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Items: 11


An engineered S1P chaperone attenuates hypertension and ischemic injury.

Swendeman SL, Xiong Y, Cantalupo A, Yuan H, Burg N, Hisano Y, Cartier A, Liu CH, Engelbrecht E, Blaho V, Zhang Y, Yanagida K, Galvani S, Obinata H, Salmon JE, Sanchez T, Di Lorenzo A, Hla T.

Sci Signal. 2017 Aug 15;10(492). pii: eaal2722. doi: 10.1126/scisignal.aal2722.


S1PR1 (Sphingosine-1-Phosphate Receptor 1) Signaling Regulates Blood Flow and Pressure.

Cantalupo A, Gargiulo A, Dautaj E, Liu C, Zhang Y, Hla T, Di Lorenzo A.

Hypertension. 2017 Aug;70(2):426-434. doi: 10.1161/HYPERTENSIONAHA.117.09088. Epub 2017 Jun 12.


S1P Signaling and De Novo Biosynthesis in Blood Pressure Homeostasis.

Cantalupo A, Di Lorenzo A.

J Pharmacol Exp Ther. 2016 Aug;358(2):359-70. doi: 10.1124/jpet.116.233205. Epub 2016 Jun 17. Review.


Endothelial Nogo-B regulates sphingolipid biosynthesis to promote pathological cardiac hypertrophy during chronic pressure overload.

Zhang Y, Huang Y, Cantalupo A, Azevedo PS, Siragusa M, Bielawski J, Giordano FJ, Di Lorenzo A.

JCI Insight. 2016 Apr 21;1(5). pii: e85484.


Cystathionine β-synthase-derived hydrogen sulfide is involved in human malignant hyperthermia.

Vellecco V, Mancini A, Ianaro A, Calderone V, Attanasio C, Cantalupo A, Andria B, Savoia G, Panza E, Di Martino A, Cirino G, Bucci M.

Clin Sci (Lond). 2016 Jan;130(1):35-44. doi: 10.1042/CS20150521. Epub 2015 Oct 12.


Nogo-B regulates endothelial sphingolipid homeostasis to control vascular function and blood pressure.

Cantalupo A, Zhang Y, Kothiya M, Galvani S, Obinata H, Bucci M, Giordano FJ, Jiang XC, Hla T, Di Lorenzo A.

Nat Med. 2015 Sep;21(9):1028-1037. doi: 10.1038/nm.3934. Epub 2015 Aug 24.


Hydrogen sulfide accounts for the peripheral vascular effects of zofenopril independently of ACE inhibition.

Bucci M, Vellecco V, Cantalupo A, Brancaleone V, Zhou Z, Evangelista S, Calderone V, Papapetropoulos A, Cirino G.

Cardiovasc Res. 2014 Apr 1;102(1):138-47. doi: 10.1093/cvr/cvu026. Epub 2014 Feb 5.


Hypoxia-inducible factor-1α in vascular smooth muscle regulates blood pressure homeostasis through a peroxisome proliferator-activated receptor-γ-angiotensin II receptor type 1 axis.

Huang Y, Di Lorenzo A, Jiang W, Cantalupo A, Sessa WC, Giordano FJ.

Hypertension. 2013 Sep;62(3):634-40. doi: 10.1161/HYPERTENSIONAHA.111.00160. Epub 2013 Aug 5.


Perthamide C inhibits eNOS and iNOS expression and has immunomodulating activity in vivo.

Bucci M, Cantalupo A, Vellecco V, Panza E, Monti MC, Zampella A, Ianaro A, Cirino G.

PLoS One. 2013;8(3):e57801. doi: 10.1371/journal.pone.0057801. Epub 2013 Mar 12. Retraction in: PLoS One. 2019 Aug 30;14(8):e0222175.


CL316,243, a selective β3-adrenoceptor agonist, activates protein translation through mTOR/p70S6K signaling pathway in rat skeletal muscle cells.

Miniaci MC, Bucci M, Santamaria R, Irace C, Cantalupo A, Cirino G, Scotto P.

Pflugers Arch. 2013 Apr;465(4):509-16. doi: 10.1007/s00424-012-1213-9. Epub 2013 Jan 19.


cGMP-dependent protein kinase contributes to hydrogen sulfide-stimulated vasorelaxation.

Bucci M, Papapetropoulos A, Vellecco V, Zhou Z, Zaid A, Giannogonas P, Cantalupo A, Dhayade S, Karalis KP, Wang R, Feil R, Cirino G.

PLoS One. 2012;7(12):e53319. doi: 10.1371/journal.pone.0053319. Epub 2012 Dec 28.

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