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Items: 1 to 50 of 138

1.

The novel butyrate derivative phenylalanine-butyramide protects from doxorubicin-induced cardiotoxicity.

Russo M, Guida F, Paparo L, Trinchese G, Aitoro R, Avagliano C, Fiordelisi A, Napolitano F, Mercurio V, Sala V, Li M, Sorriento D, Ciccarelli M, Ghigo A, Hirsch E, Bianco R, Iaccarino G, Abete P, Bonaduce D, Calignano A, Berni Canani R, Tocchetti CG.

Eur J Heart Fail. 2019 Apr;21(4):519-528. doi: 10.1002/ejhf.1439. Epub 2019 Mar 6.

PMID:
30843309
2.

Neutralization of IL-17 rescues amyloid-β-induced neuroinflammation and memory impairment.

Cristiano C, Volpicelli F, Lippiello P, Buono B, Raucci F, Piccolo M, Iqbal AJ, Irace C, Miniaci MC, Perrone Capano C, Calignano A, Mascolo N, Maione F.

Br J Pharmacol. 2019 Jan 23. doi: 10.1111/bph.14586. [Epub ahead of print]

PMID:
30673121
3.

Fishing for Targets of Alien Metabolites: A Novel Peroxisome Proliferator-Activated Receptor (PPAR) Agonist from a Marine Pest.

Vitale RM, D'Aniello E, Gorbi S, Martella A, Silvestri C, Giuliani ME, Fellous T, Gentile A, Carbone M, Cutignano A, Grauso L, Magliozzi L, Polese G, D'Aniello B, Defranoux F, Felline S, Terlizzi A, Calignano A, Regoli F, Di Marzo V, Amodeo P, Mollo E.

Mar Drugs. 2018 Nov 3;16(11). pii: E431. doi: 10.3390/md16110431.

4.

Ultra-micronized palmitoylethanolamide rescues the cognitive decline-associated loss of neural plasticity in the neuropathic mouse entorhinal cortex-dentate gyrus pathway.

Boccella S, Cristiano C, Romano R, Iannotta M, Belardo C, Farina A, Guida F, Piscitelli F, Palazzo E, Mazzitelli M, Imperatore R, Tunisi L, de Novellis V, Cristino L, Di Marzo V, Calignano A, Maione S, Luongo L.

Neurobiol Dis. 2019 Jan;121:106-119. doi: 10.1016/j.nbd.2018.09.023. Epub 2018 Sep 25.

PMID:
30266286
5.

Palmitoylethanolamide counteracts autistic-like behaviours in BTBR T+tf/J mice: Contribution of central and peripheral mechanisms.

Cristiano C, Pirozzi C, Coretti L, Cavaliere G, Lama A, Russo R, Lembo F, Mollica MP, Meli R, Calignano A, Mattace Raso G.

Brain Behav Immun. 2018 Nov;74:166-175. doi: 10.1016/j.bbi.2018.09.003. Epub 2018 Sep 5.

6.

Gut microbiota composition and butyrate production in children affected by non-IgE-mediated cow's milk allergy.

Berni Canani R, De Filippis F, Nocerino R, Paparo L, Di Scala C, Cosenza L, Della Gatta G, Calignano A, De Caro C, Laiola M, Gilbert JA, Ercolini D.

Sci Rep. 2018 Aug 21;8(1):12500. doi: 10.1038/s41598-018-30428-3.

7.

Motor coordination and synaptic plasticity deficits are associated with increased cerebellar activity of NADPH oxidase, CAMKII, and PKC at preplaque stage in the TgCRND8 mouse model of Alzheimer's disease.

Russo R, Cattaneo F, Lippiello P, Cristiano C, Zurlo F, Castaldo M, Irace C, Borsello T, Santamaria R, Ammendola R, Calignano A, Miniaci MC.

Neurobiol Aging. 2018 Aug;68:123-133. doi: 10.1016/j.neurobiolaging.2018.02.025. Epub 2018 Mar 5.

PMID:
29602494
8.

Histamine-deficient mice do not respond to the antidepressant-like effects of oleoylethanolamide.

Costa A, Cristiano C, Cassano T, Gallelli CA, Gaetani S, Ghelardini C, Blandina P, Calignano A, Passani MB, Provensi G.

Neuropharmacology. 2018 Jun;135:234-241. doi: 10.1016/j.neuropharm.2018.03.033. Epub 2018 Mar 26.

PMID:
29596898
9.

Interplay Between Peripheral and Central Inflammation in Autism Spectrum Disorders: Possible Nutritional and Therapeutic Strategies.

Cristiano C, Lama A, Lembo F, Mollica MP, Calignano A, Mattace Raso G.

Front Physiol. 2018 Mar 7;9:184. doi: 10.3389/fphys.2018.00184. eCollection 2018. Review.

10.

Improving in vivo conversion of oleuropein into hydroxytyrosol by oral granules containing probiotic Lactobacillus plantarum 299v and an Olea europaea standardized extract.

Aponte M, Ungaro F, d'Angelo I, De Caro C, Russo R, Blaiotta G, Dal Piaz F, Calignano A, Miro A.

Int J Pharm. 2018 May 30;543(1-2):73-82. doi: 10.1016/j.ijpharm.2018.03.013. Epub 2018 Mar 8.

PMID:
29526619
11.

Antinociceptive effect of two novel transient receptor potential melastatin 8 antagonists in acute and chronic pain models in rat.

De Caro C, Russo R, Avagliano C, Cristiano C, Calignano A, Aramini A, Bianchini G, Allegretti M, Brandolini L.

Br J Pharmacol. 2018 May;175(10):1691-1706. doi: 10.1111/bph.14177. Epub 2018 Apr 14.

12.

Human Milk and Donkey Milk, Compared to Cow Milk, Reduce Inflammatory Mediators and Modulate Glucose and Lipid Metabolism, Acting on Mitochondrial Function and Oleylethanolamide Levels in Rat Skeletal Muscle.

Trinchese G, Cavaliere G, De Filippo C, Aceto S, Prisco M, Chun JT, Penna E, Negri R, Muredda L, Demurtas A, Banni S, Berni-Canani R, Mattace Raso G, Calignano A, Meli R, Greco L, Crispino M, Mollica MP.

Front Physiol. 2018 Jan 30;9:32. doi: 10.3389/fphys.2018.00032. eCollection 2018.

13.

The safety assessment of herbals with a new and ethical approach.

Aiello E, Russo R, Cristiano C, Calignano A.

Nat Prod Res. 2018 Aug;32(15):1838-1848. doi: 10.1080/14786419.2017.1402316. Epub 2017 Nov 28. Review.

PMID:
29179566
14.

Ketogal: A Derivative Ketorolac Molecule with Minor Ulcerogenic and Renal Toxicity.

Russo R, De Caro C, Avallone B, Magliocca S, Nieddu M, Boatto G, Troiano R, Cuomo R, Cirillo C, Avagliano C, Cristiano C, La Rana G, Sarnelli G, Calignano A, Rimoli MG.

Front Pharmacol. 2017 Nov 6;8:757. doi: 10.3389/fphar.2017.00757. eCollection 2017.

15.

Down regulation of pro-inflammatory pathways by tanshinone IIA and cryptotanshinone in a non-genetic mouse model of Alzheimer's disease.

Maione F, Piccolo M, De Vita S, Chini MG, Cristiano C, De Caro C, Lippiello P, Miniaci MC, Santamaria R, Irace C, De Feo V, Calignano A, Mascolo N, Bifulco G.

Pharmacol Res. 2018 Mar;129:482-490. doi: 10.1016/j.phrs.2017.11.018. Epub 2017 Nov 20.

PMID:
29158049
16.

Butyrate modulating effects on pro-inflammatory pathways in human intestinal epithelial cells.

Elce A, Amato F, Zarrilli F, Calignano A, Troncone R, Castaldo G, Canani RB.

Benef Microbes. 2017 Oct 13;8(5):841-847. doi: 10.3920/BM2016.0197. Epub 2017 Aug 31.

PMID:
28856908
17.

The potential role of cannabinoids in epilepsy treatment.

De Caro C, Leo A, Citraro R, De Sarro C, Russo R, Calignano A, Russo E.

Expert Rev Neurother. 2017 Nov;17(11):1069-1079. doi: 10.1080/14737175.2017.1373019. Epub 2017 Sep 4. Review.

PMID:
28845714
18.

Specific Signatures of the Gut Microbiota and Increased Levels of Butyrate in Children Treated with Fermented Cow's Milk Containing Heat-Killed Lactobacillus paracasei CBA L74.

Berni Canani R, De Filippis F, Nocerino R, Laiola M, Paparo L, Calignano A, De Caro C, Coretti L, Chiariotti L, Gilbert JA, Ercolini D.

Appl Environ Microbiol. 2017 Sep 15;83(19). pii: e01206-17. doi: 10.1128/AEM.01206-17. Print 2017 Oct 1.

19.

Sex-related alterations of gut microbiota composition in the BTBR mouse model of autism spectrum disorder.

Coretti L, Cristiano C, Florio E, Scala G, Lama A, Keller S, Cuomo M, Russo R, Pero R, Paciello O, Mattace Raso G, Meli R, Cocozza S, Calignano A, Chiariotti L, Lembo F.

Sci Rep. 2017 Mar 28;7:45356. doi: 10.1038/srep45356.

20.

Butyrate Regulates Liver Mitochondrial Function, Efficiency, and Dynamics in Insulin-Resistant Obese Mice.

Mollica MP, Mattace Raso G, Cavaliere G, Trinchese G, De Filippo C, Aceto S, Prisco M, Pirozzi C, Di Guida F, Lama A, Crispino M, Tronino D, Di Vaio P, Berni Canani R, Calignano A, Meli R.

Diabetes. 2017 May;66(5):1405-1418. doi: 10.2337/db16-0924. Epub 2017 Feb 21.

21.

Gut-brain Axis: Role of Lipids in the Regulation of Inflammation, Pain and CNS Diseases.

Russo R, Cristiano C, Avagliano C, De Caro C, La Rana G, Raso GM, Canani RB, Meli R, Calignano A.

Curr Med Chem. 2018;25(32):3930-3952. doi: 10.2174/0929867324666170216113756. Review.

PMID:
28215162
22.

Extracorporeal shock waves alone or combined with raloxifene promote bone formation and suppress resorption in ovariectomized rats.

Lama A, Santoro A, Corrado B, Pirozzi C, Paciello O, Pagano TB, Russo S, Calignano A, Mattace Raso G, Meli R.

PLoS One. 2017 Feb 3;12(2):e0171276. doi: 10.1371/journal.pone.0171276. eCollection 2017.

23.

Extensively hydrolyzed casein formula alone or with L. rhamnosus GG reduces β-lactoglobulin sensitization in mice.

Aitoro R, Simeoli R, Amoroso A, Paparo L, Nocerino R, Pirozzi C, di Costanzo M, Meli R, De Caro C, Picariello G, Mamone G, Calignano A, Nagler CR, Berni Canani R.

Pediatr Allergy Immunol. 2017 May;28(3):230-237. doi: 10.1111/pai.12687. Epub 2017 Jan 24.

PMID:
27992668
24.

Response to comment by Juan Segura-Aguilar: New preclinical model are required to discover neuroprotective compound in Parkinson's disease.

Mattace Raso G, Avagliano C, Calignano A.

Pharmacol Res. 2017 May;119:491-492. doi: 10.1016/j.phrs.2016.11.026. Epub 2016 Nov 24. No abstract available.

PMID:
27890814
25.

An orally administered butyrate-releasing derivative reduces neutrophil recruitment and inflammation in dextran sulphate sodium-induced murine colitis.

Simeoli R, Mattace Raso G, Pirozzi C, Lama A, Santoro A, Russo R, Montero-Melendez T, Berni Canani R, Calignano A, Perretti M, Meli R.

Br J Pharmacol. 2017 Jun;174(11):1484-1496. doi: 10.1111/bph.13637. Epub 2016 Nov 3.

26.

Polyphenol-rich virgin olive oil reduces insulin resistance and liver inflammation and improves mitochondrial dysfunction in high-fat diet fed rats.

Lama A, Pirozzi C, Mollica MP, Trinchese G, Di Guida F, Cavaliere G, Calignano A, Mattace Raso G, Berni Canani R, Meli R.

Mol Nutr Food Res. 2017 Mar;61(3). doi: 10.1002/mnfr.201600418. Epub 2016 Dec 20.

PMID:
27794174
27.

Pharmacokinetic-pharmacodynamic influence of N-palmitoylethanolamine, arachidonyl-2'-chloroethylamide and WIN 55,212-2 on the anticonvulsant activity of antiepileptic drugs against audiogenic seizures in DBA/2 mice.

Citraro R, Russo E, Leo A, Russo R, Avagliano C, Navarra M, Calignano A, De Sarro G.

Eur J Pharmacol. 2016 Nov 15;791:523-534. doi: 10.1016/j.ejphar.2016.09.029. Epub 2016 Sep 20.

PMID:
27663280
28.

Palmitoylethanolamide protects mice against 6-OHDA-induced neurotoxicity and endoplasmic reticulum stress: In vivo and in vitro evidence.

Avagliano C, Russo R, De Caro C, Cristiano C, La Rana G, Piegari G, Paciello O, Citraro R, Russo E, De Sarro G, Meli R, Mattace Raso G, Calignano A.

Pharmacol Res. 2016 Nov;113(Pt A):276-289. doi: 10.1016/j.phrs.2016.09.004. Epub 2016 Sep 8.

PMID:
27616549
29.

TSPO-ligands prevent oxidative damage and inflammatory response in C6 glioma cells by neurosteroid synthesis.

Santoro A, Mattace Raso G, Taliani S, Da Pozzo E, Simorini F, Costa B, Martini C, Laneri S, Sacchi A, Cosimelli B, Calignano A, Da Settimo F, Meli R.

Eur J Pharm Sci. 2016 Jun 10;88:124-31. doi: 10.1016/j.ejps.2016.04.006. Epub 2016 Apr 14.

PMID:
27094781
30.

Hydroxytyrosol prevents metabolic impairment reducing hepatic inflammation and restoring duodenal integrity in a rat model of NAFLD.

Pirozzi C, Lama A, Simeoli R, Paciello O, Pagano TB, Mollica MP, Di Guida F, Russo R, Magliocca S, Canani RB, Raso GM, Calignano A, Meli R.

J Nutr Biochem. 2016 Apr;30:108-15. doi: 10.1016/j.jnutbio.2015.12.004. Epub 2016 Jan 4.

PMID:
27012627
31.

Assessment of neuroactive steroids in cerebrospinal fluid comparing acute relapse and stable disease in relapsing-remitting multiple sclerosis.

Orefice N, Carotenuto A, Mangone G, Bues B, Rehm R, Cerillo I, Saccà F, Calignano A, Orefice G.

J Steroid Biochem Mol Biol. 2016 May;159:1-7. doi: 10.1016/j.jsbmb.2016.02.012. Epub 2016 Feb 15.

PMID:
26892094
32.

Nanoparticles prolong N-palmitoylethanolamide anti-inflammatory and analgesic effects in vivo.

Tronino D, Offerta A, Ostacolo C, Russo R, De Caro C, Calignano A, Puglia C, Blasi P.

Colloids Surf B Biointerfaces. 2016 May 1;141:311-317. doi: 10.1016/j.colsurfb.2016.01.058. Epub 2016 Feb 1.

PMID:
26866893
33.

Oral Palmitoylethanolamide Treatment Is Associated with Reduced Cutaneous Adverse Effects of Interferon-β1a and Circulating Proinflammatory Cytokines in Relapsing-Remitting Multiple Sclerosis.

Orefice NS, Alhouayek M, Carotenuto A, Montella S, Barbato F, Comelli A, Calignano A, Muccioli GG, Orefice G.

Neurotherapeutics. 2016 Apr;13(2):428-38. doi: 10.1007/s13311-016-0420-z.

34.

When Nutraceuticals Reinforce Drugs Side Effects: A Case Report.

Russo R, Gallelli L, Cannataro R, Perri M, Calignano A, Citraro R, Russo E, Gareri P, Corsonello A, Sarro GD.

Curr Drug Saf. 2016;11(3):264-6.

PMID:
26830519
35.

Sodium butyrate and its synthetic amide derivative modulate nociceptive behaviors in mice.

Russo R, De Caro C, Avagliano C, Cristiano C, La Rana G, Mattace Raso G, Berni Canani R, Meli R, Calignano A.

Pharmacol Res. 2016 Jan;103:279-91. doi: 10.1016/j.phrs.2015.11.026. Epub 2015 Dec 8.

PMID:
26675718
36.

Lactobacillus rhamnosus GG-supplemented formula expands butyrate-producing bacterial strains in food allergic infants.

Berni Canani R, Sangwan N, Stefka AT, Nocerino R, Paparo L, Aitoro R, Calignano A, Khan AA, Gilbert JA, Nagler CR.

ISME J. 2016 Mar;10(3):742-50. doi: 10.1038/ismej.2015.151. Epub 2015 Sep 22.

37.

Improvement of Topical Palmitoylethanolamide Anti-Inflammatory Activity by Pegylated Prodrugs.

Tronino D, Russo R, Ostacolo C, Mazzolari A, De Caro C, Avagliano C, Laneri S, La Rana G, Sacchi A, Della Valle F, Vistoli G, Calignano A.

Mol Pharm. 2015 Sep 8;12(9):3369-79. doi: 10.1021/acs.molpharmaceut.5b00397. Epub 2015 Aug 24.

PMID:
26289562
38.

Alginate-hyaluronan composite hydrogels accelerate wound healing process.

Catanzano O, D'Esposito V, Acierno S, Ambrosio MR, De Caro C, Avagliano C, Russo P, Russo R, Miro A, Ungaro F, Calignano A, Formisano P, Quaglia F.

Carbohydr Polym. 2015 Oct 20;131:407-14. doi: 10.1016/j.carbpol.2015.05.081. Epub 2015 Jun 16.

PMID:
26256201
39.

Peroxisome proliferator-activated receptor alpha plays a crucial role in behavioral repetition and cognitive flexibility in mice.

D'Agostino G, Cristiano C, Lyons DJ, Citraro R, Russo E, Avagliano C, Russo R, Raso GM, Meli R, De Sarro G, Heisler LK, Calignano A.

Mol Metab. 2015 May 2;4(7):528-36. doi: 10.1016/j.molmet.2015.04.005. eCollection 2015 Jul.

40.

Antineuropathic profile of N-palmitoylethanolamine in a rat model of oxaliplatin-induced neurotoxicity.

Di Cesare Mannelli L, Pacini A, Corti F, Boccella S, Luongo L, Esposito E, Cuzzocrea S, Maione S, Calignano A, Ghelardini C.

PLoS One. 2015 Jun 3;10(6):e0128080. doi: 10.1371/journal.pone.0128080. eCollection 2015.

41.

Palmitoylethanolamide treatment reduces blood pressure in spontaneously hypertensive rats: involvement of cytochrome p450-derived eicosanoids and renin angiotensin system.

Mattace Raso G, Pirozzi C, d'Emmanuele di Villa Bianca R, Simeoli R, Santoro A, Lama A, Di Guida F, Russo R, De Caro C, Sorrentino R, Calignano A, Meli R.

PLoS One. 2015 May 7;10(5):e0123602. doi: 10.1371/journal.pone.0123602. eCollection 2015.

42.

Preventive and therapeutic effects of Lactobacillus paracasei B21060-based synbiotic treatment on gut inflammation and barrier integrity in colitic mice.

Simeoli R, Mattace Raso G, Lama A, Pirozzi C, Santoro A, Di Guida F, Sanges M, Aksoy E, Calignano A, D'Arienzo A, Meli R.

J Nutr. 2015 Jun;145(6):1202-10. doi: 10.3945/jn.114.205989. Epub 2015 Apr 29.

PMID:
25926411
43.

Melt-spun bioactive sutures containing nanohybrids for local delivery of anti-inflammatory drugs.

Catanzano O, Acierno S, Russo P, Cervasio M, Del Basso De Caro M, Bolognese A, Sammartino G, Califano L, Marenzi G, Calignano A, Acierno D, Quaglia F.

Mater Sci Eng C Mater Biol Appl. 2014 Oct;43:300-9. doi: 10.1016/j.msec.2014.07.012. Epub 2014 Jul 10.

PMID:
25175217
44.

Galactosyl prodrug of palmitoylethanolamide: synthesis, stability, cell permeation and cytoprotective activity.

Luongo E, Russo R, Avagliano C, Santoro A, Melisi D, Orefice NS, Raso GM, Meli R, Magliocca S, Nieddu M, Santiago GM, Boatto G, Calignano A, Rimoli MG.

Eur J Pharm Sci. 2014 Oct 1;62:33-9. doi: 10.1016/j.ejps.2014.05.009. Epub 2014 May 19.

PMID:
24854456
45.

Palmitoylethanolamide in CNS health and disease.

Mattace Raso G, Russo R, Calignano A, Meli R.

Pharmacol Res. 2014 Aug;86:32-41. doi: 10.1016/j.phrs.2014.05.006. Epub 2014 May 17. Review.

PMID:
24844438
46.

Role of innate immune response in non-alcoholic Fatty liver disease: metabolic complications and therapeutic tools.

Meli R, Mattace Raso G, Calignano A.

Front Immunol. 2014 Apr 23;5:177. doi: 10.3389/fimmu.2014.00177. eCollection 2014. Review.

47.

Palmitoylethanolamide prevents metabolic alterations and restores leptin sensitivity in ovariectomized rats.

Mattace Raso G, Santoro A, Russo R, Simeoli R, Paciello O, Di Carlo C, Diano S, Calignano A, Meli R.

Endocrinology. 2014 Apr;155(4):1291-301. doi: 10.1210/en.2013-1823. Epub 2014 Jan 15.

48.

Genotype-dependency of butyrate efficacy in children with congenital chloride diarrhea.

Canani RB, Terrin G, Elce A, Pezzella V, Heinz-Erian P, Pedrolli A, Centenari C, Amato F, Tomaiuolo R, Calignano A, Troncone R, Castaldo G.

Orphanet J Rare Dis. 2013 Dec 19;8:194. doi: 10.1186/1750-1172-8-194.

49.

Effects of a Lactobacillus paracasei B21060 based synbiotic on steatosis, insulin signaling and toll-like receptor expression in rats fed a high-fat diet.

Raso GM, Simeoli R, Iacono A, Santoro A, Amero P, Paciello O, Russo R, D'Agostino G, Di Costanzo M, Canani RB, Calignano A, Meli R.

J Nutr Biochem. 2014 Jan;25(1):81-90. doi: 10.1016/j.jnutbio.2013.09.006. Epub 2013 Oct 10.

PMID:
24314869
50.

Isoxazole derivatives as potent transient receptor potential melastatin type 8 (TRPM8) agonists.

Ostacolo C, Ambrosino P, Russo R, Lo Monte M, Soldovieri MV, Laneri S, Sacchi A, Vistoli G, Taglialatela M, Calignano A.

Eur J Med Chem. 2013 Nov;69:659-69. doi: 10.1016/j.ejmech.2013.08.056. Epub 2013 Sep 20.

PMID:
24095758

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