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Items: 1 to 50 of 156

1.

An antibiofilm coating of 5-aryl-2-aminoimidazole covalently attached to a titanium surface.

Peeters E, Hooyberghs G, Robijns S, De Weerdt A, Kucharíková S, Tournu H, Braem A, Čeh K, Majdič G, Španič T, Pogorevc E, Claes B, Dovgan B, Girandon L, Impellizzeri F, Erdtmann M, Krona A, Vleugels J, Fröhlich M, Garcia-Forgas J, De Brucker K, Cammue BPA, Thevissen K, Van Dijck P, Vanderleyden J, Van der Eycken E, Steenackers HP.

J Biomed Mater Res B Appl Biomater. 2018 Dec 13. doi: 10.1002/jbm.b.34283. [Epub ahead of print]

PMID:
30549192
2.

Structure-activity relationship study of the antimicrobial CRAMP-derived peptide CRAMP20-33.

Winderickx S, De Brucker K, Bird MJ, Windmolders P, Meert E, Cammue BPA, Thevissen K.

Peptides. 2018 Nov;109:33-38. doi: 10.1016/j.peptides.2018.08.013. Epub 2018 Aug 31.

PMID:
30176261
3.

Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms.

Van Dijck P, Sjollema J, Cammue BP, Lagrou K, Berman J, d'Enfert C, Andes DR, Arendrup MC, Brakhage AA, Calderone R, Cantón E, Coenye T, Cos P, Cowen LE, Edgerton M, Espinel-Ingroff A, Filler SG, Ghannoum M, Gow NAR, Haas H, Jabra-Rizk MA, Johnson EM, Lockhart SR, Lopez-Ribot JL, Maertens J, Munro CA, Nett JE, Nobile CJ, Pfaller MA, Ramage G, Sanglard D, Sanguinetti M, Spriet I, Verweij PE, Warris A, Wauters J, Yeaman MR, Zaat SAJ, Thevissen K.

Microb Cell. 2018 Jun 14;5(7):300-326. doi: 10.15698/mic2018.07.638. Review.

4.

Hub Protein Controversy: Taking a Closer Look at Plant Stress Response Hubs.

Vandereyken K, Van Leene J, De Coninck B, Cammue BPA.

Front Plant Sci. 2018 Jun 5;9:694. doi: 10.3389/fpls.2018.00694. eCollection 2018. Review.

5.

Repurposing AM404 for the treatment of oral infections by Porphyromonas gingivalis.

Gerits E, Spincemaille P, De Cremer K, De Brucker K, Beullens S, Thevissen K, Cammue BPA, Vandamme K, Fauvart M, Verstraeten N, Michiels J.

Clin Exp Dent Res. 2017 Apr 7;3(2):69-76. doi: 10.1002/cre2.65. eCollection 2017 Apr.

6.

The Antifungal Plant Defensin HsAFP1 Is a Phosphatidic Acid-Interacting Peptide Inducing Membrane Permeabilization.

Cools TL, Vriens K, Struyfs C, Verbandt S, Ramada MHS, Brand GD, Bloch C Jr, Koch B, Traven A, Drijfhout JW, Demuyser L, Kucharíková S, Van Dijck P, Spasic D, Lammertyn J, Cammue BPA, Thevissen K.

Front Microbiol. 2017 Nov 21;8:2295. doi: 10.3389/fmicb.2017.02295. eCollection 2017.

7.

Increasing the Fungicidal Action of Amphotericin B by Inhibiting the Nitric Oxide-Dependent Tolerance Pathway.

Vriens K, Kumar PT, Struyfs C, Cools TL, Spincemaille P, Kokalj T, Sampaio-Marques B, Ludovico P, Lammertyn J, Cammue BPA, Thevissen K.

Oxid Med Cell Longev. 2017;2017:4064628. doi: 10.1155/2017/4064628. Epub 2017 Oct 10.

8.

A Linear 19-Mer Plant Defensin-Derived Peptide Acts Synergistically with Caspofungin against Candida albicans Biofilms.

Cools TL, Struyfs C, Drijfhout JW, Kucharíková S, Lobo Romero C, Van Dijck P, Ramada MHS, Bloch C Jr, Cammue BPA, Thevissen K.

Front Microbiol. 2017 Oct 20;8:2051. doi: 10.3389/fmicb.2017.02051. eCollection 2017.

9.

Fungal Glucosylceramide-Specific Camelid Single Domain Antibodies Are Characterized by Broad Spectrum Antifungal Activity.

De Coninck B, Verheesen P, Vos CM, Van Daele I, De Bolle MF, Vieira JV, Peferoen M, Cammue BPA, Thevissen K.

Front Microbiol. 2017 Jun 14;8:1059. doi: 10.3389/fmicb.2017.01059. eCollection 2017.

10.

Antifungal plant defensins: increased insight in their mode of action as a basis for their use to combat fungal infections.

Cools TL, Struyfs C, Cammue BP, Thevissen K.

Future Microbiol. 2017 Apr;12:441-454. doi: 10.2217/fmb-2016-0181. Epub 2017 Mar 24.

PMID:
28339295
11.

Alternating Current Electrophoretic Deposition for the Immobilization of Antimicrobial Agents on Titanium Implant Surfaces.

Braem A, De Brucker K, Delattin N, Killian MS, Roeffaers MB, Yoshioka T, Hayakawa S, Schmuki P, Cammue BP, Virtanen S, Thevissen K, Neirinck B.

ACS Appl Mater Interfaces. 2017 Mar 15;9(10):8533-8546. doi: 10.1021/acsami.6b16433. Epub 2017 Mar 6.

PMID:
28211996
12.

ARA-PEPs: a repository of putative sORF-encoded peptides in Arabidopsis thaliana.

Hazarika RR, De Coninck B, Yamamoto LR, Martin LR, Cammue BP, van Noort V.

BMC Bioinformatics. 2017 Jan 17;18(1):37. doi: 10.1186/s12859-016-1458-y.

13.

In vitro activity of the antiasthmatic drug zafirlukast against the oral pathogens Porphyromonas gingivalis and Streptococcus mutans.

Gerits E, Van der Massen I, Vandamme K, De Cremer K, De Brucker K, Thevissen K, Cammue BPA, Beullens S, Fauvart M, Verstraeten N, Michiels J, Roberts M.

FEMS Microbiol Lett. 2017 Jan 1;364(2). doi: 10.1093/femsle/fnx005.

PMID:
28087617
14.

Controlled release of chlorhexidine from a mesoporous silica-containing macroporous titanium dental implant prevents microbial biofilm formation.

De Cremer K, Braem A, Gerits E, De Brucker K, Vandamme K, Martens JA, Michiels J, Vleugels J, Cammue BP, Thevissen K.

Eur Cell Mater. 2017 Jan 11;33:13-27. doi: 10.22203/eCM.v033a02.

15.

Repurposing Toremifene for Treatment of Oral Bacterial Infections.

Gerits E, Defraine V, Vandamme K, De Cremer K, De Brucker K, Thevissen K, Cammue BP, Beullens S, Fauvart M, Verstraeten N, Michiels J.

Antimicrob Agents Chemother. 2017 Feb 23;61(3). pii: e01846-16. doi: 10.1128/AAC.01846-16. Print 2017 Mar.

16.

Expanding the pharmacological profile of κ-hefutoxin 1 and analogues: A focus on the inhibitory effect on the oncogenic channel Kv10.1.

Moreels L, Peigneur S, Yamaguchi Y, Vriens K, Waelkens E, Zhu S, Thevissen K, Cammue BPA, Sato K, Tytgat J.

Peptides. 2017 Dec;98:43-50. doi: 10.1016/j.peptides.2016.08.008. Epub 2016 Aug 28.

PMID:
27578329
17.

The antifungal plant defensin AtPDF2.3 from Arabidopsis thaliana blocks potassium channels.

Vriens K, Peigneur S, De Coninck B, Tytgat J, Cammue BP, Thevissen K.

Sci Rep. 2016 Aug 30;6:32121. doi: 10.1038/srep32121.

18.

Modulation of the Substitution Pattern of 5-Aryl-2-Aminoimidazoles Allows Fine-Tuning of Their Antibiofilm Activity Spectrum and Toxicity.

Peeters E, Hooyberghs G, Robijns S, Waldrant K, De Weerdt A, Delattin N, Liebens V, Kucharíková S, Tournu H, Verstraeten N, Dovgan B, Girandon L, Fröhlich M, De Brucker K, Van Dijck P, Michiels J, Cammue BP, Thevissen K, Vanderleyden J, Van der Eycken E, Steenackers HP.

Antimicrob Agents Chemother. 2016 Oct 21;60(11):6483-6497. doi: 10.1128/AAC.00035-16. Print 2016 Nov.

19.

Glutaredoxin GRXS17 Associates with the Cytosolic Iron-Sulfur Cluster Assembly Pathway.

Iñigo S, Durand AN, Ritter A, Le Gall S, Termathe M, Klassen R, Tohge T, De Coninck B, Van Leene J, De Clercq R, Cammue BP, Fernie AR, Gevaert K, De Jaeger G, Leidel SA, Schaffrath R, Van Lijsebettens M, Pauwels L, Goossens A.

Plant Physiol. 2016 Oct;172(2):858-873. Epub 2016 Aug 8.

20.

Identification of survival-promoting OSIP108 peptide variants and their internalization in human cells.

Verbandt S, Henriques ST, Spincemaille P, Harvey PJ, Chandhok G, Sauer V, De Coninck B, Cassiman D, Craik DJ, Cammue BPA, De Cremer K, Thevissen K.

Mech Ageing Dev. 2017 Jan;161(Pt B):247-254. doi: 10.1016/j.mad.2016.07.013. Epub 2016 Aug 1.

PMID:
27491841
21.

Antimicrobial Peptides as a Strategy to Combat Fungal Biofilms.

Delattin N, Brucker K, Cremer K, Cammue BP, Thevissen K.

Curr Top Med Chem. 2017;17(5):604-612. Review.

PMID:
27411323
22.

Yeast as a model for the identification of novel survival-promoting compounds applicable to treat degenerative diseases.

Verbandt S, Cammue BPA, Thevissen K.

Mech Ageing Dev. 2017 Jan;161(Pt B):306-316. doi: 10.1016/j.mad.2016.06.003. Epub 2016 Jun 7. Review.

PMID:
27287065
23.

Stimulation of superoxide production increases fungicidal action of miconazole against Candida albicans biofilms.

De Cremer K, De Brucker K, Staes I, Peeters A, Van den Driessche F, Coenye T, Cammue BP, Thevissen K.

Sci Rep. 2016 Jun 7;6:27463. doi: 10.1038/srep27463.

24.

Non-disulfide-bridged peptides from Tityus serrulatus venom: Evidence for proline-free ACE-inhibitors.

Pucca MB, Cerni FA, Pinheiro-Junior EL, Zoccal KF, Bordon KCF, Amorim FG, Peigneur S, Vriens K, Thevissen K, Cammue BPA, Júnior RBM, Arruda E, Faccioli LH, Tytgat J, Arantes EC.

Peptides. 2016 Aug;82:44-51. doi: 10.1016/j.peptides.2016.05.008. Epub 2016 May 21.

PMID:
27221550
25.

Elucidation of the Mode of Action of a New Antibacterial Compound Active against Staphylococcus aureus and Pseudomonas aeruginosa.

Gerits E, Blommaert E, Lippell A, O'Neill AJ, Weytjens B, De Maeyer D, Fierro AC, Marchal K, Marchand A, Chaltin P, Spincemaille P, De Brucker K, Thevissen K, Cammue BP, Swings T, Liebens V, Fauvart M, Verstraeten N, Michiels J.

PLoS One. 2016 May 11;11(5):e0155139. doi: 10.1371/journal.pone.0155139. eCollection 2016.

26.

Antibacterial activity of a new broad-spectrum antibiotic covalently bound to titanium surfaces.

Gerits E, Kucharíková S, Van Dijck P, Erdtmann M, Krona A, Lövenklev M, Fröhlich M, Dovgan B, Impellizzeri F, Braem A, Vleugels J, Robijns SC, Steenackers HP, Vanderleyden J, De Brucker K, Thevissen K, Cammue BP, Fauvart M, Verstraeten N, Michiels J.

J Orthop Res. 2016 Dec;34(12):2191-2198. doi: 10.1002/jor.23238. Epub 2016 Apr 6.

27.

Covalent immobilization of antimicrobial agents on titanium prevents Staphylococcus aureus and Candida albicans colonization and biofilm formation.

Kucharíková S, Gerits E, De Brucker K, Braem A, Ceh K, Majdič G, Španič T, Pogorevc E, Verstraeten N, Tournu H, Delattin N, Impellizzeri F, Erdtmann M, Krona A, Lövenklev M, Knezevic M, Fröhlich M, Vleugels J, Fauvart M, de Silva WJ, Vandamme K, Garcia-Forgas J, Cammue BP, Michiels J, Van Dijck P, Thevissen K.

J Antimicrob Chemother. 2016 Apr;71(4):936-45. doi: 10.1093/jac/dkv437. Epub 2015 Dec 24.

PMID:
26702917
28.

The radish defensins RsAFP1 and RsAFP2 act synergistically with caspofungin against Candida albicans biofilms.

Vriens K, Cools TL, Harvey PJ, Craik DJ, Braem A, Vleugels J, De Coninck B, Cammue BP, Thevissen K.

Peptides. 2016 Jan;75:71-9. doi: 10.1016/j.peptides.2015.11.001. Epub 2015 Nov 28.

PMID:
26592804
29.

Protocol for Determination of the Persister Subpopulation in Candida Albicans Biofilms.

De Brucker K, De Cremer K, Cammue BP, Thevissen K.

Methods Mol Biol. 2016;1333:67-72. doi: 10.1007/978-1-4939-2854-5_6.

PMID:
26468100
30.

The Plant Peptidome: An Expanding Repertoire of Structural Features and Biological Functions.

Tavormina P, De Coninck B, Nikonorova N, De Smet I, Cammue BP.

Plant Cell. 2015 Aug;27(8):2095-118. doi: 10.1105/tpc.15.00440. Epub 2015 Aug 14. Review.

31.

Synergistic Activity of the Plant Defensin HsAFP1 and Caspofungin against Candida albicans Biofilms and Planktonic Cultures.

Vriens K, Cools TL, Harvey PJ, Craik DJ, Spincemaille P, Cassiman D, Braem A, Vleugels J, Nibbering PH, Drijfhout JW, De Coninck B, Cammue BP, Thevissen K.

PLoS One. 2015 Aug 6;10(8):e0132701. doi: 10.1371/journal.pone.0132701. eCollection 2015.

32.

Combinatorial drug approaches to tackle Candida albicans biofilms.

De Cremer K, Staes I, Delattin N, Cammue BP, Thevissen K, De Brucker K.

Expert Rev Anti Infect Ther. 2015 Aug;13(8):973-84. doi: 10.1586/14787210.2015.1056162. Epub 2015 Jun 12. Review.

PMID:
26070384
33.

Fungal β-1,3-glucan increases ofloxacin tolerance of Escherichia coli in a polymicrobial E. coli/Candida albicans biofilm.

De Brucker K, Tan Y, Vints K, De Cremer K, Braem A, Verstraeten N, Michiels J, Vleugels J, Cammue BP, Thevissen K.

Antimicrob Agents Chemother. 2015;59(6):3052-8. doi: 10.1128/AAC.04650-14. Epub 2015 Mar 9.

34.

Digital microfluidics for time-resolved cytotoxicity studies on single non-adherent yeast cells.

Kumar PT, Vriens K, Cornaglia M, Gijs M, Kokalj T, Thevissen K, Geeraerd A, Cammue BP, Puers R, Lammertyn J.

Lab Chip. 2015 Apr 21;15(8):1852-60. doi: 10.1039/c4lc01469c.

PMID:
25710603
35.

Novel anti-infective implant substrates: controlled release of antibiofilm compounds from mesoporous silica-containing macroporous titanium.

Braem A, De Cremer K, Delattin N, De Brucker K, Neirinck B, Vandamme K, Martens JA, Michiels J, Vleugels J, Cammue BP, Thevissen K.

Colloids Surf B Biointerfaces. 2015 Feb 1;126:481-8. doi: 10.1016/j.colsurfb.2014.12.054. Epub 2015 Jan 7.

PMID:
25601097
36.

ARACINs, Brassicaceae-specific peptides exhibiting antifungal activities against necrotrophic pathogens in Arabidopsis.

Neukermans J, Inzé A, Mathys J, De Coninck B, van de Cotte B, Cammue BP, Van Breusegem F.

Plant Physiol. 2015 Mar;167(3):1017-29. doi: 10.1104/pp.114.255505. Epub 2015 Jan 15.

37.

2-(2-oxo-morpholin-3-yl)-acetamide derivatives as broad-spectrum antifungal agents.

Bardiot D, Thevissen K, De Brucker K, Peeters A, Cos P, Taborda CP, McNaughton M, Maes L, Chaltin P, Cammue BP, Marchand A.

J Med Chem. 2015 Feb 12;58(3):1502-12. doi: 10.1021/jm501814x. Epub 2015 Jan 28.

PMID:
25585716
38.

Ultraviolet-B radiation stimulates downward leaf curling in Arabidopsis thaliana.

Fierro AC, Leroux O, De Coninck B, Cammue BP, Marchal K, Prinsen E, Van Der Straeten D, Vandenbussche F.

Plant Physiol Biochem. 2015 Aug;93:9-17. doi: 10.1016/j.plaphy.2014.12.012. Epub 2014 Dec 17.

PMID:
25542780
39.

Identification and characterization of an anti-pseudomonal dichlorocarbazol derivative displaying anti-biofilm activity.

Liebens V, Gerits E, Knapen WJ, Swings T, Beullens S, Steenackers HP, Robijns S, Lippell A, O'Neill AJ, Veber M, Fröhlich M, Krona A, Lövenklev M, Corbau R, Marchand A, Chaltin P, De Brucker K, Thevissen K, Cammue BP, Fauvart M, Verstraeten N, Michiels J.

Bioorg Med Chem Lett. 2014 Dec 1;24(23):5404-8.

PMID:
25453797
40.

Artemisinins, new miconazole potentiators resulting in increased activity against Candida albicans biofilms.

De Cremer K, Lanckacker E, Cools TL, Bax M, De Brucker K, Cos P, Cammue BP, Thevissen K.

Antimicrob Agents Chemother. 2015 Jan;59(1):421-6. doi: 10.1128/AAC.04229-14. Epub 2014 Nov 3.

41.

Angiotensin II type 1 receptor blockers increase tolerance of cells to copper and cisplatin.

Spincemaille P, Chandhok G, Zibert A, Schmidt H, Verbeek J, Chaltin P, Cammue BP, Cassiman D, Thevissen K.

Microb Cell. 2014 Oct 24;1(11):352-364. doi: 10.15698/mic2014.11.175.

42.

Evaluation of the toxicity of 5-aryl-2-aminoimidazole-based biofilm inhibitors against eukaryotic cell lines, bone cells and the nematode Caenorhabditis elegans.

Steenackers H, Dubey A, Robijns S, Ermolat'ev D, Delattin N, Dovgan B, Girandon L, Fröhlich M, De Brucker K, Cammue BP, Thevissen K, Balzarini J, Van der Eycken EV, Vanderleyden J.

Molecules. 2014 Oct 16;19(10):16707-23. doi: 10.3390/molecules191016707.

43.

What lies beneath: belowground defense strategies in plants.

De Coninck B, Timmermans P, Vos C, Cammue BP, Kazan K.

Trends Plant Sci. 2015 Feb;20(2):91-101. doi: 10.1016/j.tplants.2014.09.007. Epub 2014 Oct 9. Review.

PMID:
25307784
44.

Oral administration of the broad-spectrum antibiofilm compound toremifene inhibits Candida albicans and Staphylococcus aureus biofilm formation in vivo.

De Cremer K, Delattin N, De Brucker K, Peeters A, Kucharíková S, Gerits E, Verstraeten N, Michiels J, Van Dijck P, Cammue BP, Thevissen K.

Antimicrob Agents Chemother. 2014 Dec;58(12):7606-10. doi: 10.1128/AAC.03869-14. Epub 2014 Oct 6.

45.

The plant decapeptide OSIP108 can alleviate mitochondrial dysfunction induced by cisplatin in human cells.

Spincemaille P, Alborzinia H, Dekervel J, Windmolders P, van Pelt J, Cassiman D, Cheneval O, Craik DJ, Schur J, Ott I, Wölfl S, Cammue BP, Thevissen K.

Molecules. 2014 Sep 19;19(9):15088-102. doi: 10.3390/molecules190915088.

46.

Assessment of RNAi-induced silencing in banana (Musa spp.).

Dang TV, Windelinckx S, Henry IM, De Coninck B, Cammue BP, Swennen R, Remy S.

BMC Res Notes. 2014 Sep 18;7:655. doi: 10.1186/1756-0500-7-655.

47.

The toolbox of Trichoderma spp. in the biocontrol of Botrytis cinerea disease.

Vos CM, De Cremer K, Cammue BP, De Coninck B.

Mol Plant Pathol. 2015 May;16(4):400-12. doi: 10.1111/mpp.12189. Epub 2014 Oct 22. Review.

PMID:
25171761
48.

Antifungal plant defensins: mechanisms of action and production.

Vriens K, Cammue BP, Thevissen K.

Molecules. 2014 Aug 14;19(8):12280-303. doi: 10.3390/molecules190812280. Review.

49.

The plant decapeptide OSIP108 prevents copper-induced toxicity in various models for Wilson disease.

Spincemaille P, Pham DH, Chandhok G, Verbeek J, Zibert A, Libbrecht L, Schmidt H, Esguerra CV, de Witte PA, Cammue BP, Cassiman D, Thevissen K.

Toxicol Appl Pharmacol. 2014 Oct 15;280(2):345-51. doi: 10.1016/j.taap.2014.08.005. Epub 2014 Aug 16.

PMID:
25134866
50.

Derivatives of the mouse cathelicidin-related antimicrobial peptide (CRAMP) inhibit fungal and bacterial biofilm formation.

De Brucker K, Delattin N, Robijns S, Steenackers H, Verstraeten N, Landuyt B, Luyten W, Schoofs L, Dovgan B, Fröhlich M, Michiels J, Vanderleyden J, Cammue BP, Thevissen K.

Antimicrob Agents Chemother. 2014 Sep;58(9):5395-404. doi: 10.1128/AAC.03045-14. Epub 2014 Jun 30.

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