Leach JB 3rd, Schmidt KE, Blake J.

Pacing Clin Electrophysiol. 1997 Mar;20(3 Pt 1):654-63.

PMID:
9080492

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