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Items: 1 to 50 of 387

1.

Trisomy 12 chronic lymphocytic leukemia expresses a unique set of activated and targetable pathways.

Abruzzo LV, Herling CD, Calin GA, Oakes C, Barron LL, Banks HE, Katju V, Keating MJ, Coombes KR.

Haematologica. 2018 Jul 5. pii: haematol.2018.190132. doi: 10.3324/haematol.2018.190132. [Epub ahead of print]

2.

Thymoquinone inhibits cell proliferation, migration, and invasion by regulating the elongation factor 2 kinase (eEF-2K) signaling axis in triple-negative breast cancer.

Kabil N, Bayraktar R, Kahraman N, Mokhlis HA, Calin GA, Lopez-Berestein G, Ozpolat B.

Breast Cancer Res Treat. 2018 Jul 3. doi: 10.1007/s10549-018-4847-2. [Epub ahead of print]

PMID:
29971628
3.

Key questions about the checkpoint blockade-are microRNAs an answer?

Dragomir M, Chen B, Fu X, Calin GA.

Cancer Biol Med. 2018 May;15(2):103-115. doi: 10.20892/j.issn.2095-3941.2018.0006.

4.

Using microRNA Networks to Understand Cancer.

Dragomir M, Mafra ACP, Dias SMG, Vasilescu C, Calin GA.

Int J Mol Sci. 2018 Jun 26;19(7). pii: E1871. doi: 10.3390/ijms19071871. Review.

5.

Circular RNAs in Cancer - Lessons Learned From microRNAs.

Dragomir M, Calin GA.

Front Oncol. 2018 May 28;8:179. doi: 10.3389/fonc.2018.00179. eCollection 2018. Review.

6.

Clinical utility of circulating non-coding RNAs - an update.

Anfossi S, Babayan A, Pantel K, Calin GA.

Nat Rev Clin Oncol. 2018 May 21. doi: 10.1038/s41571-018-0035-x. [Epub ahead of print] Review.

PMID:
29784926
7.

MicroRNAs, Regulatory Messengers Inside and Outside Cancer Cells.

Anfossi S, Fu X, Nagvekar R, Calin GA.

Adv Exp Med Biol. 2018;1056:87-108. doi: 10.1007/978-3-319-74470-4_6.

PMID:
29754176
8.

Dual suppressive effect of microRNA-34a on the FOXM1/eEF2-kinase axis regulates triple-negative breast cancer growth and invasion.

Bayraktar R, Ivan C, Bayraktar E, Kanlikilicer P, Kabil N, Kahraman N, Mokhlis HA, Karakas D, Rodriguez-Aguayo C, Arslan A, Sheng J, Wong ST, Lopez-Berestein G, Calin GA, Ozpolat B.

Clin Cancer Res. 2018 May 10. pii: clincanres.1959.2017. doi: 10.1158/1078-0432.CCR-17-1959. [Epub ahead of print]

PMID:
29748184
9.

Trastuzumab upregulates PD-L1 as a potential mechanism of trastuzumab resistance through engagement of immune effector cells and stimulation of IFNγ secretion.

Chaganty BKR, Qiu S, Gest A, Lu Y, Ivan C, Calin GA, Weiner LM, Fan Z.

Cancer Lett. 2018 Aug 28;430:47-56. doi: 10.1016/j.canlet.2018.05.009. Epub 2018 May 8.

PMID:
29746929
10.

Cancer-associated rs6983267 SNP and its accompanying long noncoding RNA CCAT2 induce myeloid malignancies via unique SNP-specific RNA mutations.

Shah MY, Ferracin M, Pileczki V, Chen B, Redis R, Fabris L, Zhang X, Ivan C, Shimizu M, Rodriguez-Aguayo C, Dragomir M, Van Roosbroeck K, Almeida MI, Ciccone M, Nedelcu D, Cortez MA, Manshouri T, Calin S, Muftuoglu M, Banerjee PP, Badiwi MH, Parker-Thornburg J, Multani A, Welsh JW, Estecio MR, Ling H, Tomuleasa C, Dima D, Yang H, Alvarez H, You MJ, Radovich M, Shpall E, Fabbri M, Rezvani K, Girnita L, Berindan-Neagoe I, Maitra A, Verstovsek S, Fodde R, Bueso-Ramos C, Gagea M, Manero GG, Calin GA.

Genome Res. 2018 Apr;28(4):432-447. doi: 10.1101/gr.225128.117. Epub 2018 Mar 22.

PMID:
29567676
11.

Hematopoietic stem cells from induced pluripotent stem cells - considering the role of microRNA as a cell differentiation regulator.

Ferreira AF, Calin GA, Picanço-Castro V, Kashima S, Covas DT, de Castro FA.

J Cell Sci. 2018 Feb 21;131(4). pii: jcs203018. doi: 10.1242/jcs.203018. Review.

PMID:
29467236
12.

Crucial role of non-coding RNAs in disease.

Peng Y, Calin GA.

Cancer Lett. 2018 Apr 28;420:127-128. doi: 10.1016/j.canlet.2018.02.001. Epub 2018 Feb 6. No abstract available.

PMID:
29425682
13.

Featuring the special issue Guest Editor.

Calin GA.

Cancer Lett. 2018 Jun 1;423:27. doi: 10.1016/j.canlet.2018.01.004. Epub 2018 Jan 9. No abstract available.

PMID:
29330106
14.

MiR-181 family-specific behavior in different cancers: a meta-analysis view.

Pop-Bica C, Pintea S, Cojocneanu-Petric R, Del Sal G, Piazza S, Wu ZH, Alencar AJ, Lossos IS, Berindan-Neagoe I, Calin GA.

Cancer Metastasis Rev. 2018 Mar;37(1):17-32. doi: 10.1007/s10555-017-9714-9.

PMID:
29327093
15.

Publisher Correction: Transcribed ultraconserved region 339 promotes carcinogenesis by modulating tumor suppressor microRNAs.

Vannini I, Wise PM, Challagundla KB, Plousiou M, Raffini M, Bandini E, Fanini F, Paliaga G, Crawford M, Ferracin M, Ivan C, Fabris L, Davuluri RV, Guo Z, Cortez MA, Zhang X, Chen L, Zhang S, Fernandez-Cymering C, Han L, Carloni S, Salvi S, Ling H, Murtadha M, Neviani P, Gitlitz BJ, Laird-Offringa IA, Nana-Sinkam P, Negrini M, Liang H, Amadori D, Cimmino A, Calin GA, Fabbri M.

Nat Commun. 2018 Jan 8;9(1):160. doi: 10.1038/s41467-017-02485-1.

16.

Preface.

Calin GA, Van Roosbroeck K.

Cancer Metastasis Rev. 2018 Mar;37(1):3-4. doi: 10.1007/s10555-017-9722-9. No abstract available.

PMID:
29285656
17.

Transcribed ultraconserved region 339 promotes carcinogenesis by modulating tumor suppressor microRNAs.

Vannini I, Wise PM, Challagundla KB, Plousiou M, Raffini M, Bandini E, Fanini F, Paliaga G, Crawford M, Ferracin M, Ivan C, Fabris L, Davuluri RV, Guo Z, Cortez MA, Zhang X, Chen L, Zhang S, Fernandez-Cymering C, Han L, Carloni S, Salvi S, Ling H, Murtadha M, Neviani P, Gitlitz BJ, Laird-Offringa IA, Nana-Sinkam P, Negrini M, Liang H, Amadori D, Cimmino A, Calin GA, Fabbri M.

Nat Commun. 2017 Nov 27;8(1):1801. doi: 10.1038/s41467-017-01562-9. Erratum in: Nat Commun. 2018 Jan 8;9(1):160.

18.

miR-195 inhibits macrophages pro-inflammatory profile and impacts the crosstalk with smooth muscle cells.

Bras JP, Silva AM, Calin GA, Barbosa MA, Santos SG, Almeida MI.

PLoS One. 2017 Nov 22;12(11):e0188530. doi: 10.1371/journal.pone.0188530. eCollection 2017.

19.

Roles and clinical implications of microRNAs in acute lymphoblastic leukemia.

Ultimo S, Martelli AM, Zauli G, Vitale M, Calin GA, Neri LM.

J Cell Physiol. 2018 Aug;233(8):5642-5654. doi: 10.1002/jcp.26290. Epub 2018 Feb 28. Review.

PMID:
29154447
20.

A total transcriptome profiling method for plasma-derived extracellular vesicles: applications for liquid biopsies.

Amorim MG, Valieris R, Drummond RD, Pizzi MP, Freitas VM, Sinigaglia-Coimbra R, Calin GA, Pasqualini R, Arap W, Silva IT, Dias-Neto E, Nunes DN.

Sci Rep. 2017 Oct 31;7(1):14395. doi: 10.1038/s41598-017-14264-5.

21.

TRPA1-FGFR2 binding event is a regulatory oncogenic driver modulated by miRNA-142-3p.

Berrout J, Kyriakopoulou E, Moparthi L, Hogea AS, Berrout L, Ivan C, Lorger M, Boyle J, Peers C, Muench S, Gomez JE, Hu X, Hurst C, Hall T, Umamaheswaran S, Wesley L, Gagea M, Shires M, Manfield I, Knowles MA, Davies S, Suhling K, Gonzalez YT, Carragher N, Macleod K, Abbott NJ, Calin GA, Gamper N, Zygmunt PM, Timsah Z.

Nat Commun. 2017 Oct 16;8(1):947. doi: 10.1038/s41467-017-00983-w.

22.

Cell-to-cell communication: microRNAs as hormones.

Bayraktar R, Van Roosbroeck K, Calin GA.

Mol Oncol. 2017 Dec;11(12):1673-1686. doi: 10.1002/1878-0261.12144. Epub 2017 Oct 26. Review.

23.

To Wnt or Lose: The Missing Non-Coding Linc in Colorectal Cancer.

Shen P, Pichler M, Chen M, Calin GA, Ling H.

Int J Mol Sci. 2017 Sep 20;18(9). pii: E2003. doi: 10.3390/ijms18092003. Review.

24.

Serum HOTAIR and GAS5 levels as predictors of survival in patients with glioblastoma.

Shen J, Hodges TR, Song R, Gong Y, Calin GA, Heimberger AB, Zhao H.

Mol Carcinog. 2018 Jan;57(1):137-141. doi: 10.1002/mc.22739. Epub 2017 Oct 10.

PMID:
28926136
25.

The role of a new class of long noncoding RNAs transcribed from ultraconserved regions in cancer.

Terracciano D, Terreri S, de Nigris F, Costa V, Calin GA, Cimmino A.

Biochim Biophys Acta. 2017 Dec;1868(2):449-455. doi: 10.1016/j.bbcan.2017.09.001. Epub 2017 Sep 13. Review.

PMID:
28916343
26.

Association Between Germline Mutations in BRF1, a Subunit of the RNA Polymerase III Transcription Complex, and Hereditary Colorectal Cancer.

Bellido F, Sowada N, Mur P, Lázaro C, Pons T, Valdés-Mas R, Pineda M, Aiza G, Iglesias S, Soto JL, Urioste M, Caldés T, Balbín M, Blay P, Rueda D, Durán M, Valencia A, Moreno V, Brunet J, Blanco I, Navarro M, Calin GA, Borck G, Puente XS, Capellá G, Valle L.

Gastroenterology. 2018 Jan;154(1):181-194.e20. doi: 10.1053/j.gastro.2017.09.005. Epub 2017 Sep 12.

PMID:
28912018
27.

Regulation of hnRNPA1 by microRNAs controls the miR-18a-K-RAS axis in chemotherapy-resistant ovarian cancer.

Rodriguez-Aguayo C, Monroig PDC, Redis RS, Bayraktar E, Almeida MI, Ivan C, Fuentes-Mattei E, Rashed MH, Chavez-Reyes A, Ozpolat B, Mitra R, Sood AK, Calin GA, Lopez-Berestein G.

Cell Discov. 2017 Sep 12;3:17029. doi: 10.1038/celldisc.2017.29. eCollection 2017.

28.

Cancer Hallmarks and MicroRNAs: The Therapeutic Connection.

Van Roosbroeck K, Calin GA.

Adv Cancer Res. 2017;135:119-149. doi: 10.1016/bs.acr.2017.06.002. Epub 2017 Aug 12. Review.

PMID:
28882220
29.

Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587.

Figueroa J, Phillips LM, Shahar T, Hossain A, Gumin J, Kim H, Bean AJ, Calin GA, Fueyo J, Walters ET, Kalluri R, Verhaak RG, Lang FF.

Cancer Res. 2017 Nov 1;77(21):5808-5819. doi: 10.1158/0008-5472.CAN-16-2524. Epub 2017 Aug 30.

PMID:
28855213
30.

Circulating miRNAs in sepsis-A network under attack: An in-silico prediction of the potential existence of miRNA sponges in sepsis.

Vasilescu C, Dragomir M, Tanase M, Giza D, Purnichescu-Purtan R, Chen M, Yeung SJ, Calin GA.

PLoS One. 2017 Aug 18;12(8):e0183334. doi: 10.1371/journal.pone.0183334. eCollection 2017.

31.

The Many Faces of Long Noncoding RNAs in Cancer.

Wu X, Tudoran OM, Calin GA, Ivan M.

Antioxid Redox Signal. 2017 Oct 20. doi: 10.1089/ars.2017.7293. [Epub ahead of print]

PMID:
28793797
32.

Anti-leukemic activity of microRNA-26a in a chronic lymphocytic leukemia mouse model.

D'Abundo L, Callegari E, Bresin A, Chillemi A, Elamin BK, Guerriero P, Huang X, Saccenti E, Hussein EMAA, Casciano F, Secchiero P, Zauli G, Calin GA, Russo G, Lee LJ, Croce CM, Marcucci G, Sabbioni S, Malavasi F, Negrini M.

Oncogene. 2017 Nov 23;36(47):6617-6626. doi: 10.1038/onc.2017.269. Epub 2017 Aug 7.

33.

Understanding the Genomic Ultraconservations: T-UCRs and Cancer.

Fabris L, Calin GA.

Int Rev Cell Mol Biol. 2017;333:159-172. doi: 10.1016/bs.ircmb.2017.04.004. Epub 2017 Jun 7. Review.

PMID:
28729024
34.

Functional antagonism of β-arrestin isoforms balance IGF-1R expression and signalling with distinct cancer-related biological outcomes.

Suleymanova N, Crudden C, Shibano T, Worrall C, Oprea I, Tica A, Calin GA, Girnita A, Girnita L.

Oncogene. 2017 Oct 12;36(41):5734-5744. doi: 10.1038/onc.2017.179. Epub 2017 Jun 5.

35.

N-BLR, a primate-specific non-coding transcript leads to colorectal cancer invasion and migration.

Rigoutsos I, Lee SK, Nam SY, Anfossi S, Pasculli B, Pichler M, Jing Y, Rodriguez-Aguayo C, Telonis AG, Rossi S, Ivan C, Catela Ivkovic T, Fabris L, Clark PM, Ling H, Shimizu M, Redis RS, Shah MY, Zhang X, Okugawa Y, Jung EJ, Tsirigos A, Huang L, Ferdin J, Gafà R, Spizzo R, Nicoloso MS, Paranjape AN, Shariati M, Tiron A, Yeh JJ, Teruel-Montoya R, Xiao L, Melo SA, Menter D, Jiang ZQ, Flores ER, Negrini M, Goel A, Bar-Eli M, Mani SA, Liu CG, Lopez-Berestein G, Berindan-Neagoe I, Esteller M, Kopetz S, Lanza G, Calin GA.

Genome Biol. 2017 May 24;18(1):98. doi: 10.1186/s13059-017-1224-0.

36.

miR-196b-5p Regulates Colorectal Cancer Cell Migration and Metastases through Interaction with HOXB7 and GALNT5.

Stiegelbauer V, Vychytilova-Faltejskova P, Karbiener M, Pehserl AM, Reicher A, Resel M, Heitzer E, Ivan C, Bullock M, Ling H, Deutsch A, Wulf-Goldenberg A, Adiprasito JB, Stoeger H, Haybaeck J, Svoboda M, Stotz M, Hoefler G, Slaby O, Calin GA, Gerger A, Pichler M.

Clin Cancer Res. 2017 Sep 1;23(17):5255-5266. doi: 10.1158/1078-0432.CCR-17-0023. Epub 2017 May 22.

PMID:
28533224
37.

Dendritic Cell-derived Extracellular Vesicles mediate Mesenchymal Stem/Stromal Cell recruitment.

Silva AM, Almeida MI, Teixeira JH, Maia AF, Calin GA, Barbosa MA, Santos SG.

Sci Rep. 2017 May 10;7(1):1667. doi: 10.1038/s41598-017-01809-x.

38.

Plasma Viral miRNAs Indicate a High Prevalence of Occult Viral Infections.

Fuentes-Mattei E, Giza DE, Shimizu M, Ivan C, Manning JT, Tudor S, Ciccone M, Kargin OA, Zhang X, Mur P, do Amaral NS, Chen M, Tarrand JJ, Lupu F, Ferrajoli A, Keating MJ, Vasilescu C, Yeung SJ, Calin GA.

EBioMedicine. 2017 Jun;20:182-192. doi: 10.1016/j.ebiom.2017.04.018. Epub 2017 Apr 19.

39.

Exosomal miR-940 maintains SRC-mediated oncogenic activity in cancer cells: a possible role for exosomal disposal of tumor suppressor miRNAs.

Rashed MH, Kanlikilicer P, Rodriguez-Aguayo C, Pichler M, Bayraktar R, Bayraktar E, Ivan C, Filant J, Silva A, Aslan B, Denizli M, Mitra R, Ozpolat B, Calin GA, Sood AK, Abd-Ellah MF, Helal GK, Berestein GL.

Oncotarget. 2017 Mar 21;8(12):20145-20164. doi: 10.18632/oncotarget.15525.

40.

Regulation of PI3K signaling in T-cell acute lymphoblastic leukemia: a novel PTEN/Ikaros/miR-26b mechanism reveals a critical targetable role for PIK3CD.

Yuan T, Yang Y, Chen J, Li W, Li W, Zhang Q, Mi Y, Goswami RS, You JQ, Lin D, Qian MD, Calin S, Liang Y, Miranda RN, Calin GA, Zhou X, Ma L, Zweidler-McKay PA, Liu B, Weng AP, Medeiros LJ, Zhang Y, You MJ.

Leukemia. 2017 Nov;31(11):2355-2364. doi: 10.1038/leu.2017.80. Epub 2017 Mar 10.

41.

Current Insights into Long Non-Coding RNAs (LncRNAs) in Prostate Cancer.

Smolle MA, Bauernhofer T, Pummer K, Calin GA, Pichler M.

Int J Mol Sci. 2017 Feb 22;18(2). pii: E473. doi: 10.3390/ijms18020473. Review.

42.

HIF1A gene polymorphisms and human diseases: Graphical review of 97 association studies.

Gladek I, Ferdin J, Horvat S, Calin GA, Kunej T.

Genes Chromosomes Cancer. 2017 Jun;56(6):439-452. doi: 10.1002/gcc.22449. Epub 2017 Mar 31. Review.

43.

Noncoding RNAs and immune checkpoints-clinical implications as cancer therapeutics.

Smolle MA, Calin HN, Pichler M, Calin GA.

FEBS J. 2017 Jul;284(13):1952-1966. doi: 10.1111/febs.14030. Epub 2017 Feb 17. Review.

44.

Integrated MicroRNA-mRNA Profiling Identifies Oncostatin M as a Marker of Mesenchymal-Like ER-Negative/HER2-Negative Breast Cancer.

Bottai G, Diao L, Baggerly KA, Paladini L, Győrffy B, Raschioni C, Pusztai L, Calin GA, Santarpia L.

Int J Mol Sci. 2017 Jan 19;18(1). pii: E194. doi: 10.3390/ijms18010194.

45.

MALAT1 promoted invasiveness of gastric adenocarcinoma.

Lee NK, Lee JH, Ivan C, Ling H, Zhang X, Park CH, Calin GA, Lee SK.

BMC Cancer. 2017 Jan 11;17(1):46. doi: 10.1186/s12885-016-2988-4.

46.

SnapShot: Non-coding RNAs and Metabolism.

Redis RS, Calin GA.

Cell Metab. 2017 Jan 10;25(1):220-220.e1. doi: 10.1016/j.cmet.2016.12.012.

47.

From cell biology to immunology: Controlling metastatic progression of cancer via microRNA regulatory networks.

Park JH, Theodoratou E, Calin GA, Shin JI.

Oncoimmunology. 2016 Sep 9;5(11):e1230579. doi: 10.1080/2162402X.2016.1230579. eCollection 2016. Review.

48.

The emerging role of long noncoding RNAs in oral cancer.

Gomes CC, de Sousa SF, Calin GA, Gomez RS.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2017 Feb;123(2):235-241. doi: 10.1016/j.oooo.2016.10.006. Epub 2016 Oct 13. Review.

PMID:
27989708
49.

Non-coding RNAs: the cancer genome dark matter that matters!

Ling H, Girnita L, Buda O, Calin GA.

Clin Chem Lab Med. 2017 May 1;55(5):705-714. doi: 10.1515/cclm-2016-0740. Review.

50.

Combining Anti-Mir-155 with Chemotherapy for the Treatment of Lung Cancers.

Van Roosbroeck K, Fanini F, Setoyama T, Ivan C, Rodriguez-Aguayo C, Fuentes-Mattei E, Xiao L, Vannini I, Redis RS, D'Abundo L, Zhang X, Nicoloso MS, Rossi S, Gonzalez-Villasana V, Rupaimoole R, Ferracin M, Morabito F, Neri A, Ruvolo PP, Ruvolo VR, Pecot CV, Amadori D, Abruzzo L, Calin S, Wang X, You MJ, Ferrajoli A, Orlowski R, Plunkett W, Lichtenberg TM, Davuluri RV, Berindan-Neagoe I, Negrini M, Wistuba II, Kantarjian HM, Sood AK, Lopez-Berestein G, Keating MJ, Fabbri M, Calin GA.

Clin Cancer Res. 2017 Jun 1;23(11):2891-2904. doi: 10.1158/1078-0432.CCR-16-1025. Epub 2016 Nov 30.

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