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Items: 1 to 50 of 97

1.

Alamandine attenuates arterial remodelling induced by transverse aortic constriction in mice.

de Souza-Neto FP, Silva MME, Santuchi MC, de Alcântara-Leonídio TC, Motta-Santos D, Oliveira AC, Melo MB, Canta GN, de Souza LE, Irigoyen MCC, Campagnole-Santos MJ, Guatimosim S, Santos RAS, da Silva RF.

Clin Sci (Lond). 2019 Mar 1;133(5):629-643. doi: 10.1042/CS20180547. Print 2019 Mar 15.

PMID:
30737255
2.

Genetic deletion of the alamandine receptor MRGD leads to dilated cardiomyopathy in mice.

Oliveira AC, Melo MB, Motta-Santos D, Peluso AA, Souza-Neto F, da Silva RF, Almeida JFQ, Canta G, Reis AM, Goncalves G, Cerri G, Coutinho D, Guedes de Jesus IC, Guatimosim S, Linhares ND, Alenina N, Bader M, Campagnole-Santos MJ, Santos RAS.

Am J Physiol Heart Circ Physiol. 2019 Jan 1;316(1):H123-H133. doi: 10.1152/ajpheart.00075.2018. Epub 2018 Oct 19.

PMID:
30339496
3.

The usefulness of short-term high-fat/high salt diet as a model of metabolic syndrome in mice.

Mendes-Junior LG, Freitas-Lima LC, Oliveira JR, Melo MB, Feltenberger JD, Brandi IV, Carvalho BMA, Guimarães ALS, De Paula AMB, D'Angelis CEM, Campagnole-Santos MJ, Souza Santos RA, Braga VA, Santos SHS.

Life Sci. 2018 Sep 15;209:341-348. doi: 10.1016/j.lfs.2018.08.034. Epub 2018 Aug 14.

PMID:
30118771
4.

Eccentric Overload Muscle Damage is Attenuated By a Novel Angiotensin- (1-7) Treatment.

Becker LK, Totou N, Moura S, Kangussu L, Millán RDS, Campagnole-Santos MJ, Coelho D, Motta-Santos D, Santos RAS.

Int J Sports Med. 2018 Oct;39(10):743-748. doi: 10.1055/a-0633-8892. Epub 2018 Jun 25.

PMID:
29940668
5.

Physical training improves thermogenesis and insulin pathway, and induces remodeling in white and brown adipose tissues.

Barbosa MA, Guerra-Sá R, De Castro UGM, de Lima WG, Dos Santos RAS, Campagnole-Santos MJ, Alzamora AC.

J Physiol Biochem. 2018 Aug;74(3):441-454. doi: 10.1007/s13105-018-0637-x. Epub 2018 May 25.

PMID:
29797227
6.

Angiotensin-(1-7) reduces cardiac effects of thyroid hormone by GSK3Β/NFATc3 signaling pathway.

Senger N, Melo MB, Diniz GP, Campagnole-Santos MJ, Santos RAS, Barreto-Chaves MLM.

Clin Sci (Lond). 2018 Jun 5;132(11):1117-1133. doi: 10.1042/CS20171606. Print 2018 Jun 14.

PMID:
29685981
7.

Angiotensin-(1-7) and Alamandine on Experimental Models of Hypertension and Atherosclerosis.

de Souza-Neto FP, Carvalho Santuchi M, de Morais E Silva M, Campagnole-Santos MJ, da Silva RF.

Curr Hypertens Rep. 2018 Mar 14;20(2):17. doi: 10.1007/s11906-018-0798-6. Review.

PMID:
29541937
8.

Angiotensin-(1-7) Promotes Resolution of Eosinophilic Inflammation in an Experimental Model of Asthma.

Magalhaes GS, Barroso LC, Reis AC, Rodrigues-Machado MG, Gregório JF, Motta-Santos D, Oliveira AC, Perez DA, Barcelos LS, Teixeira MM, Santos RAS, Pinho V, Campagnole-Santos MJ.

Front Immunol. 2018 Jan 29;9:58. doi: 10.3389/fimmu.2018.00058. eCollection 2018.

9.

The ACE2/Angiotensin-(1-7)/MAS Axis of the Renin-Angiotensin System: Focus on Angiotensin-(1-7).

Santos RAS, Sampaio WO, Alzamora AC, Motta-Santos D, Alenina N, Bader M, Campagnole-Santos MJ.

Physiol Rev. 2018 Jan 1;98(1):505-553. doi: 10.1152/physrev.00023.2016. Review.

10.

GABA-containing liposomes: neuroscience applications and translational perspectives for targeting neurological diseases.

Fontes MAP, Vaz GC, Cardoso TZD, de Oliveira MF, Campagnole-Santos MJ, Dos Santos RAS, Sharma NM, Patel KP, Frézard F.

Nanomedicine. 2018 Apr;14(3):781-788. doi: 10.1016/j.nano.2017.12.007. Epub 2017 Dec 24. Review.

11.

Angiotensin-(1-7) Promotes Resolution of Neutrophilic Inflammation in a Model of Antigen-Induced Arthritis in Mice.

Barroso LC, Magalhaes GS, Galvão I, Reis AC, Souza DG, Sousa LP, Santos RAS, Campagnole-Santos MJ, Pinho V, Teixeira MM.

Front Immunol. 2017 Nov 20;8:1596. doi: 10.3389/fimmu.2017.01596. eCollection 2017.

12.

Hypotensive effect induced by microinjection of Alamandine, a derivative of angiotensin-(1-7), into caudal ventrolateral medulla of 2K1C hypertensive rats.

Soares ER, Barbosa CM, Campagnole-Santos MJ, Santos RAS, Alzamora AC.

Peptides. 2017 Oct;96:67-75. doi: 10.1016/j.peptides.2017.09.005. Epub 2017 Sep 8.

PMID:
28889964
13.

The Renin-Angiotensin System and the Neurodegenerative Diseases: A Brief Review.

Almeida-Santos AF, Kangussu LM, Campagnole-Santos MJ.

Protein Pept Lett. 2017 Nov 17;24(9):841-853. doi: 10.2174/0929866524666170822120258. Review.

PMID:
28828974
14.

Reduced anxiety-like behavior in transgenic rats with chronically overproduction of angiotensin-(1-7): Role of the Mas receptor.

Kangussu LM, Almeida-Santos AF, Moreira FA, Fontes MAP, Santos RAS, Aguiar DC, Campagnole-Santos MJ.

Behav Brain Res. 2017 Jul 28;331:193-198. doi: 10.1016/j.bbr.2017.05.026. Epub 2017 May 11.

PMID:
28502733
15.

Swimming training induces liver adaptations to oxidative stress and insulin sensitivity in rats submitted to high-fat diet.

Zacarias AC, Barbosa MA, Guerra-Sá R, De Castro UGM, Bezerra FS, de Lima WG, Cardoso LM, Santos RASD, Campagnole-Santos MJ, Alzamora AC.

Redox Rep. 2017 Nov;22(6):515-523. doi: 10.1080/13510002.2017.1315513. Epub 2017 Apr 13.

PMID:
28403686
16.

Chronic overexpression of angiotensin-(1-7) in rats reduces cardiac reactivity to acute stress and dampens anxious behavior.

Moura Santos D, Ribeiro Marins F, Limborço-Filho M, de Oliveira ML, Hamamoto D, Xavier CH, Moreira FA, Santos RA, Campagnole-Santos MJ, Peliky Fontes MA.

Stress. 2017 Mar;20(2):189-196. doi: 10.1080/10253890.2017.1296949. Epub 2017 Mar 13.

PMID:
28288545
17.

Chronic allergic pulmonary inflammation is aggravated in angiotensin-(1-7) Mas receptor knockout mice.

Magalhães GS, Rodrigues-Machado MG, Motta-Santos D, Alenina N, Bader M, Santos RA, Barcelos LS, Campagnole-Santos MJ.

Am J Physiol Lung Cell Mol Physiol. 2016 Dec 1;311(6):L1141-L1148. doi: 10.1152/ajplung.00029.2016. Epub 2016 Nov 4.

18.

Anxiolytic- and antidepressant-like effects of angiotensin-(1-7) in hypertensive transgenic (mRen2)27 rats.

Almeida-Santos AF, Kangussu LM, Moreira FA, Santos RA, Aguiar DC, Campagnole-Santos MJ.

Clin Sci (Lond). 2016 Jul 1;130(14):1247-55. doi: 10.1042/CS20160116. Epub 2016 Apr 20.

PMID:
27129185
19.

Effects of ACE2 deficiency on physical performance and physiological adaptations of cardiac and skeletal muscle to exercise.

Motta-Santos D, Dos Santos RA, Oliveira M, Qadri F, Poglitsch M, Mosienko V, Kappes Becker L, Campagnole-Santos MJ, M Penninger J, Alenina N, Bader M.

Hypertens Res. 2016 Jul;39(7):506-12. doi: 10.1038/hr.2016.28. Epub 2016 Apr 7.

PMID:
27053009
20.

Differential control of vasomotion by angiotensins in the rostral ventrolateral medulla of hypertensive rats.

Ferreira PM, Xavier CH, Alzamora AC, Santos RA, Campagnole-Santos MJ.

Neuropeptides. 2015 Oct;53:11-8. doi: 10.1016/j.npep.2015.09.002. Epub 2015 Sep 9.

PMID:
26390943
21.

Time-course effects of aerobic exercise training on cardiovascular and renal parameters in 2K1C renovascular hypertensive rats.

Maia RC, Sousa LE, Santos RA, Silva ME, Lima WG, Campagnole-Santos MJ, Alzamora AC.

Braz J Med Biol Res. 2015 Nov;48(11):1010-22. doi: 10.1590/1414-431X20154499. Epub 2015 Aug 11.

22.

Exercise training restores oxidative stress and nitric oxide synthases in the rostral ventrolateral medulla of renovascular hypertensive rats.

Sousa LE, Magalhães WG, Bezerra FS, Santos RA, Campagnole-Santos MJ, Isoldi MC, Alzamora AC.

Free Radic Res. 2015;49(11):1335-43. doi: 10.3109/10715762.2015.1069291. Epub 2015 Aug 11.

PMID:
26140386
23.

Beneficial effects of angiotensin-(1-7) against deoxycorticosterone acetate-induced diastolic dysfunction occur independently of changes in blood pressure.

de Almeida PW, Melo MB, Lima Rde F, Gavioli M, Santiago NM, Greco L, Jesus IC, Nocchi E, Parreira A, Alves MN, Mitraud L, Resende RR, Campagnole-Santos MJ, Dos Santos RA, Guatimosim S.

Hypertension. 2015 Aug;66(2):389-95. doi: 10.1161/HYPERTENSIONAHA.114.04893. Epub 2015 Jun 15.

PMID:
26077567
24.

Activation of angiotensin-(1-7)/Mas axis in the brain lowers blood pressure and attenuates cardiac remodeling in hypertensive transgenic (mRen2)27 rats.

Kangussu LM, Guimaraes PS, Nadu AP, Melo MB, Santos RA, Campagnole-Santos MJ.

Neuropharmacology. 2015 Oct;97:58-66. doi: 10.1016/j.neuropharm.2015.04.036. Epub 2015 May 15.

PMID:
25983274
25.

Angiotensin-(1-7) attenuates airway remodelling and hyperresponsiveness in a model of chronic allergic lung inflammation.

Magalhães GS, Rodrigues-Machado MG, Motta-Santos D, Silva AR, Caliari MV, Prata LO, Abreu SC, Rocco PR, Barcelos LS, Santos RA, Campagnole-Santos MJ.

Br J Pharmacol. 2015 May;172(9):2330-42. doi: 10.1111/bph.13057. Epub 2015 Mar 18.

26.

Angiotensin-(1-7) in the basolateral amygdala attenuates the cardiovascular response evoked by acute emotional stress.

Oscar CG, Müller-Ribeiro FC, de Castro LG, Martins Lima A, Campagnole-Santos MJ, Santos RA, Xavier CH, Fontes MA.

Brain Res. 2015 Jan 12;1594:183-9. doi: 10.1016/j.brainres.2014.11.006. Epub 2014 Nov 13.

PMID:
25446442
27.

Swimming training promotes cardiac remodeling and alters the expression of mRNA and protein levels involved in calcium handling in hypertensive rats.

Locatelli J, Monteiro de Assis LV, Morais Araújo C, Carvalho Alzamora A, Wanderson Geraldo de Lima, Campagnole-Santos MJ, Augusto dos Santos R, Isoldi MC.

Life Sci. 2014 Nov 11;117(2):67-74.

PMID:
25283082
28.

Cross talk between angiotensin-(1-7)/Mas axis and sirtuins in adipose tissue and metabolism of high-fat feed mice.

Oliveira Andrade JM, Paraíso AF, Garcia ZM, Ferreira AV, Sinisterra RD, Sousa FB, Guimarães AL, de Paula AM, Campagnole-Santos MJ, dos Santos RA, Santos SH.

Peptides. 2014 May;55:158-65. doi: 10.1016/j.peptides.2014.03.006. Epub 2014 Mar 15.

PMID:
24642355
29.

Development of attenuated baroreflexes in obese Zucker rats coincides with impaired activation of nucleus tractus solitarius.

Guimaraes PS, Huber DA, Campagnole-Santos MJ, Schreihofer AM.

Am J Physiol Regul Integr Comp Physiol. 2014 May;306(9):R681-92. doi: 10.1152/ajpregu.00537.2013. Epub 2014 Feb 26.

30.

Increasing angiotensin-(1-7) levels in the brain attenuates metabolic syndrome-related risks in fructose-fed rats.

Guimaraes PS, Oliveira MF, Braga JF, Nadu AP, Schreihofer A, Santos RA, Campagnole-Santos MJ.

Hypertension. 2014 May;63(5):1078-85. doi: 10.1161/HYPERTENSIONAHA.113.01847. Epub 2014 Feb 10.

PMID:
24516106
31.

Age-dependent effect of high-fructose and high-fat diets on lipid metabolism and lipid accumulation in liver and kidney of rats.

de Castro UG, dos Santos RA, Silva ME, de Lima WG, Campagnole-Santos MJ, Alzamora AC.

Lipids Health Dis. 2013 Sep 18;12:136. doi: 10.1186/1476-511X-12-136.

32.

Angiotensin-(1-7) attenuates the anxiety and depression-like behaviors in transgenic rats with low brain angiotensinogen.

Kangussu LM, Almeida-Santos AF, Bader M, Alenina N, Fontes MA, Santos RA, Aguiar DC, Campagnole-Santos MJ.

Behav Brain Res. 2013 Nov 15;257:25-30. doi: 10.1016/j.bbr.2013.09.003. Epub 2013 Sep 7.

PMID:
24016839
33.

AVE 0991, a non-peptide mimic of angiotensin-(1-7) effects, attenuates pulmonary remodelling in a model of chronic asthma.

Rodrigues-Machado MG, Magalhães GS, Cardoso JA, Kangussu LM, Murari A, Caliari MV, Oliveira ML, Cara DC, Noviello ML, Marques FD, Pereira JM, Lautner RQ, Santos RA, Campagnole-Santos MJ.

Br J Pharmacol. 2013 Oct;170(4):835-46. doi: 10.1111/bph.12318.

34.

Oral formulation of angiotensin-(1-7) improves lipid metabolism and prevents high-fat diet-induced hepatic steatosis and inflammation in mice.

Feltenberger JD, Andrade JM, Paraíso A, Barros LO, Filho AB, Sinisterra RD, Sousa FB, Guimarães AL, de Paula AM, Campagnole-Santos MJ, Qureshi M, dos Santos RA, Santos SH.

Hypertension. 2013 Aug;62(2):324-30. doi: 10.1161/HYPERTENSIONAHA.111.00919. Epub 2013 Jun 10.

PMID:
23753417
35.
36.

Association of an oral formulation of angiotensin-(1-7) with atenolol improves lipid metabolism in hypertensive rats.

Santos CF, Santos SH, Ferreira AV, Botion LM, Santos RA, Campagnole-Santos MJ.

Peptides. 2013 May;43:155-9. doi: 10.1016/j.peptides.2013.03.009. Epub 2013 Mar 18.

37.

Discovery and characterization of alamandine: a novel component of the renin-angiotensin system.

Lautner RQ, Villela DC, Fraga-Silva RA, Silva N, Verano-Braga T, Costa-Fraga F, Jankowski J, Jankowski V, Sousa F, Alzamora A, Soares E, Barbosa C, Kjeldsen F, Oliveira A, Braga J, Savergnini S, Maia G, Peluso AB, Passos-Silva D, Ferreira A, Alves F, Martins A, Raizada M, Paula R, Motta-Santos D, Klempin F, Pimenta A, Alenina N, Sinisterra R, Bader M, Campagnole-Santos MJ, Santos RA.

Circ Res. 2013 Apr 12;112(8):1104-11. doi: 10.1161/CIRCRESAHA.113.301077. Epub 2013 Feb 27. Erratum in: Circ Res. 2013 May 24;112(11):e156. Kemplin, Friederike [corrected to Klempin, Friederike].

PMID:
23446738
38.

Diet composition modulates expression of sirtuins and renin-angiotensin system components in adipose tissue.

de Pinho L, Andrade JM, Paraíso A, Filho AB, Feltenberger JD, Guimarães AL, de Paula AM, Caldeira AP, de Carvalho Botelho AC, Campagnole-Santos MJ, Sousa Santos SH.

Obesity (Silver Spring). 2013 Sep;21(9):1830-5. doi: 10.1002/oby.20305. Epub 2013 May 24.

39.

The nonpeptide ANG-(1-7) mimic AVE 0991 attenuates cardiac remodeling and improves baroreflex sensitivity in renovascular hypertensive rats.

Cunha TM, Lima WG, Silva ME, Souza Santos RA, Campagnole-Santos MJ, Alzamora AC.

Life Sci. 2013 Mar 12;92(4-5):266-75. doi: 10.1016/j.lfs.2012.12.008. Epub 2013 Jan 16.

PMID:
23333828
40.

Exercise induces renin-angiotensin system unbalance and high collagen expression in the heart of Mas-deficient mice.

Guimarães GG, Santos SH, Oliveira ML, Pimenta-Velloso EP, Motta DF, Martins AS, Alenina N, Bader M, Santos RA, Campagnole-Santos MJ.

Peptides. 2012 Nov;38(1):54-61. doi: 10.1016/j.peptides.2012.05.024. Epub 2012 Aug 18.

41.

Decreased hepatic gluconeogenesis in transgenic rats with increased circulating angiotensin-(1-7).

Bilman V, Mares-Guia L, Nadu AP, Bader M, Campagnole-Santos MJ, Santos RA, Santos SH.

Peptides. 2012 Oct;37(2):247-51. doi: 10.1016/j.peptides.2012.08.002. Epub 2012 Aug 10.

42.

Increased circulating angiotensin-(1-7) protects white adipose tissue against development of a proinflammatory state stimulated by a high-fat diet.

Santos SH, Fernandes LR, Pereira CS, Guimarães AL, de Paula AM, Campagnole-Santos MJ, Alvarez-Leite JI, Bader M, Santos RA.

Regul Pept. 2012 Oct 10;178(1-3):64-70. doi: 10.1016/j.regpep.2012.06.009. Epub 2012 Jun 29.

43.

Chronic infusion of angiotensin-(1-7) into the lateral ventricle of the brain attenuates hypertension in DOCA-salt rats.

Guimaraes PS, Santiago NM, Xavier CH, Velloso EP, Fontes MA, Santos RA, Campagnole-Santos MJ.

Am J Physiol Heart Circ Physiol. 2012 Aug 1;303(3):H393-400. doi: 10.1152/ajpheart.00075.2012. Epub 2012 Jun 1.

44.

The cardiac expression of Mas receptor is responsive to different physiological and pathological stimuli.

Dias-Peixoto MF, Ferreira AJ, Almeida PW, Braga VB, Coutinho DC, Melo DS, Gomes Filho A, Melo MB, Greco L, Campagnole-Santos MJ, Lima RF, Santos RA, Guatimosim S.

Peptides. 2012 Jun;35(2):196-201. doi: 10.1016/j.peptides.2012.03.022. Epub 2012 Apr 6.

45.

Cardiovascular responses evoked by activation or blockade of GABA(A) receptors in the hypothalamic PVN are attenuated in transgenic rats with low brain angiotensinogen.

Gomes da Silva AQ, Xavier CH, Campagnole-Santos MJ, Caligiorne SM, Baltatu OC, Bader M, Santos RA, Fontes MA.

Brain Res. 2012 Apr 11;1448:101-10. doi: 10.1016/j.brainres.2012.02.021. Epub 2012 Feb 16.

46.

NADPH phagocyte oxidase knockout mice control Trypanosoma cruzi proliferation, but develop circulatory collapse and succumb to infection.

Santiago HC, Gonzalez Lombana CZ, Macedo JP, Utsch L, Tafuri WL, Campagnole-Santos MJ, Alves RO, Alves-Filho JC, Romanha AJ, Cunha FQ, Teixeira MM, Radi R, Vieira LQ.

PLoS Negl Trop Dis. 2012;6(2):e1492. doi: 10.1371/journal.pntd.0001492. Epub 2012 Feb 14.

47.

Nitric oxide at the CVLM is involved in the attenuation of the reflex bradycardia in renovascular hypertensive rats.

de Castro UG, de Sousa GG, Machado Rdo P, Isoldi MC, Silva ME, Nadu AP, Sousa LE, Santos RA, Campagnole-Santos MJ, Alzamora AC.

Nitric Oxide. 2012 Feb 15;26(2):118-25. doi: 10.1016/j.niox.2012.01.002. Epub 2012 Jan 14.

48.

Cardiac and renal effects induced by different exercise workloads in renovascular hypertensive rats.

Soares ER, Lima WG, Machado RP, Carneiro CM, Silva ME, Rodrigues MC, De Castro UG, Santos RA, Campagnole-Santos MJ, Alzamora AC.

Braz J Med Biol Res. 2011 Jun;44(6):573-82. Epub 2011 Apr 20.

49.

Altered cardiovascular reflexes responses in conscious Angiotensin-(1-7) receptor Mas-knockout mice.

de Moura MM, dos Santos RA, Campagnole-Santos MJ, Todiras M, Bader M, Alenina N, Haibara AS.

Peptides. 2010 Oct;31(10):1934-9. doi: 10.1016/j.peptides.2010.06.030. Epub 2010 Jul 21.

PMID:
20603170
50.

Lifetime overproduction of circulating Angiotensin-(1-7) attenuates deoxycorticosterone acetate-salt hypertension-induced cardiac dysfunction and remodeling.

Santiago NM, Guimarães PS, Sirvente RA, Oliveira LA, Irigoyen MC, Santos RA, Campagnole-Santos MJ.

Hypertension. 2010 Apr;55(4):889-96. doi: 10.1161/HYPERTENSIONAHA.110.149815. Epub 2010 Mar 8.

PMID:
20212262

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