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Items: 1 to 50 of 81

1.

Molecular and antigenic characterization of Trypanosoma cruzi TolT proteins.

Lobo M, Balouz V, Melli L, Carlevaro G, Cortina ME, Cámara MLM, Cánepa GE, Carmona SJ, Altcheh J, Campetella O, Ciocchini AE, Agüero F, Mucci J, Buscaglia CA.

PLoS Negl Trop Dis. 2019 Mar 14;13(3):e0007245. doi: 10.1371/journal.pntd.0007245. [Epub ahead of print]

2.

Metabolic Labeling of Surface Neo-sialylglyconjugates Catalyzed by Trypanosoma cruzi trans-Sialidase.

Carlevaro G, Lantos AB, Cánepa GE, de Los Milagros Cámara M, Somoza M, Buscaglia CA, Campetella O, Mucci J.

Methods Mol Biol. 2019;1955:135-146. doi: 10.1007/978-1-4939-9148-8_10.

PMID:
30868524
3.

Interleukin-6 signalling mediates Galectin-8 co-stimulatory activity of antigen-specific CD4 T-cell response.

Carabelli J, Prato CA, Sanmarco LM, Aoki MP, Campetella O, Tribulatti MV.

Immunology. 2018 Nov;155(3):379-386. doi: 10.1111/imm.12980. Epub 2018 Jul 26.

PMID:
29972692
4.

Galectin-3 deficiency drives lupus-like disease by promoting spontaneous germinal centers formation via IFN-γ.

Beccaria CG, Amezcua Vesely MC, Fiocca Vernengo F, Gehrau RC, Ramello MC, Tosello Boari J, Gorosito Serrán M, Mucci J, Piaggio E, Campetella O, Acosta Rodríguez EV, Montes CL, Gruppi A.

Nat Commun. 2018 Apr 24;9(1):1628. doi: 10.1038/s41467-018-04063-5.

5.

Inactive trans-Sialidase Expression in iTS-null Trypanosoma cruzi Generates Virulent Trypomastigotes.

Pascuale CA, Burgos JM, Postan M, Lantos AB, Bertelli A, Campetella O, Leguizamón MS.

Front Cell Infect Microbiol. 2017 Oct 4;7:430. doi: 10.3389/fcimb.2017.00430. eCollection 2017.

6.

Galectin-8 activates dendritic cells and stimulates antigen-specific immune response elicitation.

Carabelli J, Quattrocchi V, D'Antuono A, Zamorano P, Tribulatti MV, Campetella O.

J Leukoc Biol. 2017 Nov;102(5):1237-1247. doi: 10.1189/jlb.3A0816-357RR. Epub 2017 Aug 15.

PMID:
28811319
7.

The Trypomastigote Small Surface Antigen (TSSA) regulates Trypanosoma cruzi infectivity and differentiation.

Cámara MLM, Cánepa GE, Lantos AB, Balouz V, Yu H, Chen X, Campetella O, Mucci J, Buscaglia CA.

PLoS Negl Trop Dis. 2017 Aug 11;11(8):e0005856. doi: 10.1371/journal.pntd.0005856. eCollection 2017 Aug.

8.

The Trypanosoma cruzi Surface, a Nanoscale Patchwork Quilt.

Mucci J, Lantos AB, Buscaglia CA, Leguizamón MS, Campetella O.

Trends Parasitol. 2017 Feb;33(2):102-112. doi: 10.1016/j.pt.2016.10.004. Epub 2016 Nov 11. Review.

9.

Sialic Acid Glycobiology Unveils Trypanosoma cruzi Trypomastigote Membrane Physiology.

Lantos AB, Carlevaro G, Araoz B, Ruiz Diaz P, Camara Mde L, Buscaglia CA, Bossi M, Yu H, Chen X, Bertozzi CR, Mucci J, Campetella O.

PLoS Pathog. 2016 Apr 8;12(4):e1005559. doi: 10.1371/journal.ppat.1005559. eCollection 2016 Apr.

10.

Characterization of a double-CRD-mutated Gal-8 recombinant protein that retains co-stimulatory activity on antigen-specific T-cell response.

Schroeder MN, Tribulatti MV, Carabelli J, André-Leroux G, Caramelo JJ, Cattaneo V, Campetella O.

Biochem J. 2016 Apr 1;473(7):887-98. doi: 10.1042/BJ20150409. Epub 2016 Jan 21.

PMID:
26795039
11.

Towards High-throughput Immunomics for Infectious Diseases: Use of Next-generation Peptide Microarrays for Rapid Discovery and Mapping of Antigenic Determinants.

Carmona SJ, Nielsen M, Schafer-Nielsen C, Mucci J, Altcheh J, Balouz V, Tekiel V, Frasch AC, Campetella O, Buscaglia CA, Agüero F.

Mol Cell Proteomics. 2015 Jul;14(7):1871-84. doi: 10.1074/mcp.M114.045906. Epub 2015 Apr 28.

12.

Trypanosoma cruzi trans-sialidase prevents elicitation of Th1 cell response via interleukin 10 and downregulates Th1 effector cells.

Ruiz Díaz P, Mucci J, Meira MA, Bogliotti Y, Musikant D, Leguizamón MS, Campetella O.

Infect Immun. 2015 May;83(5):2099-108. doi: 10.1128/IAI.00031-15. Epub 2015 Mar 9.

13.

Rab11 regulates trafficking of trans-sialidase to the plasma membrane through the contractile vacuole complex of Trypanosoma cruzi.

Niyogi S, Mucci J, Campetella O, Docampo R.

PLoS Pathog. 2014 Jun 26;10(6):e1004224. doi: 10.1371/journal.ppat.1004224. eCollection 2014 Jun.

14.

Galectin-8 elicits pro-inflammatory activities in the endothelium.

Cattaneo V, Tribulatti MV, Carabelli J, Carestia A, Schattner M, Campetella O.

Glycobiology. 2014 Oct;24(10):966-73. doi: 10.1093/glycob/cwu060. Epub 2014 Jun 22.

PMID:
24957054
15.

Control of angiogenesis by galectins involves the release of platelet-derived proangiogenic factors.

Etulain J, Negrotto S, Tribulatti MV, Croci DO, Carabelli J, Campetella O, Rabinovich GA, Schattner M.

PLoS One. 2014 Apr 30;9(4):e96402. doi: 10.1371/journal.pone.0096402. eCollection 2014.

16.

Trypanosoma cruzi trans-sialidase initiates a program independent of the transcription factors RORγt and Ahr that leads to IL-17 production by activated B cells.

Bermejo DA, Jackson SW, Gorosito-Serran M, Acosta-Rodriguez EV, Amezcua-Vesely MC, Sather BD, Singh AK, Khim S, Mucci J, Liggitt D, Campetella O, Oukka M, Gruppi A, Rawlings DJ.

Nat Immunol. 2013 May;14(5):514-22. doi: 10.1038/ni.2569. Epub 2013 Apr 7.

17.

Differential distribution of genes encoding the virulence factor trans-sialidase along Trypanosoma cruzi Discrete typing units.

Burgos JM, Risso MG, Brenière SF, Barnabé C, Campetella O, Leguizamón MS.

PLoS One. 2013;8(3):e58967. doi: 10.1371/journal.pone.0058967. Epub 2013 Mar 11.

18.

Diagnostic peptide discovery: prioritization of pathogen diagnostic markers using multiple features.

Carmona SJ, Sartor PA, Leguizamón MS, Campetella OE, Agüero F.

PLoS One. 2012;7(12):e50748. doi: 10.1371/journal.pone.0050748. Epub 2012 Dec 14.

19.

Binding of galectin-1 to αIIbβ₃ integrin triggers "outside-in" signals, stimulates platelet activation, and controls primary hemostasis.

Romaniuk MA, Croci DO, Lapponi MJ, Tribulatti MV, Negrotto S, Poirier F, Campetella O, Rabinovich GA, Schattner M.

FASEB J. 2012 Jul;26(7):2788-98. doi: 10.1096/fj.11-197541. Epub 2012 Mar 27.

PMID:
22456341
20.

Redundant and antagonistic functions of galectin-1, -3, and -8 in the elicitation of T cell responses.

Tribulatti MV, Figini MG, Carabelli J, Cattaneo V, Campetella O.

J Immunol. 2012 Apr 1;188(7):2991-9. doi: 10.4049/jimmunol.1102182. Epub 2012 Feb 22.

21.

Trypanosoma cruzi trans-sialidase in complex with a neutralizing antibody: structure/function studies towards the rational design of inhibitors.

Buschiazzo A, Muiá R, Larrieux N, Pitcovsky T, Mucci J, Campetella O.

PLoS Pathog. 2012 Jan;8(1):e1002474. doi: 10.1371/journal.ppat.1002474. Epub 2012 Jan 5.

22.

Identification of galectins as novel regulators of platelet signaling and function.

Romaniuk MA, Negrotto S, Campetella O, Rabinovich GA, Schattner M.

IUBMB Life. 2011 Jul;63(7):521-7. doi: 10.1002/iub.483. Review.

23.

Galectin-8 tandem-repeat structure is essential for T-cell proliferation but not for co-stimulation.

Cattaneo V, Tribulatti MV, Campetella O.

Biochem J. 2011 Feb 15;434(1):153-60. doi: 10.1042/BJ20101691.

PMID:
21091438
24.

Human platelets express and are activated by galectin-8.

Romaniuk MA, Tribulatti MV, Cattaneo V, Lapponi MJ, Molinas FC, Campetella O, Schattner M.

Biochem J. 2010 Dec 15;432(3):535-47. doi: 10.1042/BJ20100538.

PMID:
20858220
25.

Continuous nonradioactive method for screening trypanosomal trans-sialidase activity and its inhibitors.

Sartor PA, Agusti R, Leguizamón MS, Campetella O, de Lederkremer RM.

Glycobiology. 2010 Aug;20(8):982-90. doi: 10.1093/glycob/cwq056. Epub 2010 Apr 7.

26.

Identification of glycoproteins targeted by Trypanosoma cruzi trans-sialidase, a virulence factor that disturbs lymphocyte glycosylation.

Muiá RP, Yu H, Prescher JA, Hellman U, Chen X, Bertozzi CR, Campetella O.

Glycobiology. 2010 Jul;20(7):833-42. doi: 10.1093/glycob/cwq037. Epub 2010 Mar 30.

27.

Galectin-8 provides costimulatory and proliferative signals to T lymphocytes.

Tribulatti MV, Cattaneo V, Hellman U, Mucci J, Campetella O.

J Leukoc Biol. 2009 Aug;86(2):371-80. doi: 10.1189/jlb.0908529. Epub 2009 Apr 28.

PMID:
19401394
28.

Stage-specific expression of Trypanosoma cruzi trans-sialidase involves highly conserved 3' untranslated regions.

Jäger AV, Muiá RP, Campetella O.

FEMS Microbiol Lett. 2008 Jun;283(2):182-8. doi: 10.1111/j.1574-6968.2008.01170.x. Epub 2008 Apr 16.

29.

Galectin-8 induces apoptosis in the CD4(high)CD8(high) thymocyte subpopulation.

Tribulatti MV, Mucci J, Cattaneo V, Agüero F, Gilmartin T, Head SR, Campetella O.

Glycobiology. 2007 Dec;17(12):1404-12. Epub 2007 Sep 24.

PMID:
17893094
30.

Immune system pathogenesis is prevented by the neutralization of the systemic trans-sialidase from Trypanosoma cruzi during severe infections.

Risso MG, Pitcovsky TA, Caccuri RL, Campetella O, Leguizamón MS.

Parasitology. 2007 Apr;134(Pt 4):503-10. Epub 2006 Dec 14.

PMID:
17166319
31.

The trans-sialidase from Trypanosoma cruzi triggers apoptosis by target cell sialylation.

Mucci J, Risso MG, Leguizamón MS, Frasch AC, Campetella O.

Cell Microbiol. 2006 Jul;8(7):1086-95.

PMID:
16819962
32.

A Trypanosoma cruzi antigen signals CD11b+ cells to secrete cytokines that promote polyclonal B cell proliferation and differentiation into antibody-secreting cells.

Montes CL, Acosta-Rodríguez EV, Mucci J, Zuniga EI, Campetella O, Gruppi A.

Eur J Immunol. 2006 Jun;36(6):1474-85.

33.

A sexual dimorphism in intrathymic sialylation survey is revealed by the trans-sialidase from Trypanosoma cruzi.

Mucci J, Mocetti E, Leguizamón MS, Campetella O.

J Immunol. 2005 Apr 15;174(8):4545-50.

34.

The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas' disease by reducing the platelet sialic acid contents.

Tribulatti MV, Mucci J, Van Rooijen N, Leguizamón MS, Campetella O.

Infect Immun. 2005 Jan;73(1):201-7.

35.

Differential expression of a virulence factor, the trans-sialidase, by the main Trypanosoma cruzi phylogenetic lineages.

Risso MG, Garbarino GB, Mocetti E, Campetella O, Gonzalez Cappa SM, Buscaglia CA, Leguizamon MS.

J Infect Dis. 2004 Jun 15;189(12):2250-9. Epub 2004 May 25.

PMID:
15181573
36.

Improving protein pharmacokinetics by genetic fusion to simple amino acid sequences.

Alvarez P, Buscaglia CA, Campetella O.

J Biol Chem. 2004 Jan 30;279(5):3375-81. Epub 2003 Nov 11.

37.

A functional network of intramolecular cross-reacting epitopes delays the elicitation of neutralizing antibodies to Trypanosoma cruzi trans-sialidase.

Pitcovsky TA, Buscaglia CA, Mucci J, Campetella O.

J Infect Dis. 2002 Aug 1;186(3):397-404. Epub 2002 Jul 17.

PMID:
12134236
38.

Thymocyte depletion in Trypanosoma cruzi infection is mediated by trans-sialidase-induced apoptosis on nurse cells complex.

Mucci J, Hidalgo A, Mocetti E, Argibay PF, Leguizamon MS, Campetella O.

Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3896-901. Epub 2002 Mar 12.

39.

Multiple overlapping epitopes in the repetitive unit of the shed acute-phase antigen from Trypanosoma cruzi enhance its immunogenic properties.

Alvarez P, Leguizamón MS, Buscaglia CA, Pitcovsky TA, Campetella O.

Infect Immun. 2001 Dec;69(12):7946-9.

40.

Epitope mapping of trans-sialidase from Trypanosoma cruzi reveals the presence of several cross-reactive determinants.

Pitcovsky TA, Mucci J, Alvarez P, Leguizamón MS, Burrone O, Alzari PM, Campetella O.

Infect Immun. 2001 Mar;69(3):1869-75.

41.

trans-sialidase inhibition assay, a highly sensitive and specific diagnostic test for Chagas' disease.

Buchovsky AS, Campetella O, Russomando G, Franco L, Oddone R, Candia N, Luquetti A, Gonzalez Cappa SM, Leguizamon MS.

Clin Diagn Lab Immunol. 2001 Jan;8(1):187-9.

42.

Structural basis of sialyltransferase activity in trypanosomal sialidases.

Buschiazzo A, Tavares GA, Campetella O, Spinelli S, Cremona ML, París G, Amaya MF, Frasch AC, Alzari PM.

EMBO J. 2000 Jan 4;19(1):16-24.

43.

Trans-sialidase from Trypanosoma cruzi induces apoptosis in cells from the immune system in vivo.

Leguizamón MS, Mocetti E, García Rivello H, Argibay P, Campetella O.

J Infect Dis. 1999 Oct;180(4):1398-402.

PMID:
10479182
44.

Enzymically inactive members of the trans-sialidase family from Trypanosoma cruzi display beta-galactose binding activity.

Cremona ML, Campetella O, Sánchez DO, Frasch AC.

Glycobiology. 1999 Jun;9(6):581-7.

PMID:
10336990
45.

Tandem amino acid repeats from Trypanosoma cruzi shed antigens increase the half-life of proteins in blood.

Buscaglia CA, Alfonso J, Campetella O, Frasch AC.

Blood. 1999 Mar 15;93(6):2025-32.

46.

Structure of the glycosylphosphatidylinositol-anchor of the trans-sialidase from Trypanosoma cruzi metacyclic trypomastigote forms.

Agusti R, Couto AS, Campetella O, Frasch AC, de Lederkremer RM.

Mol Biochem Parasitol. 1998 Nov 30;97(1-2):123-31.

PMID:
9879892
47.

The NADP+-linked glutamate dehydrogenase from Trypanosoma cruzi: sequence, genomic organization and expression.

Barderi P, Campetella O, Frasch AC, Santomé JA, Hellman U, Pettersson U, Cazzulo JJ.

Biochem J. 1998 Mar 1;330 ( Pt 2):951-8.

48.

Use of trans-Sialidase inhibition assay in a population serologically negative for Trypanosoma cruzi but at a high risk of infection.

Leguizamón MS, Russomando G, Rojas de Arias A, Samudio M, Cabral M, González-Cappa SM, Frasch AC, Campetella O.

Clin Diagn Lab Immunol. 1998 Mar;5(2):254-5.

49.

The repetitive domain of Trypanosoma cruzi trans-sialidase enhances the immune response against the catalytic domain.

Buscaglia CA, Campetella O, Leguizamón MS, Frasch AC.

J Infect Dis. 1998 Feb;177(2):431-6.

PMID:
9466532
50.

Trypanosoma rangeli sialidase: cloning, expression and similarity to T. cruzi trans-sialidase.

Buschiazzo A, Campetella O, Frasch AC.

Glycobiology. 1997 Dec;7(8):1167-73.

PMID:
9455917

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