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Items: 31


A dual mechanism of activation of the Sonic Hedgehog pathway in anaplastic thyroid cancer: crosstalk with RAS-BRAF-MEK pathway and ligand secretion by tumor stroma.

Parascandolo A, Laukkanen MO, De Rosa N, Ugolini C, Cantisani MC, Cirafici AM, Basolo F, Santoro M, Castellone MD.

Oncotarget. 2017 Dec 17;9(4):4496-4510. doi: 10.18632/oncotarget.23388. eCollection 2018 Jan 12.


A loss-of-function genetic screening identifies novel mediators of thyroid cancer cell viability.

Cantisani MC, Parascandolo A, Perälä M, Allocca C, Fey V, Sahlberg N, Merolla F, Basolo F, Laukkanen MO, Kallioniemi OP, Santoro M, Castellone MD.

Oncotarget. 2016 May 10;7(19):28510-22. doi: 10.18632/oncotarget.8577.


Design and activity of a cyclic mini-β-defensin analog: a novel antimicrobial tool.

Scudiero O, Nigro E, Cantisani M, Colavita I, Leone M, Mercurio FA, Galdiero M, Pessi A, Daniele A, Salvatore F, Galdiero S.

Int J Nanomedicine. 2015 Oct 15;10:6523-39. doi: 10.2147/IJN.S89610. eCollection 2015.


Biocompatible nanoparticles sensing the matrix metallo-proteinase 2 for the on-demand release of anticancer drugs in 3D tumor spheroids.

Cantisani M, Guarnieri D, Biondi M, Belli V, Profeta M, Raiola L, Netti PA.

Colloids Surf B Biointerfaces. 2015 Nov 1;135:707-16. doi: 10.1016/j.colsurfb.2015.08.016. Epub 2015 Aug 21.


Tumor-activated prodrug (TAP)-conjugated nanoparticles with cleavable domains for safe doxorubicin delivery.

Guarnieri D, Biondi M, Yu H, Belli V, Falanga AP, Cantisani M, Galdiero S, Netti PA.

Biotechnol Bioeng. 2015 Mar;112(3):601-11. doi: 10.1002/bit.25454. Epub 2014 Nov 24.


Structural insights into and activity analysis of the antimicrobial peptide myxinidin.

Cantisani M, Finamore E, Mignogna E, Falanga A, Nicoletti GF, Pedone C, Morelli G, Leone M, Galdiero M, Galdiero S.

Antimicrob Agents Chemother. 2014 Sep;58(9):5280-90. doi: 10.1128/AAC.02395-14. Epub 2014 Jun 23.


Conformational modifications of gB from herpes simplex virus type 1 analyzed by synthetic peptides.

Cantisani M, Falanga A, Incoronato N, Russo L, De Simone A, Morelli G, Berisio R, Galdiero M, Galdiero S.

J Med Chem. 2013 Nov 14;56(21):8366-76. doi: 10.1021/jm400771k. Epub 2013 Oct 25.


Peptide-lipid interactions: experiments and applications.

Galdiero S, Falanga A, Cantisani M, Vitiello M, Morelli G, Galdiero M.

Int J Mol Sci. 2013 Sep 12;14(9):18758-89. doi: 10.3390/ijms140918758.


Structure-activity relations of myxinidin, an antibacterial peptide derived from the epidermal mucus of hagfish.

Cantisani M, Leone M, Mignogna E, Kampanaraki K, Falanga A, Morelli G, Galdiero M, Galdiero S.

Antimicrob Agents Chemother. 2013 Nov;57(11):5665-73. doi: 10.1128/AAC.01341-13. Epub 2013 Sep 3.


Peptide inhibitors against herpes simplex virus infections.

Galdiero S, Falanga A, Tarallo R, Russo L, Galdiero E, Cantisani M, Morelli G, Galdiero M.

J Pept Sci. 2013 Mar;19(3):148-58. doi: 10.1002/psc.2489. Epub 2013 Feb 7. Review.


Chimeric beta-defensin analogs, including the novel 3NI analog, display salt-resistant antimicrobial activity and lack toxicity in human epithelial cell lines.

Scudiero O, Galdiero S, Nigro E, Del Vecchio L, Di Noto R, Cantisani M, Colavita I, Galdiero M, Cassiman JJ, Daniele A, Pedone C, Salvatore F.

Antimicrob Agents Chemother. 2013 Apr;57(4):1701-8. doi: 10.1128/AAC.00934-12. Epub 2013 Jan 28.


Microbe-host interactions: structure and role of Gram-negative bacterial porins.

Galdiero S, Falanga A, Cantisani M, Tarallo R, Della Pepa ME, D'Oriano V, Galdiero M.

Curr Protein Pept Sci. 2012 Dec;13(8):843-54. Review. Erratum in: 10.2174/138920371808170602182934.


FOXM1 is a molecular determinant of the mitogenic and invasive phenotype of anaplastic thyroid carcinoma.

Bellelli R, Castellone MD, Garcia-Rostan G, Ugolini C, Nucera C, Sadow PM, Nappi TC, Salerno P, Cantisani MC, Basolo F, Gago TA, Salvatore G, Santoro M.

Endocr Relat Cancer. 2012 Sep 21;19(5):695-710. doi: 10.1530/ERC-12-0031. Print 2012 Oct.


Peptides complementary to the active loop of porin P2 from Haemophilus influenzae modulate its activity.

Cantisani M, Vitiello M, Falanga A, Finamore E, Galdiero M, Galdiero S.

Int J Nanomedicine. 2012;7:2361-71. doi: 10.2147/IJN.S30467. Epub 2012 May 11.


Structure and orientation of the gH625-644 membrane interacting region of herpes simplex virus type 1 in a membrane mimetic system.

Galdiero S, Russo L, Falanga A, Cantisani M, Vitiello M, Fattorusso R, Malgieri G, Galdiero M, Isernia C.

Biochemistry. 2012 Apr 10;51(14):3121-8. doi: 10.1021/bi201589m. Epub 2012 Mar 23.


Biophysical characterization and membrane interaction of the two fusion loops of glycoprotein B from herpes simplex type I virus.

Falanga A, Tarallo R, Vitiello G, Vitiello M, Perillo E, Cantisani M, D'Errico G, Galdiero M, Galdiero S.

PLoS One. 2012;7(2):e32186. doi: 10.1371/journal.pone.0032186. Epub 2012 Feb 23.


Mapping key interactions in the dimerization process of HBHA from Mycobacterium tuberculosis, insights into bacterial agglutination.

Esposito C, Cantisani M, D'Auria G, Falcigno L, Pedone E, Galdiero S, Berisio R.

FEBS Lett. 2012 Mar 23;586(6):659-67. doi: 10.1016/j.febslet.2012.01.047. Epub 2012 Jan 31.


Intracellular delivery: exploiting viral membranotropic peptides.

Galdiero S, Vitiello M, Falanga A, Cantisani M, Incoronato N, Galdiero M.

Curr Drug Metab. 2012 Jan;13(1):93-104. Review.


Silver nanoparticles as potential antiviral agents.

Galdiero S, Falanga A, Vitiello M, Cantisani M, Marra V, Galdiero M.

Molecules. 2011 Oct 24;16(10):8894-918. doi: 10.3390/molecules16108894. Review.


A peptide derived from herpes simplex virus type 1 glycoprotein H: membrane translocation and applications to the delivery of quantum dots.

Falanga A, Vitiello MT, Cantisani M, Tarallo R, Guarnieri D, Mignogna E, Netti P, Pedone C, Galdiero M, Galdiero S.

Nanomedicine. 2011 Dec;7(6):925-34. doi: 10.1016/j.nano.2011.04.009. Epub 2011 May 19.


P2 porin and loop L7 from Haemophilus influenzae modulate expression of IL-6 and adhesion molecules in astrocytes.

Vitiello M, Finamore E, Cantisani M, Bevilacqua P, Incoronato N, Falanga A, Galdiero E, Galdiero M.

Microbiol Immunol. 2011 May;55(5):347-56. doi: 10.1111/j.1348-0421.2011.00318.x.


Viral fusion peptides induce several signal transduction pathway activations that are essential for interleukin-10 and beta-interferon production.

Vitiello M, Finamore E, Falanga A, Raieta K, Cantisani M, Galdiero F, Pedone C, Galdiero M, Galdiero S.

Intervirology. 2010;53(6):381-9. doi: 10.1159/000317287. Epub 2010 Jul 2.


Extracellular superoxide dismutase is a thyroid differentiation marker down-regulated in cancer.

Laatikainen LE, Castellone MD, Hebrant A, Hoste C, Cantisani MC, Laurila JP, Salvatore G, Salerno P, Basolo F, Näsman J, Dumont JE, Santoro M, Laukkanen MO.

Endocr Relat Cancer. 2010 Aug 16;17(3):785-96. doi: 10.1677/ERC-10-0021. Print 2010 Sep.


Novel synthetic, salt-resistant analogs of human beta-defensins 1 and 3 endowed with enhanced antimicrobial activity.

Scudiero O, Galdiero S, Cantisani M, Di Noto R, Vitiello M, Galdiero M, Naclerio G, Cassiman JJ, Pedone C, Castaldo G, Salvatore F.

Antimicrob Agents Chemother. 2010 Jun;54(6):2312-22. doi: 10.1128/AAC.01550-09. Epub 2010 Mar 22.


Proteomic analysis of human U937 cell line activation mediated by Haemophilus influenzae type b P2 porin and its surface-exposed loop 7.

Severino V, Chambery A, Vitiello M, Cantisani M, Galdiero S, Galdiero M, Malorni L, Di Maro A, Parente A.

J Proteome Res. 2010 Feb 5;9(2):1050-62. doi: 10.1021/pr900931n.


Membrane fusion and fission: enveloped viruses.

Falanga A, Cantisani M, Pedone C, Galdiero S.

Protein Pept Lett. 2009;16(7):751-9. Review.


Peptides containing membrane-interacting motifs inhibit herpes simplex virus type 1 infectivity.

Galdiero S, Falanga A, Vitiello M, D'Isanto M, Cantisani M, Kampanaraki A, Benedetti E, Browne H, Galdiero M.

Peptides. 2008 Sep;29(9):1461-71. doi: 10.1016/j.peptides.2008.04.022. Epub 2008 May 17.


Pathophysiological changes of gram-negative bacterial infection can be reproduced by a synthetic peptide mimicking loop L7 sequence of Haemophilus influenzae porin.

Vitiello M, Galdiero S, D'Isanto M, D'Amico M, Di Filippo C, Cantisani M, Galdiero M, Pedone C.

Microbes Infect. 2008 May;10(6):657-63. doi: 10.1016/j.micinf.2008.03.002. Epub 2008 Mar 25.


The identification and characterization of fusogenic domains in herpes virus glycoprotein B molecules.

Galdiero S, Vitiello M, D'Isanto M, Falanga A, Cantisani M, Browne H, Pedone C, Galdiero M.

Chembiochem. 2008 Mar 25;9(5):758-67. doi: 10.1002/cbic.200700457.


Structural requirements for proinflammatory activity of porin P2 Loop 7 from Haemophilus influenzae.

Galdiero S, Vitiello M, Amodeo P, D'Isanto M, Cantisani M, Pedone C, Galdiero M.

Biochemistry. 2006 Apr 11;45(14):4491-501.


RT-PCR comparative study of viral load levels in the HIV positive population in Puerto Rico before and after protease inhibitor regimen implanted.

González N, Rodríguez N, Tripari J, Cantisani M, Morán N, Soto S, Feliciano C, Ramos P, Yamamura Y.

Bol Asoc Med P R. 1998 Jan-Mar;90(1-3):16-20.


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