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Items: 1 to 50 of 143

1.

Yield parameters and antioxidant compounds of tomato fruit: the role of plant defence inducers with or without Cucumber mosaic virus infection.

Rendina N, Nuzzaci M, Sofo A, Campiglia P, Scopa A, Sommella E, Pepe G, De Nisco M, Basilicata MG, Manfra M.

J Sci Food Agric. 2019 May 20. doi: 10.1002/jsfa.9818. [Epub ahead of print]

PMID:
31106435
2.

Antidiabetic and Cardioprotective Effects of Pharmacological Inhibition of GRK2 in db/db Mice.

Cipolletta E, Gambardella J, Fiordelisi A, Del Giudice C, Di Vaia E, Ciccarelli M, Sala M, Campiglia P, Coscioni E, Trimarco B, Sorriento D, Iaccarino G.

Int J Mol Sci. 2019 Mar 25;20(6). pii: E1492. doi: 10.3390/ijms20061492.

3.

Corrigendum: Aquaporin-9 Contributes to the Maturation Process and Inflammatory Cytokine Secretion of Murine Dendritic Cells.

De Santis S, Serino G, Fiorentino MR, Galleggiante V, Gena P, Verna G, Liso M, Massaro M, Lan J, Troisi J, Cataldo I, Bertamino A, Pinto A, Campiglia P, Santino A, Giannelli G, Fasano A, Calamita G, Chieppa M.

Front Immunol. 2019 Feb 25;10:216. doi: 10.3389/fimmu.2019.00216. eCollection 2019.

4.

Identification of an indol-based multi-target kinase inhibitor through phenotype screening and target fishing using inverse virtual screening approach.

Ostacolo C, Di Sarno V, Lauro G, Pepe G, Musella S, Ciaglia T, Vestuto V, Autore G, Bifulco G, Marzocco S, Campiglia P, Gomez-Monterrey IM, Bertamino A.

Eur J Med Chem. 2019 Apr 1;167:61-75. doi: 10.1016/j.ejmech.2019.01.066. Epub 2019 Feb 6.

PMID:
30763817
5.

A Boost in Mitochondrial Activity Underpins the Cholesterol-Lowering Effect of Annurca Apple Polyphenols on Hepatic Cells.

Sommella E, Badolati N, Riccio G, Salviati E, Bottone S, Dentice M, Campiglia P, Tenore GC, Stornaiuolo M, Novellino E.

Nutrients. 2019 Jan 14;11(1). pii: E163. doi: 10.3390/nu11010163.

6.

Novel Potent Decameric Peptide of Spirulina platensis Reduces Blood Pressure Levels Through a PI3K/AKT/eNOS-Dependent Mechanism.

Carrizzo A, Conte GM, Sommella E, Damato A, Ambrosio M, Sala M, Scala MC, Aquino RP, De Lucia M, Madonna M, Sansone F, Ostacolo C, Capunzo M, Migliarino S, Sciarretta S, Frati G, Campiglia P, Vecchione C.

Hypertension. 2019 Feb;73(2):449-457. doi: 10.1161/HYPERTENSIONAHA.118.11801.

PMID:
30595120
7.

Polyphenolic Extract from Tarocco (Citrus sinensis L. Osbeck) Clone "Lempso" Exerts Anti-Inflammatory and Antioxidant Effects via NF-kB and Nrf-2 Activation in Murine Macrophages.

Pepe G, Sommella E, Cianciarulo D, Ostacolo C, Manfra M, Di Sarno V, Musella S, Russo M, Messore A, Parrino B, Bertamino A, Autore G, Marzocco S, Campiglia P.

Nutrients. 2018 Dec 11;10(12). pii: E1961. doi: 10.3390/nu10121961.

8.

A Novel Small Peptide Inhibitor of NFκB, RH10, Blocks Oxidative Stress-Dependent Phenotypes in Cancer.

Gambardella J, Ciccarelli M, Del Giudice C, Fiordelisi A, De Rosa M, Sala M, Pacelli R, Campiglia P, Trimarco B, Iaccarino G, Sorriento D.

Oxid Med Cell Longev. 2018 Nov 4;2018:5801807. doi: 10.1155/2018/5801807. eCollection 2018.

9.

A Bronze-Tomato Enriched Diet Affects the Intestinal Microbiome under Homeostatic and Inflammatory Conditions.

Liso M, De Santis S, Scarano A, Verna G, Dicarlo M, Galleggiante V, Campiglia P, Mastronardi M, Lippolis A, Vacca M, Sobolewski A, Serino G, Butelli E, De Angelis M, Martin C, Santino A, Chieppa M.

Nutrients. 2018 Dec 2;10(12). pii: E1862. doi: 10.3390/nu10121862.

10.

Annurca Apple Polyphenols Protect Murine Hair Follicles from Taxane Induced Dystrophy and Hijacks Polyunsaturated Fatty Acid Metabolism toward β-Oxidation.

Riccio G, Sommella E, Badolati N, Salviati E, Bottone S, Campiglia P, Dentice M, Tenore GC, Stornaiuolo M, Novellino E.

Nutrients. 2018 Nov 20;10(11). pii: E1808. doi: 10.3390/nu10111808.

11.

Aquaporin 9 Contributes to the Maturation Process and Inflammatory Cytokine Secretion of Murine Dendritic Cells.

De Santis S, Serino G, Fiorentino MR, Galleggiante V, Gena P, Verna G, Liso M, Massaro M, Lan J, Troisi J, Cataldo I, Bertamino A, Pinto A, Campiglia P, Santino A, Giannelli G, Fasano A, Calamita G, Chieppa M.

Front Immunol. 2018 Oct 16;9:2355. doi: 10.3389/fimmu.2018.02355. eCollection 2018. Erratum in: Front Immunol. 2019 Feb 25;10:216.

12.

Annurca Apple Polyphenols Ignite Keratin Production in Hair Follicles by Inhibiting the Pentose Phosphate Pathway and Amino Acid Oxidation.

Badolati N, Sommella E, Riccio G, Salviati E, Heintz D, Bottone S, Di Cicco E, Dentice M, Tenore G, Campiglia P, Stornaiuolo M, Novellino E.

Nutrients. 2018 Oct 2;10(10). pii: E1406. doi: 10.3390/nu10101406.

13.

Investigation on side-product formation during the synthesis of a lactoferrin-derived lactam-bridged cyclic peptide.

Scala MC, Spensiero A, Pepe G, Bertamino A, Carotenuto A, Grieco P, Novellino E, Gomez-Monterrey IM, Campiglia P, Sala M.

Amino Acids. 2018 Oct;50(10):1367-1375. doi: 10.1007/s00726-018-2612-9. Epub 2018 Jul 4.

PMID:
29974257
14.

Antioxidant Properties of Buffalo-Milk Dairy Products: A β-Lg Peptide Released after Gastrointestinal Digestion of Buffalo Ricotta Cheese Reduces Oxidative Stress in Intestinal Epithelial Cells.

Basilicata MG, Pepe G, Adesso S, Ostacolo C, Sala M, Sommella E, Scala MC, Messore A, Autore G, Marzocco S, Campiglia P.

Int J Mol Sci. 2018 Jul 4;19(7). pii: E1955. doi: 10.3390/ijms19071955.

15.

Identification of a Potent Tryptophan-Based TRPM8 Antagonist With in Vivo Analgesic Activity.

Bertamino A, Iraci N, Ostacolo C, Ambrosino P, Musella S, Di Sarno V, Ciaglia T, Pepe G, Sala M, Soldovieri MV, Mosca I, Gonzalez-Rodriguez S, Fernandez-Carvajal A, Ferrer-Montiel A, Novellino E, Taglialatela M, Campiglia P, Gomez-Monterrey I.

J Med Chem. 2018 Jul 26;61(14):6140-6152. doi: 10.1021/acs.jmedchem.8b00545. Epub 2018 Jul 10.

PMID:
29939028
16.

Design, Synthesis, Biological Activity, and Structural Analysis of Lactam-Constrained PTPRJ Agonist Peptides.

Sala M, Spensiero A, Scala MC, Pepe G, Bilotta A, Paduano F, D'Agostino S, Lanzillotta D, Bertamino A, Novellino E, Trapasso F, Gomez-Monterrey IM, Campiglia P.

ChemMedChem. 2018 Aug 20;13(16):1673-1680. doi: 10.1002/cmdc.201800147. Epub 2018 Jul 4.

PMID:
29888867
17.

Fast Profiling of Natural Pigments in Different Spirulina (Arthrospira platensis) Dietary Supplements by DI-FT-ICR and Evaluation of their Antioxidant Potential by Pre-Column DPPH-UHPLC Assay.

Sommella E, Conte GM, Salviati E, Pepe G, Bertamino A, Ostacolo C, Sansone F, Prete FD, Aquino RP, Campiglia P.

Molecules. 2018 May 11;23(5). pii: E1152. doi: 10.3390/molecules23051152.

18.

Innovative Nanoparticles Enhance N-Palmitoylethanolamide Intraocular Delivery.

Puglia C, Blasi P, Ostacolo C, Sommella E, Bucolo C, Platania CBM, Romano GL, Geraci F, Drago F, Santonocito D, Albertini B, Campiglia P, Puglisi G, Pignatello R.

Front Pharmacol. 2018 Mar 28;9:285. doi: 10.3389/fphar.2018.00285. eCollection 2018.

19.

Citrus aurantium L. dry extracts promote C/ebpβ expression and improve adipocyte differentiation in 3T3-L1 cells.

Raciti GA, Fiory F, Campitelli M, Desiderio A, Spinelli R, Longo M, Nigro C, Pepe G, Sommella E, Campiglia P, Formisano P, Beguinot F, Miele C.

PLoS One. 2018 Mar 29;13(3):e0193704. doi: 10.1371/journal.pone.0193704. eCollection 2018.

20.

Peptidome profiles and bioactivity elucidation of buffalo-milk dairy products after gastrointestinal digestion.

Basilicata MG, Pepe G, Sommella E, Ostacolo C, Manfra M, Sosto G, Pagano G, Novellino E, Campiglia P.

Food Res Int. 2018 Mar;105:1003-1010. doi: 10.1016/j.foodres.2017.12.038. Epub 2017 Dec 14.

PMID:
29433190
21.

Chemical profiling of bioactive constituents in hop cones and pellets extracts by online comprehensive two-dimensional liquid chromatography with tandem mass spectrometry and direct infusion Fourier transform ion cyclotron resonance mass spectrometry.

Sommella E, Pagano F, Salviati E, Chieppa M, Bertamino A, Manfra M, Sala M, Novellino E, Campiglia P.

J Sep Sci. 2018 Apr;41(7):1548-1557. doi: 10.1002/jssc.201701242. Epub 2018 Jan 25.

PMID:
29282870
22.

Ring-Fused Cyclic Aminals from Tetrahydro-β-carboline-Based Dipeptide Compounds.

Bertamino A, Lauro G, Ostacolo C, Di Sarno V, Musella S, Ciaglia T, Campiglia P, Bifulco G, Gomez-Monterrey IM.

J Org Chem. 2017 Dec 1;82(23):12014-12027. doi: 10.1021/acs.joc.7b01656. Epub 2017 Nov 14.

PMID:
29091729
23.

Lactoferrin-derived Peptides Active towards Influenza: Identification of Three Potent Tetrapeptide Inhibitors.

Scala MC, Sala M, Pietrantoni A, Spensiero A, Di Micco S, Agamennone M, Bertamino A, Novellino E, Bifulco G, Gomez-Monterrey IM, Superti F, Campiglia P.

Sci Rep. 2017 Sep 6;7(1):10593. doi: 10.1038/s41598-017-10492-x.

24.

TNFα deficiency results in increased IL-1β in an early onset of spontaneous murine colitis.

De Santis S, Kunde D, Galleggiante V, Liso M, Scandiffio L, Serino G, Pinto A, Campiglia P, Sorrentino R, Cavalcanti E, Santino A, Caruso ML, Eri R, Chieppa M.

Cell Death Dis. 2017 Aug 10;8(8):e2993. doi: 10.1038/cddis.2017.397.

25.

Flavonoid Composition of Tarocco (Citrus sinensis L. Osbeck) Clone "Lempso" and Fast Antioxidant Activity Screening by DPPH-UHPLC-PDA-IT-TOF.

Sommella E, Pagano F, Pepe G, Ostacolo C, Manfra M, Chieppa M, Di Sanzo R, Carabetta S, Campiglia P, Russo M.

Phytochem Anal. 2017 Nov;28(6):521-528. doi: 10.1002/pca.2701. Epub 2017 Jul 7.

PMID:
28686312
26.

Secretory Leukoprotease Inhibitor (Slpi) Expression Is Required for Educating Murine Dendritic Cells Inflammatory Response Following Quercetin Exposure.

De Santis S, Galleggiante V, Scandiffio L, Liso M, Sommella E, Sobolewski A, Spilotro V, Pinto A, Campiglia P, Serino G, Santino A, Notarnicola M, Chieppa M.

Nutrients. 2017 Jul 6;9(7). pii: E706. doi: 10.3390/nu9070706.

27.

Urinary Metabolomics in Pediatric Obesity and NAFLD Identifies Metabolic Pathways/Metabolites Related to Dietary Habits and Gut-Liver Axis Perturbations.

Troisi J, Pierri L, Landolfi A, Marciano F, Bisogno A, Belmonte F, Palladino C, Guercio Nuzio S, Campiglia P, Vajro P.

Nutrients. 2017 May 11;9(5). pii: E485. doi: 10.3390/nu9050485.

28.

Bioavailable Citrus sinensis Extract: Polyphenolic Composition and Biological Activity.

Pepe G, Pagano F, Adesso S, Sommella E, Ostacolo C, Manfra M, Chieppa M, Sala M, Russo M, Marzocco S, Campiglia P.

Molecules. 2017 Apr 15;22(4). pii: E623. doi: 10.3390/molecules22040623.

29.

Development of an improved online comprehensive hydrophilic interaction chromatography × reversed-phase ultra-high-pressure liquid chromatography platform for complex multiclass polyphenolic sample analysis.

Sommella E, Ismail OH, Pagano F, Pepe G, Ostacolo C, Mazzoccanti G, Russo M, Novellino E, Gasparrini F, Campiglia P.

J Sep Sci. 2017 May;40(10):2188-2197. doi: 10.1002/jssc.201700134. Epub 2017 Apr 19.

PMID:
28349602
30.

A Healthy Balance of Plasma Cholesterol by a Novel Annurca Apple-Based Nutraceutical Formulation: Results of a Randomized Trial.

Tenore GC, Caruso D, Buonomo G, D'Avino M, Campiglia P, Marinelli L, Novellino E.

J Med Food. 2017 Mar;20(3):288-300. doi: 10.1089/jmf.2016.0152. Epub 2017 Feb 17.

31.

Osteogenesis Is Improved by Low Tumor Necrosis Factor Alpha Concentration through the Modulation of Gs-Coupled Receptor Signals.

Daniele S, Natali L, Giacomelli C, Campiglia P, Novellino E, Martini C, Trincavelli ML.

Mol Cell Biol. 2017 Mar 31;37(8). pii: e00442-16. doi: 10.1128/MCB.00442-16. Print 2017 Apr 15.

32.

Dendritic Cells Modulate Iron Homeostasis and Inflammatory Abilities Following Quercetin Exposure.

Galleggiante V, De Santis S, Cavalcanti E, Scarano A, De Benedictis M, Serino G, Caruso ML, Mastronardi M, Pinto A, Campiglia P, Kunde D, Santino A, Chieppa M.

Curr Pharm Des. 2017;23(14):2139-2146. doi: 10.2174/1381612823666170112125355.

PMID:
28079005
33.

Antioxidant and antimicrobial properties of traditional green and purple "Napoletano" basil cultivars (Ocimum basilicum L.) from Campania region (Italy).

Tenore GC, Campiglia P, Ciampaglia R, Izzo L, Novellino E.

Nat Prod Res. 2017 Sep;31(17):2067-2071. doi: 10.1080/14786419.2016.1269103. Epub 2016 Dec 27.

PMID:
28025898
34.

Cellular subtype expression and activation of CaMKII regulate the fate of atherosclerotic plaque.

Maione AS, Cipolletta E, Sorriento D, Borriello F, Soprano M, Rusciano MR, D'Esposito V, Markabaoui AK, De Palma GD, Martino G, Maresca L, Nobile G, Campiglia P, Formisano P, Ciccarelli M, Marone G, Trimarco B, Iaccarino G, Illario M.

Atherosclerosis. 2017 Jan;256:53-61. doi: 10.1016/j.atherosclerosis.2016.11.006. Epub 2016 Nov 5.

35.

Secretory leukoprotease inhibitor is required for efficient quercetin-mediated suppression of TNFα secretion.

De Santis S, Kunde D, Serino G, Galleggiante V, Caruso ML, Mastronardi M, Cavalcanti E, Ranson N, Pinto A, Campiglia P, Santino A, Eri R, Chieppa M.

Oncotarget. 2016 Nov 15;7(46):75800-75809. doi: 10.18632/oncotarget.12415.

36.

Identification of novel microsomal prostaglandin E2 synthase-1 (mPGES-1) lead inhibitors from Fragment Virtual Screening.

Lauro G, Manfra M, Pedatella S, Fischer K, Cantone V, Terracciano S, Bertamino A, Ostacolo C, Gomez-Monterrey I, De Nisco M, Riccio R, Novellino E, Werz O, Campiglia P, Bifulco G.

Eur J Med Chem. 2017 Jan 5;125:278-287. doi: 10.1016/j.ejmech.2016.09.042. Epub 2016 Sep 14.

PMID:
27688183
37.

Design and Synthesis of New Cell Penetrating Peptides: Diffusion and Distribution Inside the Cornea.

Pescina S, Sala M, Padula C, Scala MC, Spensiero A, Belletti S, Gatti R, Novellino E, Campiglia P, Santi P, Nicoli S, Ostacolo C.

Mol Pharm. 2016 Nov 7;13(11):3876-3883. Epub 2016 Oct 4.

PMID:
27676095
38.

Identification of an indol-based derivative as potent and selective varicella zoster virus (VZV) inhibitor.

Musella S, di Sarno V, Ciaglia T, Sala M, Spensiero A, Scala MC, Ostacolo C, Andrei G, Balzarini J, Snoeck R, Novellino E, Campiglia P, Bertamino A, Gomez-Monterrey IM.

Eur J Med Chem. 2016 Nov 29;124:773-781. doi: 10.1016/j.ejmech.2016.09.014. Epub 2016 Sep 7.

PMID:
27639368
39.

Annurca (Malus pumila Miller cv. Annurca) apple as a functional food for the contribution to a healthy balance of plasma cholesterol levels: results of a randomized clinical trial.

Tenore GC, Caruso D, Buonomo G, D'Urso E, D'Avino M, Campiglia P, Marinelli L, Novellino E.

J Sci Food Agric. 2017 May;97(7):2107-2115. doi: 10.1002/jsfa.8016. Epub 2016 Sep 23.

PMID:
27571713
40.

The 23(rd) National Meeting of the Medicinal Chemistry Division of the Italian Chemical Society (DCF-SCI) in Salerno (NMMC 2015).

Campiglia P, Sbardella G.

ChemMedChem. 2016 Aug 19;11(16):1670-5. doi: 10.1002/cmdc.201600358.

PMID:
27546021
41.

Development and Identification of a Novel Anti-HIV-1 Peptide Derived by Modification of the N-Terminal Domain of HIV-1 Integrase.

Sala M, Spensiero A, Esposito F, Scala MC, Vernieri E, Bertamino A, Manfra M, Carotenuto A, Grieco P, Novellino E, Cadeddu M, Tramontano E, Schols D, Campiglia P, Gomez-Monterrey IM.

Front Microbiol. 2016 Jun 10;7:845. doi: 10.3389/fmicb.2016.00845. eCollection 2016.

42.

Oxidative Stress Mediates the Antiproliferative Effects of Nelfinavir in Breast Cancer Cells.

Soprano M, Sorriento D, Rusciano MR, Maione AS, Limite G, Forestieri P, D'Angelo D, D'Alessio M, Campiglia P, Formisano P, Iaccarino G, Bianco R, Illario M.

PLoS One. 2016 Jun 9;11(6):e0155970. doi: 10.1371/journal.pone.0155970. eCollection 2016.

43.

An Effective Virtual Screening Protocol To Identify Promising p53-MDM2 Inhibitors.

Tortorella P, Laghezza A, Durante M, Gomez-Monterrey I, Bertamino A, Campiglia P, Loiodice F, Daniele S, Martini C, Agamennone M.

J Chem Inf Model. 2016 Jun 27;56(6):1216-27. doi: 10.1021/acs.jcim.5b00747. Epub 2016 Jun 7.

PMID:
27269808
44.

Morus alba extract modulates blood pressure homeostasis through eNOS signaling.

Carrizzo A, Ambrosio M, Damato A, Madonna M, Storto M, Capocci L, Campiglia P, Sommella E, Trimarco V, Rozza F, Izzo R, Puca AA, Vecchione C.

Mol Nutr Food Res. 2016 Oct;60(10):2304-2311. doi: 10.1002/mnfr.201600233. Epub 2016 Jun 27.

PMID:
27234065
45.

A Fhit-mimetic peptide suppresses annexin A4-mediated chemoresistance to paclitaxel in lung cancer cells.

Gaudio E, Paduano F, Ngankeu A, Ortuso F, Lovat F, Pinton S, D'Agostino S, Zanesi N, Aqeilan RI, Campiglia P, Novellino E, Alcaro S, Croce CM, Trapasso F.

Oncotarget. 2016 May 24;7(21):29927-36. doi: 10.18632/oncotarget.9179.

46.

Development of novel cyclic peptides as pro-apoptotic agents.

Brindisi M, Maramai S, Brogi S, Fanigliulo E, Butini S, Guarino E, Casagni A, Lamponi S, Bonechi C, Nathwani SM, Finetti F, Ragonese F, Arcidiacono P, Campiglia P, Valenti S, Novellino E, Spaccapelo R, Morbidelli L, Zisterer DM, Williams CD, Donati A, Baldari C, Campiani G, Ulivieri C, Gemma S.

Eur J Med Chem. 2016 Jul 19;117:301-20. doi: 10.1016/j.ejmech.2016.04.001. Epub 2016 Apr 5.

PMID:
27150036
47.

Structure-Activity Study of the Peptides P5U and Urantide by the Development of Analogues Containing Uncoded Amino Acids at Position 9.

Merlino F, Brancaccio D, Yousif AM, Piras L, Campiglia P, Gomez-Monterrey I, Santicioli P, Meini S, Maggi CA, Novellino E, Carotenuto A, Grieco P.

ChemMedChem. 2016 Aug 19;11(16):1856-64. doi: 10.1002/cmdc.201500607. Epub 2016 Apr 9.

PMID:
27061352
48.

Adipose microenvironment promotes triple negative breast cancer cell invasiveness and dissemination by producing CCL5.

D'Esposito V, Liguoro D, Ambrosio MR, Collina F, Cantile M, Spinelli R, Raciti GA, Miele C, Valentino R, Campiglia P, De Laurentiis M, Di Bonito M, Botti G, Franco R, Beguinot F, Formisano P.

Oncotarget. 2016 Apr 26;7(17):24495-509. doi: 10.18632/oncotarget.8336.

49.

Structure-Based Design of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors using a Virtual Fragment Growing Optimization Scheme.

Lauro G, Tortorella P, Bertamino A, Ostacolo C, Koeberle A, Fischer K, Bruno I, Terracciano S, Gomez-Monterrey IM, Tauro M, Loiodice F, Novellino E, Riccio R, Werz O, Campiglia P, Bifulco G.

ChemMedChem. 2016 Mar 17;11(6):612-9. doi: 10.1002/cmdc.201500598. Epub 2016 Feb 24.

PMID:
26915684
50.

Tryptamine-Based Derivatives as Transient Receptor Potential Melastatin Type 8 (TRPM8) Channel Modulators.

Bertamino A, Ostacolo C, Ambrosino P, Musella S, Di Sarno V, Ciaglia T, Soldovieri MV, Iraci N, Fernandez Carvajal A, de la Torre-Martinez R, Ferrer-Montiel A, Gonzalez Muniz R, Novellino E, Taglialatela M, Campiglia P, Gomez-Monterrey I.

J Med Chem. 2016 Mar 10;59(5):2179-91. doi: 10.1021/acs.jmedchem.5b01914. Epub 2016 Feb 17.

PMID:
26847872

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