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Items: 1 to 50 of 57

1.

CXCR7 contributes to the aggressive phenotype of cholangiocarcinoma cells.

Gentilini A, Caligiuri A, Raggi C, Rombouts K, Pinzani M, Lori G, Correnti M, Invernizzi P, Rovida E, Navari N, Di Matteo S, Alvaro D, Banales JM, Rodrigues P, Raschioni C, Donadon M, Di Tommaso L, Marra F.

Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865(9):2246-2256. doi: 10.1016/j.bbadis.2019.04.020. Epub 2019 May 3.

PMID:
31059778
2.

Myostatin regulates the fibrogenic phenotype of hepatic stellate cells via c-jun N-terminal kinase activation.

Delogu W, Caligiuri A, Provenzano A, Rosso C, Bugianesi E, Coratti A, Macias-Barragan J, Galastri S, Di Maira G, Marra F.

Dig Liver Dis. 2019 Apr 17. pii: S1590-8658(19)30113-6. doi: 10.1016/j.dld.2019.03.002. [Epub ahead of print]

PMID:
31005555
3.

The PNPLA3 I148M variant modulates the fibrogenic phenotype of human hepatic stellate cells.

Bruschi FV, Claudel T, Tardelli M, Caligiuri A, Stulnig TM, Marra F, Trauner M.

Hepatology. 2017 Jun;65(6):1875-1890. doi: 10.1002/hep.29041. Epub 2017 Apr 18.

PMID:
28073161
4.

Hepatic stellate cells induce hepatocellular carcinoma cell resistance to sorafenib through the laminin-332/α3 integrin axis recovery of focal adhesion kinase ubiquitination.

Azzariti A, Mancarella S, Porcelli L, Quatrale AE, Caligiuri A, Lupo L, Dituri F, Giannelli G.

Hepatology. 2016 Dec;64(6):2103-2117. doi: 10.1002/hep.28835. Epub 2016 Oct 27.

PMID:
27639064
5.

Novel Aspects in the Pathogenesis of Nonalcoholic Steatohepatitis.

Gentilini A, Caligiuri A, Provenzano A, Marra F.

Curr Mol Med. 2016;16(8):710-720. Review.

PMID:
27774883
6.

Molecular Pathogenesis of NASH.

Caligiuri A, Gentilini A, Marra F.

Int J Mol Sci. 2016 Sep 20;17(9). pii: E1575. Review.

7.

[Effects of alpha lipoic acid and pirfenidone on liver cells antioxidant modulation against oxidative damage].

Macias-Barragan J, Caligiuri A, García-Banuelos J, Parola M, Pinzani M, Armendariz-Borunda J.

Rev Med Chil. 2014 Dec;142(12):1553-64. doi: 10.4067/S0034-98872014001200009. Spanish.

8.

Allergic reaction or food poisoning? The history holds the clue.

Nowak C, Caligiuri A.

JAAPA. 2012 Sep;25(9):31-3. No abstract available.

PMID:
22991884
9.

Role of the stromal-derived factor-1 (SDF-1)-CXCR4 axis in the interaction between hepatic stellate cells and cholangiocarcinoma.

Gentilini A, Rombouts K, Galastri S, Caligiuri A, Mingarelli E, Mello T, Marra F, Mantero S, Roncalli M, Invernizzi P, Pinzani M.

J Hepatol. 2012 Oct;57(4):813-20. doi: 10.1016/j.jhep.2012.06.012. Epub 2012 Jun 19.

PMID:
22727731
10.

MARCKS actin-binding capacity mediates actin filament assembly during mitosis in human hepatic stellate cells.

Rombouts K, Mello T, Liotta F, Galli A, Caligiuri A, Annunziato F, Pinzani M.

Am J Physiol Cell Physiol. 2012 Aug 15;303(4):C357-67. doi: 10.1152/ajpcell.00093.2012. Epub 2012 May 2.

11.

Lack of CC chemokine ligand 2 differentially affects inflammation and fibrosis according to the genetic background in a murine model of steatohepatitis.

Galastri S, Zamara E, Milani S, Novo E, Provenzano A, Delogu W, Vizzutti F, Sutti S, Locatelli I, Navari N, Vivoli E, Caligiuri A, Pinzani M, Albano E, Parola M, Marra F.

Clin Sci (Lond). 2012 Oct;123(7):459-71. doi: 10.1042/CS20110515.

12.

Aryltriflates as a Neglected Moiety in Medicinal Chemistry: A Case Study from a Lead Optimization of CXCL8 Inhibitors.

Moriconi A, Bigogno C, Bianchini G, Caligiuri A, Resconi A, Dondio MG, D'Anniballe G, Allegretti M.

ACS Med Chem Lett. 2011 Aug 7;2(10):768-73. doi: 10.1021/ml2001533. eCollection 2011 Oct 13.

13.

Hepatic stellate cells stimulate HCC cell migration via laminin-5 production.

Santamato A, Fransvea E, Dituri F, Caligiuri A, Quaranta M, Niimi T, Pinzani M, Antonaci S, Giannelli G.

Clin Sci (Lond). 2011 Aug;121(4):159-68. doi: 10.1042/CS20110002.

PMID:
21413933
14.

Intracellular reactive oxygen species are required for directional migration of resident and bone marrow-derived hepatic pro-fibrogenic cells.

Novo E, Busletta C, Bonzo LV, Povero D, Paternostro C, Mareschi K, Ferrero I, David E, Bertolani C, Caligiuri A, Cannito S, Tamagno E, Compagnone A, Colombatto S, Marra F, Fagioli F, Pinzani M, Parola M.

J Hepatol. 2011 May;54(5):964-74. doi: 10.1016/j.jhep.2010.09.022. Epub 2010 Oct 31.

15.

Farnesoid X receptor critically determines the fibrotic response in mice but is expressed to a low extent in human hepatic stellate cells and periductal myofibroblasts.

Fickert P, Fuchsbichler A, Moustafa T, Wagner M, Zollner G, Halilbasic E, Stöger U, Arrese M, Pizarro M, Solís N, Carrasco G, Caligiuri A, Sombetzki M, Reisinger E, Tsybrovskyy O, Zatloukal K, Denk H, Jaeschke H, Pinzani M, Trauner M.

Am J Pathol. 2009 Dec;175(6):2392-405. doi: 10.2353/ajpath.2009.090114. Epub 2009 Nov 12. Erratum in: Am J Pathol. 2010 May;176(5):2581.

16.

Curcumin limits the fibrogenic evolution of experimental steatohepatitis.

Vizzutti F, Provenzano A, Galastri S, Milani S, Delogu W, Novo E, Caligiuri A, Zamara E, Arena U, Laffi G, Parola M, Pinzani M, Marra F.

Lab Invest. 2010 Jan;90(1):104-15. doi: 10.1038/labinvest.2009.112. Epub 2009 Nov 9.

17.

gp120 modulates the biology of human hepatic stellate cells: a link between HIV infection and liver fibrogenesis.

Bruno R, Galastri S, Sacchi P, Cima S, Caligiuri A, DeFranco R, Milani S, Gessani S, Fantuzzi L, Liotta F, Frosali F, Antonucci G, Pinzani M, Marra F.

Gut. 2010 Apr;59(4):513-20. doi: 10.1136/gut.2008.163287. Epub 2009 Sep 7.

PMID:
19736361
18.

Silybin, a component of sylimarin, exerts anti-inflammatory and anti-fibrogenic effects on human hepatic stellate cells.

Trappoliere M, Caligiuri A, Schmid M, Bertolani C, Failli P, Vizzutti F, Novo E, di Manzano C, Marra F, Loguercio C, Pinzani M.

J Hepatol. 2009 Jun;50(6):1102-11. doi: 10.1016/j.jhep.2009.02.023. Epub 2009 Apr 5.

PMID:
19398228
19.

Evaluation of intracellular signalling pathways in response to insulin-like growth factor I in apoptotic-resistant activated human hepatic stellate cells.

Gentilini A, Lottini B, Brogi M, Caligiuri A, Cosmi L, Marra F, Pinzani M.

Fibrogenesis Tissue Repair. 2009 Jan 30;2(1):1. doi: 10.1186/1755-1536-2-1.

20.

MARCKS is a downstream effector in platelet-derived growth factor-induced cell motility in activated human hepatic stellate cells.

Rombouts K, Lottini B, Caligiuri A, Liotta F, Mello T, Carloni V, Marra F, Pinzani M.

Exp Cell Res. 2008 Apr 15;314(7):1444-54. doi: 10.1016/j.yexcr.2008.01.029. Epub 2008 Feb 12.

PMID:
18329017
21.

Adenosine monophosphate-activated protein kinase modulates the activated phenotype of hepatic stellate cells.

Caligiuri A, Bertolani C, Guerra CT, Aleffi S, Galastri S, Trappoliere M, Vizzutti F, Gelmini S, Laffi G, Pinzani M, Marra F.

Hepatology. 2008 Feb;47(2):668-76.

PMID:
18098312
22.

ERK5 differentially regulates PDGF-induced proliferation and migration of hepatic stellate cells.

Rovida E, Navari N, Caligiuri A, Dello Sbarba P, Marra F.

J Hepatol. 2008 Jan;48(1):107-15. Epub 2007 Oct 17.

PMID:
17998143
23.

Proangiogenic cytokines as hypoxia-dependent factors stimulating migration of human hepatic stellate cells.

Novo E, Cannito S, Zamara E, Valfrè di Bonzo L, Caligiuri A, Cravanzola C, Compagnone A, Colombatto S, Marra F, Pinzani M, Parola M.

Am J Pathol. 2007 Jun;170(6):1942-53.

24.

Synthesis and pharmacological evaluation of novel conformationally constrained homologues of glutamic acid.

Conti P, Caligiuri A, Pinto A, Roda G, Tamborini L, Nielsen B, Madsen U, Frydenvang K, Colombo A, De Micheli C.

Eur J Med Chem. 2007 Aug;42(8):1059-68. Epub 2007 Jan 27.

PMID:
17346858
25.

Tin-mediated synthesis of lyso-phospholipids.

Fasoli E, Arnone A, Caligiuri A, D'Arrigo P, de Ferra L, Servi S.

Org Biomol Chem. 2006 Aug 7;4(15):2974-8. Epub 2006 Jul 4.

PMID:
16855747
26.

Dose dependent and divergent effects of superoxide anion on cell death, proliferation, and migration of activated human hepatic stellate cells.

Novo E, Marra F, Zamara E, Valfrè di Bonzo L, Caligiuri A, Cannito S, Antonaci C, Colombatto S, Pinzani M, Parola M.

Gut. 2006 Jan;55(1):90-7. Epub 2005 Jul 24.

27.

Parvovirus B-19 infection during pregnancy.

Al-Khan A, Caligiuri A, Apuzzio J.

Infect Dis Obstet Gynecol. 2003;11(3):175-9. Review.

28.

4-Hydroxynonenal as a selective pro-fibrogenic stimulus for activated human hepatic stellate cells.

Zamara E, Novo E, Marra F, Gentilini A, Romanelli RG, Caligiuri A, Robino G, Tamagno E, Aragno M, Danni O, Autelli R, Colombatto S, Dianzani MU, Pinzani M, Parola M.

J Hepatol. 2004 Jan;40(1):60-8.

PMID:
14672615
29.

Antifibrogenic effects of canrenone, an antialdosteronic drug, on human hepatic stellate cells.

Caligiuri A, De Franco RM, Romanelli RG, Gentilini A, Meucci M, Failli P, Mazzetti L, Rombouts K, Geerts A, Vanasia M, Gentilini P, Marra F, Pinzani M.

Gastroenterology. 2003 Feb;124(2):504-20.

PMID:
12557155
30.

Cell adhesion regulates platelet-derived growth factor-induced MAP kinase and PI-3 kinase activation in stellate cells.

Carloni V, Defranco RM, Caligiuri A, Gentilini A, Sciammetta SC, Baldi E, Lottini B, Gentilini P, Pinzani M.

Hepatology. 2002 Sep;36(3):582-91.

PMID:
12198650
31.

Up-regulated expression of fractalkine and its receptor CX3CR1 during liver injury in humans.

Efsen E, Grappone C, DeFranco RM, Milani S, Romanelli RG, Bonacchi A, Caligiuri A, Failli P, Annunziato F, Pagliai G, Pinzani M, Laffi G, Gentilini P, Marra F.

J Hepatol. 2002 Jul;37(1):39-47.

PMID:
12076860
32.

Interaction between 4-hydroxy-2,3-alkenals and the platelet-derived growth factor-beta receptor. Reduced tyrosine phosphorylation and downstream signaling in hepatic stellate cells.

Robino G, Parola M, Marra F, Caligiuri A, De Franco RM, Zamara E, Bellomo G, Gentilini P, Pinzani M, Dianzani MU.

J Biol Chem. 2000 Dec 22;275(51):40561-7.

33.

Nitrovasodilators inhibit platelet-derived growth factor-induced proliferation and migration of activated human hepatic stellate cells.

Failli P, DeFRANCO RM, Caligiuri A, Gentilini A, Romanelli RG, Marra F, Batignani G, Guerra CT, Laffi G, Gentilini P, Pinzani M.

Gastroenterology. 2000 Aug;119(2):479-92.

PMID:
10930383
34.

Ligands of peroxisome proliferator-activated receptor gamma modulate profibrogenic and proinflammatory actions in hepatic stellate cells.

Marra F, Efsen E, Romanelli RG, Caligiuri A, Pastacaldi S, Batignani G, Bonacchi A, Caporale R, Laffi G, Pinzani M, Gentilini P.

Gastroenterology. 2000 Aug;119(2):466-78.

PMID:
10930382
35.

Gastrin inhibits cholangiocyte growth in bile duct-ligated rats by interaction with cholecystokinin-B/Gastrin receptors via D-myo-inositol 1,4,5-triphosphate-, Ca(2+)-, and protein kinase C alpha-dependent mechanisms.

Glaser S, Benedetti A, Marucci L, Alvaro D, Baiocchi L, Kanno N, Caligiuri A, Phinizy JL, Chowdury U, Papa E, LeSage G, Alpini G.

Hepatology. 2000 Jul;32(1):17-25.

PMID:
10869284
36.

Extracellular signal-regulated kinase activation differentially regulates platelet-derived growth factor's actions in hepatic stellate cells, and is induced by in vivo liver injury in the rat.

Marra F, Arrighi MC, Fazi M, Caligiuri A, Pinzani M, Romanelli RG, Efsen E, Laffi G, Gentilini P.

Hepatology. 1999 Oct;30(4):951-8.

PMID:
10498647
37.

Expression of platelet-derived growth factor in newly formed cholangiocytes during experimental biliary fibrosis in rats.

Grappone C, Pinzani M, Parola M, Pellegrini G, Caligiuri A, DeFranco R, Marra F, Herbst H, Alpini G, Milani S.

J Hepatol. 1999 Jul;31(1):100-9.

PMID:
10424289
38.

Cholinergic system modulates growth, apoptosis, and secretion of cholangiocytes from bile duct-ligated rats.

LeSagE G, Alvaro D, Benedetti A, Glaser S, Marucci L, Baiocchi L, Eisel W, Caligiuri A, Phinizy JL, Rodgers R, Francis H, Alpini G.

Gastroenterology. 1999 Jul;117(1):191-9.

PMID:
10381927
39.

Acute carbon tetrachloride feeding induces damage of large but not small cholangiocytes from BDL rat liver.

LeSage GD, Glaser SS, Marucci L, Benedetti A, Phinizy JL, Rodgers R, Caligiuri A, Papa E, Tretjak Z, Jezequel AM, Holcomb LA, Alpini G.

Am J Physiol. 1999 May;276(5):G1289-301. doi: 10.1152/ajpgi.1999.276.5.G1289.

PMID:
10330021
40.

Acute carbon tetrachloride feeding selectively damages large, but not small, cholangiocytes from normal rat liver.

LeSage GD, Benedetti A, Glaser S, Marucci L, Tretjak Z, Caligiuri A, Rodgers R, Phinizy JL, Baiocchi L, Francis H, Lasater J, Ugili L, Alpini G.

Hepatology. 1999 Feb;29(2):307-19.

PMID:
9918904
41.

Bile acid feeding induces cholangiocyte proliferation and secretion: evidence for bile acid-regulated ductal secretion.

Alpini G, Glaser SS, Ueno Y, Rodgers R, Phinizy JL, Francis H, Baiocchi L, Holcomb LA, Caligiuri A, LeSage GD.

Gastroenterology. 1999 Jan;116(1):179-86.

PMID:
9869616
42.

Endothelin-1 inhibits secretin-stimulated ductal secretion by interacting with ETA receptors on large cholangiocytes.

Caligiuri A, Glaser S, Rodgers RE, Phinizy JL, Robertson W, Papa E, Pinzani M, Alpini G.

Am J Physiol. 1998 Oct;275(4):G835-46. doi: 10.1152/ajpgi.1998.275.4.G835.

PMID:
9756516
43.

Heterogeneity of the proliferative capacity of rat cholangiocytes after bile duct ligation.

Alpini G, Glaser SS, Ueno Y, Pham L, Podila PV, Caligiuri A, LeSage G, LaRusso NF.

Am J Physiol. 1998 Apr;274(4):G767-75. doi: 10.1152/ajpgi.1998.274.4.G767.

PMID:
9575860
44.

Gastrin inhibits secretin-induced ductal secretion by interaction with specific receptors on rat cholangiocytes.

Glaser SS, Rodgers RE, Phinizy JL, Robertson WE, Lasater J, Caligiuri A, Tretjak Z, LeSage GD, Alpini G.

Am J Physiol. 1997 Nov;273(5):G1061-70. doi: 10.1152/ajpgi.1997.273.5.G1061.

PMID:
9374703
45.

Effect of pentoxifylline on the degradation of procollagen type I produced by human hepatic stellate cells in response to transforming growth factor-beta 1.

Romanelli RG, Caligiuri A, Carloni V, DeFranco R, Montalto P, Ceni E, Casini A, Gentilini P, Pinzani M.

Br J Pharmacol. 1997 Nov;122(6):1047-54.

46.

Functional expression of the apical Na+-dependent bile acid transporter in large but not small rat cholangiocytes.

Alpini G, Glaser SS, Rodgers R, Phinizy JL, Robertson WE, Lasater J, Caligiuri A, Tretjak Z, LeSage GD.

Gastroenterology. 1997 Nov;113(5):1734-40.

PMID:
9352879
47.

Bile acids stimulate proliferative and secretory events in large but not small cholangiocytes.

Alpini G, Glaser S, Robertson W, Phinizy JL, Rodgers RE, Caligiuri A, LeSage G.

Am J Physiol. 1997 Aug;273(2 Pt 1):G518-29.

PMID:
9277433
48.

Neutrophil-derived superoxide anion induces lipid peroxidation and stimulates collagen synthesis in human hepatic stellate cells: role of nitric oxide.

Casini A, Ceni E, Salzano R, Biondi P, Parola M, Galli A, Foschi M, Caligiuri A, Pinzani M, Surrenti C.

Hepatology. 1997 Feb;25(2):361-7.

PMID:
9021948
49.

Inhibition by pentoxifylline of extracellular signal-regulated kinase activation by platelet-derived growth factor in hepatic stellate cells.

Pinzani M, Marra F, Caligiuri A, DeFranco R, Gentilini A, Failli P, Gentilini P.

Br J Pharmacol. 1996 Nov;119(6):1117-24.

50.

Induction of procollagen type I gene expression and synthesis in human hepatic stellate cells by 4-hydroxy-2,3-nonenal and other 4-hydroxy-2,3-alkenals is related to their molecular structure.

Parola M, Pinzani M, Casini A, Leonarduzzi G, Marra F, Caligiuri A, Ceni E, Biondi P, Poli G, Dianzani MU.

Biochem Biophys Res Commun. 1996 May 15;222(2):261-4.

PMID:
8670193

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