Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 90

1.

NOP receptor antagonism reduces alcohol drinking in male and female rats through mechanisms involving the central amygdala and ventral tegmental area.

Borruto AM, Fotio Y, Stopponi S, Brunori G, Petrella M, Caputi FF, Romualdi P, Candeletti S, Narendran R, Rorick-Kehn LM, Ubaldi M, Weiss F, Ciccocioppo R.

Br J Pharmacol. 2019 Nov 12. doi: 10.1111/bph.14915. [Epub ahead of print]

PMID:
31713848
2.

Activation of PPARγ Attenuates the Expression of Physical and Affective Nicotine Withdrawal Symptoms through Mechanisms Involving Amygdala and Hippocampus Neurotransmission.

Domi E, Caputi FF, Romualdi P, Domi A, Scuppa G, Candeletti S, Atkins A, Heilig M, Demopulos G, Gaitanaris G, Ciccocioppo R, Ubaldi M.

J Neurosci. 2019 Dec 4;39(49):9864-9875. doi: 10.1523/JNEUROSCI.1922-19.2019. Epub 2019 Nov 4.

PMID:
31685649
3.

Modulation of the Negative Affective Dimension of Pain: Focus on Selected Neuropeptidergic System Contributions.

Caputi FF, Rullo L, Stamatakos S, Candeletti S, Romualdi P.

Int J Mol Sci. 2019 Aug 17;20(16). pii: E4010. doi: 10.3390/ijms20164010. Review.

4.

Interplay between the Endogenous Opioid System and Proteasome Complex: Beyond Signaling.

Caputi FF, Rullo L, Stamatakos S, Candeletti S, Romualdi P.

Int J Mol Sci. 2019 Mar 21;20(6). pii: E1441. doi: 10.3390/ijms20061441. Review.

5.

Short-term withdrawal from repeated exposure to cocaine during adolescence modulates dynorphin mRNA levels and BDNF signaling in the rat nucleus accumbens.

Caputi FF, Caffino L, Candeletti S, Fumagalli F, Romualdi P.

Drug Alcohol Depend. 2019 Apr 1;197:127-133. doi: 10.1016/j.drugalcdep.2019.01.006. Epub 2019 Feb 13.

6.

Regulation of the Genes Encoding the ppN/OFQ and NOP Receptor.

Caputi FF, Romualdi P, Candeletti S.

Handb Exp Pharmacol. 2019;254:141-162. doi: 10.1007/164_2018_196.

PMID:
30689088
7.

Tapentadol: an analgesic that differs from classic opioids due to its noradrenergic mechanism of action.

Caputi FF, Nicora M, Simeone R, Candeletti S, Romualdi P.

Minerva Med. 2019 Feb;110(1):62-78. doi: 10.23736/S0026-4806.18.05909-8. Review.

PMID:
30667206
8.

Evidence of a PPARγ-mediated mechanism in the ability of Withania somnifera to attenuate tolerance to the antinociceptive effects of morphine.

Caputi FF, Rullo L, Acquas E, Ciccocioppo R, Candeletti S, Romualdi P.

Pharmacol Res. 2019 Jan;139:422-430. doi: 10.1016/j.phrs.2018.11.033. Epub 2018 Nov 29.

PMID:
30503841
9.

Dynorphinergic system alterations in the corticostriatal circuitry of neuropathic mice support its role in the negative affective component of pain.

Palmisano M, Caputi FF, Mercatelli D, Romualdi P, Candeletti S.

Genes Brain Behav. 2019 Jul;18(6):e12467. doi: 10.1111/gbb.12467. Epub 2018 Mar 15.

PMID:
29430855
10.

The standardized Withania somnifera Dunal root extract alters basal and morphine-induced opioid receptor gene expression changes in neuroblastoma cells.

Caputi FF, Acquas E, Kasture S, Ruiu S, Candeletti S, Romualdi P.

BMC Complement Altern Med. 2018 Jan 10;18(1):9. doi: 10.1186/s12906-017-2065-9.

11.

Mystic Acetaldehyde: The Never-Ending Story on Alcoholism.

Peana AT, Sánchez-Catalán MJ, Hipólito L, Rosas M, Porru S, Bennardini F, Romualdi P, Caputi FF, Candeletti S, Polache A, Granero L, Acquas E.

Front Behav Neurosci. 2017 May 11;11:81. doi: 10.3389/fnbeh.2017.00081. eCollection 2017. Review.

12.

Transcriptional and epigenetic phenomena in peripheral blood cells of monozygotic twins discordant for alzheimer's disease, a case report.

D'Addario C, Candia SB, Arosio B, Di Bartolomeo M, Abbate C, Casè A, Candeletti S, Romualdi P, Damanti S, Maccarrone M, Bergamaschini L, Mari D.

J Neurol Sci. 2017 Jan 15;372:211-216. doi: 10.1016/j.jns.2016.11.052. Epub 2016 Nov 24.

PMID:
28017215
13.

N/OFQ system in brain areas of nerve-injured mice: its role in different aspects of neuropathic pain.

Palmisano M, Mercatelli D, Caputi FF, Carretta D, Romualdi P, Candeletti S.

Genes Brain Behav. 2017 Jun;16(5):537-545. doi: 10.1111/gbb.12365. Epub 2017 Jan 10.

14.

Opioid gene expression changes and post-translational histone modifications at promoter regions in the rat nucleus accumbens after acute and repeated 3,4-methylenedioxy-methamphetamine (MDMA) exposure.

Caputi FF, Palmisano M, Carboni L, Candeletti S, Romualdi P.

Pharmacol Res. 2016 Dec;114:209-218. doi: 10.1016/j.phrs.2016.10.023. Epub 2016 Oct 29.

PMID:
27989838
15.

Alghedon Fentanyl Transdermal System.

Romualdi P, Santi P, Candeletti S.

Minerva Med. 2017 Apr;108(2):169-175. doi: 10.23736/S0026-4806.16.04930-2. Epub 2016 Nov 25. Review.

PMID:
27886163
16.

Fentanyl citrate sublingual formulation (Vellofent®) for quick BTcP hindering.

Romualdi P, Candeletti S.

Minerva Med. 2016 Apr;107(2):114-22. Review.

PMID:
27064584
17.

Cocaine and ethanol target 26S proteasome activity and gene expression in neuroblastoma cells.

Caputi FF, Carboni L, Mazza D, Candeletti S, Romualdi P.

Drug Alcohol Depend. 2016 Apr 1;161:265-75. doi: 10.1016/j.drugalcdep.2016.02.012. Epub 2016 Feb 16.

PMID:
26922280
18.

Treatment with the neurotoxic Aβ (25-35) peptide modulates the expression of neuroprotective factors Pin1, Sirtuin 1, and brain-derived neurotrophic factor in SH-SY5Y human neuroblastoma cells.

Lattanzio F, Carboni L, Carretta D, Candeletti S, Romualdi P.

Exp Toxicol Pathol. 2016 May;68(5):271-6. doi: 10.1016/j.etp.2016.02.001. Epub 2016 Feb 22.

PMID:
26915812
19.

Proteasome subunit and opioid receptor gene expression down-regulation induced by paraquat and maneb in human neuroblastoma SH-SY5Y cells.

Caputi FF, Carretta D, Lattanzio F, Palmisano M, Candeletti S, Romualdi P.

Environ Toxicol Pharmacol. 2015 Nov;40(3):895-900. doi: 10.1016/j.etap.2015.09.019. Epub 2015 Oct 3.

PMID:
26498265
20.

Effects of acute ethanol exposure on class I HDACs family enzymes in wild-type and BDNF(+/-) mice.

Caputi FF, Palmisano M, D'Addario C, Candeletti S, Romualdi P.

Drug Alcohol Depend. 2015 Oct 1;155:68-75. doi: 10.1016/j.drugalcdep.2015.08.015. Epub 2015 Aug 28.

PMID:
26361715
21.

Peripheral leukocyte expression of the potential biomarker proteins Bdnf, Sirt1, and Psen1 is not regulated by promoter methylation in Alzheimer's disease patients.

Carboni L, Lattanzio F, Candeletti S, Porcellini E, Raschi E, Licastro F, Romualdi P.

Neurosci Lett. 2015 Sep 25;605:44-8. doi: 10.1016/j.neulet.2015.08.012. Epub 2015 Aug 11.

PMID:
26275347
22.

A new potent analgesic agent with reduced liability to produce morphine tolerance.

Kiraly K, Caputi FF, Hanuska A, Kató E, Balogh M, Köles L, Palmisano M, Riba P, Hosztafi S, Romualdi P, Candeletti S, Ferdinandy P, Fürst S, Al-Khrasani M.

Brain Res Bull. 2015 Aug;117:32-8. doi: 10.1016/j.brainresbull.2015.07.005. Epub 2015 Jul 30.

PMID:
26235542
23.

Opioid receptor gene expression in human neuroblastoma SH-SY5Y cells following tapentadol exposure.

Caputi FF, Carretta D, Tzschentke TM, Candeletti S, Romualdi P.

J Mol Neurosci. 2014 Aug;53(4):669-76. doi: 10.1007/s12031-014-0235-5. Epub 2014 Feb 4.

PMID:
24488603
24.

Combined exposure to agriculture pesticides, paraquat and maneb, induces alterations in the N/OFQ-NOPr and PDYN/KOPr systems in rats: Relevance to sporadic Parkinson's disease.

Bastías-Candia S, Di Benedetto M, D'Addario C, Candeletti S, Romualdi P.

Environ Toxicol. 2015 May-Jun;30(6):656-63. doi: 10.1002/tox.21943. Epub 2013 Dec 23.

PMID:
24376148
25.

Dynorphin/KOP and nociceptin/NOP gene expression and epigenetic changes by cocaine in rat striatum and nucleus accumbens.

Caputi FF, Di Benedetto M, Carretta D, Bastias del Carmen Candia S, D'Addario C, Cavina C, Candeletti S, Romualdi P.

Prog Neuropsychopharmacol Biol Psychiatry. 2014 Mar 3;49:36-46. doi: 10.1016/j.pnpbp.2013.10.016. Epub 2013 Nov 1.

PMID:
24184686
26.

Human apolipoprotein E4 modulates the expression of Pin1, Sirtuin 1, and Presenilin 1 in brain regions of targeted replacement apoE mice.

Lattanzio F, Carboni L, Carretta D, Rimondini R, Candeletti S, Romualdi P.

Neuroscience. 2014 Jan 3;256:360-9. doi: 10.1016/j.neuroscience.2013.10.017. Epub 2013 Oct 23.

PMID:
24161275
27.

Morphine and fentanyl differently affect MOP and NOP gene expression in human neuroblastoma SH-SY5Y cells.

Caputi FF, Lattanzio F, Carretta D, Mercatelli D, Candeletti S, Romualdi P.

J Mol Neurosci. 2013 Oct;51(2):532-8. doi: 10.1007/s12031-013-0019-3. Epub 2013 May 29.

PMID:
23715695
28.

Ethanol induces epigenetic modulation of prodynorphin and pronociceptin gene expression in the rat amygdala complex.

D'Addario C, Caputi FF, Ekström TJ, Di Benedetto M, Maccarrone M, Romualdi P, Candeletti S.

J Mol Neurosci. 2013 Feb;49(2):312-9. doi: 10.1007/s12031-012-9829-y. Epub 2012 Jun 10.

PMID:
22684622
29.

Selective DNA methylation of BDNF promoter in bipolar disorder: differences among patients with BDI and BDII.

D'Addario C, Dell'Osso B, Palazzo MC, Benatti B, Lietti L, Cattaneo E, Galimberti D, Fenoglio C, Cortini F, Scarpini E, Arosio B, Di Francesco A, Di Benedetto M, Romualdi P, Candeletti S, Mari D, Bergamaschini L, Bresolin N, Maccarrone M, Altamura AC.

Neuropsychopharmacology. 2012 Jun;37(7):1647-55. doi: 10.1038/npp.2012.10. Epub 2012 Feb 22.

30.

Pin1 contribution to Alzheimer's disease: transcriptional and epigenetic mechanisms in patients with late-onset Alzheimer's disease.

Arosio B, Bulbarelli A, Bastias Candia S, Lonati E, Mastronardi L, Romualdi P, Candeletti S, Gussago C, Galimberti D, Scarpini E, Dell'Osso B, Altamura C, MacCarrone M, Bergamaschini L, D'Addario C, Mari D.

Neurodegener Dis. 2012;10(1-4):207-11. doi: 10.1159/000333799. Epub 2012 Jan 17.

PMID:
22261503
31.

∆(9)-Tetrahydrocannabinol decreases NOP receptor density and mRNA levels in human SH-SY5Y cells.

Cannarsa R, Carretta D, Lattanzio F, Candeletti S, Romualdi P.

J Mol Neurosci. 2012 Feb;46(2):285-92. doi: 10.1007/s12031-011-9552-0. Epub 2011 May 21.

PMID:
21603976
32.

Different alcohol exposures induce selective alterations on the expression of dynorphin and nociceptin systems related genes in rat brain.

D'Addario C, Caputi FF, Rimondini R, Gandolfi O, Del Borrello E, Candeletti S, Romualdi P.

Addict Biol. 2013 May;18(3):425-33. doi: 10.1111/j.1369-1600.2011.00326.x. Epub 2011 Apr 20.

PMID:
21507157
33.

Regulation of opioid gene expression in the rat brainstem by 3,4-methylenedioxymethamphetamine (MDMA): role of serotonin and involvement of CREB and ERK cascade.

Di Benedetto M, Bastías Candia Sdel C, D'Addario C, Porticella EE, Cavina C, Candeletti S, Romualdi P.

Naunyn Schmiedebergs Arch Pharmacol. 2011 Feb;383(2):169-78. doi: 10.1007/s00210-010-0587-5. Epub 2010 Dec 23.

PMID:
21181116
34.

Ethanol and acetaldehyde exposure induces specific epigenetic modifications in the prodynorphin gene promoter in a human neuroblastoma cell line.

D'Addario C, Johansson S, Candeletti S, Romualdi P, Ögren SO, Terenius L, Ekström TJ.

FASEB J. 2011 Mar;25(3):1069-75. doi: 10.1096/fj.10-168534. Epub 2010 Nov 24.

PMID:
21106935
35.

Acute and chronic cannabinoid extracts administration affects motor function in a CREAE model of multiple sclerosis.

Buccellato E, Carretta D, Utan A, Cavina C, Speroni E, Grassi G, Candeletti S, Romualdi P.

J Ethnopharmacol. 2011 Feb 16;133(3):1033-8. doi: 10.1016/j.jep.2010.11.035. Epub 2010 Nov 19.

PMID:
21094240
36.

Brain interstitial nociceptin/orphanin FQ levels are elevated in Parkinson's disease.

Marti M, Sarubbo S, Latini F, Cavallo M, Eleopra R, Biguzzi S, Lettieri C, Conti C, Simonato M, Zucchini S, Quatrale R, Sensi M, Candeletti S, Romualdi P, Morari M.

Mov Disord. 2010 Aug 15;25(11):1723-32. doi: 10.1002/mds.23271.

PMID:
20589874
37.

Nociceptin modulates bronchoconstriction induced by sensory nerve activation in mouse lung.

D'Agostino B, Orlotti D, Calò G, Sullo N, Russo M, Guerrini R, De Nardo M, Mazzeo F, Candeletti S, Rossi F.

Am J Respir Cell Mol Biol. 2010 Feb;42(2):250-4. doi: 10.1165/rcmb.2008-0488OC. Epub 2009 May 15.

PMID:
19448152
38.

Alterations of N/OFQ and NOP receptor gene expression in the substantia nigra and caudate putamen of MPP+ and 6-OHDA lesioned rats.

Di Benedetto M, Cavina C, D'Addario C, Leoni G, Candeletti S, Cox BM, Romualdi P.

Neuropharmacology. 2009 Mar;56(4):761-7. doi: 10.1016/j.neuropharm.2008.12.009.

39.

Kainic acid down-regulates NOP receptor density and gene expression in human neuroblastoma SH-SY5Y cells.

Cannarsa R, Landuzzi D, Cavina C, Candeletti S, Romualdi P.

J Mol Neurosci. 2008 Jun;35(2):171-7. doi: 10.1007/s12031-008-9038-x. Epub 2008 Feb 20.

PMID:
18286384
40.

Chronic delta 9-tetrahydrocannabinol during adolescence provokes sex-dependent changes in the emotional profile in adult rats: behavioral and biochemical correlates.

Rubino T, Vigano' D, Realini N, Guidali C, Braida D, Capurro V, Castiglioni C, Cherubino F, Romualdi P, Candeletti S, Sala M, Parolaro D.

Neuropsychopharmacology. 2008 Oct;33(11):2760-71. doi: 10.1038/sj.npp.1301664. Epub 2008 Jan 2.

41.

The kappa-opioid receptor agonist U-69593 prevents cocaine-induced phosphorylation of DARPP-32 at Thr(34) in the rat brain.

D'Addario C, Di Benedetto M, Candeletti S, Romualdi P.

Brain Res Bull. 2007 Jun 15;73(1-3):34-9. Epub 2007 Feb 20.

PMID:
17499634
42.

Chronic cocaine produces decreases in N/OFQ peptide levels in select rat brain regions.

Romualdi P, Di Benedetto M, D'Addario C, Collins SL, Wade D, Candeletti S, Izenwasser S.

J Mol Neurosci. 2007;31(2):159-64.

PMID:
17478889
43.

Effects of prolonged treatment with the opiate tramadol on prodynorphin gene expression in rat CNS.

Candeletti S, Lopetuso G, Cannarsa R, Cavina C, Romualdi P.

J Mol Neurosci. 2006;30(3):341-7.

PMID:
17401159
44.

Alterations of CREB and DARPP-32 phosphorylation following cocaine and monoaminergic uptake inhibitors.

Di Benedetto M, D'Addario C, Candeletti S, Romualdi P.

Brain Res. 2007 Jan 12;1128(1):33-9. Epub 2006 Nov 27.

PMID:
17125745
45.

Role of serotonin in the regulation of the dynorphinergic system by a kappa-opioid agonist and cocaine treatment in rat CNS.

D'Addario C, Di Benedetto M, Izenwasser S, Candeletti S, Romualdi P.

Neuroscience. 2007 Jan 5;144(1):157-64. Epub 2006 Oct 19.

PMID:
17055175
46.

Nociceptin levels in the cerebrospinal fluid of chronic pain patients with or without intrathecal administration of morphine.

Raffaeli W, Samolsky Dekel BG, Landuzzi D, Caminiti A, Righetti D, Balestri M, Montanari F, Romualdi P, Candeletti S.

J Pain Symptom Manage. 2006 Oct;32(4):372-7.

47.

Alterations in prodynorphin gene expression and dynorphin levels in different brain regions after chronic administration of 14-methoxymetopon and oxycodone-6-oxime.

Király KP, Riba P, D'Addario C, Di Benedetto M, Landuzzi D, Candeletti S, Romualdi P, Furst S.

Brain Res Bull. 2006 Jul 31;70(3):233-9. Epub 2006 Jun 2.

PMID:
16861108
48.

Chronic and acute effects of 3,4-methylenedioxy-N-methylamphetamine ('Ecstasy') administration on the dynorphinergic system in the rat brain.

Di Benedetto M, D'addario C, Candeletti S, Romualdi P.

Neuroscience. 2006;137(1):187-96. Epub 2005 Nov 10.

PMID:
16289352
49.

Blockade of nociceptin/orphanin FQ transmission attenuates symptoms and neurodegeneration associated with Parkinson's disease.

Marti M, Mela F, Fantin M, Zucchini S, Brown JM, Witta J, Di Benedetto M, Buzas B, Reinscheid RK, Salvadori S, Guerrini R, Romualdi P, Candeletti S, Simonato M, Cox BM, Morari M.

J Neurosci. 2005 Oct 19;25(42):9591-601.

50.

Nociceptin/orphanin FQ prevents the antinociceptive action of paracetamol on the rat hot plate test.

Sandrini M, Vitale G, Pini LA, Lopetuso G, Romualdi P, Candeletti S.

Eur J Pharmacol. 2005 Jan 10;507(1-3):43-8. Epub 2004 Dec 15.

PMID:
15659293

Supplemental Content

Loading ...
Support Center