Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 210


The imprint of microfibres in southern European deep seas.

Sanchez-Vidal A, Thompson RC, Canals M, de Haan WP.

PLoS One. 2018 Nov 5;13(11):e0207033. doi: 10.1371/journal.pone.0207033. eCollection 2018.


Correction: Ticks from diverse genera encode chemokine-inhibitory evasin proteins.

Hayward J, Sanchez J, Perry A, Huang C, Valle MR, Canals M, Payne RJ, Stone MJ.

J Biol Chem. 2018 Oct 12;293(41):15888. doi: 10.1074/jbc.AAC118.005871. No abstract available.


Preassembled GPCR signaling complexes mediate distinct cellular responses to ultralow ligand concentrations.

Civciristov S, Ellisdon AM, Suderman R, Pon CK, Evans BA, Kleifeld O, Charlton SJ, Hlavacek WS, Canals M, Halls ML.

Sci Signal. 2018 Oct 9;11(551). pii: eaan1188. doi: 10.1126/scisignal.aan1188.


Influence of deep water formation by open-sea convection on the transport of low hydrophobicity organic pollutants in the NW Mediterranean Sea.

Salvadó JA, Grimalt JO, López JF, Palanques A, Canals M.

Sci Total Environ. 2019 Jan 10;647:597-605. doi: 10.1016/j.scitotenv.2018.07.458. Epub 2018 Aug 1.


Multisite phosphorylation is required for sustained interaction with GRKs and arrestins during rapid μ-opioid receptor desensitization.

Miess E, Gondin AB, Yousuf A, Steinborn R, Mösslein N, Yang Y, Göldner M, Ruland JG, Bünemann M, Krasel C, Christie MJ, Halls ML, Schulz S, Canals M.

Sci Signal. 2018 Jul 17;11(539). pii: eaas9609. doi: 10.1126/scisignal.aas9609.


Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome.

Jimenez-Vargas NN, Pattison LA, Zhao P, Lieu T, Latorre R, Jensen DD, Castro J, Aurelio L, Le GT, Flynn B, Herenbrink CK, Yeatman HR, Edgington-Mitchell L, Porter CJH, Halls ML, Canals M, Veldhuis NA, Poole DP, McLean P, Hicks GA, Scheff N, Chen E, Bhattacharya A, Schmidt BL, Brierley SM, Vanner SJ, Bunnett NW.

Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):E7438-E7447. doi: 10.1073/pnas.1721891115. Epub 2018 Jul 16.


Inflammation-associated changes in DOR expression and function in the mouse colon.

DiCello JJ, Saito A, Rajasekhar P, Eriksson EM, McQuade RM, Nowell CJ, Sebastian BW, Fichna J, Veldhuis NA, Canals M, Bunnett NW, Carbone SE, Poole DP.

Am J Physiol Gastrointest Liver Physiol. 2018 Oct 1;315(4):G544-G559. doi: 10.1152/ajpgi.00025.2018. Epub 2018 Jun 21.


Proteomic Identification of Interferon-Induced Proteins with Tetratricopeptide Repeats as Markers of M1 Macrophage Polarization.

Huang C, Lewis C, Borg NA, Canals M, Diep H, Drummond GR, Goode RJ, Schittenhelm RB, Vinh A, Zhu M, Kemp-Harper B, Kleifeld O, Stone MJ.

J Proteome Res. 2018 Apr 6;17(4):1485-1499. doi: 10.1021/acs.jproteome.7b00828. Epub 2018 Mar 13.


Fluorescently Labeled Morphine Derivatives for Bioimaging Studies.

Lam R, Gondin AB, Canals M, Kellam B, Briddon SJ, Graham B, Scammells PJ.

J Med Chem. 2018 Feb 8;61(3):1316-1329. doi: 10.1021/acs.jmedchem.7b01811. Epub 2018 Jan 10.


The sexual health approach in postmenopause: The five-minutes study.

Cuerva MJ, Gonzalez D, Canals M, Otero B, Espinosa JA, Molero F, Senturk LM, Mendoza N; SMS Young Experts Group.

Maturitas. 2018 Feb;108:31-36. doi: 10.1016/j.maturitas.2017.11.009. Epub 2017 Nov 11.


Pharmacologic Evidence for a Putative Conserved Allosteric Site on Opioid Receptors.

Livingston KE, Stanczyk MA, Burford NT, Alt A, Canals M, Traynor JR.

Mol Pharmacol. 2018 Feb;93(2):157-167. doi: 10.1124/mol.117.109561. Epub 2017 Dec 12.


Assessing the risk zones of Chagas' disease in Chile, in a world marked by global climatic change.

Tapia-Garay V, Figueroa DP, Maldonado A, Frías-Laserre D, Gonzalez CR, Parra A, Canals L, Apt W, Alvarado S, Cáceres D, Canals M.

Mem Inst Oswaldo Cruz. 2018 Jan;113(1):24-29. doi: 10.1590/0074-02760170172.


Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission.

Yarwood RE, Imlach WL, Lieu T, Veldhuis NA, Jensen DD, Klein Herenbrink C, Aurelio L, Cai Z, Christie MJ, Poole DP, Porter CJH, McLean P, Hicks GA, Geppetti P, Halls ML, Canals M, Bunnett NW.

Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):12309-12314. doi: 10.1073/pnas.1706656114. Epub 2017 Oct 30.


Genetically Encoded FRET Biosensors to Illuminate Compartmentalised GPCR Signalling.

Halls ML, Canals M.

Trends Pharmacol Sci. 2018 Feb;39(2):148-157. doi: 10.1016/ Epub 2017 Oct 17. Review.


Corrigendum: A submarine volcanic eruption leads to a novel microbial habitat.

Danovaro R, Canals M, Tangherlini M, Dell'Anno A, Gambi C, Lastras G, Amblas D, Sanchez-Vidal A, Frigola J, Calafat AM, Pedrosa-Pàmies R, Rivera J, Rayo X, Corinaldesi C.

Nat Ecol Evol. 2017 May 22;1(6):187. doi: 10.1038/s41559-017-0187.


A submarine volcanic eruption leads to a novel microbial habitat.

Danovaro R, Canals M, Tangherlini M, Dell'Anno A, Gambi C, Lastras G, Amblas D, Sanchez-Vidal A, Frigola J, Calafat AM, Pedrosa-Pàmies R, Rivera J, Rayo X, Corinaldesi C.

Nat Ecol Evol. 2017 Apr 24;1(6):144. doi: 10.1038/s41559-017-0144. Erratum in: Nat Ecol Evol. 2017 May 22;1(6):187.


Ticks from diverse genera encode chemokine-inhibitory evasin proteins.

Hayward J, Sanchez J, Perry A, Huang C, Rodriguez Valle M, Canals M, Payne RJ, Stone MJ.

J Biol Chem. 2017 Sep 22;292(38):15670-15680. doi: 10.1074/jbc.M117.807255. Epub 2017 Aug 4. Erratum in: J Biol Chem. 2018 Oct 12;293(41):15888.


[What do the numbers tell us about the temporal evolution of Chagas' disease?]

Canals M, González C, Canals L, Canals A, Cáceres D, Alvarado S, Cattan PE, Saavedra M, Zulantay I, Apt W.

Rev Chilena Infectol. 2017 Apr;34(2):120-127. doi: 10.4067/S0716-10182017000200004. Spanish.


Mercury concentrations in lean fish from the Western Mediterranean Sea: Dietary exposure and risk assessment in the population of the Balearic Islands.

Llull RM, Garí M, Canals M, Rey-Maquieira T, Grimalt JO.

Environ Res. 2017 Oct;158:16-23. doi: 10.1016/j.envres.2017.05.033. Epub 2017 Jun 6.


Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief.

Jensen DD, Lieu T, Halls ML, Veldhuis NA, Imlach WL, Mai QN, Poole DP, Quach T, Aurelio L, Conner J, Herenbrink CK, Barlow N, Simpson JS, Scanlon MJ, Graham B, McCluskey A, Robinson PJ, Escriou V, Nassini R, Materazzi S, Geppetti P, Hicks GA, Christie MJ, Porter CJH, Canals M, Bunnett NW.

Sci Transl Med. 2017 May 31;9(392). pii: eaal3447. doi: 10.1126/scitranslmed.aal3447.


Key determinants of selective binding and activation by the monocyte chemoattractant proteins at the chemokine receptor CCR2.

Huma ZE, Sanchez J, Lim HD, Bridgford JL, Huang C, Parker BJ, Pazhamalil JG, Porebski BT, Pfleger KDG, Lane JR, Canals M, Stone MJ.

Sci Signal. 2017 May 23;10(480). pii: eaai8529. doi: 10.1126/scisignal.aai8529.


Environmental hazard assessment of a marine mine tailings deposit site and potential implications for deep-sea mining.

Mestre NC, Rocha TL, Canals M, Cardoso C, Danovaro R, Dell'Anno A, Gambi C, Regoli F, Sanchez-Vidal A, Bebianno MJ.

Environ Pollut. 2017 Sep;228:169-178. doi: 10.1016/j.envpol.2017.05.027. Epub 2017 May 19.


Resilience of benthic deep-sea fauna to mining activities.

Gollner S, Kaiser S, Menzel L, Jones DOB, Brown A, Mestre NC, van Oevelen D, Menot L, Colaço A, Canals M, Cuvelier D, Durden JM, Gebruk A, Egho GA, Haeckel M, Marcon Y, Mevenkamp L, Morato T, Pham CK, Purser A, Sanchez-Vidal A, Vanreusel A, Vink A, Martinez Arbizu P.

Mar Environ Res. 2017 Aug;129:76-101. doi: 10.1016/j.marenvres.2017.04.010. Epub 2017 Apr 13. Review.


Modeling Chagas disease in Chile: From vector to congenital transmission.

Canals M, Cáceres D, Alvarado S, Canals A, Cattan PE.

Biosystems. 2017 Jun - Jul;156-157:63-71. doi: 10.1016/j.biosystems.2017.04.004. Epub 2017 Apr 20.


Wing Polymorphism and Trypanosoma cruzi Infection in Wild, Peridomestic, and Domestic Collections of Mepraia spinolai (Hemiptera: Reduviidae) From Chile.

Frías-Lasserre D, González CR, Valenzuela CR, de Carvalho DB, Oliveira J, Canals M, da Rosa JA.

J Med Entomol. 2017 Jul 1;54(4):1061-1066. doi: 10.1093/jme/tjx061. Erratum in: J Med Entomol. 2017 Jul 1;54(4):1099.


Niche modelling of the Chilean recluse spider Loxosceles laeta and araneophagic spitting spider Scytodes globula and risk for loxoscelism in Chile.

Canals M, Taucare-Rios A, Brescovit AD, Peña-Gomez F, Bizama G, Canals A, Moreno L, Bustamante R.

Med Vet Entomol. 2016 Dec;30(4):383-391. doi: 10.1111/mve.12184. Epub 2016 Jul 18.


Estimation of the Effect of the Predator Scytodes globula (Araneae: Scytodidae) on Loxosceles laeta (Araneae: Sicariidae) Populations.

Canals M, Moreno L, Solís R.

Environ Entomol. 2016 Aug;45(4):841-7. doi: 10.1093/ee/nvw075. Epub 2016 Jul 1.


Distribution and trafficking of the μ-opioid receptor in enteric neurons of the guinea pig.

Lay J, Carbone SE, DiCello JJ, Bunnett NW, Canals M, Poole DP.

Am J Physiol Gastrointest Liver Physiol. 2016 Aug 1;311(2):G252-66. doi: 10.1152/ajpgi.00184.2016. Epub 2016 Jun 30.


Systematic analysis of factors influencing observations of biased agonism at the mu-opioid receptor.

Thompson GL, Lane JR, Coudrat T, Sexton PM, Christopoulos A, Canals M.

Biochem Pharmacol. 2016 Aug 1;113:70-87. doi: 10.1016/j.bcp.2016.05.014. Epub 2016 Jun 7.


Morphometry of Concepcion Bank: Evidence of Geological and Biological Processes on a Large Volcanic Seamount of the Canary Islands Seamount Province.

Rivera J, Canals M, Lastras G, Hermida N, Amblas D, Arrese B, Martín-Sosa P, Acosta J.

PLoS One. 2016 May 31;11(5):e0156337. doi: 10.1371/journal.pone.0156337. eCollection 2016.


Cold-Water Corals and Anthropogenic Impacts in La Fonera Submarine Canyon Head, Northwestern Mediterranean Sea.

Lastras G, Canals M, Ballesteros E, Gili JM, Sanchez-Vidal A.

PLoS One. 2016 May 16;11(5):e0155729. doi: 10.1371/journal.pone.0155729. eCollection 2016.


Protein Kinase D and Gβγ Subunits Mediate Agonist-evoked Translocation of Protease-activated Receptor-2 from the Golgi Apparatus to the Plasma Membrane.

Jensen DD, Zhao P, Jimenez-Vargas NN, Lieu T, Gerges M, Yeatman HR, Canals M, Vanner SJ, Poole DP, Bunnett NW.

J Biol Chem. 2016 May 20;291(21):11285-99. doi: 10.1074/jbc.M115.710681. Epub 2016 Mar 30.


The role of kinetic context in apparent biased agonism at GPCRs.

Klein Herenbrink C, Sykes DA, Donthamsetti P, Canals M, Coudrat T, Shonberg J, Scammells PJ, Capuano B, Sexton PM, Charlton SJ, Javitch JA, Christopoulos A, Lane JR.

Nat Commun. 2016 Feb 24;7:10842. doi: 10.1038/ncomms10842.


Plasma membrane localization of the μ-opioid receptor controls spatiotemporal signaling.

Halls ML, Yeatman HR, Nowell CJ, Thompson GL, Gondin AB, Civciristov S, Bunnett NW, Lambert NA, Poole DP, Canals M.

Sci Signal. 2016 Feb 9;9(414):ra16. doi: 10.1126/scisignal.aac9177.


Proposed Mode of Binding and Action of Positive Allosteric Modulators at Opioid Receptors.

Shang Y, Yeatman HR, Provasi D, Alt A, Christopoulos A, Canals M, Filizola M.

ACS Chem Biol. 2016 May 20;11(5):1220-9. doi: 10.1021/acschembio.5b00712. Epub 2016 Feb 17.


Synthesis, Biological Evaluation, and Utility of Fluorescent Ligands Targeting the μ-Opioid Receptor.

Schembri LS, Stoddart LA, Briddon SJ, Kellam B, Canals M, Graham B, Scammells PJ.

J Med Chem. 2015 Dec 24;58(24):9754-67. doi: 10.1021/acs.jmedchem.5b01664. Epub 2015 Dec 16.


Chile Confronts its Environmental Health Future After 25 Years of Accelerated Growth.

Pino P, Iglesias V, Garreaud R, Cortés S, Canals M, Folch W, Burgos S, Levy K, Naeher LP, Steenland K.

Ann Glob Health. 2015 May-Jun;81(3):354-67. doi: 10.1016/j.aogh.2015.06.008. Review.


Persistent natural acidification drives major distribution shifts in marine benthic ecosystems.

Linares C, Vidal M, Canals M, Kersting DK, Amblas D, Aspillaga E, Cebrián E, Delgado-Huertas A, Díaz D, Garrabou J, Hereu B, Navarro L, Teixidó N, Ballesteros E.

Proc Biol Sci. 2015 Nov 7;282(1818):20150587. doi: 10.1098/rspb.2015.0587.


Interactions Between the Chilean Recluse Spider (Araneae: Sicariidae) and an Araneophagic Spitting Spider (Araneae: Scytodidae).

Canals M, Arriagada N, Solís R.

J Med Entomol. 2015 Mar;52(2):109-16. doi: 10.1093/jme/tju021. Epub 2015 Feb 2.


Adaptation of the spiders to the environment: the case of some Chilean species.

Canals M, Veloso C, Solís R.

Front Physiol. 2015 Aug 11;6:220. doi: 10.3389/fphys.2015.00220. eCollection 2015. Review.


Detection and Quantification of Intracellular Signaling Using FRET-Based Biosensors and High Content Imaging.

Halls ML, Poole DP, Ellisdon AM, Nowell CJ, Canals M.

Methods Mol Biol. 2015;1335:131-61. doi: 10.1007/978-1-4939-2914-6_10.


The Complex Roles of μ-Opioid Receptor Phosphorylation: A Key Determinant in Receptor Signaling and Regulation.

Canals M.

Mol Pharmacol. 2015 Oct;88(4):814-5. doi: 10.1124/mol.115.100180. Epub 2015 Jul 7.


The deep sea is a major sink for microplastic debris.

Woodall LC, Sanchez-Vidal A, Canals M, Paterson GL, Coppock R, Sleight V, Calafat A, Rogers AD, Narayanaswamy BE, Thompson RC.

R Soc Open Sci. 2014 Dec 17;1(4):140317. doi: 10.1098/rsos.140317. eCollection 2014 Dec.


Biased Agonism of Endogenous Opioid Peptides at the μ-Opioid Receptor.

Thompson GL, Lane JR, Coudrat T, Sexton PM, Christopoulos A, Canals M.

Mol Pharmacol. 2015 Aug;88(2):335-46. doi: 10.1124/mol.115.098848. Epub 2015 May 26.


Delivery of unprecedented amounts of perfluoroalkyl substances towards the deep-sea.

Sanchez-Vidal A, Llorca M, Farré M, Canals M, Barceló D, Puig P, Calafat A.

Sci Total Environ. 2015 Sep 1;526:41-8. doi: 10.1016/j.scitotenv.2015.04.080. Epub 2015 Apr 25.


Discovery, synthesis, and molecular pharmacology of selective positive allosteric modulators of the δ-opioid receptor.

Burford NT, Livingston KE, Canals M, Ryan MR, Budenholzer LM, Han Y, Shang Y, Herbst JJ, O'Connell J, Banks M, Zhang L, Filizola M, Bassoni DL, Wehrman TS, Christopoulos A, Traynor JR, Gerritz SW, Alt A.

J Med Chem. 2015 May 28;58(10):4220-9. doi: 10.1021/acs.jmedchem.5b00007. Epub 2015 May 7.


A MSFD complementary approach for the assessment of pressures, knowledge and data gaps in Southern European Seas: The PERSEUS experience.

Crise A, Kaberi H, Ruiz J, Zatsepin A, Arashkevich E, Giani M, Karageorgis AP, Prieto L, Pantazi M, Gonzalez-Fernandez D, Ribera d'Alcalà M, Tornero V, Vassilopoulou V, Durrieu de Madron X, Guieu C, Puig P, Zenetos A, Andral B, Angel D, Altukhov D, Ayata SD, Aktan Y, Balcıoğlu E, Benedetti F, Bouchoucha M, Buia MC, Cadiou JF, Canals M, Chakroun M, Christou E, Christidis MG, Civitarese G, Coatu V, Corsini-Foka M, Cozzi S, Deidun A, Dell'Aquila A, Dogrammatzi A, Dumitrache C, Edelist D, Ettahiri O, Fonda-Umani S, Gana S, Galgani F, Gasparini S, Giannakourou A, Gomoiu MT, Gubanova A, Gücü AC, Gürses Ö, Hanke G, Hatzianestis I, Herut B, Hone R, Huertas E, Irisson JO, İşinibilir M, Jimenez JA, Kalogirou S, Kapiris K, Karamfilov V, Kavadas S, Keskin Ç, Kideyş AE, Kocak M, Kondylatos G, Kontogiannis C, Kosyan R, Koubbi P, Kušpilić G, La Ferla R, Langone L, Laroche S, Lazar L, Lefkaditou E, Lemeshko IE, Machias A, Malej A, Mazzocchi MG, Medinets V, Mihalopoulos N, Miserocchi S, Moncheva S, Mukhanov V, Oaie G, Oros A, Öztürk AA, Öztürk B, Panayotova M, Prospathopoulos A, Radu G, Raykov V, Reglero P, Reygondeau G, Rougeron N, Salihoglu B, Sanchez-Vidal A, Sannino G, Santinelli C, Secrieru D, Shapiro G, Simboura N, Shiganova T, Sprovieri M, Stefanova K, Streftaris N, Tirelli V, Tom M, Topaloğlu B, Topçu NE, Tsagarakis K, Tsangaris C, Tserpes G, Tuğrul S, Uysal Z, Vasile D, Violaki K, Xu J, Yüksek A, Papathanassiou E.

Mar Pollut Bull. 2015 Jun 15;95(1):28-39. doi: 10.1016/j.marpolbul.2015.03.024. Epub 2015 Apr 16.


The effects of temperature on the gas exchange cycle in Agathemera crassa.

Thienel M, Canals M, Bozinovic F, Veloso C.

Comp Biochem Physiol A Mol Integr Physiol. 2015 May;183:126-30. doi: 10.1016/j.cbpa.2015.01.006. Epub 2015 Jan 23.


Detection and quantification of allosteric modulation of endogenous m4 muscarinic acetylcholine receptor using impedance-based label-free technology in a neuronal cell line.

Chen AN, Malone DT, Pabreja K, Sexton PM, Christopoulos A, Canals M.

J Biomol Screen. 2015 Jun;20(5):646-54. doi: 10.1177/1087057114563025. Epub 2014 Dec 22.


Biological redundancy of endogenous GPCR ligands in the gut and the potential for endogenous functional selectivity.

Thompson GL, Canals M, Poole DP.

Front Pharmacol. 2014 Nov 28;5:262. doi: 10.3389/fphar.2014.00262. eCollection 2014. Review.

Supplemental Content

Loading ...
Support Center