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Items: 15


Lighting Up Clostridium Difficile: Reporting Gene Expression Using Fluorescent Lov Domains.

Buckley AM, Jukes C, Candlish D, Irvine JJ, Spencer J, Fagan RP, Roe AJ, Christie JM, Fairweather NF, Douce GR.

Sci Rep. 2016 Mar 21;6:23463. doi: 10.1038/srep23463.


Vaccination against Clostridium difficile using toxin fragments: Observations and analysis in animal models.

Spencer J, Leuzzi R, Buckley A, Irvine J, Candlish D, Scarselli M, Douce GR.

Gut Microbes. 2014 Mar-Apr;5(2):225-32. doi: 10.4161/gmic.27712. Epub 2014 Jan 22.


Protective efficacy induced by recombinant Clostridium difficile toxin fragments.

Leuzzi R, Spencer J, Buckley A, Brettoni C, Martinelli M, Tulli L, Marchi S, Luzzi E, Irvine J, Candlish D, Veggi D, Pansegrau W, Fiaschi L, Savino S, Swennen E, Cakici O, Oviedo-Orta E, Giraldi M, Baudner B, D'Urzo N, Maione D, Soriani M, Rappuoli R, Pizza M, Douce GR, Scarselli M.

Infect Immun. 2013 Aug;81(8):2851-60. doi: 10.1128/IAI.01341-12. Epub 2013 May 28.


Susceptibility of hamsters to Clostridium difficile isolates of differing toxinotype.

Buckley AM, Spencer J, Maclellan LM, Candlish D, Irvine JJ, Douce GR.

PLoS One. 2013 May 21;8(5):e64121. doi: 10.1371/journal.pone.0064121. Print 2013.


Infection of hamsters with the UK Clostridium difficile ribotype 027 outbreak strain R20291.

Buckley AM, Spencer J, Candlish D, Irvine JJ, Douce GR.

J Med Microbiol. 2011 Aug;60(Pt 8):1174-80. doi: 10.1099/jmm.0.028514-0. Epub 2011 Feb 17.


Virulence spectra of typed strains of Campylobacter jejuni from different sources: a blinded in vivo study.

Stewart-Tull DE, Coote JG, Thompson DH, Candlish D, Wardlaw AC, Candlish A.

J Med Microbiol. 2009 May;58(Pt 5):546-53. doi: 10.1099/jmm.0.005611-0.


Comparison of virulence-associated in vitro properties of typed strains of Campylobacter jejuni from different sources.

Coote JG, Stewart-Tull DE, Owen RJ, Bolton FJ, Siemer BL, Candlish D, Thompson DH, Wardlaw AC, On SL, Candlish A, Billcliffe B, Jordan PJ, Kristiansen K, Borman P.

J Med Microbiol. 2007 Jun;56(Pt 6):722-32.


Molecular interactions underlying the unusually high adenosine affinity of a novel Trypanosoma brucei nucleoside transporter.

Al-Salabi MI, Wallace LJ, Lüscher A, Mäser P, Candlish D, Rodenko B, Gould MK, Jabeen I, Ajith SN, de Koning HP.

Mol Pharmacol. 2007 Mar;71(3):921-9. Epub 2006 Dec 21.


Trypanosoma brucei: a survey of pyrimidine transport activities.

Gudin S, Quashie NB, Candlish D, Al-Salabi MI, Jarvis SM, Ranford-Cartwright LC, de Koning HP.

Exp Parasitol. 2006 Oct;114(2):118-25. Epub 2006 Apr 18.


Trypanosoma brucei: expression of multiple purine transporters prevents the development of allopurinol resistance.

Natto MJ, Wallace LJ, Candlish D, Al-Salabi MI, Coutts SE, de Koning HP.

Exp Parasitol. 2005 Feb;109(2):80-6. Epub 2005 Jan 8.


Selective transport of a new class of purine antimetabolites by the protozoan parasite Trypanosoma brucei.

Wallace LJ, Candlish D, Hagos A, Seley KL, de Koning HP.

Nucleosides Nucleotides Nucleic Acids. 2004 Oct;23(8-9):1441-4.


Cloning, heterologous expression, and in situ characterization of the first high affinity nucleobase transporter from a protozoan.

Burchmore RJ, Wallace LJ, Candlish D, Al-Salabi MI, Beal PR, Barrett MP, Baldwin SA, de Koning HP.

J Biol Chem. 2003 Jun 27;278(26):23502-7. Epub 2003 Apr 21.


Identification of oligomerization and drug-binding domains of the membrane fusion protein EmrA.

Borges-Walmsley MI, Beauchamp J, Kelly SM, Jumel K, Candlish D, Harding SE, Price NC, Walmsley AR.

J Biol Chem. 2003 Apr 11;278(15):12903-12. Epub 2002 Dec 13.


Different substrate recognition motifs of human and trypanosome nucleobase transporters. Selective uptake of purine antimetabolites.

Wallace LJ, Candlish D, De Koning HP.

J Biol Chem. 2002 Jul 19;277(29):26149-56. Epub 2002 May 9.


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