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Human IgA binds a diverse array of commensal bacteria.

Sterlin D, Fadlallah J, Adams O, Fieschi C, Parizot C, Dorgham K, Rajkumar A, Autaa G, El-Kafsi H, Charuel JL, Juste C, Jönsson F, Candela T, Wardemann H, Aubry A, Capito C, Brisson H, Tresallet C, Cummings RD, Larsen M, Yssel H, von Gunten S, Gorochov G.

J Exp Med. 2020 Mar 2;217(3). pii: e20181635. doi: 10.1084/jem.20181635.


The Ser/Thr Kinase PrkC Participates in Cell Wall Homeostasis and Antimicrobial Resistance in Clostridium difficile.

Cuenot E, Garcia-Garcia T, Douche T, Gorgette O, Courtin P, Denis-Quanquin S, Hoys S, Tremblay YDN, Matondo M, Chapot-Chartier MP, Janoir C, Dupuy B, Candela T, Martin-Verstraete I.

Infect Immun. 2019 Jul 23;87(8). pii: e00005-19. doi: 10.1128/IAI.00005-19. Print 2019 Aug.


CalY is a major virulence factor and a biofilm matrix protein.

Candela T, Fagerlund A, Buisson C, Gilois N, Kolstø AB, Økstad OA, Aymerich S, Nielsen-Leroux C, Lereclus D, Gohar M.

Mol Microbiol. 2019 Jun;111(6):1416-1429. doi: 10.1111/mmi.14184. Epub 2019 Apr 15.


N-Deacetylases required for muramic-δ-lactam production are involved in Clostridium difficile sporulation, germination, and heat resistance.

Coullon H, Rifflet A, Wheeler R, Janoir C, Boneca IG, Candela T.

J Biol Chem. 2018 Nov 23;293(47):18040-18054. doi: 10.1074/jbc.RA118.004273. Epub 2018 Sep 28.


Clostridium difficile forms variable biofilms on abiotic surface.

Pantaléon V, Monot M, Eckert C, Hoys S, Collignon A, Janoir C, Candela T.

Anaerobe. 2018 Oct;53:34-37. doi: 10.1016/j.anaerobe.2018.05.006. Epub 2018 May 18. Review.


How earthquakes are induced.

Candela T, Wassing B, Ter Heege J, Buijze L.

Science. 2018 May 11;360(6389):598-600. doi: 10.1126/science.aat2776. No abstract available.


Surfaceome and Proteosurfaceome in Parietal Monoderm Bacteria: Focus on Protein Cell-Surface Display.

Desvaux M, Candela T, Serror P.

Front Microbiol. 2018 Feb 14;9:100. doi: 10.3389/fmicb.2018.00100. eCollection 2018. Review.


A cfr-like gene cfr(C) conferring linezolid resistance is common in Clostridium difficile.

Candela T, Marvaud JC, Nguyen TK, Lambert T.

Int J Antimicrob Agents. 2017 Sep;50(3):496-500. doi: 10.1016/j.ijantimicag.2017.03.013. Epub 2017 Jun 27.


The Clostridium difficile Protease Cwp84 Modulates both Biofilm Formation and Cell-Surface Properties.

Pantaléon V, Soavelomandroso AP, Bouttier S, Briandet R, Roxas B, Chu M, Collignon A, Janoir C, Vedantam G, Candela T.

PLoS One. 2015 Apr 29;10(4):e0124971. doi: 10.1371/journal.pone.0124971. eCollection 2015.


Clostridium difficile surface proteins are anchored to the cell wall using CWB2 motifs that recognise the anionic polymer PSII.

Willing SE, Candela T, Shaw HA, Seager Z, Mesnage S, Fagan RP, Fairweather NF.

Mol Microbiol. 2015 May;96(3):596-608. doi: 10.1111/mmi.12958. Epub 2015 Mar 6.


Biofilms of Clostridium species.

Pantaléon V, Bouttier S, Soavelomandroso AP, Janoir C, Candela T.

Anaerobe. 2014 Dec;30:193-8. doi: 10.1016/j.anaerobe.2014.09.010. Epub 2014 Sep 19. Review.


N-acetylglucosamine deacetylases modulate the anchoring of the gamma-glutamyl capsule to the cell wall of Bacillus anthracis.

Candela T, Balomenou S, Aucher W, Bouriotis V, Simore JP, Fouet A, Boneca IG.

Microb Drug Resist. 2014 Jun;20(3):222-30. doi: 10.1089/mdr.2014.0063. Epub 2014 May 15.


The functional vanGCd cluster of Clostridium difficile does not confer vancomycin resistance.

Ammam F, Meziane-Cherif D, Mengin-Lecreulx D, Blanot D, Patin D, Boneca IG, Courvalin P, Lambert T, Candela T.

Mol Microbiol. 2013 Aug;89(4):612-25. doi: 10.1111/mmi.12299. Epub 2013 Jul 12.


Cell-wall preparation containing poly-γ-D-glutamate covalently linked to peptidoglycan, a straightforward extractable molecule, protects mice against experimental anthrax infection.

Candela T, Dumetz F, Tosi-Couture E, Mock M, Goossens PL, Fouet A.

Vaccine. 2012 Dec 17;31(1):171-5. doi: 10.1016/j.vaccine.2012.10.071. Epub 2012 Nov 1.


Localization of the Clostridium difficile cysteine protease Cwp84 and insights into its maturation process.

ChapetónMontes D, Candela T, Collignon A, Janoir C.

J Bacteriol. 2011 Oct;193(19):5314-21. doi: 10.1128/JB.00326-11. Epub 2011 Jul 22.


Environmental and biofilm-dependent changes in a Bacillus cereus secondary cell wall polysaccharide.

Candela T, Maes E, Garénaux E, Rombouts Y, Krzewinski F, Gohar M, Guérardel Y.

J Biol Chem. 2011 Sep 9;286(36):31250-62. doi: 10.1074/jbc.M111.249821. Epub 2011 Jul 22.


Encapsulated Bacillus anthracis interacts closely with liver endothelium.

Piris-Gimenez A, Corre JP, Jouvion G, Candela T, Khun H, Goossens PL.

J Infect Dis. 2009 Nov 1;200(9):1381-9. doi: 10.1086/644506.


Fusobacterium nucleatum, the first Gram-negative bacterium demonstrated to produce polyglutamate.

Candela T, Moya M, Haustant M, Fouet A.

Can J Microbiol. 2009 May;55(5):627-32. doi: 10.1139/w09-003.


Edema toxin impairs anthracidal phospholipase A2 expression by alveolar macrophages.

Raymond B, Leduc D, Ravaux L, Le Goffic R, Candela T, Raymondjean M, Goossens PL, Touqui L.

PLoS Pathog. 2007 Dec;3(12):e187.


Role of the wbt locus of Francisella tularensis in lipopolysaccharide O-antigen biogenesis and pathogenicity.

Raynaud C, Meibom KL, Lety MA, Dubail I, Candela T, Frapy E, Charbit A.

Infect Immun. 2007 Jan;75(1):536-41. Epub 2006 Oct 9.

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