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Fluid and hemodynamic management in hemodialysis patients: challenges and opportunities.

Canaud B, Chazot C, Koomans J, Collins A.

J Bras Nefrol. 2019 Oct 24. pii: S0101-28002019005032102. doi: 10.1590/2175-8239-JBN-2019-0135. [Epub ahead of print] English, Portuguese.


Endothelial dysfunction and low-grade inflammation in the transition to renal replacement therapy.

Gennip ACEV, Broers NJH, Meulen KJT, Canaud B, Christiaans MHL, Cornelis T, Gelens MACJ, Hermans MMH, Konings CJAM, Net JBV, Sande FMV, Schalkwijk CG, Stifft F, Wirtz JJJM, Kooman JP, Martens RJH.

PLoS One. 2019 Sep 13;14(9):e0222547. doi: 10.1371/journal.pone.0222547. eCollection 2019.


Is high-volume post-dilution haemodiafiltration associated with risk of fluid volume imbalance? A national multicentre cross-sectional cohort study.

Chazot C, Deleuze S, Fadel B, Hebibi H, Jean G, Levannier M, Puyoo O, Attaf D, Stuard S, Canaud B.

Nephrol Dial Transplant. 2019 Aug 29. pii: gfz141. doi: 10.1093/ndt/gfz141. [Epub ahead of print]


Relations of advanced glycation endproducts and dicarbonyls with endothelial dysfunction and low-grade inflammation in individuals with end-stage renal disease in the transition to renal replacement therapy: A cross-sectional observational study.

Martens RJH, Broers NJH, Canaud B, Christiaans MHL, Cornelis T, Gauly A, Hermans MMH, Konings CJAM, van der Sande FM, Scheijen JLJM, Stifft F, Wirtz JJJM, Kooman JP, Schalkwijk CG.

PLoS One. 2019 Aug 13;14(8):e0221058. doi: 10.1371/journal.pone.0221058. eCollection 2019.


Short-Term Effects of Branched-Chain Amino Acids-Enriched Dialysis Fluid on Branched-Chain Amino Acids Plasma Level and Mass Balance: A Randomized Cross-Over Study.

Deleaval P, Luaire B, Laffay P, Jambut-Cadon D, Stauss-Grabo M, Canaud B, Chazot C.

J Ren Nutr. 2019 May 8. pii: S1051-2276(19)30155-4. doi: 10.1053/j.jrn.2019.03.079. [Epub ahead of print]


Automated individualization of dialysate sodium concentration reduces intradialytic plasma sodium changes in hemodialysis.

Ságová M, Wojke R, Maierhofer A, Gross M, Canaud B, Gauly A.

Artif Organs. 2019 Oct;43(10):1002-1013. doi: 10.1111/aor.13463. Epub 2019 Apr 29.


The Authors Reply.

Ramos R, de Francisco ALM, Merello JI, Canaud B, Varas J, Stuard S, Pascual J, Aljama P P; Optimizing Results in Dialysis (ORD) group.

Kidney Int Rep. 2019 Jan 9;4(3):505-506. doi: 10.1016/j.ekir.2018.12.013. eCollection 2019 Mar. No abstract available.


Development of an Artificial Intelligence Model to Guide the Management of Blood Pressure, Fluid Volume, and Dialysis Dose in End-Stage Kidney Disease Patients: Proof of Concept and First Clinical Assessment.

Barbieri C, Cattinelli I, Neri L, Mari F, Ramos R, Brancaccio D, Canaud B, Stuard S.

Kidney Dis (Basel). 2019 Feb;5(1):28-33. doi: 10.1159/000493479. Epub 2018 Nov 7. Review.


Effects of high-volume online mixed-hemodiafiltration on anemia management in dialysis patients.

Pedrini LA, Zawada AM, Winter AC, Pham J, Klein G, Wolf M, Feuersenger A, Ruggiero P, Feliciani A, Barbieri C, Gauly A, Canaud B, Stuard S.

PLoS One. 2019 Feb 22;14(2):e0212795. doi: 10.1371/journal.pone.0212795. eCollection 2019.


Global prevalent use, trends and practices in haemodiafiltration.

Canaud B, Köhler K, Sichart JM, Möller S.

Nephrol Dial Transplant. 2019 Feb 14. pii: gfz005. doi: 10.1093/ndt/gfz005. [Epub ahead of print]


Chronic Kidney Disease: Exploring Value-Based Healthcare as a Potential Viable Solution.

Busink E, Canaud B, Schröder-Bäck P, Paulus ATG, Evers SMAA, Apel C, Bowry SK, Stopper A.

Blood Purif. 2019;47(1-3):156-165. doi: 10.1159/000496681. Epub 2019 Feb 1. Review.


Clinical outcomes of hemodialysis patients in a public-private partnership care framework in Italy: a retrospective cohort study.

Pedrini LA, Winter AC, Cerino F, Zawada AM, Garbelli M, Feuersenger A, Feliciani A, Ruggiero P, Civardi S, Amato C, Canaud B, Stuard S, Karch A, Gauly A.

BMC Nephrol. 2019 Feb 1;20(1):35. doi: 10.1186/s12882-019-1224-2.


Sodium and water handling during hemodialysis: new pathophysiologic insights and management approaches for improving outcomes in end-stage kidney disease.

Canaud B, Kooman J, Selby NM, Taal M, Francis S, Kopperschmidt P, Maierhofer A, Kotanko P, Titze J.

Kidney Int. 2019 Feb;95(2):296-309. doi: 10.1016/j.kint.2018.09.024. Review.


Increased Mortality Associated with Higher Pre-Dialysis Serum Sodium Variability: Results of the International MONitoring Dialysis Outcome Initiative.

Ye X, Kooman JP, van der Sande FM, Canaud B, Stuard S, Etter M, Xu X, Marelli C, Guinsburg A, Power A, Usvyat LA, Wang Y, Kotanko P, Raimann JG; for the MONDO Initiative.

Am J Nephrol. 2019;49(1):1-10. doi: 10.1159/000495354. Epub 2018 Dec 13.


A Cross-Sectional Study of Growth and Metabolic Bone Disease in a Pediatric Global Cohort Undergoing Chronic Hemodialysis.

Hussein R, Alvarez-Elías AC, Topping A, Raimann JG, Filler G, Yousif D, Kotanko P, Usvyat LA, Medeiros M, Pecoits-Filho R, Canaud B, Stuard S, Xiaoqi X, Etter M, Díaz-González de Ferris ME; MONDO Consortium.

J Pediatr. 2018 Nov;202:171-178.e3. doi: 10.1016/j.jpeds.2018.07.033. Epub 2018 Sep 26.


Zero Diffusive Sodium Balance in Hemodialysis Provided by an Algorithm-Based Electrolyte Balancing Controller: A Proof of Principle Clinical Study.

Kuhlmann U, Maierhofer A, Canaud B, Hoyer J, Gross M.

Artif Organs. 2019 Feb;43(2):150-158. doi: 10.1111/aor.13328. Epub 2018 Sep 27.


Detecting high-risk chronic kidney disease-mineral bone disorder phenotypes among patients on dialysis: a historical cohort study.

Neri L, Kreuzberg U, Bellocchio F, Brancaccio D, Barbieri C, Canaud B, Stuard S, Ketteler M.

Nephrol Dial Transplant. 2019 Apr 1;34(4):682-691. doi: 10.1093/ndt/gfy273.


Interactions Between Malnutrition, Inflammation, and Fluid Overload and Their Associations With Survival in Prevalent Hemodialysis Patients.

Dekker MJE, Konings C, Canaud B, van der Sande FM, Stuard S, Raimann JG, Öztürk E, Usvyat L, Kotanko P, Kooman JP.

J Ren Nutr. 2018 Nov;28(6):435-444. doi: 10.1053/j.jrn.2018.06.005. Epub 2018 Aug 23.


Lipid levels are inversely associated with infectious and all-cause mortality: international MONDO study results.

Kaysen GA, Ye X, Raimann JG, Wang Y, Topping A, Usvyat LA, Stuard S, Canaud B, van der Sande FM, Kooman JP, Kotanko P; Monitoring Dialysis Outcomes (MONDO) Initiative.

J Lipid Res. 2018 Aug;59(8):1519-1528. doi: 10.1194/jlr.P084277. Epub 2018 Jun 12.


CVD diamond detector with interdigitated electrode pattern for time-of-flight energy-loss measurements of low-energy ion bunches.

Cayzac W, Pomorski M, Blažević A, Canaud B, Deslandes D, Fariaut J, Gontier D, Lescoute E, Marmouget JG, Occelli F, Oudot G, Reverdin C, Sauvestre JE, Sollier A, Soullié G, Varignon C, Villette B.

Rev Sci Instrum. 2018 May;89(5):053301. doi: 10.1063/1.5019879.


Proton Pump Inhibitor Usage and the Risk of Mortality in Hemodialysis Patients.

de Francisco ALM, Varas J, Ramos R, Merello JI, Canaud B, Stuard S, Pascual J, Aljama P; Optimizing Results in Dialysis (ORD) group.

Kidney Int Rep. 2017 Nov 10;3(2):374-384. doi: 10.1016/j.ekir.2017.11.001. eCollection 2018 Mar.


Pre-dialysis fluid status, pre-dialysis systolic blood pressure and outcome in prevalent haemodialysis patients: results of an international cohort study on behalf of the MONDO initiative.

Dekker M, Konings C, Canaud B, Carioni P, Guinsburg A, Madero M, van der Net J, Raimann J, van der Sande F, Stuard S, Usvyat L, Wang Y, Xu X, Kotanko P, Kooman J.

Nephrol Dial Transplant. 2018 Nov 1;33(11):2027-2034. doi: 10.1093/ndt/gfy095.


Greater fluid overload and lower interdialytic weight gain are independently associated with mortality in a large international hemodialysis population.

Hecking M, Moissl U, Genser B, Rayner H, Dasgupta I, Stuard S, Stopper A, Chazot C, Maddux FW, Canaud B, Port FK, Zoccali C, Wabel P.

Nephrol Dial Transplant. 2018 Oct 1;33(10):1832-1842. doi: 10.1093/ndt/gfy083.


Is There Not Sufficient Evidence to Show That Haemodiafiltration Is Superior to Conventional Haemodialysis in Treating End-Stage Kidney Disease Patients?

Canaud B, Busink E, Apel C, Bowry SK.

Blood Purif. 2018;46(1):7-11. doi: 10.1159/000487918. Epub 2018 Apr 12. No abstract available.


Health-related quality of life in end-stage renal disease patients: the effects of starting dialysis in the first year after the transition period.

Broers NJH, Martens RJH, Canaud B, Cornelis T, Dejagere T, Diederen NMP, Hermans MMH, Konings CJAM, Stifft F, Wirtz JJJM, Leunissen KML, van der Sande FM, Kooman JP.

Int Urol Nephrol. 2018 Jun;50(6):1131-1142. doi: 10.1007/s11255-018-1845-6. Epub 2018 Mar 26.


Regulatory Considerations for Hemodiafiltration in the United States.

Ward RA, Vienken J, Silverstein DM, Ash S, Canaud B; Kidney Health Initiative HDF Workgroup.

Clin J Am Soc Nephrol. 2018 Sep 7;13(9):1444-1449. doi: 10.2215/CJN.12641117. Epub 2018 Mar 6.


Hemodiafiltration to Address Unmet Medical Needs ESKD Patients.

Canaud B, Vienken J, Ash S, Ward RA; Kidney Health Initiative HDF Workgroup.

Clin J Am Soc Nephrol. 2018 Sep 7;13(9):1435-1443. doi: 10.2215/CJN.12631117. Epub 2018 Mar 6.


Association between Heights of Dialysis Patients and Outcomes: Results from a Retrospective Cohort Study of the International MONitoring Dialysis Outcomes (MONDO) Database Initiative.

Patel S, Topping A, Ye X, Zhang H, Canaud B, Carioni P, Marelli C, Guinsburg A, Power A, Duncan N, Kooman J, van der Sande F, Usvyat LA, Wang Y, Xu X, Kotanko P, Raimann JG; the MONDO Initiative.

Blood Purif. 2018;45(1-3):245-253. doi: 10.1159/000485162. Epub 2018 Jan 26.


[Aluminic intoxication in chronic hemodialysis. A diagnosis rarely evoked nowadays. Clinical case and review of the literature].

Seidowsky A, Dupuis E, Drueke T, Dard S, Massy ZA, Canaud B.

Nephrol Ther. 2018 Feb;14(1):35-41. doi: 10.1016/j.nephro.2017.04.002. Epub 2017 Nov 23. Review. French.


Increased mortality in haemodialysis patients administered high doses of erythropoiesis-stimulating agents: a propensity score-matched analysis.

Pérez-García R, Varas J, Cives A, Martín-Malo A, Aljama P, Ramos R, Pascual J, Stuard S, Canaud B, Merello JI; ORD group.

Nephrol Dial Transplant. 2018 Jan 1;33(1):187. doi: 10.1093/ndt/gfx315. No abstract available.


Hemodiafiltration Reduces All-Cause and Cardiovascular Mortality in Incident Hemodialysis Patients: A Propensity-Matched Cohort Study.

Maduell F, Varas J, Ramos R, Martin-Malo A, Pérez-Garcia R, Berdud I, Moreso F, Canaud B, Stuard S, Gauly A, Aljama P, Merello JI.

Am J Nephrol. 2017;46(4):288-297. doi: 10.1159/000481669. Epub 2017 Oct 17.


Increased mortality in haemodialysis patients administered high doses of erythropoiesis-stimulating agents: a propensity score-matched analysis.

Pérez-García R, Varas J, Cives A, Martín-Malo A, Aljama P, Ramos R, Pascual J, Stuard S, Canaud B, Merello JI; ORD group.

Nephrol Dial Transplant. 2018 Apr 1;33(4):690-699. doi: 10.1093/ndt/gfx269.


Relationships between iron dose, hospitalizations and mortality in incident haemodialysis patients: a propensity-score matched approach.

Varas J, Ramos R, Aljama P, Pérez-García R, Moreso F, Pinedo M, Ignacio Merello J, Stuard S, Canaud B, Martín-Malo A; ORD Group.

Nephrol Dial Transplant. 2018 Jan 1;33(1):160-170. doi: 10.1093/ndt/gfx209.


Warfarin in CKD patients with atrial fibrillation.

Brancaccio D, Neri L, Bellocchio F, Barbieri C, Amato C, Mari F, Canaud B, Stuard S.

Kidney Int. 2017 Sep;92(3):766-767. doi: 10.1016/j.kint.2017.06.005. No abstract available.


Physical Activity in End-Stage Renal Disease Patients: The Effects of Starting Dialysis in the First 6 Months after the Transition Period.

Broers NJH, Martens RJH, Cornelis T, van der Sande FM, Diederen NMP, Hermans MMH, Wirtz JJJM, Stifft F, Konings CJAM, Dejagere T, Canaud B, Wabel P, Leunissen KML, Kooman JP.

Nephron. 2017;137(1):47-56. doi: 10.1159/000476072. Epub 2017 Jun 8.


Dialysis Access as an Area of Improvement in Elderly Incident Hemodialysis Patients: Results from a Cohort Study from the International Monitoring Dialysis Outcomes Initiative.

Raimann JG, Barth C, Usvyat LA, Preciado P, Canaud B, Etter M, Xu X, Guinsburg A, Marelli C, Duncan N, Power A, van der Sande FM, Kooman JP, Thijssen S, Wang Y, Kotanko P; Monitoring Dialysis Outcomes (MONDO) Initiative.

Am J Nephrol. 2017;45(6):486-496. doi: 10.1159/000476003. Epub 2017 May 17.


[Online hemodiafiltration: Practical aspects, safety and efficacy].

Canaud B, Chénine L, Leray-Moraguès H, Patrier L, Rodriguez A, Gontier-Picard A, Moréna M.

Nephrol Ther. 2017 May;13(3):189-201. doi: 10.1016/j.nephro.2017.02.007. Epub 2017 May 5. French.


Cardiovascular outcome trials in patients with chronic kidney disease: challenges associated with selection of patients and endpoints.

Rossignol P, Agarwal R, Canaud B, Charney A, Chatellier G, Craig JC, Cushman WC, Gansevoort RT, Fellström B, Garza D, Guzman N, Holtkamp FA, London GM, Massy ZA, Mebazaa A, Mol PGM, Pfeffer MA, Rosenberg Y, Ruilope LM, Seltzer J, Shah AM, Shah S, Singh B, Stefánsson BV, Stockbridge N, Stough WG, Thygesen K, Walsh M, Wanner C, Warnock DG, Wilcox CS, Wittes J, Pitt B, Thompson A, Zannad F.

Eur Heart J. 2019 Mar 14;40(11):880-886. doi: 10.1093/eurheartj/ehx209.


Plasma PCSK9 concentrations during the course of nondiabetic chronic kidney disease: Relationship with glomerular filtration rate and lipid metabolism.

Morena M, Le May C, Chenine L, Arnaud L, Dupuy AM, Pichelin M, Leray-Moragues H, Chalabi L, Canaud B, Cristol JP, Cariou B.

J Clin Lipidol. 2017 Jan - Feb;11(1):87-93. doi: 10.1016/j.jacl.2016.10.005. Epub 2016 Oct 15.


The importance of considering competing treatment affecting prognosis in the evaluation of therapy in trials: the example of renal transplantation in hemodialysis trials.

Hazelbag CM, Peters SAE, Blankestijn PJ, Bots ML, Canaud B, Davenport A, Grooteman MPC, Kircelli F, Locatelli F, Maduell F, Morena M, Nubé MJ, Ok E, Torres F, Hoes AW, Groenwold RHH; HDF Pooling Project investigators.

Nephrol Dial Transplant. 2017 Apr 1;32(suppl_2):ii31-ii39. doi: 10.1093/ndt/gfw458.


Treatment tolerance and patient-reported outcomes favor online hemodiafiltration compared to high-flux hemodialysis in the elderly.

Morena M, Jaussent A, Chalabi L, Leray-Moragues H, Chenine L, Debure A, Thibaudin D, Azzouz L, Patrier L, Maurice F, Nicoud P, Durand C, Seigneuric B, Dupuy AM, Picot MC, Cristol JP, Canaud B; FRENCHIE Study Investigators.

Kidney Int. 2017 Jun;91(6):1495-1509. doi: 10.1016/j.kint.2017.01.013. Epub 2017 Mar 18.


Impact of fluid status and inflammation and their interaction on survival: a study in an international hemodialysis patient cohort.

Dekker MJ, Marcelli D, Canaud BJ, Carioni P, Wang Y, Grassmann A, Konings CJ, Kotanko P, Leunissen KM, Levin NW, van der Sande FM, Ye X, Maheshwari V, Usvyat LA, Kooman JP; MONDO Initiative.

Kidney Int. 2017 May;91(5):1214-1223. doi: 10.1016/j.kint.2016.12.008. Epub 2017 Feb 13.


Intradialytic Cardiac Magnetic Resonance Imaging to Assess Cardiovascular Responses in a Short-Term Trial of Hemodiafiltration and Hemodialysis.

Buchanan C, Mohammed A, Cox E, Köhler K, Canaud B, Taal MW, Selby NM, Francis S, McIntyre CW.

J Am Soc Nephrol. 2017 Apr;28(4):1269-1277. doi: 10.1681/ASN.2016060686. Epub 2016 Nov 10.


Mortality reduction by post-dilution online-haemodiafiltration: a cause-specific analysis.

Nubé MJ, Peters SAE, Blankestijn PJ, Canaud B, Davenport A, Grooteman MPC, Asci G, Locatelli F, Maduell F, Morena M, Ok E, Torres F, Bots ML; HDF Pooling Project investigators.

Nephrol Dial Transplant. 2017 Mar 1;32(3):548-555. doi: 10.1093/ndt/gfw381.


Initiation of Renal-Replacement Therapy in the Intensive Care Unit.

Canaud B, Cohen EP.

N Engl J Med. 2016 Nov 10;375(19):1901. doi: 10.1056/NEJMc1610500. No abstract available.


Clinical Performance Assessment of CorDiax Filters in Hemodialysis and Hemodiafiltration.

Potier J, Bowry S, Canaud B.

Contrib Nephrol. 2017;189:237-245. Epub 2016 Dec 12.


What Is the Optimal Target Convective Volume in On-Line Hemodiafiltration Therapy?

Canaud B, Koehler K, Bowry S, Stuard S.

Contrib Nephrol. 2017;189:9-16. Epub 2016 Dec 12. Review.


Improving outcomes of dialysis patients by population health management-the Global Chief Medical Officer Initiative.

Canaud B, Hegbrant J, Nissenson AR, Barth C, Maddux F, Etter M, Krishnan M.

Lancet. 2016 Oct 22;388(10055):1966-1967. doi: 10.1016/S0140-6736(16)31894-3. No abstract available.


Patients' Characteristics Affect the Survival Benefit of Warfarin Treatment for Hemodialysis Patients with Atrial Fibrillation. A Historical Cohort Study.

Brancaccio D, Neri L, Bellocchio F, Barbieri C, Amato C, Mari F, Canaud B, Stuard S.

Am J Nephrol. 2016;44(4):258-267. Epub 2016 Sep 7.

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