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Items: 1 to 50 of 93

1.

Targeting PML in triple negative breast cancer elicits growth suppression and senescence.

Arreal L, Piva M, Fernández S, Revandkar A, Schaub-Clerigué A, Villanueva J, Zabala-Letona A, Pujana M, Astobiza I, Cortazar AR, Hermanova I, Bozal-Basterra L, Arruabarrena-Aristorena A, Crespo JR, Valcarcel-Jimenez L, Zúñiga-García P, Canals F, Torrano V, Barrio R, Sutherland JD, Alimonti A, Martin-Martin N, Carracedo A.

Cell Death Differ. 2019 Oct 1. doi: 10.1038/s41418-019-0407-5. [Epub ahead of print]

PMID:
31570853
2.

Proteomics Analysis of Extracellular Matrix Remodeling During Zebrafish Heart Regeneration.

Garcia-Puig A, Mosquera JL, Jiménez-Delgado S, García-Pastor C, Jorba I, Navajas D, Canals F, Raya A.

Mol Cell Proteomics. 2019 Sep;18(9):1745-1755. doi: 10.1074/mcp.RA118.001193. Epub 2019 Jun 20.

3.
4.

Sweet and Sour Ehrlichia: Glycoproteomics and Phosphoproteomics Reveal New Players in Ehrlichia ruminantium Physiology and Pathogenesis.

Marcelino I, Colomé-Calls N, Holzmuller P, Lisacek F, Reynaud Y, Canals F, Vachiéry N.

Front Microbiol. 2019 Mar 15;10:450. doi: 10.3389/fmicb.2019.00450. eCollection 2019.

5.

Global Protein Stabilization Does Not Suffice to Prevent Amyloid Fibril Formation.

Marinelli P, Navarro S, Baño-Polo M, Morel B, Graña-Montes R, Sabe A, Canals F, Fernandez MR, Conejero-Lara F, Ventura S.

ACS Chem Biol. 2018 Aug 17;13(8):2094-2105. doi: 10.1021/acschembio.8b00607. Epub 2018 Jul 16.

PMID:
29966079
6.

CCL23: a new CC chemokine involved in human brain damage.

Simats A, García-Berrocoso T, Penalba A, Giralt D, Llovera G, Jiang Y, Ramiro L, Bustamante A, Martinez-Saez E, Canals F, Wang X, Liesz A, Rosell A, Montaner J.

J Intern Med. 2018 May;283(5):461-475. doi: 10.1111/joim.12738. Epub 2018 Mar 5.

PMID:
29415332
7.

Disulfide driven folding for a conditionally disordered protein.

Fraga H, Pujols J, Gil-Garcia M, Roque A, Bernardo-Seisdedos G, Santambrogio C, Bech-Serra JJ, Canals F, Bernadó P, Grandori R, Millet O, Ventura S.

Sci Rep. 2017 Dec 5;7(1):16994. doi: 10.1038/s41598-017-17259-4.

8.

Single Cell Immuno-Laser Microdissection Coupled to Label-Free Proteomics to Reveal the Proteotypes of Human Brain Cells After Ischemia.

García-Berrocoso T, Llombart V, Colàs-Campàs L, Hainard A, Licker V, Penalba A, Ramiro L, Simats A, Bustamante A, Martínez-Saez E, Canals F, Sanchez JC, Montaner J.

Mol Cell Proteomics. 2018 Jan;17(1):175-189. doi: 10.1074/mcp.RA117.000419. Epub 2017 Nov 13.

9.

Developments in early diagnosis and therapy of HIV infection in newborns.

Canals F, Masiá M, Gutiérrez F.

Expert Opin Pharmacother. 2018 Jan;19(1):13-25. doi: 10.1080/14656566.2017.1363180. Epub 2017 Aug 11. Review.

PMID:
28764578
10.

Serum depletion induces changes in protein expression in the trophoblast-derived cell line HTR-8/SVneo.

Novoa-Herran S, Umaña-Perez A, Canals F, Sanchez-Gomez M.

Cell Mol Biol Lett. 2016 Oct 16;21:22. doi: 10.1186/s11658-016-0018-9. eCollection 2016.

11.

Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition.

Mateo F, Arenas EJ, Aguilar H, Serra-Musach J, de Garibay GR, Boni J, Maicas M, Du S, Iorio F, Herranz-Ors C, Islam A, Prado X, Llorente A, Petit A, Vidal A, Català I, Soler T, Venturas G, Rojo-Sebastian A, Serra H, Cuadras D, Blanco I, Lozano J, Canals F, Sieuwerts AM, de Weerd V, Look MP, Puertas S, García N, Perkins AS, Bonifaci N, Skowron M, Gómez-Baldó L, Hernández V, Martínez-Aranda A, Martínez-Iniesta M, Serrat X, Cerón J, Brunet J, Barretina MP, Gil M, Falo C, Fernández A, Morilla I, Pernas S, Plà MJ, Andreu X, Seguí MA, Ballester R, Castellà E, Nellist M, Morales S, Valls J, Velasco A, Matias-Guiu X, Figueras A, Sánchez-Mut JV, Sánchez-Céspedes M, Cordero A, Gómez-Miragaya J, Palomero L, Gómez A, Gajewski TF, Cohen EEW, Jesiotr M, Bodnar L, Quintela-Fandino M, López-Bigas N, Valdés-Mas R, Puente XS, Viñals F, Casanovas O, Graupera M, Hernández-Losa J, Ramón Y Cajal S, García-Alonso L, Saez-Rodriguez J, Esteller M, Sierra A, Martín-Martín N, Matheu A, Carracedo A, González-Suárez E, Nanjundan M, Cortés J, Lázaro C, Odero MD, Martens JWM, Moreno-Bueno G, Barcellos-Hoff MH, Villanueva A, Gomis RR, Pujana MA.

Oncogene. 2017 May 11;36(19):2737-2749. doi: 10.1038/onc.2016.427. Epub 2016 Dec 19.

12.

A multicentric study to evaluate the use of relative retention times in targeted proteomics.

Vialas V, Colomé-Calls N, Abian J, Aloria K, Alvarez-Llamas G, Antúnez O, Arizmendi JM, Azkargorta M, Barceló-Batllori S, Barderas MG, Blanco F, Casal JI, Casas V, de la Torre C, Chicano-Gálvez E, Elortza F, Espadas G, Estanyol JM, Fernandez-Irigoyen J, Fernandez-Puente P, Fidalgo MJ, Fuentes M, Gay M, Gil C, Hainard A, Hernaez ML, Ibarrola N, Kopylov AT, Lario A, Lopez JA, López-Lucendo M, Marcilla M, Marina-Ramírez A, Marko-Varga G, Martín L, Mora MI, Morato-López E, Muñoz J, Odena MA, de Oliveira E, Orera I, Ortea I, Pasquarello C, Ray KB, Rezeli M, Ruppen I, Sabidó E, Del Pino MMS, Sancho J, Santamaría E, Vazquez J, Vilaseca M, Vivanco F, Walters JJ, Zgoda VG, Corrales FJ, Canals F, Paradela A.

J Proteomics. 2017 Jan 30;152:138-149. doi: 10.1016/j.jprot.2016.10.014. Epub 2016 Oct 29.

PMID:
27989941
13.

PI3 kinase inhibition improves vascular malformations in mouse models of hereditary haemorrhagic telangiectasia.

Ola R, Dubrac A, Han J, Zhang F, Fang JS, Larrivée B, Lee M, Urarte AA, Kraehling JR, Genet G, Hirschi KK, Sessa WC, Canals FV, Graupera M, Yan M, Young LH, Oh PS, Eichmann A.

Nat Commun. 2016 Nov 29;7:13650. doi: 10.1038/ncomms13650.

14.

Profiling and identification of new proteins involved in brain ischemia using MALDI-imaging-mass-spectrometry.

Llombart V, Trejo SA, Bronsoms S, Morancho A, Feifei M, Faura J, García-Berrocoso T, Simats A, Rosell A, Canals F, Hernández-Guillamón M, Montaner J.

J Proteomics. 2017 Jan 30;152:243-253. doi: 10.1016/j.jprot.2016.11.014. Epub 2016 Nov 22.

PMID:
27888142
15.

A Comparative Analysis of the Peptide Repertoires of HLA-DR Molecules Differentially Associated With Rheumatoid Arthritis.

Scholz E, Mestre-Ferrer A, Daura X, García-Medel N, Carrascal M, James EA, Kwok WW, Canals F, Álvarez I.

Arthritis Rheumatol. 2016 Oct;68(10):2412-21. doi: 10.1002/art.39736.

16.

Characterization of secretomes from a human blood brain barrier endothelial cells in-vitro model after ischemia by stable isotope labeling with aminoacids in cell culture (SILAC).

Llombart V, García-Berrocoso T, Bech-Serra JJ, Simats A, Bustamante A, Giralt D, Reverter-Branchat G, Canals F, Hernández-Guillamon M, Montaner J.

J Proteomics. 2016 Feb 5;133:100-112. doi: 10.1016/j.jprot.2015.12.011. Epub 2015 Dec 21.

PMID:
26718731
17.

Cystatin D locates in the nucleus at sites of active transcription and modulates gene and protein expression.

Ferrer-Mayorga G, Alvarez-Díaz S, Valle N, De Las Rivas J, Mendes M, Barderas R, Canals F, Tapia O, Casal JI, Lafarga M, Muñoz A.

J Biol Chem. 2015 Oct 30;290(44):26533-48. doi: 10.1074/jbc.M115.660175. Epub 2015 Sep 13.

18.

Protein expression parallels thermal tolerance and ecologic changes in the diversification of a diving beetle species complex.

Hidalgo-Galiana A, Monge M, Biron DG, Canals F, Ribera I, Cieslak A.

Heredity (Edinb). 2016 Jan;116(1):114-23. doi: 10.1038/hdy.2015.80. Epub 2015 Sep 2.

19.

Optimized Proteomic Mass Spectrometry Characterization of Recombinant Human μ-Opioid Receptor Functionally Expressed in Pichia pastoris Cell Lines.

Rosa M, Bech-Serra JJ, Canals F, Zajac JM, Talmont F, Arsequell G, Valencia G.

J Proteome Res. 2015 Aug 7;14(8):3162-73. doi: 10.1021/acs.jproteome.5b00104. Epub 2015 Jul 7.

PMID:
26090583
20.

Multicenter experiment for quality control of peptide-centric LC-MS/MS analysis - A longitudinal performance assessment with nLC coupled to orbitrap MS analyzers.

Campos A, Díaz R, Martínez-Bartolomé S, Sierra J, Gallardo O, Sabidó E, López-Lucendo M, Ignacio Casal J, Pasquarello C, Scherl A, Chiva C, Borras E, Odena A, Elortza F, Azkargorta M, Ibarrola N, Canals F, Albar JP, Oliveira E.

J Proteomics. 2015 Sep 8;127(Pt B):264-74. doi: 10.1016/j.jprot.2015.05.012. Epub 2015 May 14.

PMID:
25982386
21.

Central T cell tolerance: Identification of tissue-restricted autoantigens in the thymus HLA-DR peptidome.

Alvarez I, Collado JA, Colobran R, Carrascal M, Ciudad MT, Canals F, James EA, Kwok WW, Gärtner M, Kyewski B, Pujol-Borrell R, Jaraquemada D.

J Autoimmun. 2015 Jun;60:12-9. doi: 10.1016/j.jaut.2015.03.004. Epub 2015 Apr 21.

PMID:
25911201
22.

Quantitative analysis of post-translational modifications in human serum transthyretin associated with familial amyloidotic polyneuropathy by targeted LC-MS and intact protein MS.

Vilà-Rico M, Colomé-Calls N, Martín-Castel L, Gay M, Azorín S, Vilaseca M, Planas A, Canals F.

J Proteomics. 2015 Sep 8;127(Pt B):234-46. doi: 10.1016/j.jprot.2015.04.016. Epub 2015 Apr 21.

PMID:
25910794
23.

Nuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer.

Aguilera Ó, González-Sancho JM, Zazo S, Rincón R, Fernández AF, Tapia O, Canals F, Morte B, Calvanese V, Orgaz JL, Niell N, Aguilar S, Freije JM, Graña O, Pisano DG, Borrero A, Martínez-Useros J, Jiménez B, Fraga MF, García-Foncillas J, López-Otín C, Lafarga M, Rojo F, Muñoz A.

Oncotarget. 2015 Mar 20;6(8):5903-17.

24.

Photocoagulation of human retinal pigment epithelium in vitro: unravelling the effects on ARPE-19 by transcriptomics and proteomics.

Tababat-Khani P, de la Torre C, Canals F, Bennet H, Simo R, Hernandez C, Fex M, Agardh CD, Hansson O, Agardh E.

Acta Ophthalmol. 2015 Jun;93(4):348-54. doi: 10.1111/aos.12649. Epub 2015 Jan 21.

25.

A mouse model uncovers LKB1 as an UVB-induced DNA damage sensor mediating CDKN1A (p21WAF1/CIP1) degradation.

Esteve-Puig R, Gil R, González-Sánchez E, Bech-Serra JJ, Grueso J, Hernández-Losa J, Moliné T, Canals F, Ferrer B, Cortés J, Bastian B, Ramón Y Cajal S, Martín-Caballero J, Flores JM, Vivancos A, García-Patos V, Recio JÁ.

PLoS Genet. 2014 Oct 16;10(10):e1004721. doi: 10.1371/journal.pgen.1004721. eCollection 2014 Oct.

26.

Reproducibility and consistency of proteomic experiments on natural populations of a non-model aquatic insect.

Hidalgo-Galiana A, Monge M, Biron DG, Canals F, Ribera I, Cieslak A.

PLoS One. 2014 Aug 18;9(8):e104734. doi: 10.1371/journal.pone.0104734. eCollection 2014.

27.

Relevance of IGFBP2 proteolysis in glioma and contribution of the extracellular protease ADAMTS1.

Martino-Echarri E, Fernández-Rodríguez R, Bech-Serra JJ, Plaza-Calonge Mdel C, Vidal N, Casal C, Colomé N, Seoane J, Canals F, Rodríguez-Manzaneque JC.

Oncotarget. 2014 Jun 30;5(12):4295-304.

28.

Brain proteomics identifies potential simvastatin targets in acute phase of stroke in a rat embolic model.

Campos-Martorell M, Salvador N, Monge M, Canals F, García-Bonilla L, Hernández-Guillamon M, Ayuso MI, Chacón P, Rosell A, Alcazar A, Montaner J.

J Neurochem. 2014 Jul;130(2):301-12. doi: 10.1111/jnc.12719. Epub 2014 Apr 30.

29.

The mitochondrial intermembrane space oxireductase Mia40 funnels the oxidative folding pathway of the cytochrome c oxidase assembly protein Cox19.

Fraga H, Bech-Serra JJ, Canals F, Ortega G, Millet O, Ventura S.

J Biol Chem. 2014 Apr 4;289(14):9852-64. doi: 10.1074/jbc.M114.553479. Epub 2014 Feb 25.

30.

Standardization and quality control in proteomics.

Albar JP, Canals F.

J Proteomics. 2013 Dec 16;95:1-2. doi: 10.1016/j.jprot.2013.11.002. No abstract available.

PMID:
24275454
31.

Surfing transcriptomic landscapes. A step beyond the annotation of chromosome 16 proteome.

Segura V, Medina-Aunon JA, Mora MI, Martínez-Bartolomé S, Abian J, Aloria K, Antúnez O, Arizmendi JM, Azkargorta M, Barceló-Batllori S, Beaskoetxea J, Bech-Serra JJ, Blanco F, Monteiro MB, Cáceres D, Canals F, Carrascal M, Casal JI, Clemente F, Colomé N, Dasilva N, Díaz P, Elortza F, Fernández-Puente P, Fuentes M, Gallardo O, Gharbi SI, Gil C, González-Tejedo C, Hernáez ML, Lombardía M, Lopez-Lucendo M, Marcilla M, Mato JM, Mendes M, Oliveira E, Orera I, Pascual-Montano A, Prieto G, Ruiz-Romero C, Sánchez del Pino MM, Tabas-Madrid D, Valero ML, Vialas V, Villanueva J, Albar JP, Corrales FJ.

J Proteome Res. 2014 Jan 3;13(1):158-72. doi: 10.1021/pr400721r. Epub 2013 Nov 5.

PMID:
24138474
32.

From brain to blood: New biomarkers for ischemic stroke prognosis.

García-Berrocoso T, Penalba A, Boada C, Giralt D, Cuadrado E, Colomé N, Dayon L, Canals F, Sanchez JC, Rosell A, Montaner J.

J Proteomics. 2013 Dec 6;94:138-48. doi: 10.1016/j.jprot.2013.09.005. Epub 2013 Sep 20.

PMID:
24061000
33.

Peptides presented by HLA class I molecules in the human thymus.

Espinosa G, Collado JA, Scholz E, Mestre-Ferrer A, Kuse N, Takiguchi M, Carrascal M, Canals F, Pujol-Borrell R, Jaraquemada D, Alvarez I.

J Proteomics. 2013 Dec 6;94:23-36. doi: 10.1016/j.jprot.2013.08.023. Epub 2013 Sep 9.

PMID:
24029068
34.

Composition of the HLA-DR-associated human thymus peptidome.

Collado JA, Alvarez I, Ciudad MT, Espinosa G, Canals F, Pujol-Borrell R, Carrascal M, Abian J, Jaraquemada D.

Eur J Immunol. 2013 Sep;43(9):2273-82. doi: 10.1002/eji.201243280. Epub 2013 Jul 12.

35.

Identification of new pathogenic candidates for diabetic macular edema using fluorescence-based difference gel electrophoresis analysis.

Hernández C, García-Ramírez M, Colomé N, Corraliza L, García-Pascual L, Casado J, Canals F, Simó R.

Diabetes Metab Res Rev. 2013 Sep;29(6):499-506. doi: 10.1002/dmrr.2419.

PMID:
23568601
36.

Guidelines for reporting quantitative mass spectrometry based experiments in proteomics.

Martínez-Bartolomé S, Deutsch EW, Binz PA, Jones AR, Eisenacher M, Mayer G, Campos A, Canals F, Bech-Serra JJ, Carrascal M, Gay M, Paradela A, Navajas R, Marcilla M, Hernáez ML, Gutiérrez-Blázquez MD, Velarde LF, Aloria K, Beaskoetxea J, Medina-Aunon JA, Albar JP.

J Proteomics. 2013 Dec 16;95:84-8. doi: 10.1016/j.jprot.2013.02.026. Epub 2013 Mar 14.

PMID:
23500130
37.

PELO negatively regulates HER receptor signalling and metastasis.

Pedersen K, Canals F, Prat A, Tabernero J, Arribas J.

Oncogene. 2014 Feb 27;33(9):1190-7. doi: 10.1038/onc.2013.35. Epub 2013 Feb 25.

PMID:
23435426
38.

Constitutive HER2 signaling promotes breast cancer metastasis through cellular senescence.

Angelini PD, Zacarias Fluck MF, Pedersen K, Parra-Palau JL, Guiu M, Bernadó Morales C, Vicario R, Luque-García A, Navalpotro NP, Giralt J, Canals F, Gomis RR, Tabernero J, Baselga J, Villanueva J, Arribas J.

Cancer Res. 2013 Jan 1;73(1):450-8. doi: 10.1158/0008-5472.CAN-12-2301. Erratum in: Cancer Res. 2013 Oct 1;73(19):6095.

39.

Spanish human proteome project: dissection of chromosome 16.

Segura V, Medina-Aunon JA, Guruceaga E, Gharbi SI, González-Tejedo C, Sánchez del Pino MM, Canals F, Fuentes M, Casal JI, Martínez-Bartolomé S, Elortza F, Mato JM, Arizmendi JM, Abian J, Oliveira E, Gil C, Vivanco F, Blanco F, Albar JP, Corrales FJ.

J Proteome Res. 2013 Jan 4;12(1):112-22. doi: 10.1021/pr300898u. Epub 2012 Dec 12.

PMID:
23234512
40.

The protease MT1-MMP drives a combinatorial proteolytic program in activated endothelial cells.

Koziol A, Gonzalo P, Mota A, Pollán Á, Lorenzo C, Colomé N, Montaner D, Dopazo J, Arribas J, Canals F, Arroyo AG.

FASEB J. 2012 Nov;26(11):4481-94. doi: 10.1096/fj.12-205906. Epub 2012 Aug 2.

PMID:
22859368
41.

A dominant-negative N-terminal fragment of HER2 frequently expressed in breast cancers.

Morancho B, Parra-Palau JL, Ibrahim YH, Bernadó Morales C, Peg V, Bech-Serra JJ, Pandiella A, Canals F, Baselga J, Rubio I, Arribas J.

Oncogene. 2013 Mar 14;32(11):1452-9. doi: 10.1038/onc.2012.152. Epub 2012 May 28.

PMID:
22641219
42.

A comprehensive proteome of Mycoplasma genitalium.

Párraga-Niño N, Colomé-Calls N, Canals F, Querol E, Ferrer-Navarro M.

J Proteome Res. 2012 Jun 1;11(6):3305-16. doi: 10.1021/pr300084c. Epub 2012 May 23.

PMID:
22582988
43.

Tri-domain bifunctional inhibitor of metallocarboxypeptidases A and serine proteases isolated from marine annelid Sabellastarte magnifica.

Alonso-del-Rivero M, Trejo SA, Reytor ML, Rodriguez-de-la-Vega M, Delfin J, Diaz J, González-González Y, Canals F, Chavez MA, Aviles FX.

J Biol Chem. 2012 May 4;287(19):15427-38. doi: 10.1074/jbc.M111.337261. Epub 2012 Mar 12.

44.

Proteomic analysis of cerebrospinal fluid from obese women with idiopathic intracranial hypertension: a new approach for identifying new candidates in the pathogenesis of obesity.

Lecube A, Poca MA, Colomé N, Bech-Serra JJ, Hernández C, García-Ramírez M, Gándara D, Canals F, Simó R.

J Neuroendocrinol. 2012 Jun;24(6):944-52. doi: 10.1111/j.1365-2826.2012.02288.x.

PMID:
22296024
45.

Protein arginine methyltransferase 5 regulates ERK1/2 signal transduction amplitude and cell fate through CRAF.

Andreu-Pérez P, Esteve-Puig R, de Torre-Minguela C, López-Fauqued M, Bech-Serra JJ, Tenbaum S, García-Trevijano ER, Canals F, Merlino G, Avila MA, Recio JA.

Sci Signal. 2011 Sep 13;4(190):ra58. doi: 10.1126/scisignal.2001936.

46.

ADAM17 (TACE) regulates TGFβ signaling through the cleavage of vasorin.

Malapeira J, Esselens C, Bech-Serra JJ, Canals F, Arribas J.

Oncogene. 2011 Apr 21;30(16):1912-22. doi: 10.1038/onc.2010.565. Epub 2010 Dec 20.

PMID:
21170088
47.

Proteomic analysis in cerebrospinal fluid of patients with atypical nonketotic hyperglycinemia and pulmonary hypertension - A pilot study.

Rodríguez CE, Arranz JA, Colomé N, Bech-Serra JJ, Canals F, Del Toro M, Riudor E.

Proteomics Clin Appl. 2009 Dec;3(12):1430-9. doi: 10.1002/prca.200800251. Epub 2009 Oct 7.

PMID:
21136962
48.

The proteome of human brain after ischemic stroke.

Cuadrado E, Rosell A, Colomé N, Hernández-Guillamon M, García-Berrocoso T, Ribo M, Alcazar A, Ortega-Aznar A, Salinas M, Canals F, Montaner J.

J Neuropathol Exp Neurol. 2010 Nov;69(11):1105-15. doi: 10.1097/NEN.0b013e3181f8c539.

PMID:
20940630
49.

Proteomic analysis of electronegative low-density lipoprotein.

Bancells C, Canals F, Benítez S, Colomé N, Julve J, Ordóñez-Llanos J, Sánchez-Quesada JL.

J Lipid Res. 2010 Dec;51(12):3508-15. doi: 10.1194/jlr.M009258. Epub 2010 Aug 10.

50.

New pathogenic candidates for diabetic macular edema detected by proteomic analysis.

Hernández C, García-Ramírez M, Colomé N, Villarroel M, Corraliza L, García-Pacual L, Casado J, Canals F, Simó R.

Diabetes Care. 2010 Jul;33(7):e92. doi: 10.2337/dc10-0232. No abstract available.

PMID:
20587712

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