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Items: 26


Recapitulation and Reversal of Schizophrenia-Related Phenotypes in Setd1a-Deficient Mice.

Mukai J, Cannavò E, Crabtree GW, Sun Z, Diamantopoulou A, Thakur P, Chang CY, Cai Y, Lomvardas S, Takata A, Xu B, Gogos JA.

Neuron. 2019 Nov 6;104(3):471-487.e12. doi: 10.1016/j.neuron.2019.09.014. Epub 2019 Oct 9.


Stepwise 5' DNA end-specific resection of DNA breaks by the Mre11-Rad50-Xrs2 and Sae2 nuclease ensemble.

Cannavo E, Reginato G, Cejka P.

Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5505-5513. doi: 10.1073/pnas.1820157116. Epub 2019 Feb 28.


Regulatory control of DNA end resection by Sae2 phosphorylation.

Cannavo E, Johnson D, Andres SN, Kissling VM, Reinert JK, Garcia V, Erie DA, Hess D, Thomä NH, Enchev RI, Peter M, Williams RS, Neale MJ, Cejka P.

Nat Commun. 2018 Oct 1;9(1):4016. doi: 10.1038/s41467-018-06417-5.


Physiological protein blocks direct the Mre11-Rad50-Xrs2 and Sae2 nuclease complex to initiate DNA end resection.

Reginato G, Cannavo E, Cejka P.

Genes Dev. 2017 Dec 1;31(23-24):2325-2330. doi: 10.1101/gad.308254.117. Epub 2018 Jan 10.


Promoter shape varies across populations and affects promoter evolution and expression noise.

Schor IE, Degner JF, Harnett D, Cannavò E, Casale FP, Shim H, Garfield DA, Birney E, Stephens M, Stegle O, Furlong EE.

Nat Genet. 2017 Apr;49(4):550-558. doi: 10.1038/ng.3791. Epub 2017 Feb 13.


Genetic variants regulating expression levels and isoform diversity during embryogenesis.

Cannavò E, Koelling N, Harnett D, Garfield D, Casale FP, Ciglar L, Gustafson HE, Viales RR, Marco-Ferreres R, Degner JF, Zhao B, Stegle O, Birney E, Furlong EE.

Nature. 2017 Jan 19;541(7637):402-406. doi: 10.1038/nature20802. Epub 2016 Dec 26.


Phosphorylated CtIP Functions as a Co-factor of the MRE11-RAD50-NBS1 Endonuclease in DNA End Resection.

Anand R, Ranjha L, Cannavo E, Cejka P.

Mol Cell. 2016 Dec 1;64(5):940-950. doi: 10.1016/j.molcel.2016.10.017. Epub 2016 Nov 23.


Xrs2 Dependent and Independent Functions of the Mre11-Rad50 Complex.

Oh J, Al-Zain A, Cannavo E, Cejka P, Symington LS.

Mol Cell. 2016 Oct 20;64(2):405-415. doi: 10.1016/j.molcel.2016.09.011. Epub 2016 Oct 13.


Shadow Enhancers Are Pervasive Features of Developmental Regulatory Networks.

Cannavò E, Khoueiry P, Garfield DA, Geeleher P, Zichner T, Gustafson EH, Ciglar L, Korbel JO, Furlong EE.

Curr Biol. 2016 Jan 11;26(1):38-51. doi: 10.1016/j.cub.2015.11.034. Epub 2015 Dec 10.


Sae2 promotes dsDNA endonuclease activity within Mre11-Rad50-Xrs2 to resect DNA breaks.

Cannavo E, Cejka P.

Nature. 2014 Oct 2;514(7520):122-5. doi: 10.1038/nature13771. Epub 2014 Sep 17.


High expression of the mismatch repair protein MSH6 is associated with poor patient survival in melanoma.

Alvino E, Passarelli F, Cannavò E, Fortes C, Mastroeni S, Caporali S, Jiricny J, Cappellini GC, Scoppola A, Marchetti P, Modesti A, D'Atri S.

Am J Clin Pathol. 2014 Jul;142(1):121-32. doi: 10.1309/AJCPCX2D9YULBBLG.


Analysis of multiply spliced transcripts in lymphoid tissue reservoirs of rhesus macaques infected with RT-SHIV during HAART.

Deere JD, Kauffman RC, Cannavo E, Higgins J, Villalobos A, Adamson L, Schinazi RF, Luciw PA, North TW.

PLoS One. 2014 Feb 5;9(2):e87914. doi: 10.1371/journal.pone.0087914. eCollection 2014.


Relationship of DNA degradation by Saccharomyces cerevisiae exonuclease 1 and its stimulation by RPA and Mre11-Rad50-Xrs2 to DNA end resection.

Cannavo E, Cejka P, Kowalczykowski SC.

Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):E1661-8. doi: 10.1073/pnas.1305166110. Epub 2013 Apr 15.


Impact of genomic structural variation in Drosophila melanogaster based on population-scale sequencing.

Zichner T, Garfield DA, Rausch T, Stütz AM, Cannavó E, Braun M, Furlong EE, Korbel JO.

Genome Res. 2013 Mar;23(3):568-79. doi: 10.1101/gr.142646.112. Epub 2012 Dec 6.


DNA end resection by Dna2-Sgs1-RPA and its stimulation by Top3-Rmi1 and Mre11-Rad50-Xrs2.

Cejka P, Cannavo E, Polaczek P, Masuda-Sasa T, Pokharel S, Campbell JL, Kowalczykowski SC.

Nature. 2010 Sep 2;467(7311):112-6. doi: 10.1038/nature09355.


Viral decay kinetics in the highly active antiretroviral therapy-treated rhesus macaque model of AIDS.

Deere JD, Higgins J, Cannavo E, Villalobos A, Adamson L, Fromentin E, Schinazi RF, Luciw PA, North TW.

PLoS One. 2010 Jul 23;5(7):e11640. doi: 10.1371/journal.pone.0011640.


Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents.

Kratz K, Schöpf B, Kaden S, Sendoel A, Eberhard R, Lademann C, Cannavó E, Sartori AA, Hengartner MO, Jiricny J.

Cell. 2010 Jul 9;142(1):77-88. doi: 10.1016/j.cell.2010.06.022.


Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.

Cannavo E, Gerrits B, Marra G, Schlapbach R, Jiricny J.

J Biol Chem. 2007 Feb 2;282(5):2976-86. Epub 2006 Dec 4.


Expression of the MutL homologue hMLH3 in human cells and its role in DNA mismatch repair.

Cannavo E, Marra G, Sabates-Bellver J, Menigatti M, Lipkin SM, Fischer F, Cejka P, Jiricny J.

Cancer Res. 2005 Dec 1;65(23):10759-66.


In vitro antitumour activity of resveratrol in human melanoma cells sensitive or resistant to temozolomide.

Fuggetta MP, D'Atri S, Lanzilli G, Tricarico M, Cannavò E, Zambruno G, Falchetti R, Ravagnan G.

Melanoma Res. 2004 Jun;14(3):189-96.


Differential killing of mismatch repair-deficient and -proficient cells: towards the therapy of tumors with microsatellite instability.

Cejka P, Marra G, Hemmerle C, Cannavó E, Storchova Z, Jiricny J.

Cancer Res. 2003 Dec 1;63(23):8113-7.


Methylation-induced G(2)/M arrest requires a full complement of the mismatch repair protein hMLH1.

Cejka P, Stojic L, Mojas N, Russell AM, Heinimann K, Cannavó E, di Pietro M, Marra G, Jiricny J.

EMBO J. 2003 May 1;22(9):2245-54.


Biallelic somatic inactivation of the mismatch repair gene MLH1 in a primary skin melanoma.

Castiglia D, Pagani E, Alvino E, Vernole P, Marra G, Cannavò E, Jiricny J, Zambruno G, D'Atri S.

Genes Chromosomes Cancer. 2003 Jun;37(2):165-75.


Phenotypic analysis of hMSH2 mutations in mouse cells carrying human chromosomes.

Marra G, D'Atri S, Yan H, Perrera C, Cannavo' E, Vogelstein B, Jiricny J.

Cancer Res. 2001 Nov 1;61(21):7719-21.


Effect of Saquinavir on proliferation and telomerase activity of human peripheral blood mononuclear cells.

Franzese O, Lombardi A, Comandini A, Cannavò E, Testorelli C, Cirello I, Bonmassar E.

Life Sci. 2001 Aug 17;69(13):1509-20.


Effect of prostaglandin A1 on proliferation and telomerase activity of human melanoma cells in vitro.

Franzese O, Comandini A, Cannavò E, Pepponi R, Falcinelli S, Graziani G, Bonmassar E.

Melanoma Res. 1998 Aug;8(4):323-8.


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