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Combined neurosurgical and orbital intervention for spheno-orbital meningiomas - the Manchester experience.

Young J, Mdanat F, Dharmasena A, Cannon P, Leatherbarrow B, Hammerbeck-Ward C, Rutherford S, Ataullah S.

Orbit. 2019 Oct 28:1-7. doi: 10.1080/01676830.2019.1673782. [Epub ahead of print]


Death associated protein kinase 1 (DAPK-1) is increased in preeclampsia.

Yung C, MacDonald TM, Walker SP, Cannon P, Harper A, Pritchard N, Hannan NJ, Kaitu'u-Lino TJ, Tong S.

Placenta. 2019 Sep 24;88:1-7. doi: 10.1016/j.placenta.2019.09.010. [Epub ahead of print]


Sulfasalazine decreases soluble fms-like tyrosine kinase-1 secretion potentially via inhibition of upstream placental epidermal growth factor receptor signalling.

Hastie R, Brownfoot FC, Cannon P, Nguyen V, Tuohey L, Hannan NJ, Tong S, Kaitu'u-Lino TJ.

Placenta. 2019 Nov;87:53-57. doi: 10.1016/j.placenta.2019.09.004. Epub 2019 Sep 10.


Homologous Recombination-Based Genome Editing by Clade F AAVs Is Inefficient in the Absence of a Targeted DNA Break.

Rogers GL, Chen HY, Morales H, Cannon PM.

Mol Ther. 2019 Oct 2;27(10):1726-1736. doi: 10.1016/j.ymthe.2019.08.019. Epub 2019 Sep 9.


Rubroshiraia gen. nov., a second hypocrellin-producing genus in Shiraiaceae (Pleosporales).

Dai DQ, Wijayawardene NN, Tang LZ, Liu C, Han LH, Chu HL, Wang HB, Liao CF, Yang EF, Xu RF, Li YM, Hyde KD, Bhat DJ, Cannon PF.

MycoKeys. 2019 Aug 28;58:1-26. doi: 10.3897/mycokeys.58.36723. eCollection 2019.


Screening circulating proteins to identify biomarkers of fetal macrosomia.

Cruickshank T, Kaitu'u-Lino TJ, Cannon P, Harper A, Nguyen TV, Dane KM, Middleton AL, Kyritsis VP, Hastie R, Tong S, Walker SP, MacDonald TM.

BMC Res Notes. 2019 Sep 18;12(1):587. doi: 10.1186/s13104-019-4625-1.


Iatrogenic Morbidity of the Extraocular Muscle Biopsy.

Joganathan V, Cannon PS, Vishwanath M.

Ophthalmic Plast Reconstr Surg. 2019 Jul/Aug;35(4):408. doi: 10.1097/IOP.0000000000001396. No abstract available.


Return to Employment after Critical Illness and Its Association with Psychosocial Outcomes. A Systematic Review and Meta-Analysis.

McPeake J, Mikkelsen ME, Quasim T, Hibbert E, Cannon P, Shaw M, Ankori J, Iwashyna TJ, Haines KJ.

Ann Am Thorac Soc. 2019 Oct;16(10):1304-1311. doi: 10.1513/AnnalsATS.201903-248OC.


Factors associated with recruitment to randomised controlled trials in general practice: protocol for a systematic review.

Moffat KR, Cannon P, Shi W, Sullivan F.

Trials. 2019 May 10;20(1):266. doi: 10.1186/s13063-019-3354-z.


Circulating adrenomedullin mRNA is decreased in women destined to develop term preeclampsia.

Whigham CA, MacDonald TM, Walker SP, Pritchard N, Hannan NJ, Hastie R, Alwis N, Cannon P, Nguyen TV, Tong S, Kaitu'u-Lino T.

Pregnancy Hypertens. 2019 Apr;16:16-25. doi: 10.1016/j.preghy.2019.02.003. Epub 2019 Feb 10.


Functional Measures of Grip Strength and Gait Remain Altered Long-term in a Rat Model of Post-traumatic Elbow Contracture.

Reiter A, Kivitz G, Castile RM, Cannon P, Lakes E, Jacobs B, Allen K, Chamberlain AM, Lake SP.

J Biomech Eng. 2019 Apr 8. doi: 10.1115/1.4043433. [Epub ahead of print]


The Parkinson's phenome-traits associated with Parkinson's disease in a broadly phenotyped cohort.

Heilbron K, Noyce AJ, Fontanillas P, Alipanahi B, Nalls MA; 23andMe Research Team, Cannon P.

NPJ Parkinsons Dis. 2019 Mar 27;5:4. doi: 10.1038/s41531-019-0077-5. eCollection 2019.


Humanized Mouse Model of HIV-1 Latency with Enrichment of Latent Virus in PD-1+ and TIGIT+ CD4 T Cells.

Llewellyn GN, Seclén E, Wietgrefe S, Liu S, Chateau M, Pei H, Perkey K, Marsden MD, Hinkley SJ, Paschon DE, Holmes MC, Zack JA, Louie SG, Haase AT, Cannon PM.

J Virol. 2019 May 1;93(10). pii: e02086-18. doi: 10.1128/JVI.02086-18. Print 2019 May 15.


Sulfasalazine reduces placental secretion of antiangiogenic factors, up-regulates the secretion of placental growth factor and rescues endothelial dysfunction.

Brownfoot FC, Hannan NJ, Cannon P, Nguyen V, Hastie R, Parry LJ, Senadheera S, Tuohey L, Tong S, Kaitu'u-Lino TJ.

EBioMedicine. 2019 Mar;41:636-648. doi: 10.1016/j.ebiom.2019.02.013. Epub 2019 Feb 26.


Land-sparing agriculture sustains higher levels of avian functional diversity than land sharing.

Cannon PG, Gilroy JJ, Tobias JA, Anderson A, Haugaasen T, Edwards DP.

Glob Chang Biol. 2019 May;25(5):1576-1590. doi: 10.1111/gcb.14601. Epub 2019 Mar 13.


Circulating GATA2 mRNA is decreased among women destined to develop preeclampsia and may be of endothelial origin.

Whigham CA, MacDonald TM, Walker SP, Pritchard N, Hannan NJ, Cannon P, Nguyen TV, Hastie R, Tong S, Kaitu'u-Lino TJ.

Sci Rep. 2019 Jan 18;9(1):235. doi: 10.1038/s41598-018-36645-0.


Reprogramming the antigen specificity of B cells using genome-editing technologies.

Voss JE, Gonzalez-Martin A, Andrabi R, Fuller RP, Murrell B, McCoy LE, Porter K, Huang D, Li W, Sok D, Le K, Briney B, Chateau M, Rogers G, Hangartner L, Feeney AJ, Nemazee D, Cannon P, Burton DR.

Elife. 2019 Jan 17;8. pii: e42995. doi: 10.7554/eLife.42995.


EGFR (Epidermal Growth Factor Receptor) Signaling and the Mitochondria Regulate sFlt-1 (Soluble FMS-Like Tyrosine Kinase-1) Secretion.

Hastie R, Brownfoot FC, Pritchard N, Hannan NJ, Cannon P, Nguyen V, Palmer K, Beard S, Tong S, Kaitu'u-Lino TJ.

Hypertension. 2019 Mar;73(3):659-670. doi: 10.1161/HYPERTENSIONAHA.118.12300.


Disulfiram inhibits placental soluble FMS-like tyrosine kinase-1 and soluble endoglin secretion independent of the proteasome.

Hastie R, Ye L, Hannan NJ, Brownfoot FC, Cannon P, Nguyen V, Tong S, Kaitu'u-Lino TJ.

Pregnancy Hypertens. 2018 Oct;14:125-130. doi: 10.1016/j.preghy.2018.09.005. Epub 2018 Sep 21.


Rethinking bibliotherapy: a neurorhetoric narratology model for addiction treatment.

Cannon P.

Health Info Libr J. 2018 Dec;35(4):331-335. doi: 10.1111/hir.12239.


Protect NIH's DNA advisory committee.

Adelman ZN, Albritton LM, Boris-Lawrie K, Buchmeier MJ, Cannon P, Cho M, DiGiusto D, Donahue JK, Federoff HJ, Hammarskjold ML, Hardison AD, Hearing P, Lee B, Lee DA, Porteus MH, Ross LF, Ross SR, Wooley DP, Zoloth L.

Science. 2018 Oct 26;362(6413):409-410. doi: 10.1126/science.aav2483. No abstract available.


Effect of sildenafil citrate on circulating levels of sFlt-1 in preeclampsia.

Brownfoot FC, Tong S, Hannan NJ, Cannon P, Nguyen V, Kaitu'u-Lino TJ.

Pregnancy Hypertens. 2018 Jul;13:1-6. doi: 10.1016/j.preghy.2018.04.011. Epub 2018 Apr 11.


Assessing the sensitivity of placental growth factor and soluble fms-like tyrosine kinase 1 at 36 weeks' gestation to predict small-for-gestational-age infants or late-onset preeclampsia: a prospective nested case-control study.

MacDonald TM, Tran C, Kaitu'u-Lino TJ, Brennecke SP, Hiscock RJ, Hui L, Dane KM, Middleton AL, Cannon P, Walker SP, Tong S.

BMC Pregnancy Childbirth. 2018 Aug 31;18(1):354. doi: 10.1186/s12884-018-1992-x.


Exogenous CXCL4 infusion inhibits macrophage phagocytosis by limiting CD36 signalling to enhance post-myocardial infarction cardiac dilation and mortality.

Lindsey ML, Jung M, Yabluchanskiy A, Cannon PL, Iyer RP, Flynn ER, DeLeon-Pennell KY, Valerio FM, Harrison CL, Ripplinger CM, Hall ME, Ma Y.

Cardiovasc Res. 2019 Feb 1;115(2):395-408. doi: 10.1093/cvr/cvy211.


Self-report data as a tool for subtype identification in genetically-defined Parkinson's Disease.

Winslow AR, Hyde CL, Wilk JB, Eriksson N, Cannon P, Miller MR, Hirst WD.

Sci Rep. 2018 Aug 28;8(1):12992. doi: 10.1038/s41598-018-30843-6.


Real-time superchannel transmission over 10,500 km submarine link at 4.66 b/s/Hz spectral efficiency.

Kumpera A, Dominic V, Awadalla A, Dardis L, Rahn J, Sanders S, Mitchell M, Mertz P, Shartle G, Jackson S, Blakey S, Sokar M, Krause D, Sun H, Wu KT, Cannon P.

Opt Express. 2018 Jun 11;26(12):15039-15044. doi: 10.1364/OE.26.015039.


Deciphering the biology of Cryptophyllachora eurasiatica gen. et sp. nov., an often cryptic pathogen of an allergenic weed, Ambrosia artemisiifolia.

Kiss L, Kovács GM, Bóka K, Bohár G, Bohárné KV, Németh MZ, Takamatsu S, Shin HD, Hayova V, Nischwitz C, Seier MK, Evans HC, Cannon PF, Ash GJ, Shivas RG, Müller-Schärer H.

Sci Rep. 2018 Jul 17;8(1):10806. doi: 10.1038/s41598-018-29102-5.


Intrinsic apoptosis circumvents the functional decline of circulating platelets but does not cause the storage lesion.

Pleines I, Lebois M, Gangatirkar P, Au AE, Lane RM, Henley KJ, Kauppi M, Corbin J, Cannon P, Bernardini J, Alwis I, Jarman KE, Ellis S, Metcalf D, Jackson SP, Schoenwaelder SM, Kile BT, Josefsson EC.

Blood. 2018 Jul 12;132(2):197-209. doi: 10.1182/blood-2017-11-816355. Epub 2018 May 21.


The Mouse Heart Attack Research Tool 1.0 database.

DeLeon-Pennell KY, Iyer RP, Ma Y, Yabluchanskiy A, Zamilpa R, Chiao YA, Cannon PL, Kaplan A, Cates CA, Flynn ER, Halade GV, de Castro Brás LE, Lindsey ML.

Am J Physiol Heart Circ Physiol. 2018 Sep 1;315(3):H522-H530. doi: 10.1152/ajpheart.00172.2018. Epub 2018 May 18.


Selective Methylmagnesium Chloride Mediated Acetylations of Isosorbide: A Route to Powerful Nitric Oxide Donor Furoxans.

Kielty P, Smith DA, Cannon P, Carty MP, Kennedy M, McArdle P, Singer RJ, Aldabbagh F.

Org Lett. 2018 May 18;20(10):3025-3029. doi: 10.1021/acs.orglett.8b01060. Epub 2018 Apr 26.


Combining metformin and esomeprazole is additive in reducing sFlt-1 secretion and decreasing endothelial dysfunction - implications for treating preeclampsia.

Kaitu'u-Lino TJ, Brownfoot FC, Beard S, Cannon P, Hastie R, Nguyen TV, Binder NK, Tong S, Hannan NJ.

PLoS One. 2018 Feb 21;13(2):e0188845. doi: 10.1371/journal.pone.0188845. eCollection 2018.


Registered Replication Report: Dijksterhuis and van Knippenberg (1998).

O'Donnell M, Nelson LD, Ackermann E, Aczel B, Akhtar A, Aldrovandi S, Alshaif N, Andringa R, Aveyard M, Babincak P, Balatekin N, Baldwin SA, Banik G, Baskin E, Bell R, Białobrzeska O, Birt AR, Boot WR, Braithwaite SR, Briggs JC, Buchner A, Budd D, Budzik K, Bullens L, Bulley RL, Cannon PR, Cantarero K, Cesario J, Chambers S, Chartier CR, Chekroun P, Chong C, Cleeremans A, Coary SP, Coulthard J, Cramwinckel FM, Denson TF, Díaz-Lago M, DiDonato TE, Drummond A, Eberlen J, Ebersbach T, Edlund JE, Finnigan KM, Fisher J, Frankowska N, García-Sánchez E, Golom FD, Graves AJ, Greenberg K, Hanioti M, Hansen HA, Harder JA, Harrell ER, Hartanto A, Inzlicht M, Johnson DJ, Karpinski A, Keller VN, Klein O, Koppel L, Krahmer E, Lantian A, Larson MJ, Légal JB, Lucas RE, Lynott D, Magaldino CM, Massar K, McBee MT, McLatchie N, Melia N, Mensink MC, Mieth L, Moore-Berg S, Neeser G, Newell BR, Noordewier MK, Ali Özdoğru A, Pantazi M, Parzuchowski M, Peters K, Philipp MC, Pollmann MMH, Rentzelas P, Rodríguez-Bailón R, Philipp Röer J, Ropovik I, Roque NA, Rueda C, Rutjens BT, Sackett K, Salamon J, Sánchez-Rodríguez Á, Saunders B, Schaafsma J, Schulte-Mecklenbeck M, Shanks DR, Sherman MF, Steele KM, Steffens NK, Sun J, Susa KJ, Szaszi B, Szollosi A, Tamayo RM, Tinghög G, Tong YY, Tweten C, Vadillo MA, Valcarcel D, Van der Linden N, van Elk M, van Harreveld F, Västfjäll D, Vazire S, Verduyn P, Williams MN, Willis GB, Wood SE, Yang C, Zerhouni O, Zheng R, Zrubka M.

Perspect Psychol Sci. 2018 Mar;13(2):268-294. doi: 10.1177/1745691618755704. Epub 2018 Feb 21.


HIV-1 infection of microglial cells in a reconstituted humanized mouse model and identification of compounds that selectively reverse HIV latency.

Llewellyn GN, Alvarez-Carbonell D, Chateau M, Karn J, Cannon PM.

J Neurovirol. 2018 Apr;24(2):192-203. doi: 10.1007/s13365-017-0604-2. Epub 2017 Dec 18.


Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR-Cas9 genome-editing efficiency.

Canny MD, Moatti N, Wan LCK, Fradet-Turcotte A, Krasner D, Mateos-Gomez PA, Zimmermann M, Orthwein A, Juang YC, Zhang W, Noordermeer SM, Seclen E, Wilson MD, Vorobyov A, Munro M, Ernst A, Ng TF, Cho T, Cannon PM, Sidhu SS, Sicheri F, Durocher D.

Nat Biotechnol. 2018 Jan;36(1):95-102. doi: 10.1038/nbt.4021. Epub 2017 Nov 27.


Altered B-lymphopoiesis in mice with deregulated thrombopoietin signaling.

Au AE, Lebois M, Sim SA, Cannon P, Corbin J, Gangatirkar P, Hyland CD, Moujalled D, Rutgersson A, Yassinson F, Kile BT, Mason KD, Ng AP, Alexander WS, Josefsson EC.

Sci Rep. 2017 Nov 2;7(1):14953. doi: 10.1038/s41598-017-15023-2.


Activating Transcription Factor 3 Is Reduced in Preeclamptic Placentas and Negatively Regulates sFlt-1 (Soluble fms-Like Tyrosine Kinase 1), Soluble Endoglin, and Proinflammatory Cytokines in Placenta.

Kaitu'u-Lino TJ, Brownfoot FC, Hastie R, Chand A, Cannon P, Deo M, Tuohey L, Whitehead C, Hannan NJ, Tong S.

Hypertension. 2017 Nov;70(5):1014-1024. doi: 10.1161/HYPERTENSIONAHA.117.09548. Epub 2017 Sep 25.


Periodontal-induced chronic inflammation triggers macrophage secretion of Ccl12 to inhibit fibroblast-mediated cardiac wound healing.

DeLeon-Pennell KY, Iyer RP, Ero OK, Cates CA, Flynn ER, Cannon PL, Jung M, Shannon D, Garrett MR, Buchanan W, Hall ME, Ma Y, Lindsey ML.

JCI Insight. 2017 Sep 21;2(18). pii: 94207. doi: 10.1172/jci.insight.94207. eCollection 2017 Sep 21.


Gene Therapy Approaches to Human Immunodeficiency Virus and Other Infectious Diseases.

Rogers GL, Cannon PM.

Hematol Oncol Clin North Am. 2017 Oct;31(5):883-895. doi: 10.1016/j.hoc.2017.06.008. Review.


Resveratrol inhibits release of soluble fms-like tyrosine kinase (sFlt-1) and soluble endoglin and improves vascular dysfunction - implications as a preeclampsia treatment.

Hannan NJ, Brownfoot FC, Cannon P, Deo M, Beard S, Nguyen TV, Palmer KR, Tong S, Kaitu'u-Lino TJ.

Sci Rep. 2017 May 12;7(1):1819. doi: 10.1038/s41598-017-01993-w.


C-tactile afferent stimulating touch carries a positive affective value.

Pawling R, Cannon PR, McGlone FP, Walker SC.

PLoS One. 2017 Mar 10;12(3):e0173457. doi: 10.1371/journal.pone.0173457. eCollection 2017.


Spatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression.

Kalkavan H, Sharma P, Kasper S, Helfrich I, Pandyra AA, Gassa A, Virchow I, Flatz L, Brandenburg T, Namineni S, Heikenwalder M, Höchst B, Knolle PA, Wollmann G, von Laer D, Drexler I, Rathbun J, Cannon PM, Scheu S, Bauer J, Chauhan J, Häussinger D, Willimsky G, Löhning M, Schadendorf D, Brandau S, Schuler M, Lang PA, Lang KS.

Nat Commun. 2017 Mar 1;8:14447. doi: 10.1038/ncomms14447.


Transgenic overexpression of macrophage matrix metalloproteinase-9 exacerbates age-related cardiac hypertrophy, vessel rarefaction, inflammation, and fibrosis.

Toba H, Cannon PL, Yabluchanskiy A, Iyer RP, D'Armiento J, Lindsey ML.

Am J Physiol Heart Circ Physiol. 2017 Mar 1;312(3):H375-H383. doi: 10.1152/ajpheart.00633.2016. Epub 2016 Dec 23.


Epidermal Growth Factor Rescues Endothelial Dysfunction in Primary Human Tissues In Vitro.

Hastie R, Tong S, Hannan NJ, Brownfoot F, Cannon P, Kaitu'u-Lino TJ.

Reprod Sci. 2017 Sep;24(9):1245-1252. doi: 10.1177/1933719116681516. Epub 2016 Dec 5. Review.


Preclinical development and qualification of ZFN-mediated CCR5 disruption in human hematopoietic stem/progenitor cells.

DiGiusto DL, Cannon PM, Holmes MC, Li L, Rao A, Wang J, Lee G, Gregory PD, Kim KA, Hayward SB, Meyer K, Exline C, Lopez E, Henley J, Gonzalez N, Bedell V, Stan R, Zaia JA.

Mol Ther Methods Clin Dev. 2016 Nov 9;3:16067. eCollection 2016.


Steroid sulfatase is increased in the placentas and whole blood of women with early-onset preeclampsia.

Gratton AM, Ye L, Brownfoot FC, Hannan NJ, Whitehead C, Cannon P, Deo M, Fuller PJ, Tong S, Kaitu'u-Lino TJ.

Placenta. 2016 Dec;48:72-79. doi: 10.1016/j.placenta.2016.10.008. Epub 2016 Oct 15.


Nuclear factor of activated T-cells (NFAT) regulates soluble fms-like tyrosine kinase-1 secretion (sFlt-1) from human placenta.

Ye L, Gratton A, Hannan NJ, Cannon P, Deo M, Palmer KR, Tong S, Kaitu'u-Lino TJ, Brownfoot FC.

Placenta. 2016 Dec;48:110-118. doi: 10.1016/j.placenta.2016.10.013. Epub 2016 Oct 21.


Clinical Applications of Genome Editing to HIV Cure.

Wang CX, Cannon PM.

AIDS Patient Care STDS. 2016 Dec;30(12):539-544. Epub 2016 Nov 17.


A Cure for HIV Infection: "Not in My Lifetime" or "Just Around the Corner"?

Lederman MM, Cannon PM, Currier JS, June CH, Kiem HP, Kuritzkes DR, Lewin SR, Margolis DM, McCune JM, Mellors JW, Schacker TW, Sekaly RP, Tebas P, Walker BD, Douek DC.

Pathog Immun. 2016 Spring;1(1):154-164.


Early matrix metalloproteinase-9 inhibition post-myocardial infarction worsens cardiac dysfunction by delaying inflammation resolution.

Iyer RP, de Castro Brás LE, Patterson NL, Bhowmick M, Flynn ER, Asher M, Cannon PL, Deleon-Pennell KY, Fields GB, Lindsey ML.

J Mol Cell Cardiol. 2016 Nov;100:109-117. doi: 10.1016/j.yjmcc.2016.10.005. Epub 2016 Oct 13.


Finding Out What It's About.

Cannon PN.

Northwest Dent. 2016 Sep;95(4):7. No abstract available.


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