Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 310

1.

Cas9 Allosteric Inhibition by the Anti-CRISPR Protein AcrIIA6.

Fuchsbauer O, Swuec P, Zimberger C, Amigues B, Levesque S, Agudelo D, Duringer A, Chaves-Sanjuan A, Spinelli S, Rousseau GM, Velimirovic M, Bolognesi M, Roussel A, Cambillau C, Moineau S, Doyon Y, Goulet A.

Mol Cell. 2019 Sep 26. pii: S1097-2765(19)30697-5. doi: 10.1016/j.molcel.2019.09.012. [Epub ahead of print]

PMID:
31604602
2.

Ubiquitous Carbohydrate Binding Modules Decorate 936 Lactococcal Siphophage Virions.

Hayes S, Mahony J, Vincentelli R, Ramond L, Nauta A, van Sinderen D, Cambillau C.

Viruses. 2019 Jul 9;11(7). pii: E631. doi: 10.3390/v11070631.

3.

High-Throughput Protein Production Combined with High- Throughput SELEX Identifies an Extensive Atlas of Ciona robusta Transcription Factor DNA-Binding Specificities.

Nitta KR, Vincentelli R, Jacox E, Cimino A, Ohtsuka Y, Sobral D, Satou Y, Cambillau C, Lemaire P.

Methods Mol Biol. 2019;2025:487-517. doi: 10.1007/978-1-4939-9624-7_23.

PMID:
31267468
4.

Structure of the type VI secretion system TssK-TssF-TssG baseplate subcomplex revealed by cryo-electron microscopy.

Park YJ, Lacourse KD, Cambillau C, DiMaio F, Mougous JD, Veesler D.

Nat Commun. 2018 Dec 19;9(1):5385. doi: 10.1038/s41467-018-07796-5.

5.

Identification of Dual Receptor Binding Protein Systems in Lactococcal 936 Group Phages.

Hayes S, Duhoo Y, Neve H, Murphy J, Noben JP, Franz CMAP, Cambillau C, Mahony J, Nauta A, van Sinderen D.

Viruses. 2018 Nov 27;10(12). pii: E668. doi: 10.3390/v10120668.

6.

Biochemical and Structural Characterization of TesA, a Major Thioesterase Required for Outer-Envelope Lipid Biosynthesis in Mycobacterium tuberculosis.

Nguyen PC, Nguyen VS, Martin BP, Fourquet P, Camoin L, Spilling CD, Cavalier JF, Cambillau C, Canaan S.

J Mol Biol. 2018 Dec 7;430(24):5120-5136. doi: 10.1016/j.jmb.2018.09.017. Epub 2018 Oct 4.

PMID:
30292819
7.

Functional carbohydrate binding modules identified in evolved dits from siphophages infecting various Gram-positive bacteria.

Hayes S, Vincentelli R, Mahony J, Nauta A, Ramond L, Lugli GA, Ventura M, van Sinderen D, Cambillau C.

Mol Microbiol. 2018 Dec;110(5):777-795. doi: 10.1111/mmi.14124. Epub 2018 Oct 30.

PMID:
30204278
8.

Widespread anti-CRISPR proteins in virulent bacteriophages inhibit a range of Cas9 proteins.

Hynes AP, Rousseau GM, Agudelo D, Goulet A, Amigues B, Loehr J, Romero DA, Fremaux C, Horvath P, Doyon Y, Cambillau C, Moineau S.

Nat Commun. 2018 Jul 25;9(1):2919. doi: 10.1038/s41467-018-05092-w.

9.

The gp27-like Hub of VgrG Serves as Adaptor to Promote Hcp Tube Assembly.

Renault MG, Zamarreno Beas J, Douzi B, Chabalier M, Zoued A, Brunet YR, Cambillau C, Journet L, Cascales E.

J Mol Biol. 2018 Sep 14;430(18 Pt B):3143-3156. doi: 10.1016/j.jmb.2018.07.018. Epub 2018 Jul 19.

PMID:
30031895
10.

A Decade of Streptococcus thermophilus Phage Evolution in an Irish Dairy Plant.

Lavelle K, Murphy J, Fitzgerald B, Lugli GA, Zomer A, Neve H, Ventura M, Franz CM, Cambillau C, van Sinderen D, Mahony J.

Appl Environ Microbiol. 2018 May 1;84(10). pii: e02855-17. doi: 10.1128/AEM.02855-17. Print 2018 May 15.

11.

Towards a complete structural deciphering of Type VI secretion system.

Nguyen VS, Douzi B, Durand E, Roussel A, Cascales E, Cambillau C.

Curr Opin Struct Biol. 2018 Apr;49:77-84. doi: 10.1016/j.sbi.2018.01.007. Epub 2018 Feb 2. Review.

PMID:
29414515
12.

Type IX secretion system PorM and gliding machinery GldM form arches spanning the periplasmic space.

Leone P, Roche J, Vincent MS, Tran QH, Desmyter A, Cascales E, Kellenberger C, Cambillau C, Roussel A.

Nat Commun. 2018 Jan 30;9(1):429. doi: 10.1038/s41467-017-02784-7.

13.

Structure-Function Analysis of the C-Terminal Domain of the Type VI Secretion TssB Tail Sheath Subunit.

Douzi B, Logger L, Spinelli S, Blangy S, Cambillau C, Cascales E.

J Mol Biol. 2018 Feb 2;430(3):297-309. doi: 10.1016/j.jmb.2017.11.015. Epub 2017 Dec 6.

PMID:
29223729
14.

ANISEED 2017: extending the integrated ascidian database to the exploration and evolutionary comparison of genome-scale datasets.

Brozovic M, Dantec C, Dardaillon J, Dauga D, Faure E, Gineste M, Louis A, Naville M, Nitta KR, Piette J, Reeves W, Scornavacca C, Simion P, Vincentelli R, Bellec M, Aicha SB, Fagotto M, Guéroult-Bellone M, Haeussler M, Jacox E, Lowe EK, Mendez M, Roberge A, Stolfi A, Yokomori R, Brown CT, Cambillau C, Christiaen L, Delsuc F, Douzery E, Dumollard R, Kusakabe T, Nakai K, Nishida H, Satou Y, Swalla B, Veeman M, Volff JN, Lemaire P.

Nucleic Acids Res. 2018 Jan 4;46(D1):D718-D725. doi: 10.1093/nar/gkx1108.

15.

Reverse chemical ecology: Olfactory proteins from the giant panda and their interactions with putative pheromones and bamboo volatiles.

Zhu J, Arena S, Spinelli S, Liu D, Zhang G, Wei R, Cambillau C, Scaloni A, Wang G, Pelosi P.

Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):E9802-E9810. doi: 10.1073/pnas.1711437114. Epub 2017 Oct 23.

16.

Unraveling the Self-Assembly of the Pseudomonas aeruginosa XcpQ Secretin Periplasmic Domain Provides New Molecular Insights into Type II Secretion System Secreton Architecture and Dynamics.

Douzi B, Trinh NTT, Michel-Souzy S, Desmyter A, Ball G, Barbier P, Kosta A, Durand E, Forest KT, Cambillau C, Roussel A, Voulhoux R.

MBio. 2017 Oct 17;8(5). pii: e01185-17. doi: 10.1128/mBio.01185-17.

17.

Neutralization of Human Interleukin 23 by Multivalent Nanobodies Explained by the Structure of Cytokine-Nanobody Complex.

Desmyter A, Spinelli S, Boutton C, Saunders M, Blachetot C, de Haard H, Denecker G, Van Roy M, Cambillau C, Rommelaere H.

Front Immunol. 2017 Aug 21;8:884. doi: 10.3389/fimmu.2017.00884. eCollection 2017.

18.

Host recognition by lactic acid bacterial phages.

Mahony J, Cambillau C, van Sinderen D.

FEMS Microbiol Rev. 2017 Aug 1;41(Supp_1):S16-S26. doi: 10.1093/femsre/fux019. Review.

PMID:
28830088
19.

Bivalent Llama Single-Domain Antibody Fragments against Tumor Necrosis Factor Have Picomolar Potencies due to Intramolecular Interactions.

Beirnaert E, Desmyter A, Spinelli S, Lauwereys M, Aarden L, Dreier T, Loris R, Silence K, Pollet C, Cambillau C, de Haard H.

Front Immunol. 2017 Jul 31;8:867. doi: 10.3389/fimmu.2017.00867. eCollection 2017.

20.

TssA: The cap protein of the Type VI secretion system tail.

Zoued A, Durand E, Santin YG, Journet L, Roussel A, Cambillau C, Cascales E.

Bioessays. 2017 Oct;39(10). doi: 10.1002/bies.201600262. Epub 2017 Aug 17. Review.

PMID:
28817192
21.

Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex.

Nguyen VS, Logger L, Spinelli S, Legrand P, Huyen Pham TT, Nhung Trinh TT, Cherrak Y, Zoued A, Desmyter A, Durand E, Roussel A, Kellenberger C, Cascales E, Cambillau C.

Nat Microbiol. 2017 Jun 26;2:17103. doi: 10.1038/nmicrobiol.2017.103.

PMID:
28650463
22.

Camelid nanobodies used as crystallization chaperones for different constructs of PorM, a component of the type IX secretion system from Porphyromonas gingivalis.

Duhoo Y, Roche J, Trinh TTN, Desmyter A, Gaubert A, Kellenberger C, Cambillau C, Roussel A, Leone P.

Acta Crystallogr F Struct Biol Commun. 2017 May 1;73(Pt 5):286-293. doi: 10.1107/S2053230X17005969. Epub 2017 Apr 26.

23.

Evolved distal tail carbohydrate binding modules of Lactobacillus phage J-1: a novel type of anti-receptor widespread among lactic acid bacteria phages.

Dieterle ME, Spinelli S, Sadovskaya I, Piuri M, Cambillau C.

Mol Microbiol. 2017 May;104(4):608-620. doi: 10.1111/mmi.13649. Epub 2017 Mar 6.

24.

Genetic and functional characterisation of the lactococcal P335 phage-host interactions.

Mahony J, Oliveira J, Collins B, Hanemaaijer L, Lugli GA, Neve H, Ventura M, Kouwen TR, Cambillau C, van Sinderen D.

BMC Genomics. 2017 Feb 10;18(1):146. doi: 10.1186/s12864-017-3537-5.

25.

Probing Conformational Changes and Interfacial Recognition Site of Lipases With Surfactants and Inhibitors.

Mateos-Diaz E, Amara S, Roussel A, Longhi S, Cambillau C, Carrière F.

Methods Enzymol. 2017;583:279-307. doi: 10.1016/bs.mie.2016.09.040. Epub 2016 Nov 11.

PMID:
28063495
26.

Characterization of the Porphyromonas gingivalis Type IX Secretion Trans-envelope PorKLMNP Core Complex.

Vincent MS, Canestrari MJ, Leone P, Stathopulos J, Ize B, Zoued A, Cambillau C, Kellenberger C, Roussel A, Cascales E.

J Biol Chem. 2017 Feb 24;292(8):3252-3261. doi: 10.1074/jbc.M116.765081. Epub 2017 Jan 5.

27.

Functional and structural dissection of the tape measure protein of lactococcal phage TP901-1.

Mahony J, Alqarni M, Stockdale S, Spinelli S, Feyereisen M, Cambillau C, Sinderen DV.

Sci Rep. 2016 Nov 8;6:36667. doi: 10.1038/srep36667.

28.

Structure-Function Analysis of the TssL Cytoplasmic Domain Reveals a New Interaction between the Type VI Secretion Baseplate and Membrane Complexes.

Zoued A, Cassaro CJ, Durand E, Douzi B, España AP, Cambillau C, Journet L, Cascales E.

J Mol Biol. 2016 Nov 6;428(22):4413-4423. doi: 10.1016/j.jmb.2016.08.030. Epub 2016 Sep 4.

PMID:
27600409
29.

Structure and specificity of the Type VI secretion system ClpV-TssC interaction in enteroaggregative Escherichia coli.

Douzi B, Brunet YR, Spinelli S, Lensi V, Legrand P, Blangy S, Kumar A, Journet L, Cascales E, Cambillau C.

Sci Rep. 2016 Oct 4;6:34405. doi: 10.1038/srep34405.

30.

Characterization of prophages containing "evolved" Dit/Tal modules in the genome of Lactobacillus casei BL23.

Dieterle ME, Fina Martin J, Durán R, Nemirovsky SI, Sanchez Rivas C, Bowman C, Russell D, Hatfull GF, Cambillau C, Piuri M.

Appl Microbiol Biotechnol. 2016 Nov;100(21):9201-9215. Epub 2016 Jul 23.

PMID:
27448399
31.

Structure of the host-recognition device of Staphylococcus aureus phage ϕ11.

Koç C, Xia G, Kühner P, Spinelli S, Roussel A, Cambillau C, Stehle T.

Sci Rep. 2016 Jun 10;6:27581. doi: 10.1038/srep27581.

32.

The Baseplate of Lactobacillus delbrueckii Bacteriophage Ld17 Harbors a Glycerophosphodiesterase.

Cornelissen A, Sadovskaya I, Vinogradov E, Blangy S, Spinelli S, Casey E, Mahony J, Noben JP, Dal Bello F, Cambillau C, van Sinderen D.

J Biol Chem. 2016 Aug 5;291(32):16816-27. doi: 10.1074/jbc.M116.728279. Epub 2016 Jun 6.

33.

An essential role for the baseplate protein Gp45 in phage adsorption to Staphylococcus aureus.

Li X, Koç C, Kühner P, Stierhof YD, Krismer B, Enright MC, Penadés JR, Wolz C, Stehle T, Cambillau C, Peschel A, Xia G.

Sci Rep. 2016 May 23;6:26455. doi: 10.1038/srep26455.

34.

Lactococcus lactis phage TP901-1 as a model for Siphoviridae virion assembly.

Mahony J, Stockdale SR, Collins B, Spinelli S, Douillard FP, Cambillau C, van Sinderen D.

Bacteriophage. 2016 Jan 6;6(1):e1123795. eCollection 2016 Jan-Mar.

35.

Structural Mimicry of Receptor Interaction by Antagonistic Interleukin-6 (IL-6) Antibodies.

Blanchetot C, De Jonge N, Desmyter A, Ongenae N, Hofman E, Klarenbeek A, Sadi A, Hultberg A, Kretz-Rommel A, Spinelli S, Loris R, Cambillau C, de Haard H.

J Biol Chem. 2016 Jun 24;291(26):13846-54. doi: 10.1074/jbc.M115.695528. Epub 2016 Apr 27.

36.

Combining somatic mutations present in different in vivo affinity-matured antibodies isolated from immunized Lama glama yields ultra-potent antibody therapeutics.

Klarenbeek A, Blanchetot C, Schragel G, Sadi AS, Ongenae N, Hemrika W, Wijdenes J, Spinelli S, Desmyter A, Cambillau C, Hultberg A, Kretz-Rommel A, Dreier T, De Haard HJ, Roovers RC.

Protein Eng Des Sel. 2016 Apr;29(4):123-33. doi: 10.1093/protein/gzw003. Epub 2016 Mar 5.

PMID:
26945588
37.

Priming and polymerization of a bacterial contractile tail structure.

Zoued A, Durand E, Brunet YR, Spinelli S, Douzi B, Guzzo M, Flaugnatti N, Legrand P, Journet L, Fronzes R, Mignot T, Cambillau C, Cascales E.

Nature. 2016 Mar 3;531(7592):59-63. doi: 10.1038/nature17182. Epub 2016 Feb 24.

PMID:
26909579
38.

The Atomic Structure of the Phage Tuc2009 Baseplate Tripod Suggests that Host Recognition Involves Two Different Carbohydrate Binding Modules.

Legrand P, Collins B, Blangy S, Murphy J, Spinelli S, Gutierrez C, Richet N, Kellenberger C, Desmyter A, Mahony J, van Sinderen D, Cambillau C.

MBio. 2016 Jan 26;7(1):e01781-15. doi: 10.1128/mBio.01781-15.

39.

A phospholipase A1 antibacterial Type VI secretion effector interacts directly with the C-terminal domain of the VgrG spike protein for delivery.

Flaugnatti N, Le TT, Canaan S, Aschtgen MS, Nguyen VS, Blangy S, Kellenberger C, Roussel A, Cambillau C, Cascales E, Journet L.

Mol Microbiol. 2016 Mar;99(6):1099-118. doi: 10.1111/mmi.13292. Epub 2016 Feb 10.

40.

Biogenesis and structure of a type VI secretion membrane core complex.

Durand E, Nguyen VS, Zoued A, Logger L, Péhau-Arnaudet G, Aschtgen MS, Spinelli S, Desmyter A, Bardiaux B, Dujeancourt A, Roussel A, Cambillau C, Cascales E, Fronzes R.

Nature. 2015 Jul 30;523(7562):555-60. doi: 10.1038/nature14667. Epub 2015 Jul 22.

41.

Structure and Assembly of TP901-1 Virion Unveiled by Mutagenesis.

Stockdale SR, Collins B, Spinelli S, Douillard FP, Mahony J, Cambillau C, van Sinderen D.

PLoS One. 2015 Jul 6;10(7):e0131676. doi: 10.1371/journal.pone.0131676. eCollection 2015.

42.

Bacteriophage module reshuffling results in adaptive host range as exemplified by the baseplate model of listerial phage A118.

Cambillau C.

Virology. 2015 Oct;484:86-92. doi: 10.1016/j.virol.2015.05.015. Epub 2015 Jun 15.

43.

Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform.

Klarenbeek A, El Mazouari K, Desmyter A, Blanchetot C, Hultberg A, de Jonge N, Roovers RC, Cambillau C, Spinelli S, Del-Favero J, Verrips T, de Haard HJ, Achour I.

MAbs. 2015;7(4):693-706. doi: 10.1080/19420862.2015.1046648.

44.

X-ray and Cryo-electron Microscopy Structures of Monalysin Pore-forming Toxin Reveal Multimerization of the Pro-form.

Leone P, Bebeacua C, Opota O, Kellenberger C, Klaholz B, Orlov I, Cambillau C, Lemaitre B, Roussel A.

J Biol Chem. 2015 May 22;290(21):13191-201. doi: 10.1074/jbc.M115.646109. Epub 2015 Apr 5.

45.

Inhibition of type VI secretion by an anti-TssM llama nanobody.

Nguyen VS, Logger L, Spinelli S, Desmyter A, Le TT, Kellenberger C, Douzi B, Durand E, Roussel A, Cascales E, Cambillau C.

PLoS One. 2015 Mar 26;10(3):e0122187. doi: 10.1371/journal.pone.0122187. eCollection 2015.

46.

Production, crystallization and X-ray diffraction analysis of a complex between a fragment of the TssM T6SS protein and a camelid nanobody.

Nguyen VS, Spinelli S, Desmyter A, Le TT, Kellenberger C, Cascales E, Cambillau C, Roussel A.

Acta Crystallogr F Struct Biol Commun. 2015 Mar;71(Pt 3):266-71. doi: 10.1107/S2053230X15000709. Epub 2015 Feb 19.

47.

The targeted recognition of Lactococcus lactis phages to their polysaccharide receptors.

McCabe O, Spinelli S, Farenc C, Labbé M, Tremblay D, Blangy S, Oscarson S, Moineau S, Cambillau C.

Mol Microbiol. 2015 May;96(4):875-86. doi: 10.1111/mmi.12978. Epub 2015 Mar 16.

48.

Crystallization and preliminary X-ray analysis of the C-terminal fragment of PorM, a subunit of the Porphyromonas gingivalis type IX secretion system.

Stathopulos J, Cambillau C, Cascales E, Roussel A, Leone P.

Acta Crystallogr F Struct Biol Commun. 2015 Jan 1;71(Pt 1):71-4. doi: 10.1107/S2053230X1402559X. Epub 2015 Jan 1.

49.

Camelid nanobodies: killing two birds with one stone.

Desmyter A, Spinelli S, Roussel A, Cambillau C.

Curr Opin Struct Biol. 2015 Jun;32:1-8. doi: 10.1016/j.sbi.2015.01.001. Epub 2015 Jan 19. Review.

PMID:
25614146
50.

A Cutinase from Trichoderma reesei with a lid-covered active site and kinetic properties of true lipases.

Roussel A, Amara S, Nyyssölä A, Mateos-Diaz E, Blangy S, Kontkanen H, Westerholm-Parvinen A, Carrière F, Cambillau C.

J Mol Biol. 2014 Nov 11;426(22):3757-3772. doi: 10.1016/j.jmb.2014.09.003. Epub 2014 Sep 16.

PMID:
25219509

Supplemental Content

Loading ...
Support Center