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Comparative analysis of novel decynium-22 analogs to inhibit transport by the low-affinity, high-capacity monoamine transporters, organic cation transporters 2 and 3, and plasma membrane monoamine transporter.

Fraser-Spears R, Krause-Heuer AM, Basiouny M, Mayer FP, Manishimwe R, Wyatt NA, Dobrowolski JC, Roberts MP, Greguric I, Kumar N, Koek W, Sitte HH, Callaghan PD, Fraser BH, Daws LC.

Eur J Pharmacol. 2019 Jan 5;842:351-364. doi: 10.1016/j.ejphar.2018.10.028. Epub 2018 Oct 25.


Embedding shared decision-making in the care of patients with severe and enduring mental health problems: The EQUIP pragmatic cluster randomised trial.

Lovell K, Bee P, Brooks H, Cahoon P, Callaghan P, Carter LA, Cree L, Davies L, Drake R, Fraser C, Gibbons C, Grundy A, Hinsliff-Smith K, Meade O, Roberts C, Rogers A, Rushton K, Sanders C, Shields G, Walker L, Bower P.

PLoS One. 2018 Aug 22;13(8):e0201533. doi: 10.1371/journal.pone.0201533. eCollection 2018.


A stratospheric pathway linking a colder Siberia to Barents-Kara Sea sea ice loss.

Zhang P, Wu Y, Simpson IR, Smith KL, Zhang X, De B, Callaghan P.

Sci Adv. 2018 Jul 25;4(7):eaat6025. doi: 10.1126/sciadv.aat6025. eCollection 2018 Jul.


The concept of compassion within UK media-generated discourse: A corpus-informed analysis.

Bond C, Stacey G, Field-Richards S, Callaghan P, Keeley P, Lymn J, Redsell S, Spiby H.

J Clin Nurs. 2018 Aug;27(15-16):3081-3090. doi: 10.1111/jocn.14496. Epub 2018 Jun 20.


An exploration of predictors of children's nurses' attitudes, knowledge, confidence and clinical behavioural intentions towards children and young people who self-harm.

Carter T, Latif A, Callaghan P, Manning JC.

J Clin Nurs. 2018 Jul;27(13-14):2836-2846. doi: 10.1111/jocn.14361. Epub 2018 Apr 19.


Monitoring oral health of people in Early Intervention for Psychosis (EIP) teams: The extended Three Shires randomised trial.

Adams CE, Wells NC, Clifton A, Jones H, Simpson J, Tosh G, Callaghan P, Liddle P, Guo B, Furtado V, Khokhar MA, Aggarwal VR.

Int J Nurs Stud. 2018 Jan;77:106-114. doi: 10.1016/j.ijnurstu.2017.10.005. Epub 2017 Oct 16.


Analysis of Plasmodium vivax Chloroquine Resistance Transporter Mutant Isoforms.

Hassett MR, Riegel BE, Callaghan PS, Roepe PD.

Biochemistry. 2017 Oct 17;56(41):5615-5622. doi: 10.1021/acs.biochem.7b00749. Epub 2017 Sep 26.


Evaluation of the antidepressant therapeutic potential of isocyanine and pseudoisocyanine analogues of the organic cation decynium-22.

Krause-Heuer AM, Fraser-Spears R, Dobrowolski JC, Ashford ME, Wyatt NA, Roberts MP, Gould GG, Cheah WC, Ng CKL, Bhadbhade M, Zhang B, Greguric I, Wheate NJ, Kumar N, Koek W, Callaghan PD, Daws LC, Fraser BH.

Eur J Med Chem. 2017 Sep 8;137:476-487. doi: 10.1016/j.ejmech.2017.06.011. Epub 2017 Jun 7.


'Our Care through Our Eyes'. Impact of a co-produced digital educational programme on nurses' knowledge, confidence and attitudes in providing care for children and young people who have self-harmed: a mixed-methods study in the UK.

Manning JC, Carter T, Latif A, Horsley A, Cooper J, Armstrong M, Crew J, Wood D, Callaghan P, Wharrad H.

BMJ Open. 2017 May 4;7(4):e014750. doi: 10.1136/bmjopen-2016-014750.


Bioaccumulation and Biodistribution of Selenium in Metamorphosing Tadpoles.

Lanctôt CM, Cresswell T, Callaghan PD, Melvin SD.

Environ Sci Technol. 2017 May 16;51(10):5764-5773. doi: 10.1021/acs.est.7b00300. Epub 2017 Apr 27.


Metal Transfer among Organs Following Short- and Long-Term Exposures Using Autoradiography: Cadmium Bioaccumulation by the Freshwater Prawn Macrobrachium australiense.

Cresswell T, Mazumder D, Callaghan PD, Nguyen A, Corry M, Simpson SL.

Environ Sci Technol. 2017 Apr 4;51(7):4054-4060. doi: 10.1021/acs.est.6b06471. Epub 2017 Mar 24.


The Differential Binding of Antipsychotic Drugs to the ABC Transporter P-Glycoprotein Predicts Cannabinoid-Antipsychotic Drug Interactions.

Brzozowska NI, de Tonnerre EJ, Li KM, Wang XS, Boucher AA, Callaghan PD, Kuligowski M, Wong A, Arnold JC.

Neuropsychopharmacology. 2017 Oct;42(11):2222-2231. doi: 10.1038/npp.2017.50. Epub 2017 Mar 8.


Evaluation of a co-delivered training package for community mental health professionals on service user- and carer-involved care planning.

Grundy AC, Walker L, Meade O, Fraser C, Cree L, Bee P, Lovell K, Callaghan P.

J Psychiatr Ment Health Nurs. 2017 Aug;24(6):358-366. doi: 10.1111/jpm.12378. Epub 2017 Apr 27.


EQUIP training the trainers: an evaluation of a training programme for service users and carers involved in training mental health professionals in user-involved care planning.

Fraser C, Grundy A, Meade O, Callaghan P, Lovell K.

J Psychiatr Ment Health Nurs. 2017 Aug;24(6):367-376. doi: 10.1111/jpm.12361. Epub 2017 Jan 20.


Behavioural Activation Therapy for Depression after Stroke (BEADS): a study protocol for a feasibility randomised controlled pilot trial of a psychological intervention for post-stroke depression.

Thomas SA, Coates E, das Nair R, Lincoln NB, Cooper C, Palmer R, Walters SJ, Latimer NR, England TJ, Mandefield L, Chater T, Callaghan P, Drummond AE.

Pilot Feasibility Stud. 2016 Aug 10;2:45. eCollection 2016.


The impact of advertising patient and public involvement on trial recruitment: embedded cluster randomised recruitment trial.

Hughes-Morley A, Hann M, Fraser C, Meade O, Lovell K, Young B, Roberts C, Cree L, More D, O'Leary N, Callaghan P, Waheed W, Bower P.

Trials. 2016 Dec 8;17(1):586.


Evolution of Fitness Cost-Neutral Mutant PfCRT Conferring P. falciparum 4-Aminoquinoline Drug Resistance Is Accompanied by Altered Parasite Metabolism and Digestive Vacuole Physiology.

Gabryszewski SJ, Dhingra SK, Combrinck JM, Lewis IA, Callaghan PS, Hassett MR, Siriwardana A, Henrich PP, Lee AH, Gnädig NF, Musset L, Llinás M, Egan TJ, Roepe PD, Fidock DA.

PLoS Pathog. 2016 Nov 10;12(11):e1005976. doi: 10.1371/journal.ppat.1005976. eCollection 2016 Nov.


The effectiveness of the Penn Resiliency Programme (PRP) and its adapted versions in reducing depression and anxiety and improving explanatory style: A systematic review and meta-analysis.

Bastounis A, Callaghan P, Banerjee A, Michail M.

J Adolesc. 2016 Oct;52:37-48. doi: 10.1016/j.adolescence.2016.07.004. Epub 2016 Aug 2. Review.


The Effect of Exercise on Depressive Symptoms in Adolescents: A Systematic Review and Meta-Analysis.

Carter T, Morres ID, Meade O, Callaghan P.

J Am Acad Child Adolesc Psychiatry. 2016 Jul;55(7):580-90. doi: 10.1016/j.jaac.2016.04.016. Epub 2016 May 10. Review.


Plasmodium falciparum chloroquine resistance transporter (PfCRT) isoforms PH1 and PH2 perturb vacuolar physiology.

Callaghan PS, Siriwardana A, Hassett MR, Roepe PD.

Malar J. 2016 Mar 31;15:186. doi: 10.1186/s12936-016-1238-1.


Evaluating and Quantifying User and Carer Involvement in Mental Health Care Planning (EQUIP): Co-Development of a New Patient-Reported Outcome Measure.

Bee P, Gibbons C, Callaghan P, Fraser C, Lovell K.

PLoS One. 2016 Mar 10;11(3):e0149973. doi: 10.1371/journal.pone.0149973. eCollection 2016.


OSSI-PET: Open-Access Database of Simulated [(11)C]Raclopride Scans for the Inveon Preclinical PET Scanner: Application to the Optimization of Reconstruction Methods for Dynamic Studies.

Garcia MP, Charil A, Callaghan P, Wimberley C, Busso F, Gregoire MC, Bardies M, Reilhac A.

IEEE Trans Med Imaging. 2016 Jul;35(7):1696-706. doi: 10.1109/TMI.2016.2526086. Epub 2016 Feb 5.


Citizens' Perspectives on Disinvestment from Publicly Funded Pathology Tests: A Deliberative Forum.

Street JM, Callaghan P, Braunack-Mayer AJ, Hiller JE.

Value Health. 2015 Dec;18(8):1050-6. doi: 10.1016/j.jval.2015.05.012. Epub 2015 Nov 2.


Bringing meaning to user involvement in mental health care planning: a qualitative exploration of service user perspectives.

Grundy AC, Bee P, Meade O, Callaghan P, Beatty S, Olleveant N, Lovell K.

J Psychiatr Ment Health Nurs. 2016 Feb;23(1):12-21. doi: 10.1111/jpm.12275. Epub 2015 Dec 3.


Preferred intensity exercise for adolescents receiving treatment for depression: a pragmatic randomised controlled trial.

Carter T, Guo B, Turner D, Morres I, Khalil E, Brighton E, Armstrong M, Callaghan P.

BMC Psychiatry. 2015 Oct 14;15:247. doi: 10.1186/s12888-015-0638-z.


Managing preconceived expectations: mental health service users experiences of going home from hospital: a grounded theory study.

Keogh B, Callaghan P, Higgins A.

J Psychiatr Ment Health Nurs. 2015 Nov;22(9):715-23. doi: 10.1111/jpm.12265. Epub 2015 Aug 24.


Exercise for adolescents with depression: valued aspects and perceived change.

Carter T, Morres I, Repper J, Callaghan P.

J Psychiatr Ment Health Nurs. 2016 Feb;23(1):37-44. doi: 10.1111/jpm.12261. Epub 2015 Aug 19.


A cluster randomised controlled trial and process evaluation of a training programme for mental health professionals to enhance user involvement in care planning in service users with severe mental health issues (EQUIP): study protocol for a randomised controlled trial.

Bower P, Roberts C, O'Leary N, Callaghan P, Bee P, Fraser C, Gibbons C, Olleveant N, Rogers A, Davies L, Drake R, Sanders C, Meade O, Grundy A, Walker L, Cree L, Berzins K, Brooks H, Beatty S, Cahoon P, Rolfe A, Lovell K.

Trials. 2015 Aug 13;16:348. doi: 10.1186/s13063-015-0896-6.


Functional Comparison of 45 Naturally Occurring Isoforms of the Plasmodium falciparum Chloroquine Resistance Transporter (PfCRT).

Callaghan PS, Hassett MR, Roepe PD.

Biochemistry. 2015 Aug 18;54(32):5083-94. doi: 10.1021/acs.biochem.5b00412. Epub 2015 Aug 6.


4D PET iterative deconvolution with spatiotemporal regularization for quantitative dynamic PET imaging.

Reilhac A, Charil A, Wimberley C, Angelis G, Hamze H, Callaghan P, Garcia MP, Boisson F, Ryder W, Meikle SR, Gregoire MC.

Neuroimage. 2015 Sep;118:484-93. doi: 10.1016/j.neuroimage.2015.06.029. Epub 2015 Jun 14.


Bioaccumulation kinetics and organ distribution of cadmium and zinc in the freshwater decapod crustacean Macrobrachium australiense.

Cresswell T, Simpson SL, Mazumder D, Callaghan PD, Nguyen AP.

Environ Sci Technol. 2015 Jan 20;49(2):1182-9.


The experience of melanoma follow-up care: an online survey of patients in australia.

Mitchell J, Callaghan P, Street J, Neuhaus S, Bessen T.

J Skin Cancer. 2014;2014:429149. doi: 10.1155/2014/429149. Epub 2014 Nov 19.


Positron emission tomography and functional characterization of a complete PBR/TSPO knockout.

Banati RB, Middleton RJ, Chan R, Hatty CR, Kam WW, Quin C, Graeber MB, Parmar A, Zahra D, Callaghan P, Fok S, Howell NR, Gregoire M, Szabo A, Pham T, Davis E, Liu GJ.

Nat Commun. 2014 Nov 19;5:5452. doi: 10.1038/ncomms6452.


Partial genetic deletion of neuregulin 1 and adolescent stress interact to alter NMDA receptor binding in the medial prefrontal cortex.

Chohan TW, Nguyen A, Todd SM, Bennett MR, Callaghan P, Arnold JC.

Front Behav Neurosci. 2014 Sep 29;8:298. doi: 10.3389/fnbeh.2014.00298. eCollection 2014.


Comparison of in vivo binding properties of the 18-kDa translocator protein (TSPO) ligands [(18)F]PBR102 and [ (18)F]PBR111 in a model of excitotoxin-induced neuroinflammation.

Callaghan PD, Wimberley CA, Rahardjo GL, Berghofer PJ, Pham TQ, Jackson T, Zahra D, Bourdier T, Wyatt N, Greguric I, Howell NR, Siegele R, Pastuovic Z, Mattner F, Loc'h C, Gregoire MC, Katsifis A.

Eur J Nucl Med Mol Imaging. 2015 Jan;42(1):138-51. doi: 10.1007/s00259-014-2895-3. Epub 2014 Sep 18.


The strengths based approach as a service delivery model for severe mental illness: a meta-analysis of clinical trials.

Ibrahim N, Michail M, Callaghan P.

BMC Psychiatry. 2014 Aug 29;14:243. doi: 10.1186/s12888-014-0243-6.


Aggression on haemodialysis units: a mixed method study.

Jones J, Nijman H, Ross J, Ashman N, Callaghan P.

J Ren Care. 2014 Sep;40(3):180-93. doi: 10.1111/jorc.12068. Epub 2014 Jul 16.


A mixed methods feasibility study to evaluate the use of a low-intensity, nurse-delivered cognitive behavioural therapy for the treatment of irritable bowel syndrome.

Dainty AD, Fox M, Lewis N, Hunt M, Holtham E, Timmons S, Kinsella P, Wragg A, Callaghan P.

BMJ Open. 2014 Jun 17;4(6):e005262. doi: 10.1136/bmjopen-2014-005262.


Simulation-based optimisation of the PET data processing for partial saturation approach protocols.

Wimberley C, Angelis G, Boisson F, Callaghan P, Fischer K, Pichler BJ, Meikle SR, Grégoire MC, Reilhac A.

Neuroimage. 2014 Aug 15;97:29-40. doi: 10.1016/j.neuroimage.2014.04.010. Epub 2014 Apr 14.


Beyond poiseuille: preservation fluid flow in an experimental model.

Singh S, Randle LV, Callaghan PT, Watson CJ, Callaghan CJ.

J Transplant. 2013;2013:605326. doi: 10.1155/2013/605326. Epub 2013 Aug 26.


UV-triggered affinity capture identifies interactions between the Plasmodium falciparum multidrug resistance protein 1 (PfMDR1) and antimalarial agents in live parasitized cells.

Brunner R, Ng CL, Aissaoui H, Akabas MH, Boss C, Brun R, Callaghan PS, Corminboeuf O, Fidock DA, Frame IJ, Heidmann B, Le Bihan A, Jenö P, Mattheis C, Moes S, Müller IB, Paguio M, Roepe PD, Siegrist R, Voss T, Welford RW, Wittlin S, Binkert C.

J Biol Chem. 2013 Aug 2;288(31):22576-83. doi: 10.1074/jbc.M113.453159. Epub 2013 Jun 10.


High levels of intravenous mephedrone (4-methylmethcathinone) self-administration in rats: neural consequences and comparison with methamphetamine.

Motbey CP, Clemens KJ, Apetz N, Winstock AR, Ramsey J, Li KM, Wyatt N, Callaghan PD, Bowen MT, Cornish JL, McGregor IS.

J Psychopharmacol. 2013 Sep;27(9):823-36. doi: 10.1177/0269881113490325. Epub 2013 Jun 5.


An oral health intervention for people with serious mental illness (Three Shires Early Intervention Dental Trial): study protocol for a randomised controlled trial.

Jones HF, Adams CE, Clifton A, Simpson J, Tosh G, Liddle PF, Callaghan P, Yang M, Guo B, Furtado V.

Trials. 2013 May 29;14:158. doi: 10.1186/1745-6215-14-158.


Function of resistance conferring Plasmodium falciparum chloroquine resistance transporter isoforms.

Baro NK, Callaghan PS, Roepe PD.

Biochemistry. 2013 Jun 18;52(24):4242-9. doi: 10.1021/bi400557x. Epub 2013 Jun 6.


'We have got the tools': Qualitative evaluation of a mental health Wellness Recovery Action Planning (WRAP) education programme in Ireland.

Keogh B, Higgins A, Devries J, Morrissey J, Callaghan P, Ryan D, Gijbels H, Nash M.

J Psychiatr Ment Health Nurs. 2014 Apr;21(3):189-96. doi: 10.1111/jpm.12068. Epub 2013 Apr 1.


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