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Items: 1 to 50 of 143


Nucleoside-modified mRNA encoding HSV-2 glycoproteins C, D, and E prevents clinical and subclinical genital herpes.

Awasthi S, Hook LM, Pardi N, Wang F, Myles A, Cancro MP, Cohen GH, Weissman D, Friedman HM.

Sci Immunol. 2019 Sep 20;4(39). pii: eaaw7083. doi: 10.1126/sciimmunol.aaw7083.


Molecular pattern recognition in peripheral B cell tolerance: lessons from age-associated B cells.

Johnson JL, Scholz JL, Marshak-Rothstein A, Cancro MP.

Curr Opin Immunol. 2019 Aug 22;61:33-38. doi: 10.1016/j.coi.2019.07.008. [Epub ahead of print] Review.


The E3 ubiquitin ligase Itch restricts antigen-driven B cell responses.

Moser EK, Roof J, Dybas JM, Spruce LA, Seeholzer SH, Cancro MP, Oliver PM.

J Exp Med. 2019 Sep 2;216(9):2170-2183. doi: 10.1084/jem.20181953. Epub 2019 Jul 16.


IgM Plasma Cells Reside in Healthy Skin and Accumulate with Chronic Inflammation.

Wilson RP, McGettigan SE, Dang VD, Kumar A, Cancro MP, Nikbakht N, Stohl W, Debes GF.

J Invest Dermatol. 2019 May 30. pii: S0022-202X(19)31623-9. doi: 10.1016/j.jid.2019.05.009. [Epub ahead of print]


T-bet+ memory B cells: Generation, function, and fate.

Knox JJ, Myles A, Cancro MP.

Immunol Rev. 2019 Mar;288(1):149-160. doi: 10.1111/imr.12736. Review.


T-bet+ B cells: A common denominator in protective and autoreactive antibody responses?

Myles A, Sanz I, Cancro MP.

Curr Opin Immunol. 2019 Apr;57:40-45. doi: 10.1016/j.coi.2019.01.002. Epub 2019 Feb 19. Review.


TACI expression and plasma cell differentiation are impaired in the absence of functional IκBNS.

Khoenkhoen S, Erikson E, Ádori M, Stark JM, Scholz JL, Cancro MP, Pedersen GK, Karlsson Hedestam GB.

Immunol Cell Biol. 2019 May;97(5):485-497. doi: 10.1111/imcb.12228. Epub 2019 Jan 30.


Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses.

Pardi N, Hogan MJ, Naradikian MS, Parkhouse K, Cain DW, Jones L, Moody MA, Verkerke HP, Myles A, Willis E, LaBranche CC, Montefiori DC, Lobby JL, Saunders KO, Liao HX, Korber BT, Sutherland LL, Scearce RM, Hraber PT, Tombácz I, Muramatsu H, Ni H, Balikov DA, Li C, Mui BL, Tam YK, Krammer F, Karikó K, Polacino P, Eisenlohr LC, Madden TD, Hope MJ, Lewis MG, Lee KK, Hu SL, Hensley SE, Cancro MP, Haynes BF, Weissman D.

J Exp Med. 2018 Jun 4;215(6):1571-1588. doi: 10.1084/jem.20171450. Epub 2018 May 8.


IL-21 drives expansion and plasma cell differentiation of autoreactive CD11chiT-bet+ B cells in SLE.

Wang S, Wang J, Kumar V, Karnell JL, Naiman B, Gross PS, Rahman S, Zerrouki K, Hanna R, Morehouse C, Holoweckyj N, Liu H; Autoimmunity Molecular Medicine Team, Manna Z, Goldbach-Mansky R, Hasni S, Siegel R, Sanjuan M, Streicher K, Cancro MP, Kolbeck R, Ettinger R.

Nat Commun. 2018 May 1;9(1):1758. doi: 10.1038/s41467-018-03750-7.


The Reign of Antibodies: A Celebration of and Tribute to Michael Potter and His Homogeneous Immunoglobulin Workshops.

Gearhart PJ, Mock BA, Casellas R, Cancro MP.

J Immunol. 2018 Jan 1;200(1):23-26. doi: 10.4049/jimmunol.1701516. No abstract available.


Expanding roles for the Tbet+ B cell subset in health and disease.

Cancro MP.

Cell Immunol. 2017 Nov;321:1-2. doi: 10.1016/j.cellimm.2017.10.004. Epub 2017 Oct 14. No abstract available.


Signals that drive T-bet expression in B cells.

Myles A, Gearhart PJ, Cancro MP.

Cell Immunol. 2017 Nov;321:3-7. doi: 10.1016/j.cellimm.2017.09.004. Epub 2017 Sep 11.


Editorial: The nose knows.

Cancro MP, Allman DM.

J Leukoc Biol. 2017 Sep;102(3):569-571. doi: 10.1189/jlb.3CE0517-204R. No abstract available.


A TLR9-dependent checkpoint governs B cell responses to DNA-containing antigens.

Sindhava VJ, Oropallo MA, Moody K, Naradikian M, Higdon LE, Zhou L, Myles A, Green N, Nündel K, Stohl W, Schmidt AM, Cao W, Dorta-Estremera S, Kambayashi T, Marshak-Rothstein A, Cancro MP.

J Clin Invest. 2017 May 1;127(5):1651-1663. doi: 10.1172/JCI89931. Epub 2017 Mar 27.


T Regulatory Cells Support Plasma Cell Populations in the Bone Marrow.

Glatman Zaretsky A, Konradt C, Dépis F, Wing JB, Goenka R, Atria DG, Silver JS, Cho S, Wolf AI, Quinn WJ, Engiles JB, Brown DC, Beiting D, Erikson J, Allman D, Cancro MP, Sakaguchi S, Lu LF, Benoist CO, Hunter CA.

Cell Rep. 2017 Feb 21;18(8):1906-1916. doi: 10.1016/j.celrep.2017.01.067.


Age-Associated B Cells Express a Diverse Repertoire of VH and Vκ Genes with Somatic Hypermutation.

Russell Knode LM, Naradikian MS, Myles A, Scholz JL, Hao Y, Liu D, Ford ML, Tobias JW, Cancro MP, Gearhart PJ.

J Immunol. 2017 Mar 1;198(5):1921-1927. doi: 10.4049/jimmunol.1601106. Epub 2017 Jan 16.


The Old One-Two: Solving the Mystery of Cognate Help.

Cancro MP.

J Immunol. 2016 Dec 1;197(11):4193-4194. No abstract available.


Editorial: All that you can B: mirn23a regulates B versus myeloid fates.

Scholz JL, Allman D, Cancro MP.

J Leukoc Biol. 2016 Oct;100(4):642-644. No abstract available.


Cutting Edge: IL-4, IL-21, and IFN-γ Interact To Govern T-bet and CD11c Expression in TLR-Activated B Cells.

Naradikian MS, Myles A, Beiting DP, Roberts KJ, Dawson L, Herati RS, Bengsch B, Linderman SL, Stelekati E, Spolski R, Wherry EJ, Hunter C, Hensley SE, Leonard WJ, Cancro MP.

J Immunol. 2016 Aug 15;197(4):1023-8. doi: 10.4049/jimmunol.1600522. Epub 2016 Jul 18.


The NIK of time for B cells.

Myles A, Cancro MP.

Eur J Immunol. 2016 Mar;46(3):547-51. doi: 10.1002/eji.201646294.


Age-associated B cells: key mediators of both protective and autoreactive humoral responses.

Naradikian MS, Hao Y, Cancro MP.

Immunol Rev. 2016 Jan;269(1):118-29. doi: 10.1111/imr.12380. Review.


Nucleic Acid-Sensing Receptors: Rheostats of Autoimmunity and Autoinflammation.

Sharma S, Fitzgerald KA, Cancro MP, Marshak-Rothstein A.

J Immunol. 2015 Oct 15;195(8):3507-12. doi: 10.4049/jimmunol.1500964. Review.


B Cell-Intrinsic Expression of the HuR RNA-Binding Protein Is Required for the T Cell-Dependent Immune Response In Vivo.

DeMicco A, Naradikian MS, Sindhava VJ, Yoon JH, Gorospe M, Wertheim GB, Cancro MP, Bassing CH.

J Immunol. 2015 Oct 1;195(7):3449-62. doi: 10.4049/jimmunol.1500512. Epub 2015 Aug 28.


Age-Associated B Cells: A T-bet-Dependent Effector with Roles in Protective and Pathogenic Immunity.

Rubtsova K, Rubtsov AV, Cancro MP, Marrack P.

J Immunol. 2015 Sep 1;195(5):1933-7. doi: 10.4049/jimmunol.1501209. Review.


Caught Off Center: Rethinking the Requirements for Antibody Affinity Maturation.

Higdon LE, Cancro MP.

Immunity. 2015 Jul 21;43(1):5-6. doi: 10.1016/j.immuni.2015.07.002.


The B Cell-Stimulatory Cytokines BLyS and APRIL Are Elevated in Human Periodontitis and Are Required for B Cell-Dependent Bone Loss in Experimental Murine Periodontitis.

Abe T, AlSarhan M, Benakanakere MR, Maekawa T, Kinane DF, Cancro MP, Korostoff JM, Hajishengallis G.

J Immunol. 2015 Aug 15;195(4):1427-35. doi: 10.4049/jimmunol.1500496. Epub 2015 Jul 6.


Differential Development of Systemic Lupus Erythematosus in NZM 2328 Mice Deficient in Discrete Pairs of BAFF Receptors.

Jacob CO, Yu N, Sindhava V, Cancro MP, Pawar RD, Putterman C, Stohl W.

Arthritis Rheumatol. 2015 Sep;67(9):2523-35. doi: 10.1002/art.39210.


BAFF receptors and ligands create independent homeostatic niches for B cell subsets.

Naradikian MS, Perate AR, Cancro MP.

Curr Opin Immunol. 2015 Jun;34:126-9. doi: 10.1016/j.coi.2015.03.005. Epub 2015 Mar 30. Review.


Cell-intrinsic expression of TLR9 in autoreactive B cells constrains BCR/TLR7-dependent responses.

Nündel K, Green NM, Shaffer AL, Moody KL, Busto P, Eilat D, Miyake K, Oropallo MA, Cancro MP, Marshak-Rothstein A.

J Immunol. 2015 Mar 15;194(6):2504-12. doi: 10.4049/jimmunol.1402425. Epub 2015 Feb 13.


Editorial: Where's the B in NHP?

Scholz JL, Cancro MP.

J Leukoc Biol. 2015 Jan;97(1):5-7. doi: 10.1189/jlb.1CE0914-440R. No abstract available.


Spinal cord injury impacts B cell production, homeostasis, and activation.

Oropallo MA, Goenka R, Cancro MP.

Semin Immunol. 2014 Oct;26(5):421-7. doi: 10.1016/j.smim.2014.09.014. Epub 2014 Oct 25. Review.


Making new connections: the intersection of neurendocrine and immune regulation.

Dittel BN, Cancro MP.

Semin Immunol. 2014 Oct;26(5):355-6. doi: 10.1016/j.smim.2014.10.006. Epub 2014 Nov 6. No abstract available.


Ray D. Owen 1915-2014.

Cancro MP.

Nat Immunol. 2014 Dec;15(12):1091. doi: 10.1038/ni.3033. No abstract available.


APRIL mediates peritoneal B-1 cell homeostasis.

Sindhava VJ, Scholz JL, Stohl W, Cancro MP.

Immunol Lett. 2014 Aug;160(2):120-7. doi: 10.1016/j.imlet.2014.01.018. Epub 2014 Feb 7.


New roles for the BLyS/BAFF family in antigen-experienced B cell niches.

Goenka R, Scholz JL, Sindhava VJ, Cancro MP.

Cytokine Growth Factor Rev. 2014 Apr;25(2):107-13. doi: 10.1016/j.cytogfr.2014.01.001. Epub 2014 Jan 10. Review.


Memory B cells form in aged mice despite impaired affinity maturation and germinal center kinetics.

Goenka R, Scholz JL, Naradikian MS, Cancro MP.

Exp Gerontol. 2014 Jun;54:109-15. doi: 10.1016/j.exger.2013.12.013. Epub 2014 Jan 2.


Local BLyS production by T follicular cells mediates retention of high affinity B cells during affinity maturation.

Goenka R, Matthews AH, Zhang B, O'Neill PJ, Scholz JL, Migone TS, Leonard WJ, Stohl W, Hershberg U, Cancro MP.

J Exp Med. 2014 Jan 13;211(1):45-56. doi: 10.1084/jem.20130505. Epub 2013 Dec 23.


A comparative review of aging and B cell function in mice and humans.

Scholz JL, Diaz A, Riley RL, Cancro MP, Frasca D.

Curr Opin Immunol. 2013 Aug;25(4):504-10. doi: 10.1016/j.coi.2013.07.006. Epub 2013 Aug 6. Review.


The role of B lymphocyte stimulator in B cell biology: implications for the treatment of lupus.

Scholz JL, Oropallo MA, Sindhava V, Goenka R, Cancro MP.

Lupus. 2013 Apr;22(4):350-60. doi: 10.1177/0961203312469453. Review.


Roles for BLyS family members in meeting the distinct homeostatic demands of innate and adaptive B cells.

Sindhava VJ, Scholz JL, Cancro MP.

Front Immunol. 2013 Feb 25;4:37. doi: 10.3389/fimmu.2013.00037. eCollection 2013.


Development of systemic lupus erythematosus in NZM 2328 mice in the absence of any single BAFF receptor.

Jacob CO, Yu N, Guo S, Jacob N, Quinn WJ 3rd, Sindhava V, Cancro MP, Goilav B, Putterman C, Migone TS, Stohl W.

Arthritis Rheum. 2013 Apr;65(4):1043-54. doi: 10.1002/art.37846.


BLyS-mediated modulation of naive B cell subsets impacts HIV Env-induced antibody responses.

Dosenovic P, Soldemo M, Scholz JL, O'Dell S, Grasset EK, Pelletier N, Karlsson MC, Mascola JR, Wyatt RT, Cancro MP, Karlsson Hedestam GB.

J Immunol. 2012 Jun 15;188(12):6018-26. doi: 10.4049/jimmunol.1200466. Epub 2012 May 4.


B cell maintenance and function in aging.

Kogut I, Scholz JL, Cancro MP, Cambier JC.

Semin Immunol. 2012 Oct;24(5):342-9. doi: 10.1016/j.smim.2012.04.004. Epub 2012 May 4. Review.


Long-lived bone marrow plasma cells are induced early in response to T cell-independent or T cell-dependent antigens.

Bortnick A, Chernova I, Quinn WJ 3rd, Mugnier M, Cancro MP, Allman D.

J Immunol. 2012 Jun 1;188(11):5389-96. doi: 10.4049/jimmunol.1102808. Epub 2012 Apr 23.


Chronic spinal cord injury impairs primary antibody responses but spares existing humoral immunity in mice.

Oropallo MA, Held KS, Goenka R, Ahmad SA, O'Neill PJ, Steward O, Lane TE, Cancro MP.

J Immunol. 2012 Jun 1;188(11):5257-66. doi: 10.4049/jimmunol.1101934. Epub 2012 Apr 20.


New wine in old bottles: expanding roles for B cells in transplantation tolerance.

Naji A, Noorchashm H, Cancro MP.

Semin Immunol. 2012 Apr;24(2):75-6. doi: 10.1016/j.smim.2012.03.001. No abstract available.


Editorial: phagocytic B cells: déjà vu all over again?

Cancro MP.

J Leukoc Biol. 2012 Apr;91(4):519-21. doi: 10.1189/jlb.1111540. No abstract available.


Role of type I interferons in the activation of autoreactive B cells.

Kiefer K, Oropallo MA, Cancro MP, Marshak-Rothstein A.

Immunol Cell Biol. 2012 May;90(5):498-504. doi: 10.1038/icb.2012.10. Epub 2012 Mar 20. Review.


Resolve, revise, and relax: the 3 Rs of B cell repertoire adjustment.

Scholz JL, Cancro MP.

Immunol Lett. 2012 Mar 30;143(1):2-8. doi: 10.1016/j.imlet.2012.01.014. Epub 2012 Feb 6. Review.


Beyond transitional selection: New roles for BLyS in peripheral tolerance.

Oropallo MA, Kiefer K, Marshak-Rothstein A, Cancro MP.

Drug Dev Res. 2011 Dec;72(8):779-787.

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