Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 146


Structural basis for transcription activation by Crl through tethering of σS and RNA polymerase.

Cartagena AJ, Banta AB, Sathyan N, Ross W, Gourse RL, Campbell EA, Darst SA.

Proc Natl Acad Sci U S A. 2019 Sep 17;116(38):18923-18927. doi: 10.1073/pnas.1910827116. Epub 2019 Sep 4.


Preclinical toxicology and safety pharmacology of the first-in-class GADD45β/MKK7 inhibitor and clinical candidate, DTP3.

Tornatore L, Capece D, D'Andrea D, Begalli F, Verzella D, Bennett J, Acton G, Campbell EA, Kelly J, Tarbit M, Adams N, Bannoo S, Leonardi A, Sandomenico A, Raimondo D, Ruvo M, Chambery A, Oblak M, Al-Obaidi MJ, Kaczmarski RS, Gabriel I, Oakervee HE, Kaiser MF, Wechalekar A, Benjamin R, Apperley JF, Auner HW, Franzoso G.

Toxicol Rep. 2019 Apr 19;6:369-379. doi: 10.1016/j.toxrep.2019.04.006. eCollection 2019.


Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding.

Boyaci H, Chen J, Jansen R, Darst SA, Campbell EA.

Nature. 2019 Jan;565(7739):382-385. doi: 10.1038/s41586-018-0840-5. Epub 2019 Jan 9.


Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin.

Braffman NR, Piscotta FJ, Hauver J, Campbell EA, Link AJ, Darst SA.

Proc Natl Acad Sci U S A. 2019 Jan 22;116(4):1273-1278. doi: 10.1073/pnas.1817352116. Epub 2019 Jan 9.


Bowel Necrosis.

Campbell EA, Silberman M.

StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019 Jan-.
2019 Jan 13.


Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism.

Peek J, Lilic M, Montiel D, Milshteyn A, Woodworth I, Biggins JB, Ternei MA, Calle PY, Danziger M, Warrier T, Saito K, Braffman N, Fay A, Glickman MS, Darst SA, Campbell EA, Brady SF.

Nat Commun. 2018 Oct 8;9(1):4147. doi: 10.1038/s41467-018-06587-2.


Clinical proof of concept for a safe and effective NF-κB-targeting strategy in multiple myeloma.

Tornatore L, Capece D, D'Andrea D, Begalli F, Verzella D, Bennett J, Acton G, Campbell EA, Kelly J, Tarbit M, Adams N, Bannoo S, Leonardi A, Sandomenico A, Raimondo D, Ruvo M, Chambery A, Oblak M, Al-Obaidi MJ, Kaczmarski RS, Gabriel I, Oakervee HE, Kaiser MF, Wechalekar A, Benjamin R, Apperley JF, Auner HW, Franzoso G.

Br J Haematol. 2019 May;185(3):588-592. doi: 10.1111/bjh.15569. Epub 2018 Sep 26. No abstract available.


Fidaxomicin jams Mycobacterium tuberculosis RNA polymerase motions needed for initiation via RbpA contacts.

Boyaci H, Chen J, Lilic M, Palka M, Mooney RA, Landick R, Darst SA, Campbell EA.

Elife. 2018 Feb 26;7. pii: e34823. doi: 10.7554/eLife.34823.


Foreign Body Imaging.

Campbell EA, Wilbert CD.

StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019 Jan-.
2019 Apr 30.


Healthy Food Availability Among Food Sources in Rural Maryland Counties.

Campbell EA, Shapiro MJ, Welsh C, Bleich SN, Cobb LK, Gittelsohn J.

J Hunger Environ Nutr. 2017;12(3):328-341. doi: 10.1080/19320248.2017.1315328. Epub 2017 Jun 8.


6S RNA Mimics B-Form DNA to Regulate Escherichia coli RNA Polymerase.

Chen J, Wassarman KM, Feng S, Leon K, Feklistov A, Winkelman JT, Li Z, Walz T, Campbell EA, Darst SA.

Mol Cell. 2017 Oct 19;68(2):388-397.e6. doi: 10.1016/j.molcel.2017.09.006. Epub 2017 Oct 5.


Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures.

Hubin EA, Lilic M, Darst SA, Campbell EA.

Nat Commun. 2017 Jul 13;8:16072. doi: 10.1038/ncomms16072.


Structural basis of transcription arrest by coliphage HK022 Nun in an Escherichia coli RNA polymerase elongation complex.

Kang JY, Olinares PD, Chen J, Campbell EA, Mustaev A, Chait BT, Gottesman ME, Darst SA.

Elife. 2017 Mar 20;6. pii: e25478. doi: 10.7554/eLife.25478.


Autism Spectrum Disorder in a Community-based Sample with Neurodevelopmental Problems in Lagos, Nigeria.

Oshodi YO, Olagunju AT, Oyelohunnu MA, Campbell EA, Umeh CS, Aina OF, Oyibo W, Lesi FE, Adeyemi JD.

J Public Health Afr. 2017 Jan 17;7(2):559. doi: 10.4081/jphia.2016.559. eCollection 2016 Dec 31.


Self-Assembling Molecular Logic Gates Based on DNA Crossover Tiles.

Campbell EA, Peterson E, Kolpashchikov DM.

Chemphyschem. 2017 Jul 5;18(13):1730-1734. doi: 10.1002/cphc.201700109. Epub 2017 Mar 24.


Crystal structure of Aquifex aeolicus σN bound to promoter DNA and the structure of σN-holoenzyme.

Campbell EA, Kamath S, Rajashankar KR, Wu M, Darst SA.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):E1805-E1814. doi: 10.1073/pnas.1619464114. Epub 2017 Feb 21.


Structure and function of the mycobacterial transcription initiation complex with the essential regulator RbpA.

Hubin EA, Fay A, Xu C, Bean JM, Saecker RM, Glickman MS, Darst SA, Campbell EA.

Elife. 2017 Jan 9;6. pii: e22520. doi: 10.7554/eLife.22520.


Effects of Increasing the Affinity of CarD for RNA Polymerase on Mycobacterium tuberculosis Growth, rRNA Transcription, and Virulence.

Garner AL, Rammohan J, Huynh JP, Onder LM, Chen J, Bae B, Jensen D, Weiss LA, Manzano AR, Darst SA, Campbell EA, Nickels BE, Galburt EA, Stallings CL.

J Bacteriol. 2017 Jan 30;199(4). pii: e00698-16. doi: 10.1128/JB.00698-16. Print 2017 Feb 15.


Diabetes Quality of Care Before and After Implementation of a Resident Clinic Practice Partnership System.

Campbell EA, Crowley MJ, Powers BJ, Sanders LL, Olsen MK, Danus S, McNeill DB, Zaas AK.

Am J Med Qual. 2017 Jan/Feb;32(1):66-72. doi: 10.1177/1062860615615210. Epub 2016 Jul 10.


Oral health needs in individuals with trisomy 18 and trisomy 13: Implications for dental professionals.

Bruns D, Martinez A, Campbell EA.

Spec Care Dentist. 2016 Jan;36(1):18-24. doi: 10.1111/scd.12146. Epub 2015 Nov 20.


CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex.

Bae B, Chen J, Davis E, Leon K, Darst SA, Campbell EA.

Elife. 2015 Sep 8;4. doi: 10.7554/eLife.08505.


Structural, functional, and genetic analyses of the actinobacterial transcription factor RbpA.

Hubin EA, Tabib-Salazar A, Humphrey LJ, Flack JE, Olinares PD, Darst SA, Campbell EA, Paget MS.

Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7171-6. doi: 10.1073/pnas.1504942112. Epub 2015 May 26.


Impact of emotional distress on caregivers burden among Nigerian children with Obstructive Adenotonsillar hypertrophy.

Olagunju AT, Asoegwu CN, Campbell EA, Akinbode AA, Aina OF, Nwawolo CC.

Int J Pediatr Otorhinolaryngol. 2015 Jun;79(6):858-62. doi: 10.1016/j.ijporl.2015.03.018. Epub 2015 Mar 28.


Interplay of anxiety and depression with quality of life in endstage renal disease.

Olagunju AT, Campbell EA, Adeyemi JD.

Psychosomatics. 2015 Jan-Feb;56(1):67-77. doi: 10.1016/j.psym.2014.03.006. Epub 2014 Mar 26.


Mycobacterial RNA polymerase forms unstable open promoter complexes that are stabilized by CarD.

Davis E, Chen J, Leon K, Darst SA, Campbell EA.

Nucleic Acids Res. 2015 Jan;43(1):433-45. doi: 10.1093/nar/gku1231. Epub 2014 Dec 15.


Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of σ70 domain 1.1.

Bae B, Davis E, Brown D, Campbell EA, Wigneshweraraj S, Darst SA.

Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19772-7. doi: 10.1073/pnas.1314576110. Epub 2013 Nov 11.


Key features of σS required for specific recognition by Crl, a transcription factor promoting assembly of RNA polymerase holoenzyme.

Banta AB, Chumanov RS, Yuan AH, Lin H, Campbell EA, Burgess RR, Gourse RL.

Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):15955-60. doi: 10.1073/pnas.1311642110. Epub 2013 Sep 16.


Access to the Commonwealth electoral roll for medical research.

Loff B, Campbell EA, Glass DC, Kelsall HL, Slegers C, Zion DR, Brown NJ, Fritschi L.

Med J Aust. 2013 Jul 22;199(2):128-30.


Structure and function of CarD, an essential mycobacterial transcription factor.

Srivastava DB, Leon K, Osmundson J, Garner AL, Weiss LA, Westblade LF, Glickman MS, Landick R, Darst SA, Stallings CL, Campbell EA.

Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):12619-24. doi: 10.1073/pnas.1308270110. Epub 2013 Jul 15.


Interaction of CarD with RNA polymerase mediates Mycobacterium tuberculosis viability, rifampin resistance, and pathogenesis.

Weiss LA, Harrison PG, Nickels BE, Glickman MS, Campbell EA, Darst SA, Stallings CL.

J Bacteriol. 2012 Oct;194(20):5621-31. Epub 2012 Aug 17.


Molecular logic gates for DNA analysis: detection of rifampin resistance in M. tuberculosis DNA.

Cornett EM, Campbell EA, Gulenay G, Peterson E, Bhaskar N, Kolpashchikov DM.

Angew Chem Int Ed Engl. 2012 Sep 3;51(36):9075-7. doi: 10.1002/anie.201203708. Epub 2012 Aug 9.


A study on epidemiological profile of anxiety disorders among people living with HIV/AIDS in a sub-Saharan Africa HIV clinic.

Olagunju AT, Adeyemi JD, Ogbolu RE, Campbell EA.

AIDS Behav. 2012 Nov;16(8):2192-7. doi: 10.1007/s10461-012-0250-x.


Crystal structure of the bacteriophage T4 late-transcription coactivator gp33 with the β-subunit flap domain of Escherichia coli RNA polymerase.

Twist KA, Campbell EA, Deighan P, Nechaev S, Jain V, Geiduschek EP, Hochschild A, Darst SA.

Proc Natl Acad Sci U S A. 2011 Dec 13;108(50):19961-6. doi: 10.1073/pnas.1113328108. Epub 2011 Dec 1.


A novel method for the production of in vivo-assembled, recombinant Escherichia coli RNA polymerase lacking the α C-terminal domain.

Twist KA, Husnain SI, Franke JD, Jain D, Campbell EA, Nickels BE, Thomas MS, Darst SA, Westblade LF.

Protein Sci. 2011 Jun;20(6):986-95. doi: 10.1002/pro.622. Epub 2011 Apr 26.


Structural basis for the bacterial transcription-repair coupling factor/RNA polymerase interaction.

Westblade LF, Campbell EA, Pukhrambam C, Padovan JC, Nickels BE, Lamour V, Darst SA.

Nucleic Acids Res. 2010 Dec;38(22):8357-69. doi: 10.1093/nar/gkq692. Epub 2010 Aug 11.


Insights into antiparallel microtubule crosslinking by PRC1, a conserved nonmotor microtubule binding protein.

Subramanian R, Wilson-Kubalek EM, Arthur CP, Bick MJ, Campbell EA, Darst SA, Milligan RA, Kapoor TM.

Cell. 2010 Aug 6;142(3):433-43. doi: 10.1016/j.cell.2010.07.012.


Utilization of variably spaced promoter-like elements by the bacterial RNA polymerase holoenzyme during early elongation.

Devi PG, Campbell EA, Darst SA, Nickels BE.

Mol Microbiol. 2010 Feb;75(3):607-22. doi: 10.1111/j.1365-2958.2009.07021.x. Epub 2010 Jan 12.


Crystal structure of the in vivo-assembled Bacillus subtilis Spx/RNA polymerase alpha subunit C-terminal domain complex.

Lamour V, Westblade LF, Campbell EA, Darst SA.

J Struct Biol. 2009 Nov;168(2):352-6. doi: 10.1016/j.jsb.2009.07.001. Epub 2009 Jul 4.


Dissection of recognition determinants of Escherichia coli sigma32 suggests a composite -10 region with an 'extended -10' motif and a core -10 element.

Koo BM, Rhodius VA, Campbell EA, Gross CA.

Mol Microbiol. 2009 May;72(4):815-29. doi: 10.1111/j.1365-2958.2009.06690.x. Epub 2009 Apr 14.


Mutational analysis of Escherichia coli sigma28 and its target promoters reveals recognition of a composite -10 region, comprised of an 'extended -10' motif and a core -10 element.

Koo BM, Rhodius VA, Campbell EA, Gross CA.

Mol Microbiol. 2009 May;72(4):830-43. doi: 10.1111/j.1365-2958.2009.06691.x. Epub 2009 Apr 14.


Regulation of bacterial RNA polymerase sigma factor activity: a structural perspective.

Campbell EA, Westblade LF, Darst SA.

Curr Opin Microbiol. 2008 Apr;11(2):121-7. doi: 10.1016/j.mib.2008.02.016. Epub 2008 Mar 28. Review.


A conserved structural module regulates transcriptional responses to diverse stress signals in bacteria.

Campbell EA, Greenwell R, Anthony JR, Wang S, Lim L, Das K, Sofia HJ, Donohue TJ, Darst SA.

Mol Cell. 2007 Sep 7;27(5):793-805.


Crystal structure of the Escherichia coli regulator of sigma70, Rsd, in complex with sigma70 domain 4.

Patikoglou GA, Westblade LF, Campbell EA, Lamour V, Lane WJ, Darst SA.

J Mol Biol. 2007 Sep 21;372(3):649-59. Epub 2007 Jul 3.


Temporal expression profiling of the uterine luminal epithelium of the pseudo-pregnant mouse suggests receptivity to the fertilized egg is associated with complex transcriptional changes.

Campbell EA, O'Hara L, Catalano RD, Sharkey AM, Freeman TC, Johnson MH.

Hum Reprod. 2006 Oct;21(10):2495-513. Epub 2006 Jun 21.


Developmental and reproductive performance in circadian mutant mice.

Dolatshad H, Campbell EA, O'Hara L, Maywood ES, Hastings MH, Johnson MH.

Hum Reprod. 2006 Jan;21(1):68-79. Epub 2005 Oct 6.


Inhibition of Stat3 activation in the endometrium prevents implantation: a nonsteroidal approach to contraception.

Catalano RD, Johnson MH, Campbell EA, Charnock-Jones DS, Smith SK, Sharkey AM.

Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8585-90. Epub 2005 Jun 3.


Bipolar disorder in older adult inpatients.

Sajatovic M, Bingham CR, Campbell EA, Fletcher DF.

J Nerv Ment Dis. 2005 Jun;193(6):417-9.


Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase.

Campbell EA, Pavlova O, Zenkin N, Leon F, Irschik H, Jansen R, Severinov K, Darst SA.

EMBO J. 2005 Feb 23;24(4):674-82. Epub 2005 Feb 3.


Muslim culture and female self-immolation: implications for global women's health research and practice.

Campbell EA, Guiao IZ.

Health Care Women Int. 2004 Oct;25(9):782-93. Review.


Crystal structures of the ADP and ATP bound forms of the Bacillus anti-sigma factor SpoIIAB in complex with the anti-anti-sigma SpoIIAA.

Masuda S, Murakami KS, Wang S, Anders Olson C, Donigian J, Leon F, Darst SA, Campbell EA.

J Mol Biol. 2004 Jul 23;340(5):941-56.


Supplemental Content

Loading ...
Support Center