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Genetic deletion of soluble 5'-nucleotidase II reduces body weight gain and insulin resistance induced by a high-fat diet.

Johanns M, Kviklyte S, Chuang SJ, Corbeels K, Jacobs R, Herinckx G, Vertommen D, Schakman O, Duparc T, Cani PD, Bouzin C, Andersén H, Bohlooly-Y M, Van der Schueren B, Oscarsson J, Rider MH.

Mol Genet Metab. 2019 Feb 14. pii: S1096-7192(18)30720-0. doi: 10.1016/j.ymgme.2019.01.017. [Epub ahead of print]


Butyricimonas faecalis sp. nov., isolated from human faeces and emended description of the genus Butyricimonas.

Le Roy T, Van der Smissen P, Paquot A, Delzenne N, Muccioli GG, Collet JF, Cani PD.

Int J Syst Evol Microbiol. 2019 Mar;69(3):833-838. doi: 10.1099/ijsem.0.003249. Epub 2019 Feb 1.


Intestinal epithelial N-acylphosphatidylethanolamine phospholipase D links dietary fat to metabolic adaptations in obesity and steatosis.

Everard A, Plovier H, Rastelli M, Van Hul M, de Wouters d'Oplinter A, Geurts L, Druart C, Robine S, Delzenne NM, Muccioli GG, de Vos WM, Luquet S, Flamand N, Di Marzo V, Cani PD.

Nat Commun. 2019 Jan 28;10(1):457. doi: 10.1038/s41467-018-08051-7.


Targeting gut microbiota with a complex mix of dietary fibers improves metabolic diseases.

Cani PD.

Kidney Int. 2019 Jan;95(1):14-16. doi: 10.1016/j.kint.2018.11.012. No abstract available.


Microbiota and metabolites in metabolic diseases.

Cani PD.

Nat Rev Endocrinol. 2019 Feb;15(2):69-70. doi: 10.1038/s41574-018-0143-9. No abstract available.


Elevated high density lipoprotein cholesterol and low grade systemic inflammation is associated with increased gut permeability in normoglycemic men.

Robertson MD, Pedersen C, Hinton PJ, Mendis ASJR, Cani PD, Griffin BA.

Nutr Metab Cardiovasc Dis. 2018 Dec;28(12):1296-1303. doi: 10.1016/j.numecd.2018.07.006. Epub 2018 Aug 1.


Erratum. The Transplantation of ω3 PUFA-Altered Gut Microbiota of fat-1 Mice to Wild-Type Littermates Prevents Obesity and Associated Metabolic Disorders. Diabetes 2018;67:1512-1523.

Bidu C, Escoula Q, Bellenger S, Spor A, Galan M, Geissler A, Bouchot A, Dardevet D, Morio-Liondor B, Cani PD, Lagrost L, Narce M, Bellenger J.

Diabetes. 2019 Jan;68(1):235. doi: 10.2337/db19-er01a. Epub 2018 Nov 19. No abstract available.


Inflammation and Gut-Brain Axis During Type 2 Diabetes: Focus on the Crosstalk Between Intestinal Immune Cells and Enteric Nervous System.

Bessac A, Cani PD, Meunier E, Dietrich G, Knauf C.

Front Neurosci. 2018 Oct 10;12:725. doi: 10.3389/fnins.2018.00725. eCollection 2018. Review.


Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer.

Singh V, Yeoh BS, Chassaing B, Xiao X, Saha P, Aguilera Olvera R, Lapek JD Jr, Zhang L, Wang WB, Hao S, Flythe MD, Gonzalez DJ, Cani PD, Conejo-Garcia JR, Xiong N, Kennett MJ, Joe B, Patterson AD, Gewirtz AT, Vijay-Kumar M.

Cell. 2018 Oct 18;175(3):679-694.e22. doi: 10.1016/j.cell.2018.09.004.


Klebsiella oxytoca expands in cancer cachexia and acts as a gut pathobiont contributing to intestinal dysfunction.

Pötgens SA, Brossel H, Sboarina M, Catry E, Cani PD, Neyrinck AM, Delzenne NM, Bindels LB.

Sci Rep. 2018 Aug 17;8(1):12321. doi: 10.1038/s41598-018-30569-5.


Severe obesity and gut microbiota: does bariatric surgery really reset the system?

Cani PD.

Gut. 2019 Jan;68(1):5-6. doi: 10.1136/gutjnl-2018-316815. Epub 2018 Jul 10. No abstract available.


Impact of Intestinal Peptides on the Enteric Nervous System: Novel Approaches to Control Glucose Metabolism and Food Intake.

Abot A, Cani PD, Knauf C.

Front Endocrinol (Lausanne). 2018 Jun 22;9:328. doi: 10.3389/fendo.2018.00328. eCollection 2018. Review.


Human gut microbiome: hopes, threats and promises.

Cani PD.

Gut. 2018 Sep;67(9):1716-1725. doi: 10.1136/gutjnl-2018-316723. Epub 2018 Jun 22. Review.


The gut microbiota metabolite indole alleviates liver inflammation in mice.

Beaumont M, Neyrinck AM, Olivares M, Rodriguez J, de Rocca Serra A, Roumain M, Bindels LB, Cani PD, Evenepoel P, Muccioli GG, Demoulin JB, Delzenne NM.

FASEB J. 2018 Jun 15:fj201800544. doi: 10.1096/fj.201800544. [Epub ahead of print]


Prebiotics Supplementation Impact on the Reinforcing and Motivational Aspect of Feeding.

Delbès AS, Castel J, Denis RGP, Morel C, Quiñones M, Everard A, Cani PD, Massiera F, Luquet SH.

Front Endocrinol (Lausanne). 2018 May 29;9:273. doi: 10.3389/fendo.2018.00273. eCollection 2018.


Gut microbiota-mediated inflammation in obesity: a link with gastrointestinal cancer.

Cani PD, Jordan BF.

Nat Rev Gastroenterol Hepatol. 2018 Nov;15(11):671-682. doi: 10.1038/s41575-018-0025-6. Review.


The DPP-4 inhibitor vildagliptin impacts the gut microbiota and prevents disruption of intestinal homeostasis induced by a Western diet in mice.

Olivares M, Neyrinck AM, Pötgens SA, Beaumont M, Salazar N, Cani PD, Bindels LB, Delzenne NM.

Diabetologia. 2018 Aug;61(8):1838-1848. doi: 10.1007/s00125-018-4647-6. Epub 2018 May 25.


The Transplantation of ω3 PUFA-Altered Gut Microbiota of fat-1 Mice to Wild-Type Littermates Prevents Obesity and Associated Metabolic Disorders.

Bidu C, Escoula Q, Bellenger S, Spor A, Galan M, Geissler A, Bouchot A, Dardevet D, Morio B, Cani PD, Lagrost L, Narce M, Bellenger J.

Diabetes. 2018 Aug;67(8):1512-1523. doi: 10.2337/db17-1488. Epub 2018 May 23. Erratum in: Diabetes. 2019 Jan;68(1):235.


Increased gut permeability in cancer cachexia: mechanisms and clinical relevance.

Bindels LB, Neyrinck AM, Loumaye A, Catry E, Walgrave H, Cherbuy C, Leclercq S, Van Hul M, Plovier H, Pachikian B, Bermúdez-Humarán LG, Langella P, Cani PD, Thissen JP, Delzenne NM.

Oncotarget. 2018 Apr 6;9(26):18224-18238. doi: 10.18632/oncotarget.24804. eCollection 2018 Apr 6.


Inulin Improves Postprandial Hypertriglyceridemia by Modulating Gene Expression in the Small Intestine.

Hiel S, Neyrinck AM, Rodriguez J, Pachikian BD, Bouzin C, Thissen JP, Cani PD, Bindels LB, Delzenne NM.

Nutrients. 2018 Apr 25;10(5). pii: E532. doi: 10.3390/nu10050532.


Gut Microbes and Health: A Focus on the Mechanisms Linking Microbes, Obesity, and Related Disorders.

Rastelli M, Knauf C, Cani PD.

Obesity (Silver Spring). 2018 May;26(5):792-800. doi: 10.1002/oby.22175. Review.


Fecal Enterobacteriales enrichment is associated with increased in vivo intestinal permeability in humans.

Pedersen C, Ijaz UZ, Gallagher E, Horton F, Ellis RJ, Jaiyeola E, Duparc T, Russell-Jones D, Hinton P, Cani PD, La Ragione RM, Robertson MD.

Physiol Rep. 2018 Apr;6(7):e13649. doi: 10.14814/phy2.13649.


Wheat-derived arabinoxylan oligosaccharides with bifidogenic properties abolishes metabolic disorders induced by western diet in mice.

Neyrinck AM, Hiel S, Bouzin C, Campayo VG, Cani PD, Bindels LB, Delzenne NM.

Nutr Diabetes. 2018 Mar 7;8(1):15. doi: 10.1038/s41387-018-0019-z.


Galanin enhances systemic glucose metabolism through enteric Nitric Oxide Synthase-expressed neurons.

Abot A, Lucas A, Bautzova T, Bessac A, Fournel A, Le-Gonidec S, Valet P, Moro C, Cani PD, Knauf C.

Mol Metab. 2018 Apr;10:100-108. doi: 10.1016/j.molmet.2018.01.020. Epub 2018 Jan 31.


Implication of trans-11,trans-13 conjugated linoleic acid in the development of hepatic steatosis.

Pachikian BD, Druart C, Catry E, Bindels LB, Neyrinck AM, Larondelle Y, Cani PD, Delzenne NM.

PLoS One. 2018 Feb 1;13(2):e0192447. doi: 10.1371/journal.pone.0192447. eCollection 2018.


Akkermansia muciniphila induces gut microbiota remodelling and controls islet autoimmunity in NOD mice.

Hänninen A, Toivonen R, Pöysti S, Belzer C, Plovier H, Ouwerkerk JP, Emani R, Cani PD, De Vos WM.

Gut. 2018 Aug;67(8):1445-1453. doi: 10.1136/gutjnl-2017-314508. Epub 2017 Dec 21.


Size Effect on Lipid Nanocapsule-Mediated GLP-1 Secretion from Enteroendocrine L Cells.

Xu Y, Carradori D, Alhouayek M, Muccioli GG, Cani PD, Préat V, Beloqui A.

Mol Pharm. 2018 Jan 2;15(1):108-115. doi: 10.1021/acs.molpharmaceut.7b00742. Epub 2017 Dec 15.


Adipose Tissue Metabolism and Cancer Progression: Novel Insights from Gut Microbiota?

Jordan BF, Gourgue F, Cani PD.

Curr Pathobiol Rep. 2017;5(4):315-322. doi: 10.1007/s40139-017-0154-6. Epub 2017 Oct 24. Review.


Intestinal Ralstonia pickettii augments glucose intolerance in obesity.

Udayappan SD, Kovatcheva-Datchary P, Bakker GJ, Havik SR, Herrema H, Cani PD, Bouter KE, Belzer C, Witjes JJ, Vrieze A, de Sonnaville ESV, Chaplin A, van Raalte DH, Aalvink S, Dallinga-Thie GM, Heilig HGHJ, Bergström G, van der Meij S, van Wagensveld BA, Hoekstra JBL, Holleman F, Stroes ESG, Groen AK, Bäckhed F, de Vos WM, Nieuwdorp M.

PLoS One. 2017 Nov 22;12(11):e0181693. doi: 10.1371/journal.pone.0181693. eCollection 2017. Erratum in: PLoS One. 2018 Jan 30;13(1):e0192339.


Host-microbiota interaction induces bi-phasic inflammation and glucose intolerance in mice.

Molinaro A, Caesar R, Holm LM, Tremaroli V, Cani PD, Bäckhed F.

Mol Metab. 2017 Nov;6(11):1371-1380. doi: 10.1016/j.molmet.2017.08.016. Epub 2017 Sep 21.


Combined endogenous MR biomarkers to predict basal tumor oxygenation and response to hyperoxic challenge.

Cao-Pham TT, Joudiou N, Van Hul M, Bouzin C, Cani PD, Gallez B, Jordan BF.

NMR Biomed. 2017 Dec;30(12). doi: 10.1002/nbm.3836. Epub 2017 Oct 11.


Next-Generation Beneficial Microbes: The Case of Akkermansia muciniphila.

Cani PD, de Vos WM.

Front Microbiol. 2017 Sep 22;8:1765. doi: 10.3389/fmicb.2017.01765. eCollection 2017. Review.


Enteroendocrine Cells: Metabolic Relays between Microbes and Their Host.

Plovier H, Cani PD.

Endocr Dev. 2017;32:139-164. doi: 10.1159/000475736. Epub 2017 Aug 15. Review.


Reduced obesity, diabetes, and steatosis upon cinnamon and grape pomace are associated with changes in gut microbiota and markers of gut barrier.

Van Hul M, Geurts L, Plovier H, Druart C, Everard A, Ståhlman M, Rhimi M, Chira K, Teissedre PL, Delzenne NM, Maguin E, Guilbot A, Brochot A, Gérard P, Bäckhed F, Cani PD.

Am J Physiol Endocrinol Metab. 2018 Apr 1;314(4):E334-E352. doi: 10.1152/ajpendo.00107.2017. Epub 2017 Sep 5.


Ffar2 expression regulates leukaemic cell growth in vivo.

Bindels LB, Porporato PE, Ducastel S, Sboarina M, Neyrinck AM, Dewulf EM, Feron O, Lestavel S, Cani PD, Staels B, Sonveaux P, Delzenne NM.

Br J Cancer. 2017 Oct 24;117(9):1336-1340. doi: 10.1038/bjc.2017.307. Epub 2017 Sep 5.


A polyphenolic extract from green tea leaves activates fat browning in high-fat-diet-induced obese mice.

Neyrinck AM, Bindels LB, Geurts L, Van Hul M, Cani PD, Delzenne NM.

J Nutr Biochem. 2017 Nov;49:15-21. doi: 10.1016/j.jnutbio.2017.07.008. Epub 2017 Jul 24.


Gut cell metabolism shapes the microbiome.

Cani PD.

Science. 2017 Aug 11;357(6351):548-549. doi: 10.1126/science.aao2202. No abstract available.


Fat binding capacity and modulation of the gut microbiota both determine the effect of wheat bran fractions on adiposity.

Suriano F, Bindels LB, Verspreet J, Courtin CM, Verbeke K, Cani PD, Neyrinck AM, Delzenne NM.

Sci Rep. 2017 Jul 17;7(1):5621. doi: 10.1038/s41598-017-05698-y.


Interactions between gut microbes and host cells control gut barrier and metabolism.

Cani PD.

Int J Obes Suppl. 2016 Dec;6(Suppl 1):S28-S31. doi: 10.1038/ijosup.2016.6. Epub 2016 Nov 16. Review.


Spirulina Protects against Hepatic Inflammation in Aging: An Effect Related to the Modulation of the Gut Microbiota?

Neyrinck AM, Taminiau B, Walgrave H, Daube G, Cani PD, Bindels LB, Delzenne NM.

Nutrients. 2017 Jun 20;9(6). pii: E633. doi: 10.3390/nu9060633.


Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics.

Gibson GR, Hutkins R, Sanders ME, Prescott SL, Reimer RA, Salminen SJ, Scott K, Stanton C, Swanson KS, Cani PD, Verbeke K, Reid G.

Nat Rev Gastroenterol Hepatol. 2017 Aug;14(8):491-502. doi: 10.1038/nrgastro.2017.75. Epub 2017 Jun 14. Review.


Microbial Impact on Host Metabolism: Opportunities for Novel Treatments of Nutritional Disorders?

Plovier H, Cani PD.

Microbiol Spectr. 2017 Jun;5(3). doi: 10.1128/microbiolspec.BAD-0002-2016. Review.


[Optimization and safety assessment of Akkermansia muciniphila for human administration].

Plovier H, Cani PD.

Med Sci (Paris). 2017 Apr;33(4):373-375. doi: 10.1051/medsci/20173304002. Epub 2017 May 12. French. No abstract available.


Gut microbiota - at the intersection of everything?

Cani PD.

Nat Rev Gastroenterol Hepatol. 2017 Jun;14(6):321-322. doi: 10.1038/nrgastro.2017.54. Epub 2017 Apr 26.


Targeting the gut microbiota with inulin-type fructans: preclinical demonstration of a novel approach in the management of endothelial dysfunction.

Catry E, Bindels LB, Tailleux A, Lestavel S, Neyrinck AM, Goossens JF, Lobysheva I, Plovier H, Essaghir A, Demoulin JB, Bouzin C, Pachikian BD, Cani PD, Staels B, Dessy C, Delzenne NM.

Gut. 2018 Feb;67(2):271-283. doi: 10.1136/gutjnl-2016-313316. Epub 2017 Apr 4.


Transfer of dysbiotic gut microbiota has beneficial effects on host liver metabolism.

Nicolas S, Blasco-Baque V, Fournel A, Gilleron J, Klopp P, Waget A, Ceppo F, Marlin A, Padmanabhan R, Iacovoni JS, Tercé F, Cani PD, Tanti JF, Burcelin R, Knauf C, Cormont M, Serino M.

Mol Syst Biol. 2017 Mar 16;13(3):921. doi: 10.15252/msb.20167356.


Integrative Physiology: At the Crossroads of Nutrition, Microbiota, Animal Physiology, and Human Health.

Leulier F, MacNeil LT, Lee WJ, Rawls JF, Cani PD, Schwarzer M, Zhao L, Simpson SJ.

Cell Metab. 2017 Mar 7;25(3):522-534. doi: 10.1016/j.cmet.2017.02.001. Review.


Novel insight into the role of microbiota in colorectal surgery.

Bachmann R, Leonard D, Delzenne N, Kartheuser A, Cani PD.

Gut. 2017 Apr;66(4):738-749. doi: 10.1136/gutjnl-2016-312569. Epub 2017 Feb 2. Review.


Fermentable carbohydrate stimulates FFAR2-dependent colonic PYY cell expansion to increase satiety.

Brooks L, Viardot A, Tsakmaki A, Stolarczyk E, Howard JK, Cani PD, Everard A, Sleeth ML, Psichas A, Anastasovskaj J, Bell JD, Bell-Anderson K, Mackay CR, Ghatei MA, Bloom SR, Frost G, Bewick GA.

Mol Metab. 2016 Nov 4;6(1):48-60. doi: 10.1016/j.molmet.2016.10.011. eCollection 2017 Jan.


Can probiotics modulate human disease by impacting intestinal barrier function?

Bron PA, Kleerebezem M, Brummer RJ, Cani PD, Mercenier A, MacDonald TT, Garcia-Ródenas CL, Wells JM.

Br J Nutr. 2017 Jan;117(1):93-107. doi: 10.1017/S0007114516004037. Review.

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