Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 231


2'-C-Methylated nucleotides terminate virus RNA synthesis by preventing active site closure of the viral RNA-dependent RNA polymerase.

Boehr AK, Arnold JJ, Oh HS, Cameron CE, Boehr DD.

J Biol Chem. 2019 Oct 1. pii: jbc.RA119.010214. doi: 10.1074/jbc.RA119.010214. [Epub ahead of print]


Rational Control of Poliovirus RNA-Dependent RNA Polymerase Fidelity by Modulating Motif-D Loop Conformational Dynamics.

Shi J, Perryman JM, Yang X, Liu X, Musser DM, Boehr AK, Moustafa IM, Arnold JJ, Cameron CE, Boehr DD.

Biochemistry. 2019 Sep 10;58(36):3735-3743. doi: 10.1021/acs.biochem.9b00497. Epub 2019 Aug 26.


Structural characterization of Treponema pallidum Tp0225 reveals an unexpected leucine-rich repeat architecture.

Ramaswamy R, Houston S, Loveless B, Cameron CE, Boulanger MJ.

Acta Crystallogr F Struct Biol Commun. 2019 Jul 1;75(Pt 7):489-495. doi: 10.1107/S2053230X19007726. Epub 2019 Jun 26.


Senecavirus-Specific Recombination Assays Reveal the Intimate Link between Polymerase Fidelity and RNA Recombination.

Li C, Wang H, Shi J, Yang D, Zhou G, Chang J, Cameron CE, Woodman A, Yu L.

J Virol. 2019 Jun 14;93(13). pii: e00576-19. doi: 10.1128/JVI.00576-19. Print 2019 Jul 1.


Antimicrobial peptides from Rana [Lithobates] catesbeiana: Gene structure and bioinformatic identification of novel forms from tadpoles.

Helbing CC, Hammond SA, Jackman SH, Houston S, Warren RL, Cameron CE, Birol I.

Sci Rep. 2019 Feb 6;9(1):1529. doi: 10.1038/s41598-018-38442-1.


Interaction of Treponema pallidum, the syphilis spirochete, with human platelets.

Church B, Wall E, Webb JR, Cameron CE.

PLoS One. 2019 Jan 18;14(1):e0210902. doi: 10.1371/journal.pone.0210902. eCollection 2019.


Predicting Intraserotypic Recombination in Enterovirus 71.

Woodman A, Lee KM, Janissen R, Gong YN, Dekker NH, Shih SR, Cameron CE.

J Virol. 2019 Feb 5;93(4). pii: e02057-18. doi: 10.1128/JVI.02057-18. Print 2019 Feb 15.


Candidate Treponema pallidum biomarkers uncovered in urine from individuals with syphilis using mass spectrometry.

Osbak KK, Van Raemdonck GA, Dom M, Cameron CE, Meehan CJ, Deforce D, Ostade XV, Kenyon CR, Dhaenens M.

Future Microbiol. 2018 Oct;13:1497-1510. doi: 10.2217/fmb-2018-0182. Epub 2018 Oct 12.


Publisher Correction: A naturally occurring antiviral ribonucleotide encoded by the human genome.

Gizzi AS, Grove TL, Arnold JJ, Jose J, Jangra RK, Garforth SJ, Du Q, Cahill SM, Dulyaninova NG, Love JD, Chandran K, Bresnick AR, Cameron CE, Almo SC.

Nature. 2018 Oct;562(7725):E3. doi: 10.1038/s41586-018-0355-0.


A speed-fidelity trade-off determines the mutation rate and virulence of an RNA virus.

Fitzsimmons WJ, Woods RJ, McCrone JT, Woodman A, Arnold JJ, Yennawar M, Evans R, Cameron CE, Lauring AS.

PLoS Biol. 2018 Jun 28;16(6):e2006459. doi: 10.1371/journal.pbio.2006459. eCollection 2018 Jun.


Discovery of Enterovirus A71-like nonstructural genomes in recent circulating viruses of the Enterovirus A species.

Lee KM, Gong YN, Hsieh TH, Woodman A, Dekker NH, Cameron CE, Shih SR.

Emerg Microbes Infect. 2018 Jun 21;7(1):111. doi: 10.1038/s41426-018-0107-0.


A naturally occurring antiviral ribonucleotide encoded by the human genome.

Gizzi AS, Grove TL, Arnold JJ, Jose J, Jangra RK, Garforth SJ, Du Q, Cahill SM, Dulyaninova NG, Love JD, Chandran K, Bresnick AR, Cameron CE, Almo SC.

Nature. 2018 Jun;558(7711):610-614. doi: 10.1038/s41586-018-0238-4. Epub 2018 Jun 20. Erratum in: Nature. 2018 Oct;562(7725):E3.


Hijacking of multiple phospholipid biosynthetic pathways and induction of membrane biogenesis by a picornaviral 3CD protein.

Banerjee S, Aponte-Diaz D, Yeager C, Sharma SD, Ning G, Oh HS, Han Q, Umeda M, Hara Y, Wang RYL, Cameron CE.

PLoS Pathog. 2018 May 21;14(5):e1007086. doi: 10.1371/journal.ppat.1007086. eCollection 2018 May.


Functional insights from proteome-wide structural modeling of Treponema pallidum subspecies pallidum, the causative agent of syphilis.

Houston S, Lithgow KV, Osbak KK, Kenyon CR, Cameron CE.

BMC Struct Biol. 2018 May 16;18(1):7. doi: 10.1186/s12900-018-0086-3.


Multiple poliovirus-induced organelles suggested by comparison of spatiotemporal dynamics of membranous structures and phosphoinositides.

Oh HS, Banerjee S, Aponte-Diaz D, Sharma SD, Aligo J, Lodeiro MF, Ning G, Sharma R, Arnold JJ, Cameron CE.

PLoS Pathog. 2018 Apr 27;14(4):e1007036. doi: 10.1371/journal.ppat.1007036. eCollection 2018 Apr.


Syphilis Vaccine Development: Requirements, Challenges, and Opportunities.

Cameron CE.

Sex Transm Dis. 2018 Sep;45(9S Suppl 1):S17-S19. doi: 10.1097/OLQ.0000000000000831. Review.


Foot-and-mouth disease virus type O specific mutations determine RNA-dependent RNA polymerase fidelity and virus attenuation.

Li C, Wang H, Yuan T, Woodman A, Yang D, Zhou G, Cameron CE, Yu L.

Virology. 2018 May;518:87-94. doi: 10.1016/j.virol.2018.01.030. Epub 2018 Feb 20.


Mitochondrial MDM2 Regulates Respiratory Complex I Activity Independently of p53.

Arena G, Cissé MY, Pyrdziak S, Chatre L, Riscal R, Fuentes M, Arnold JJ, Kastner M, Gayte L, Bertrand-Gaday C, Nay K, Angebault-Prouteau C, Murray K, Chabi B, Koechlin-Ramonatxo C, Orsetti B, Vincent C, Casas F, Marine JC, Etienne-Manneville S, Bernex F, Lombès A, Cameron CE, Dubouchaud H, Ricchetti M, Linares LK, Le Cam L.

Mol Cell. 2018 Feb 15;69(4):594-609.e8. doi: 10.1016/j.molcel.2018.01.023.


The hepatitis C viral nonstructural protein 5A stabilizes growth-regulatory human transcripts.

Guo L, Sharma SD, Debes J, Beisang D, Rattenbacher B, Vlasova-St Louis I, Wiesner DL, Cameron CE, Bohjanen PR.

Nucleic Acids Res. 2018 Mar 16;46(5):2537-2547. doi: 10.1093/nar/gky061.


The RNA-Binding Site of Poliovirus 3C Protein Doubles as a Phosphoinositide-Binding Domain.

Shengjuler D, Chan YM, Sun S, Moustafa IM, Li ZL, Gohara DW, Buck M, Cremer PS, Boehr DD, Cameron CE.

Structure. 2017 Dec 5;25(12):1875-1886.e7. doi: 10.1016/j.str.2017.11.001.


Single-Cell Virology: On-Chip Investigation of Viral Infection Dynamics.

Guo F, Li S, Caglar MU, Mao Z, Liu W, Woodman A, Arnold JJ, Wilke CO, Huang TJ, Cameron CE.

Cell Rep. 2017 Nov 7;21(6):1692-1704. doi: 10.1016/j.celrep.2017.10.051.


Signatures of Nucleotide Analog Incorporation by an RNA-Dependent RNA Polymerase Revealed Using High-Throughput Magnetic Tweezers.

Dulin D, Arnold JJ, van Laar T, Oh HS, Lee C, Perkins AL, Harki DA, Depken M, Cameron CE, Dekker NH.

Cell Rep. 2017 Oct 24;21(4):1063-1076. doi: 10.1016/j.celrep.2017.10.005.


Acoustofluidic bacteria separation.

Li S, Ma F, Bachman H, Cameron CE, Zeng X, Huang TJ.

J Micromech Microeng. 2017 Jan 1;27(1). pii: 015031. doi: 10.1088/1361-6439/27/1/015031. Epub 2016 Nov 30.


PIP-on-a-chip: A Label-free Study of Protein-phosphoinositide Interactions.

Shengjuler D, Sun S, Cremer PS, Cameron CE.

J Vis Exp. 2017 Jul 27;(125). doi: 10.3791/55869.


Accurate nanoscale flexibility measurement of DNA and DNA-protein complexes by atomic force microscopy in liquid.

Murugesapillai D, Bouaziz S, Maher LJ, Israeloff NE, Cameron CE, Williams MC.

Nanoscale. 2017 Aug 10;9(31):11327-11337. doi: 10.1039/c7nr04231k.


Unexpected sequences and structures of mtDNA required for efficient transcription from the first heavy-strand promoter.

Uchida A, Murugesapillai D, Kastner M, Wang Y, Lodeiro MF, Prabhakar S, Oliver GV, Arnold JJ, Maher LJ, Williams MC, Cameron CE.

Elife. 2017 Jul 26;6. pii: e27283. doi: 10.7554/eLife.27283.


UGGT1 enhances enterovirus 71 pathogenicity by promoting viral RNA synthesis and viral replication.

Huang PN, Jheng JR, Arnold JJ, Wang JR, Cameron CE, Shih SR.

PLoS Pathog. 2017 May 17;13(5):e1006375. doi: 10.1371/journal.ppat.1006375. eCollection 2017 May.


Identification of Tp0751 (Pallilysin) as a Treponema pallidum Vascular Adhesin by Heterologous Expression in the Lyme disease Spirochete.

Kao WA, Pětrošová H, Ebady R, Lithgow KV, Rojas P, Zhang Y, Kim YE, Kim YR, Odisho T, Gupta N, Moter A, Cameron CE, Moriarty TJ.

Sci Rep. 2017 May 8;7(1):1538. doi: 10.1038/s41598-017-01589-4.


Respiratory Microbiome of Endangered Southern Resident Killer Whales and Microbiota of Surrounding Sea Surface Microlayer in the Eastern North Pacific.

Raverty SA, Rhodes LD, Zabek E, Eshghi A, Cameron CE, Hanson MB, Schroeder JP.

Sci Rep. 2017 Mar 24;7(1):394. doi: 10.1038/s41598-017-00457-5.


Diet-Induced Obesity Does Not Alter Tigecycline Treatment Efficacy in Murine Lyme Disease.

Pětrošová H, Eshghi A, Anjum Z, Zlotnikov N, Cameron CE, Moriarty TJ.

Front Microbiol. 2017 Feb 24;8:292. doi: 10.3389/fmicb.2017.00292. eCollection 2017.


Mutagen resistance and mutation restriction of St. Louis encephalitis virus.

Griesemer SB, Kramer LD, Van Slyke GA, Pata JD, Gohara DW, Cameron CE, Ciota AT.

J Gen Virol. 2017 Feb;98(2):201-211. doi: 10.1099/jgv.0.000682.


Developmental Relations Among Motor and Cognitive Processes and Mathematics Skills.

Kim H, Duran CAK, Cameron CE, Grissmer D.

Child Dev. 2018 Mar;89(2):476-494. doi: 10.1111/cdev.12752. Epub 2017 Feb 9.


A defined syphilis vaccine candidate inhibits dissemination of Treponema pallidum subspecies pallidum.

Lithgow KV, Hof R, Wetherell C, Phillips D, Houston S, Cameron CE.

Nat Commun. 2017 Feb 1;8:14273. doi: 10.1038/ncomms14273.


Triphosphate Reorientation of the Incoming Nucleotide as a Fidelity Checkpoint in Viral RNA-dependent RNA Polymerases.

Yang X, Liu X, Musser DM, Moustafa IM, Arnold JJ, Cameron CE, Boehr DD.

J Biol Chem. 2017 Mar 3;292(9):3810-3826. doi: 10.1074/jbc.M116.750638. Epub 2017 Jan 18.


A double-edged sword: does highly active antiretroviral therapy contribute to syphilis incidence by impairing immunity to Treponema pallidum?

Rekart ML, Ndifon W, Brunham RC, Dushoff J, Park SW, Rawat S, Cameron CE.

Sex Transm Infect. 2017 Aug;93(5):374-378. doi: 10.1136/sextrans-2016-052870. Epub 2017 Jan 16. Review.


The Structure of Treponema pallidum Tp0624 Reveals a Modular Assembly of Divergently Functionalized and Previously Uncharacterized Domains.

Parker ML, Houston S, Wetherell C, Cameron CE, Boulanger MJ.

PLoS One. 2016 Nov 10;11(11):e0166274. doi: 10.1371/journal.pone.0166274. eCollection 2016.


The Structure of Treponema pallidum Tp0751 (Pallilysin) Reveals a Non-canonical Lipocalin Fold That Mediates Adhesion to Extracellular Matrix Components and Interactions with Host Cells.

Parker ML, Houston S, Pětrošová H, Lithgow KV, Hof R, Wetherell C, Kao WC, Lin YP, Moriarty TJ, Ebady R, Cameron CE, Boulanger MJ.

PLoS Pathog. 2016 Sep 28;12(9):e1005919. doi: 10.1371/journal.ppat.1005919. eCollection 2016 Sep.


Characterizing the Syphilis-Causing Treponema pallidum ssp. pallidum Proteome Using Complementary Mass Spectrometry.

Osbak KK, Houston S, Lithgow KV, Meehan CJ, Strouhal M, Šmajs D, Cameron CE, Van Ostade X, Kenyon CR, Van Raemdonck GA.

PLoS Negl Trop Dis. 2016 Sep 8;10(9):e0004988. doi: 10.1371/journal.pntd.0004988. eCollection 2016 Sep.


Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer.

Oran AR, Adams CM, Zhang XY, Gennaro VJ, Pfeiffer HK, Mellert HS, Seidel HE, Mascioli K, Kaplan J, Gaballa MR, Shen C, Rigoutsos I, King MP, Cotney JL, Arnold JJ, Sharma SD, Martinez-Outschoorn UE, Vakoc CR, Chodosh LA, Thompson JE, Bradner JE, Cameron CE, Shadel GS, Eischen CM, McMahon SB.

Oncotarget. 2016 Nov 8;7(45):72395-72414. doi: 10.18632/oncotarget.11718.


Epidemiological impact of a syphilis vaccine: a simulation study.

Champredon D, Cameron CE, Smieja M, Dushoff J.

Epidemiol Infect. 2016 Nov;144(15):3244-3252. Epub 2016 Aug 1.


Effects of BMS-986094, a Guanosine Nucleotide Analogue, on Mitochondrial DNA Synthesis and Function.

Baumgart BR, Wang F, Kwagh J, Storck C, Euler C, Fuller M, Simic D, Sharma S, Arnold JJ, Cameron CE, Van Vleet TR, Flint O, Bunch RT, Davies MH, Graziano MJ, Sanderson TP.

Toxicol Sci. 2016 Oct;153(2):396-408. doi: 10.1093/toxsci/kfw135. Epub 2016 Jul 27.


Vaccine development for syphilis.

Lithgow KV, Cameron CE.

Expert Rev Vaccines. 2017 Jan;16(1):37-44. Epub 2016 Jul 18. Review.


Biochemical and genetic analysis of the role of the viral polymerase in enterovirus recombination.

Woodman A, Arnold JJ, Cameron CE, Evans DJ.

Nucleic Acids Res. 2016 Aug 19;44(14):6883-95. doi: 10.1093/nar/gkw567. Epub 2016 Jun 17.


Fidelity of Nucleotide Incorporation by the RNA-Dependent RNA Polymerase from Poliovirus.

Cameron CE, Moustafa IM, Arnold JJ.

Enzymes. 2016;39:293-323. doi: 10.1016/bs.enz.2016.02.002. Epub 2016 Mar 28. Review.


Acoustofluidic Transfer of Inflammatory Cells from Human Sputum Samples.

Li S, Ren L, Huang PH, Yao X, Cuento RA, McCoy JP, Cameron CE, Levine SJ, Huang TJ.

Anal Chem. 2016 Jun 7;88(11):5655-61. doi: 10.1021/acs.analchem.5b03383. Epub 2016 May 16.


The global roadmap for advancing development of vaccines against sexually transmitted infections: Update and next steps.

Gottlieb SL, Deal CD, Giersing B, Rees H, Bolan G, Johnston C, Timms P, Gray-Owen SD, Jerse AE, Cameron CE, Moorthy VS, Kiarie J, Broutet N.

Vaccine. 2016 Jun 3;34(26):2939-2947. doi: 10.1016/j.vaccine.2016.03.111. Epub 2016 Apr 19. Review.


Long-Range Communication between Different Functional Sites in the Picornaviral 3C Protein.

Chan YM, Moustafa IM, Arnold JJ, Cameron CE, Boehr DD.

Structure. 2016 Apr 5;24(4):509-517. doi: 10.1016/j.str.2016.02.019.


A Rasch Analysis of the KeyMath-3 Diagnostic Assessment.

Kim H, Schmidt KM, Murrah WM, Cameron CE, Grissmer D.

J Appl Meas. 2015;16(4):365-78.


Conformational Ensemble of the Poliovirus 3CD Precursor Observed by MD Simulations and Confirmed by SAXS: A Strategy to Expand the Viral Proteome?

Moustafa IM, Gohara DW, Uchida A, Yennawar N, Cameron CE.

Viruses. 2015 Nov 23;7(11):5962-86. doi: 10.3390/v7112919. Erratum in: Viruses. 2015 Dec;7(12):6537.


Expression and Purification of Mitochondrial RNA Polymerase and Transcription Factor A from Drosophila melanogaster.

Gajewski JP, Arnold JJ, Salminen TS, Kaguni LS, Cameron CE.

Methods Mol Biol. 2016;1351:199-210. doi: 10.1007/978-1-4939-3040-1_15.

Supplemental Content

Loading ...
Support Center