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Items: 38

1.

Evaluation of Luminogenic Substrates as Probe Substrates for Bacterial Cytochrome P450 Enzymes: Application to Mycobacterium tuberculosis.

Ortega Ugalde S, Ma D, Cali JJ, Commandeur JNM.

SLAS Discov. 2019 Aug;24(7):745-754. doi: 10.1177/2472555219853220. Epub 2019 Jun 17.

2.

A real-time, bioluminescent annexin V assay for the assessment of apoptosis.

Kupcho K, Shultz J, Hurst R, Hartnett J, Zhou W, Machleidt T, Grailer J, Worzella T, Riss T, Lazar D, Cali JJ, Niles A.

Apoptosis. 2019 Feb;24(1-2):184-197. doi: 10.1007/s10495-018-1502-7.

3.

Cell-based, bioluminescent assay for monitoring the interaction between PCSK9 and the LDL receptor.

Duellman SJ, Machleidt T, Cali JJ, Vidugiriene J.

J Lipid Res. 2017 Aug;58(8):1722-1729. doi: 10.1194/jlr.D074658. Epub 2017 Jun 13.

4.

Bioluminescent Assays for Glucose and Glutamine Metabolism: High-Throughput Screening for Changes in Extracellular and Intracellular Metabolites.

Leippe D, Sobol M, Vidugiris G, Cali JJ, Vidugiriene J.

SLAS Discov. 2017 Apr;22(4):366-377. doi: 10.1177/1087057116675612. Epub 2016 Nov 2.

PMID:
27803177
5.

A bioluminescent assay for measuring glucose uptake.

Valley MP, Karassina N, Aoyama N, Carlson C, Cali JJ, Vidugiriene J.

Anal Biochem. 2016 Jul 15;505:43-50. doi: 10.1016/j.ab.2016.04.010. Epub 2016 Apr 26.

PMID:
27130501
6.

Novel No-Wash Luminogenic Probes for the Detection of Transporter Uptake Activity.

Mustafa D, Ma D, Zhou W, Meisenheimer P, Cali JJ.

Bioconjug Chem. 2016 Jan 20;27(1):87-101. doi: 10.1021/acs.bioconjchem.5b00495. Epub 2016 Jan 11.

PMID:
26684581
7.

Bioluminescent, Nonlytic, Real-Time Cell Viability Assay and Use in Inhibitor Screening.

Duellman SJ, Zhou W, Meisenheimer P, Vidugiris G, Cali JJ, Gautam P, Wennerberg K, Vidugiriene J.

Assay Drug Dev Technol. 2015 Oct;13(8):456-65. doi: 10.1089/adt.2015.669. Epub 2015 Sep 18.

8.

Altered cytotoxicity of ROS-inducing compounds by sodium pyruvate in cell culture medium depends on the location of ROS generation.

Kelts JL, Cali JJ, Duellman SJ, Shultz J.

Springerplus. 2015 Jun 17;4:269. doi: 10.1186/s40064-015-1063-y. eCollection 2015.

9.

Bioluminescent cell-based NAD(P)/NAD(P)H assays for rapid dinucleotide measurement and inhibitor screening.

Vidugiriene J, Leippe D, Sobol M, Vidugiris G, Zhou W, Meisenheimer P, Gautam P, Wennerberg K, Cali JJ.

Assay Drug Dev Technol. 2014 Nov-Dec;12(9-10):514-26. doi: 10.1089/adt.2014.605.

10.

Validation of a HTS-amenable assay to detect drug-induced mitochondrial toxicity in the absence and presence of cell death.

Swiss R, Niles A, Cali JJ, Nadanaciva S, Will Y.

Toxicol In Vitro. 2013 Sep;27(6):1789-97. doi: 10.1016/j.tiv.2013.05.007. Epub 2013 May 29.

PMID:
23726864
11.

Bioluminescent assays for cytochrome P450 enzymes.

Auld DS, Veith H, Cali JJ.

Methods Mol Biol. 2013;987:1-9. doi: 10.1007/978-1-62703-321-3_1.

PMID:
23475663
12.

A bioluminescence assay for aldehyde dehydrogenase activity.

Duellman SJ, Valley MP, Kotraiah V, Vidugiriene J, Zhou W, Bernad L, Osterman J, Kimball JJ, Meisenheimer P, Cali JJ.

Anal Biochem. 2013 Mar 15;434(2):226-32. doi: 10.1016/j.ab.2012.11.016. Epub 2012 Dec 3.

PMID:
23219557
13.

Bioluminescent assays for ADME evaluation: dialing in CYP selectivity with luminogenic substrates.

Cali JJ, Ma D, Wood MG, Meisenheimer PL, Klaubert DH.

Expert Opin Drug Metab Toxicol. 2012 Sep;8(9):1115-30. doi: 10.1517/17425255.2012.695345. Epub 2012 Jun 11. Review.

PMID:
22686499
14.

Molecular imaging of cytochrome P450 activity in mice.

Roncoroni C, Rizzi N, Brunialti E, Cali JJ, Klaubert DH, Maggi A, Ciana P.

Pharmacol Res. 2012 May;65(5):531-6. doi: 10.1016/j.phrs.2012.02.006. Epub 2012 Feb 25.

PMID:
22391453
15.

Proluciferin acetals as bioluminogenic substrates for cytochrome P450 activity and probes for CYP3A inhibition.

Meisenheimer PL, Uyeda HT, Ma D, Sobol M, McDougall MG, Corona C, Simpson D, Klaubert DH, Cali JJ.

Drug Metab Dispos. 2011 Dec;39(12):2403-10. doi: 10.1124/dmd.111.041541. Epub 2011 Sep 2.

PMID:
21890735
16.

A bioluminescent assay for the sensitive detection of proteases.

Leippe DM, Nguyen D, Zhou M, Good T, Kirkland TA, Scurria M, Bernad L, Ugo T, Vidugiriene J, Cali JJ, Klaubert DH, O'Brien MA.

Biotechniques. 2011 Aug;51(2):105-10. doi: 10.2144/000113716.

17.

Automated triplexed hepatocyte-based viability and CYP1A and -3A induction assays.

Larson B, Moeller T, Banks P, Cali JJ.

J Biomol Screen. 2011 Sep;16(8):895-902. doi: 10.1177/1087057111411482. Epub 2011 Jun 21.

PMID:
21693767
18.

Automated luminescence-based cytochrome P450 profiling using a simple, elegant robotic platform.

Larson B, Banks P, Cali JJ, Sobol M, Shultz S.

J Lab Autom. 2011 Feb;16(1):47-55. doi: 10.1016/j.jala.2010.01.005. Epub 2010 Mar 19.

PMID:
21609685
19.

Automation and miniaturization of the bioluminescent UGT-Glo assay for screening of UDP-glucuronosyltransferase inhibition by various compounds.

Larson B, Kelts JL, Banks P, Cali JJ.

J Lab Autom. 2011 Feb;16(1):38-46. doi: 10.1016/j.jala.2010.05.005. Epub 2010 Jul 24.

PMID:
21609684
20.

The utility of semi-automating multiplexed assays for ADME/Tox applications.

Larson B, Banks P, Shultz S, Sobol M, Cali JJ.

Comb Chem High Throughput Screen. 2011 Sep;14(8):658-68.

PMID:
21564019
21.

International society for the study of xenobiotics - 11th European meeting.

Cali JJ.

IDrugs. 2009 Jul;12(7):424-7. No abstract available.

PMID:
19579161
22.

N-Alkylated 6'-aminoluciferins are bioluminescent substrates for Ultra-Glo and QuantiLum luciferase: new potential scaffolds for bioluminescent assays.

Woodroofe CC, Shultz JW, Wood MG, Osterman J, Cali JJ, Daily WJ, Meisenheimer PL, Klaubert DH.

Biochemistry. 2008 Sep 30;47(39):10383-93. doi: 10.1021/bi800505u. Epub 2008 Sep 5.

PMID:
18771284
24.

Bioluminescent assays for ADMET.

Cali JJ, Niles A, Valley MP, O'Brien MA, Riss TL, Shultz J.

Expert Opin Drug Metab Toxicol. 2008 Jan;4(1):103-20. doi: 10.1517/17425255.4.1.103 . Review.

PMID:
18370862
25.

Self-cleavable bioluminogenic luciferin phosphates as alkaline phosphatase reporters.

Zhou W, Andrews C, Liu J, Shultz JW, Valley MP, Cali JJ, Hawkins EM, Klaubert DH, Bulleit RF, Wood KV.

Chembiochem. 2008 Mar 25;9(5):714-8. doi: 10.1002/cbic.200700644. No abstract available.

PMID:
18247448
26.

A bioluminescent assay for monoamine oxidase activity.

Valley MP, Zhou W, Hawkins EM, Shultz J, Cali JJ, Worzella T, Bernad L, Good T, Good D, Riss TL, Klaubert DH, Wood KV.

Anal Biochem. 2006 Dec 15;359(2):238-46. Epub 2006 Oct 18.

PMID:
17084801
27.

Luminogenic cytochrome P450 assays.

Cali JJ, Ma D, Sobol M, Simpson DJ, Frackman S, Good TD, Daily WJ, Liu D.

Expert Opin Drug Metab Toxicol. 2006 Aug;2(4):629-45. Review.

PMID:
16859410
28.

Type VIII adenylyl cyclase in rat beta cells: coincidence signal detector/generator for glucose and GLP-1.

Delmeire D, Flamez D, Hinke SA, Cali JJ, Pipeleers D, Schuit F.

Diabetologia. 2003 Oct;46(10):1383-93. Epub 2003 Sep 17.

PMID:
13680124
29.

Dimerization of mammalian adenylate cyclases.

Gu C, Cali JJ, Cooper DM.

Eur J Biochem. 2002 Jan;269(2):413-21.

30.

Molecular diversity of the adenylyl cyclases.

Krupinski J, Cali JJ.

Adv Second Messenger Phosphoprotein Res. 1998;32:53-79. Review. No abstract available.

PMID:
9421585
31.

Isozyme-dependent sensitivity of adenylyl cyclases to P-site-mediated inhibition by adenine nucleosides and nucleoside 3'-polyphosphates.

Johnson RA, D├ęsaubry L, Bianchi G, Shoshani I, Lyons E Jr, Taussig R, Watson PA, Cali JJ, Krupinski J, Pieroni JP, Iyengar R.

J Biol Chem. 1997 Apr 4;272(14):8962-6.

32.
33.

Type VIII adenylyl cyclase. A Ca2+/calmodulin-stimulated enzyme expressed in discrete regions of rat brain.

Cali JJ, Zwaagstra JC, Mons N, Cooper DM, Krupinski J.

J Biol Chem. 1994 Apr 22;269(16):12190-5.

34.

Frameshift and splice-junction mutations in the sterol 27-hydroxylase gene cause cerebrotendinous xanthomatosis in Jews or Moroccan origin.

Leitersdorf E, Reshef A, Meiner V, Levitzki R, Schwartz SP, Dann EJ, Berkman N, Cali JJ, Klapholz L, Berginer VM.

J Clin Invest. 1993 Jun;91(6):2488-96.

35.
36.

Cloning of the human cholesterol 7 alpha-hydroxylase gene (CYP7) and localization to chromosome 8q11-q12.

Cohen JC, Cali JJ, Jelinek DF, Mehrabian M, Sparkes RS, Lusis AJ, Russell DW, Hobbs HH.

Genomics. 1992 Sep;14(1):153-61.

PMID:
1358792
37.

Mutations in the bile acid biosynthetic enzyme sterol 27-hydroxylase underlie cerebrotendinous xanthomatosis.

Cali JJ, Hsieh CL, Francke U, Russell DW.

J Biol Chem. 1991 Apr 25;266(12):7779-83.

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