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The Sleeping Cerebellum. Canto CB et al. Trends Neurosci. (2017)

The molecular targets of resveratrol. Kulkarni SS et al. Biochim Biophys Acta. (2015)

Mfn2 is critical for brown adipose tissue thermogenic function. Boutant M et al. EMBO J. (2017)

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Items: 1 to 50 of 127


The natural bioactive quinic acid activates Ca2+ -dependent mitochondrial function and promotes insulin secretion from pancreatic β-cells.

Heikkilä E, Hermant A, Thevenet J, Bermont F, Santo-Domingo J, Dioum EH, Canto C, Barron D, Wiederkehr A, De Marchi U.

Br J Pharmacol. 2019 Jun 5. doi: 10.1111/bph.14757. [Epub ahead of print]


Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease.

Hernández-Alvarez MI, Sebastián D, Vives S, Ivanova S, Bartoccioni P, Kakimoto P, Plana N, Veiga SR, Hernández V, Vasconcelos N, Peddinti G, Adrover A, Jové M, Pamplona R, Gordaliza-Alaguero I, Calvo E, Cabré N, Castro R, Kuzmanic A, Boutant M, Sala D, Hyotylainen T, Orešič M, Fort J, Errasti-Murugarren E, Rodrígues CMP, Orozco M, Joven J, Cantó C, Palacin M, Fernández-Veledo S, Vendrell J, Zorzano A.

Cell. 2019 May 2;177(4):881-895.e17. doi: 10.1016/j.cell.2019.04.010.


The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance.

Vannini N, Campos V, Girotra M, Trachsel V, Rojas-Sutterlin S, Tratwal J, Ragusa S, Stefanidis E, Ryu D, Rainer PY, Nikitin G, Giger S, Li TY, Semilietof A, Oggier A, Yersin Y, Tauzin L, Pirinen E, Cheng WC, Ratajczak J, Canto C, Ehrbar M, Sizzano F, Petrova TV, Vanhecke D, Zhang L, Romero P, Nahimana A, Cherix S, Duchosal MA, Ho PC, Deplancke B, Coukos G, Auwerx J, Lutolf MP, Naveiras O.

Cell Stem Cell. 2019 Mar 7;24(3):405-418.e7. doi: 10.1016/j.stem.2019.02.012.


BK virus salivary shedding and viremia in renal transplant recipients.

Sarmento DJS, Palmieri M, Galvão GS, Tozetto-Mendoza TR, Canto CMD, Pierrotti LC, David-Neto E, Agena F, Gallottini M, Pannuti CS, Fink MCD, Braz-Silva PH.

J Appl Oral Sci. 2019 Jan 14;27:e20180435. doi: 10.1590/1678-7757-2018-0435.


Potential effect of Zika virus infection on human male fertility?

Avelino-Silva VI, Alvarenga C, Abreu C, Tozetto-Mendoza TR, Canto CLMD, Manuli ER, Mendes-Correa MC, Sabino EC, Figueiredo WM, Segurado AC, Mayaud P.

Rev Inst Med Trop Sao Paulo. 2018 Oct 25;60:e64. doi: 10.1590/S1678-9946201860064.


Circadian Rhythms and Mitochondria: Connecting the Dots.

Sardon Puig L, Valera-Alberni M, Cantó C, Pillon NJ.

Front Genet. 2018 Oct 8;9:452. doi: 10.3389/fgene.2018.00452. eCollection 2018.


Intrinsic excitement in cerebellar nuclei neurons during learning.

Canto CB, Broersen R, De Zeeuw CI.

Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):9824-9826. doi: 10.1073/pnas.1813866115. Epub 2018 Sep 14. No abstract available.


Distinct patterns of skeletal muscle mitochondria fusion, fission and mitophagy upon duration of exercise training.

Arribat Y, Broskey NT, Greggio C, Boutant M, Conde Alonso S, Kulkarni SS, Lagarrigue S, Carnero EA, Besson C, Cantó C, Amati F.

Acta Physiol (Oxf). 2019 Feb;225(2):e13179. doi: 10.1111/apha.13179. Epub 2018 Sep 14.


Mitochondrial Dynamics: Shaping Metabolic Adaptation.

Cantó C.

Int Rev Cell Mol Biol. 2018;340:129-167. doi: 10.1016/bs.ircmb.2018.05.004. Epub 2018 Jun 22. Review.


Medium chain triglyceride diet reduces anxiety-like behaviors and enhances social competitiveness in rats.

Hollis F, Mitchell ES, Canto C, Wang D, Sandi C.

Neuropharmacology. 2018 Aug;138:245-256. doi: 10.1016/j.neuropharm.2018.06.017. Epub 2018 Jun 20.


Flared Roots Reinforced With Bulk-fill Flowable Composite - Case Report.

Braz R, Mergulhão VA, Oliveira LR, Alves MS, Canto CA.

Oper Dent. 2018 May/Jun;43(3):225-231. doi: 10.2341/16-221-T.


Morphological and genetic characterisation of the root system architecture of selected barley recombinant chromosome substitution lines using an integrated phenotyping approach.

Canto CF, Kalogiros DI, Ptashnyk M, George TS, Waugh R, Bengough AG, Russell J, Dupuy LX.

J Theor Biol. 2018 Jun 14;447:84-97. doi: 10.1016/j.jtbi.2018.03.020. Epub 2018 Mar 17.


Psychotic symptoms and quality of life: A mediation analysis of daily-life coping.

López-Navarro E, Del Canto C, Mayol A, Fernández-Alonso O, Munar E.

Psychiatry Res. 2018 Apr;262:505-509. doi: 10.1016/j.psychres.2017.09.034. Epub 2017 Sep 12.


LINE-1 hypermethylation in white blood cell DNA is associated with high-grade cervical intraepithelial neoplasia.

Barchitta M, Quattrocchi A, Maugeri A, Canto C, La Rosa N, Cantarella MA, Spampinato G, Scalisi A, Agodi A.

BMC Cancer. 2017 Aug 30;17(1):601. doi: 10.1186/s12885-017-3582-0.


Circadian and Feeding Rhythms Orchestrate the Diurnal Liver Acetylome.

Mauvoisin D, Atger F, Dayon L, Núñez Galindo A, Wang J, Martin E, Da Silva L, Montoliu I, Collino S, Martin FP, Ratajczak J, Cantó C, Kussmann M, Naef F, Gachon F.

Cell Rep. 2017 Aug 15;20(7):1729-1743. doi: 10.1016/j.celrep.2017.07.065.


Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells.

Fletcher RS, Ratajczak J, Doig CL, Oakey LA, Callingham R, Da Silva Xavier G, Garten A, Elhassan YS, Redpath P, Migaud ME, Philp A, Brenner C, Canto C, Lavery GG.

Mol Metab. 2017 May 29;6(8):819-832. doi: 10.1016/j.molmet.2017.05.011. eCollection 2017 Aug.


Diazepam actions in the VTA enhance social dominance and mitochondrial function in the nucleus accumbens by activation of dopamine D1 receptors.

van der Kooij MA, Hollis F, Lozano L, Zalachoras I, Abad S, Zanoletti O, Grosse J, Guillot de Suduiraut I, Canto C, Sandi C.

Mol Psychiatry. 2018 Mar;23(3):569-578. doi: 10.1038/mp.2017.135. Epub 2017 Jul 20.


The Sleeping Cerebellum.

Canto CB, Onuki Y, Bruinsma B, van der Werf YD, De Zeeuw CI.

Trends Neurosci. 2017 May;40(5):309-323. doi: 10.1016/j.tins.2017.03.001. Epub 2017 Apr 18. Review.


Mfn2 is critical for brown adipose tissue thermogenic function.

Boutant M, Kulkarni SS, Joffraud M, Ratajczak J, Valera-Alberni M, Combe R, Zorzano A, Cantó C.

EMBO J. 2017 Jun 1;36(11):1543-1558. doi: 10.15252/embj.201694914. Epub 2017 Mar 27.


The heat shock factor HSF1 juggles protein quality control and metabolic regulation.

Cantó C.

J Cell Biol. 2017 Mar 6;216(3):551-553. doi: 10.1083/jcb.201701093. Epub 2017 Feb 9.


Motor Learning Requires Purkinje Cell Synaptic Potentiation through Activation of AMPA-Receptor Subunit GluA3.

Gutierrez-Castellanos N, Da Silva-Matos CM, Zhou K, Canto CB, Renner MC, Koene LMC, Ozyildirim O, Sprengel R, Kessels HW, De Zeeuw CI.

Neuron. 2017 Jan 18;93(2):409-424. doi: 10.1016/j.neuron.2016.11.046.


Coordinated activation of mitochondrial respiration and exocytosis mediated by PKC signaling in pancreatic β cells.

Santo-Domingo J, Chareyron I, Dayon L, Núñez Galindo A, Cominetti O, Pilar Giner Giménez M, De Marchi U, Canto C, Kussmann M, Wiederkehr A.

FASEB J. 2017 Mar;31(3):1028-1045. doi: 10.1096/fj.201600837R. Epub 2016 Dec 7.


Enhanced Respiratory Chain Supercomplex Formation in Response to Exercise in Human Skeletal Muscle.

Greggio C, Jha P, Kulkarni SS, Lagarrigue S, Broskey NT, Boutant M, Wang X, Conde Alonso S, Ofori E, Auwerx J, Cantó C, Amati F.

Cell Metab. 2017 Feb 7;25(2):301-311. doi: 10.1016/j.cmet.2016.11.004. Epub 2016 Dec 1.


Whole-Cell Properties of Cerebellar Nuclei Neurons In Vivo.

Canto CB, Witter L, De Zeeuw CI.

PLoS One. 2016 Nov 16;11(11):e0165887. doi: 10.1371/journal.pone.0165887. eCollection 2016.


NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation.

Ryu D, Zhang H, Ropelle ER, Sorrentino V, Mázala DA, Mouchiroud L, Marshall PL, Campbell MD, Ali AS, Knowels GM, Bellemin S, Iyer SR, Wang X, Gariani K, Sauve AA, Cantó C, Conley KE, Walter L, Lovering RM, Chin ER, Jasmin BJ, Marcinek DJ, Menzies KJ, Auwerx J.

Sci Transl Med. 2016 Oct 19;8(361):361ra139.


NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells.

Ratajczak J, Joffraud M, Trammell SA, Ras R, Canela N, Boutant M, Kulkarni SS, Rodrigues M, Redpath P, Migaud ME, Auwerx J, Yanes O, Brenner C, Cantó C.

Nat Commun. 2016 Oct 11;7:13103. doi: 10.1038/ncomms13103.


Mfn1 Deficiency in the Liver Protects Against Diet-Induced Insulin Resistance and Enhances the Hypoglycemic Effect of Metformin.

Kulkarni SS, Joffraud M, Boutant M, Ratajczak J, Gao AW, Maclachlan C, Hernandez-Alvarez MI, Raymond F, Metairon S, Descombes P, Houtkooper RH, Zorzano A, Cantó C.

Diabetes. 2016 Dec;65(12):3552-3560. Epub 2016 Sep 9.


SIRT1 Gain of Function Does Not Mimic or Enhance the Adaptations to Intermittent Fasting.

Boutant M, Kulkarni SS, Joffraud M, Raymond F, Métairon S, Descombes P, Cantó C.

Cell Rep. 2016 Mar 8;14(9):2068-2075. doi: 10.1016/j.celrep.2016.02.007. Epub 2016 Feb 25.


SIRT1: A novel guardian of brown fat against metabolic damage.

Boutant M, Cantó C.

Obesity (Silver Spring). 2016 Mar;24(3):554. doi: 10.1002/oby.21432. No abstract available.


Mitochondrial Post-translational Modifications and Metabolic Control: Sirtuins and Beyond.

Kulkarni SS, Cantó C.

Curr Diabetes Rev. 2017;13(4):338-351. doi: 10.2174/1573399812666160217122413. Review.


Mitochondrial function in the brain links anxiety with social subordination.

Hollis F, van der Kooij MA, Zanoletti O, Lozano L, Cantó C, Sandi C.

Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):15486-91. doi: 10.1073/pnas.1512653112. Epub 2015 Nov 30.


[Which genetic testing in renal disease].

Granata M, Canto C, Mazzarino MC, Fatuzzo P, Granata A.

G Ital Nefrol. 2015 Sep-Oct;32(5). pii: gin/32.5.3. Review. Italian.


Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice.

Gariani K, Menzies KJ, Ryu D, Wegner CJ, Wang X, Ropelle ER, Moullan N, Zhang H, Perino A, Lemos V, Kim B, Park YK, Piersigilli A, Pham TX, Yang Y, Ku CS, Koo SI, Fomitchova A, Cantó C, Schoonjans K, Sauve AA, Lee JY, Auwerx J.

Hepatology. 2016 Apr;63(4):1190-204. doi: 10.1002/hep.28245. Epub 2015 Dec 16.


Dietary restriction and Sirtuin 1 in metabolic health: connections and divergences.

Cantó C.

Proc Nutr Soc. 2016 Feb;75(1):30-37. Epub 2015 Sep 7.


Mindfulness improves psychological quality of life in community-based patients with severe mental health problems: A pilot randomized clinical trial.

López-Navarro E, Del Canto C, Belber M, Mayol A, Fernández-Alonso O, Lluis J, Munar E, Chadwick P.

Schizophr Res. 2015 Oct;168(1-2):530-6. doi: 10.1016/j.schres.2015.08.016. Epub 2015 Aug 20.


Low fruit consumption and folate deficiency are associated with LINE-1 hypomethylation in women of a cancer-free population.

Agodi A, Barchitta M, Quattrocchi A, Maugeri A, Canto C, Marchese AE, Vinciguerra M.

Genes Nutr. 2015 Sep;10(5):480. doi: 10.1007/s12263-015-0480-4. Epub 2015 Jul 17.


NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus.

Cantó C, Menzies KJ, Auwerx J.

Cell Metab. 2015 Jul 7;22(1):31-53. doi: 10.1016/j.cmet.2015.05.023. Epub 2015 Jun 25. Review.


High-Resolution Respirometry for Mitochondrial Characterization of Ex Vivo Mouse Tissues.

Cantó C, Garcia-Roves PM.

Curr Protoc Mouse Biol. 2015 Jun 1;5(2):135-153. doi: 10.1002/9780470942390.mo140061.


The effect of C content on the mechanical properties of Ti-Zr coatings.

Rodríguez-Hernández MG, Jiménez O, Alvarado-Hernández F, Flores M, Andrade E, Canto CE, Ávila C, Espinoza-Beltrán F.

J Mech Behav Biomed Mater. 2015 Sep;49:269-76. doi: 10.1016/j.jmbbm.2015.05.004. Epub 2015 May 14.


Role of Synchronous Activation of Cerebellar Purkinje Cell Ensembles in Multi-joint Movement Control.

Hoogland TM, De Gruijl JR, Witter L, Canto CB, De Zeeuw CI.

Curr Biol. 2015 May 4;25(9):1157-65. doi: 10.1016/j.cub.2015.03.009. Epub 2015 Apr 2.


SIRT1 enhances glucose tolerance by potentiating brown adipose tissue function.

Boutant M, Joffraud M, Kulkarni SS, García-Casarrubios E, García-Roves PM, Ratajczak J, Fernández-Marcos PJ, Valverde AM, Serrano M, Cantó C.

Mol Metab. 2014 Dec 18;4(2):118-31. doi: 10.1016/j.molmet.2014.12.008. eCollection 2015 Feb.


The molecular targets of resveratrol.

Kulkarni SS, Cantó C.

Biochim Biophys Acta. 2015 Jun;1852(6):1114-23. doi: 10.1016/j.bbadis.2014.10.005. Epub 2014 Oct 12. Review.


Pharmacological Inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle.

Pirinen E, Cantó C, Jo YS, Morato L, Zhang H, Menzies KJ, Williams EG, Mouchiroud L, Moullan N, Hagberg C, Li W, Timmers S, Imhof R, Verbeek J, Pujol A, van Loon B, Viscomi C, Zeviani M, Schrauwen P, Sauve AA, Schoonjans K, Auwerx J.

Cell Metab. 2014 Jun 3;19(6):1034-41. doi: 10.1016/j.cmet.2014.04.002. Epub 2014 May 8.


Regulation of energy metabolism and mitochondrial function in skeletal muscle during lipid overfeeding in healthy men.

Seyssel K, Alligier M, Meugnier E, Chanseaume E, Loizon E, Canto C, Disse E, Lambert-Porcheron S, Brozek J, Blond E, Rieusset J, Morio B, Laville M, Vidal H.

J Clin Endocrinol Metab. 2014 Jul;99(7):E1254-62. doi: 10.1210/jc.2013-4379. Epub 2014 Mar 31.


Mitochondrial response to nutrient availability and its role in metabolic disease.

Gao AW, Cantó C, Houtkooper RH.

EMBO Mol Med. 2014 May;6(5):580-9. doi: 10.1002/emmm.201303782. Review.


SIRT1 metabolic actions: Integrating recent advances from mouse models.

Boutant M, Cantó C.

Mol Metab. 2013 Oct 23;3(1):5-18. doi: 10.1016/j.molmet.2013.10.006. eCollection 2014 Feb. Review.


Hybrid model based on Genetic Algorithms and SVM applied to variable selection within fruit juice classification.

Fernandez-Lozano C, Canto C, Gestal M, Andrade-Garda JM, Rabuñal JR, Dorado J, Pazos A.

ScientificWorldJournal. 2013 Dec 10;2013:982438. doi: 10.1155/2013/982438. eCollection 2013.


Skeletal muscle mitochondria in the elderly: effects of physical fitness and exercise training.

Broskey NT, Greggio C, Boss A, Boutant M, Dwyer A, Schlueter L, Hans D, Gremion G, Kreis R, Boesch C, Canto C, Amati F.

J Clin Endocrinol Metab. 2014 May;99(5):1852-61. doi: 10.1210/jc.2013-3983. Epub 2014 Jan 17.


Architecture of spatial circuits in the hippocampal region.

Witter MP, Canto CB, Couey JJ, Koganezawa N, O'Reilly KC.

Philos Trans R Soc Lond B Biol Sci. 2013 Dec 23;369(1635):20120515. doi: 10.1098/rstb.2012.0515. Print 2014 Feb 5. Review.


In vivo measurement of the acetylation state of sirtuin substrates as a proxy for sirtuin activity.

Dominy J, Puigserver P, Cantó C.

Methods Mol Biol. 2013;1077:217-37. doi: 10.1007/978-1-62703-637-5_15.


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