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Items: 1 to 50 of 722

1.

Risk Factors Associated With a Noncontact Anterior Cruciate Ligament Injury to the Contralateral Knee After Unilateral Anterior Cruciate Ligament Injury in High School and College Female Athletes: A Prospective Study.

Davey AP, Vacek PM, Caldwell RA, Slauterbeck JR, Gardner-Morse MG, Tourville TW, Beynnon BD.

Am J Sports Med. 2019 Nov 5:363546519886260. doi: 10.1177/0363546519886260. [Epub ahead of print]

PMID:
31689130
2.

Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton's Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases.

Caldwell RD, Qiu H, Askew BC, Bender AT, Brugger N, Camps M, Dhanabal M, Dutt V, Eichhorn T, Gardberg AS, Goutopoulos A, Grenningloh R, Head J, Healey B, Hodous BL, Huck BR, Johnson TL, Jones C, Jones RC, Mochalkin I, Morandi F, Nguyen N, Meyring M, Potnick JR, Santos DC, Schmidt R, Sherer B, Shutes A, Urbahns K, Follis AV, Wegener AA, Zimmerli SC, Liu-Bujalski L.

J Med Chem. 2019 Sep 12;62(17):7643-7655. doi: 10.1021/acs.jmedchem.9b00794. Epub 2019 Aug 15.

PMID:
31368705
3.

Deletion of Arginase 2 Ameliorates Retinal Neurodegeneration in a Mouse Model of Multiple Sclerosis.

Palani CD, Fouda AY, Liu F, Xu Z, Mohamed E, Giri S, Smith SB, Caldwell RB, Narayanan SP.

Mol Neurobiol. 2019 Dec;56(12):8589-8602. doi: 10.1007/s12035-019-01691-w. Epub 2019 Jul 6.

PMID:
31280447
4.

Age-Dependent Oxidative Stress Elevates Arginase 1 and Uncoupled Nitric Oxide Synthesis in Skeletal Muscle of Aged Mice.

Pandya CD, Lee B, Toque HA, Mendhe B, Bragg RT, Pandya B, Atawia RT, Isales C, Hamrick M, Caldwell RW, Fulzele S.

Oxid Med Cell Longev. 2019 May 8;2019:1704650. doi: 10.1155/2019/1704650. eCollection 2019.

5.

Regulation of MAP kinase-mediated endothelial dysfunction in hyperglycemia via arginase I and eNOS dysregulation.

Mazrouei S, Sharifpanah F, Caldwell RW, Franz M, Shatanawi A, Muessig J, Fritzenwanger M, Schulze PC, Jung C.

Biochim Biophys Acta Mol Cell Res. 2019 Sep;1866(9):1398-1411. doi: 10.1016/j.bbamcr.2019.05.004. Epub 2019 May 28.

PMID:
31150695
6.

Chronic mild stress induced anxiety-like behaviors can Be attenuated by inhibition of NOX2-derived oxidative stress.

Lv H, Zhu C, Wu R, Ni H, Lian J, Xu Y, Xia Y, Shi G, Li Z, Caldwell RB, Caldwell RW, Yao L, Chen Y.

J Psychiatr Res. 2019 Jul;114:55-66. doi: 10.1016/j.jpsychires.2019.04.008. Epub 2019 Apr 23.

PMID:
31039481
7.

Synthesis and SAR development of quinoline analogs as novel P2X7 receptor antagonists.

Xiao Y, Karra S, Goutopoulos A, Morse NT, Zhang S, Dhanabal M, Tian H, Seenisamy J, Jayadevan J, Caldwell R, Potnick J, Bleich M, Chekler E, Sherer B, Sriraman V.

Bioorg Med Chem Lett. 2019 Jul 1;29(13):1660-1664. doi: 10.1016/j.bmcl.2019.04.033. Epub 2019 Apr 24.

PMID:
31031055
8.

Role of Arginase 2 in Systemic Metabolic Activity and Adipose Tissue Fatty Acid Metabolism in Diet-Induced Obese Mice.

Atawia RT, Toque HA, Meghil MM, Benson TW, Yiew NKH, Cutler CW, Weintraub NL, Caldwell RB, Caldwell RW.

Int J Mol Sci. 2019 Mar 22;20(6). pii: E1462. doi: 10.3390/ijms20061462.

9.

The TNF-derived TIP peptide activates the epithelial sodium channel and ameliorates experimental nephrotoxic serum nephritis.

Madaio MP, Czikora I, Kvirkvelia N, McMenamin M, Yue Q, Liu T, Toque HA, Sridhar S, Covington K, Alaisami R, O'Connor PM, Caldwell RW, Chen JK, Clauss M, Brands MW, Eaton DC, Romero MJ, Lucas R.

Kidney Int. 2019 Jun;95(6):1359-1372. doi: 10.1016/j.kint.2018.12.022. Epub 2019 Mar 21.

PMID:
30905471
10.

Mechanisms of obesity-induced metabolic and vascular dysfunctions.

Atawia RT, Bunch KL, Toque HA, Caldwell RB, Caldwell RW.

Front Biosci (Landmark Ed). 2019 Mar 1;24:890-934. Review.

11.

Polarisation signals: a new currency for communication.

Marshall NJ, Powell SB, Cronin TW, Caldwell RL, Johnsen S, Gruev V, Chiou TS, Roberts NW, How MJ.

J Exp Biol. 2019 Feb 7;222(Pt 3). pii: jeb134213. doi: 10.1242/jeb.134213. Review.

12.

Targeting Polyamine Oxidase to Prevent Excitotoxicity-Induced Retinal Neurodegeneration.

Pichavaram P, Palani CD, Patel C, Xu Z, Shosha E, Fouda AY, Caldwell RB, Narayanan SP.

Front Neurosci. 2019 Jan 10;12:956. doi: 10.3389/fnins.2018.00956. eCollection 2018.

13.

Cardiac allograft vasculopathy and graft failure in pediatric heart transplant recipients after rejection with severe hemodynamic compromise.

Kleinmahon JA, Gralla J, Kirk R, Auerbach SR, Henderson HT, Wallis GA, Ramakrishnan K, Singh RK, Caldwell RL, Savage AJ, Everitt MD.

J Heart Lung Transplant. 2019 Mar;38(3):277-284. doi: 10.1016/j.healun.2018.12.011. Epub 2018 Dec 21.

PMID:
30638837
14.

Retinal Neuroprotection From Optic Nerve Trauma by Deletion of Arginase 2.

Xu Z, Fouda AY, Lemtalsi T, Shosha E, Rojas M, Liu F, Patel C, Caldwell RW, Narayanan SP, Caldwell RB.

Front Neurosci. 2018 Dec 20;12:970. doi: 10.3389/fnins.2018.00970. eCollection 2018.

15.

Discovery of Affinity-Based Probes for Btk Occupancy Assays.

Qiu H, Caldwell R, Liu-Bujalski L, Goutopoulos A, Jones R, Potnick J, Sherer B, Bender A, Grenningloh R, Xu D, Gardberg A, Mochalkin I, Johnson T, Viacava Follis A, Head J, Morandi F.

ChemMedChem. 2019 Jan 22;14(2):217-223. doi: 10.1002/cmdc.201800714. Epub 2019 Jan 9.

PMID:
30521698
16.

Effects of Bronchopulmonary Dysplasia on Swallow:Breath Interaction and Phase of Respiration with Swallow During Non-nutritive Suck.

Reynolds EW, Grider D, Caldwell R, Capilouto G, Patwardhan A, Charnigo R.

J Nat Sci. 2018 Sep;4(9). pii: e531.

17.

Hyperglycemia-impaired aortic vasorelaxation mediated through arginase elevation: Role of stress kinase pathways.

Chandra S, Fulton DJR, Caldwell RB, Caldwell RW, Toque HA.

Eur J Pharmacol. 2019 Feb 5;844:26-37. doi: 10.1016/j.ejphar.2018.11.027. Epub 2018 Nov 28.

PMID:
30502342
18.

Discovery of a novel series of pyridine and pyrimidine carboxamides as potent and selective covalent inhibitors of Btk.

Caldwell R, Liu-Bujalski L, Qiu H, Mochalkin I, Jones R, Neagu C, Goutopoulos A, Grenningloh R, Johnson T, Sherer B, Gardberg A, Follis AV, Morandi F, Head J.

Bioorg Med Chem Lett. 2018 Nov 15;28(21):3419-3424. doi: 10.1016/j.bmcl.2018.09.033. Epub 2018 Sep 27.

PMID:
30290988
19.

Arginase 1 promotes retinal neurovascular protection from ischemia through suppression of macrophage inflammatory responses.

Fouda AY, Xu Z, Shosha E, Lemtalsi T, Chen J, Toque HA, Tritz R, Cui X, Stansfield BK, Huo Y, Rodriguez PC, Smith SB, Caldwell RW, Narayanan SP, Caldwell RB.

Cell Death Dis. 2018 Sep 25;9(10):1001. doi: 10.1038/s41419-018-1051-6.

20.

Mortality after deferral of treatment or no treatment for choroidal melanoma.

Straatsma BR, Diener-West M, Caldwell R, Engstrom RE; Collaborative Ocular Melanoma Study Group*.

Indian J Ophthalmol. 2018 Oct;66(10):1395-1400. doi: 10.4103/ijo.IJO_1499_18.

21.

Optimization of the efflux ratio and permeability of covalent irreversible BTK inhibitors.

Qiu H, Liu-Bujalski L, Caldwell RD, Viacava Follis A, Gardberg A, Goutopoulos A, Grenningloh R, Head J, Johnson T, Jones CCV, Jones R, Mochalkin I, Morandi F, Neagu C, Potnick J, Sherer B.

Bioorg Med Chem Lett. 2018 Nov 1;28(20):3307-3311. doi: 10.1016/j.bmcl.2018.09.018. Epub 2018 Sep 15.

PMID:
30243592
22.

Common Upper Extremity Fracture Eponyms: A Look Into What They Really Mean.

Caldwell RA, Shorten PL, Morrell NT.

J Hand Surg Am. 2019 Apr;44(4):331-334. doi: 10.1016/j.jhsa.2018.07.012. Epub 2018 Sep 18. Review.

PMID:
30241976
23.
24.

Homeless No More: A Christ-Centered, Comprehensive Homeless Recovery Program.

Caldwell R, Meraz R, Sweeney RR.

J Christ Nurs. 2018 Oct/Dec;35(4):228-233. doi: 10.1097/CNJ.0000000000000446.

PMID:
30199426
25.

Stakeholder perspectives for possible residual limb monitoring system for persons with lower-limb amputation.

Tran L, Caldwell R, Quigley M, Fatone S.

Disabil Rehabil. 2018 Sep 5:1-8. doi: 10.1080/09638288.2018.1492634. [Epub ahead of print]

PMID:
30182755
26.

Discovery of potent, highly selective covalent irreversible BTK inhibitors from a fragment hit.

Qiu H, Liu-Bujalski L, Caldwell RD, Follis AV, Gardberg A, Goutopoulos A, Grenningloh R, Head J, Johnson T, Jones R, Mochalkin I, Morandi F, Neagu C, Sherer B.

Bioorg Med Chem Lett. 2018 Sep 15;28(17):2939-2944. doi: 10.1016/j.bmcl.2018.07.008. Epub 2018 Jul 5.

PMID:
30122225
27.

Controllable protein phase separation and modular recruitment to form responsive membraneless organelles.

Schuster BS, Reed EH, Parthasarathy R, Jahnke CN, Caldwell RM, Bermudez JG, Ramage H, Good MC, Hammer DA.

Nat Commun. 2018 Jul 30;9(1):2985. doi: 10.1038/s41467-018-05403-1.

28.

Neurofibromin Deficiency Induces Endothelial Cell Proliferation and Retinal Neovascularization.

Zhang H, Hudson FZ, Xu Z, Tritz R, Rojas M, Patel C, Haigh SB, Bordán Z, Ingram DA, Fulton DJ, Weintraub NL, Caldwell RB, Stansfield BK.

Invest Ophthalmol Vis Sci. 2018 May 1;59(6):2520-2528. doi: 10.1167/iovs.17-22588.

29.

Infusing Social Justice in Undergraduate Nursing Education: Fostering Praxis Through Simulation.

Caldwell R, Cochran C.

J Forensic Nurs. 2018 Apr/Jun;14(2):88-97. doi: 10.1097/JFN.0000000000000198.

PMID:
29781968
30.

Enabling factors for specialist outreach in western KwaZulu-Natal.

Caldwell RI, Grant M, Gaede B, Aldous C.

Afr J Prim Health Care Fam Med. 2018 May 17;10(1):e1-e10. doi: 10.4102/phcfm.v10i1.1690.

31.

Change in residual limb size over time in the NU-FlexSIV socket: A case study.

Fatone S, Yohay J, Caldwell R.

Prosthet Orthot Int. 2018 Dec;42(6):620-625. doi: 10.1177/0309364618775445. Epub 2018 May 18.

PMID:
29775131
32.

Blockade of TREM-1 prevents vitreoretinal neovascularization in mice with oxygen-induced retinopathy.

Rojas MA, Shen ZT, Caldwell RB, Sigalov AB.

Biochim Biophys Acta Mol Basis Dis. 2018 Sep;1864(9 Pt B):2761-2768. doi: 10.1016/j.bbadis.2018.05.001. Epub 2018 May 3.

33.

Mechanisms of Diabetes-Induced Endothelial Cell Senescence: Role of Arginase 1.

Shosha E, Xu Z, Narayanan SP, Lemtalsi T, Fouda AY, Rojas M, Xing J, Fulton D, Caldwell RW, Caldwell RB.

Int J Mol Sci. 2018 Apr 17;19(4). pii: E1215. doi: 10.3390/ijms19041215.

34.

Optochemical Control of Protein Localization and Activity within Cell-like Compartments.

Caldwell RM, Bermudez JG, Thai D, Aonbangkhen C, Schuster BS, Courtney T, Deiters A, Hammer DA, Chenoweth DM, Good MC.

Biochemistry. 2018 May 8;57(18):2590-2596. doi: 10.1021/acs.biochem.8b00131. Epub 2018 Apr 19.

PMID:
29671583
35.

Gain-of-function analysis of cis-acting diversification elements in DT40 cells.

Caldwell RB, Braselmann H, Heuer S, Schötz U, Zitzelsberger H.

Immunol Cell Biol. 2018 Oct;96(9):948-957. doi: 10.1111/imcb.12158. Epub 2018 May 22.

PMID:
29665088
36.

A statewide program providing colorectal cancer screening to the uninsured of South Carolina.

Eberth JM, Thibault A, Caldwell R, Josey MJ, Qiang B, Peña E, LaFrance D, Berger FG.

Cancer. 2018 May 1;124(9):1912-1920. doi: 10.1002/cncr.31250. Epub 2018 Feb 7.

37.

Arginase: A Multifaceted Enzyme Important in Health and Disease.

Caldwell RW, Rodriguez PC, Toque HA, Narayanan SP, Caldwell RB.

Physiol Rev. 2018 Apr 1;98(2):641-665. doi: 10.1152/physrev.00037.2016. Review.

38.

Lung disease phenotypes caused by overexpression of combinations of α-, β-, and γ-subunits of the epithelial sodium channel in mouse airways.

Livraghi-Butrico A, Wilkinson KJ, Volmer AS, Gilmore RC, Rogers TD, Caldwell RA, Burns KA, Esther CR Jr, Mall MA, Boucher RC, O'Neal WK, Grubb BR.

Am J Physiol Lung Cell Mol Physiol. 2018 Feb 1;314(2):L318-L331. doi: 10.1152/ajplung.00382.2017. Epub 2017 Oct 26.

39.

Netrin-1 is a novel regulator of vascular endothelial function in diabetes.

Toque HA, Fernandez-Flores A, Mohamed R, Caldwell RB, Ramesh G, Caldwell RW.

PLoS One. 2017 Oct 23;12(10):e0186734. doi: 10.1371/journal.pone.0186734. eCollection 2017.

40.

Obesity-induced vascular dysfunction and arterial stiffening requires endothelial cell arginase 1.

Bhatta A, Yao L, Xu Z, Toque HA, Chen J, Atawia RT, Fouda AY, Bagi Z, Lucas R, Caldwell RB, Caldwell RW.

Cardiovasc Res. 2017 Nov 1;113(13):1664-1676. doi: 10.1093/cvr/cvx164. Erratum in: Cardiovasc Res. 2018 Jan 1;114(1):64.

41.

Correction: Diabetes-Induced Superoxide Anion and Breakdown of the Blood-Retinal Barrier: Role of the VEGF/uPAR Pathway.

El-Remessy AB, Franklin T, Ghaley N, Yang J, Brands MW, Caldwell RB, Behzadian MA.

PLoS One. 2017 Oct 16;12(10):e0186749. doi: 10.1371/journal.pone.0186749. eCollection 2017.

42.

Neural electrode resilience against dielectric damage may be improved by use of highly doped silicon as a conductive material.

Caldwell R, Sharma R, Takmakov P, Street MG, Solzbacher F, Tathireddy P, Rieth L.

J Neurosci Methods. 2018 Jan 1;293:210-225. doi: 10.1016/j.jneumeth.2017.10.002. Epub 2017 Oct 7.

PMID:
29017900
43.

Effect of fatigue on reading computed tomography examination of the multiply injured patient.

Krupinski EA, Schartz KM, Van Tassell MS, Madsen MT, Caldwell RT, Berbaum KS.

J Med Imaging (Bellingham). 2017 Jul;4(3):035504. doi: 10.1117/1.JMI.4.3.035504. Epub 2017 Sep 29.

44.

Irradiation biology of male brown marmorated stink bugs: is there scope for the sterile insect technique?

Welsh TJ, Stringer LD, Caldwell R, Carpenter JE, Suckling DM.

Int J Radiat Biol. 2017 Dec;93(12):1357-1363. doi: 10.1080/09553002.2017.1388547. Epub 2017 Nov 2.

PMID:
28978259
45.

Endothelial adenosine A2a receptor-mediated glycolysis is essential for pathological retinal angiogenesis.

Liu Z, Yan S, Wang J, Xu Y, Wang Y, Zhang S, Xu X, Yang Q, Zeng X, Zhou Y, Gu X, Lu S, Fu Z, Fulton DJ, Weintraub NL, Caldwell RB, Zhang W, Wu C, Liu XL, Chen JF, Ahmad A, Kaddour-Djebbar I, Al-Shabrawey M, Li Q, Jiang X, Sun Y, Sodhi A, Smith L, Hong M, Huo Y.

Nat Commun. 2017 Sep 19;8(1):584. doi: 10.1038/s41467-017-00551-2.

46.

Obesity-induced vascular inflammation involves elevated arginase activity.

Yao L, Bhatta A, Xu Z, Chen J, Toque HA, Chen Y, Xu Y, Bagi Z, Lucas R, Huo Y, Caldwell RB, Caldwell RW.

Am J Physiol Regul Integr Comp Physiol. 2017 Nov 1;313(5):R560-R571. doi: 10.1152/ajpregu.00529.2016. Epub 2017 Aug 23.

47.

NOX2-Induced Activation of Arginase and Diabetes-Induced Retinal Endothelial Cell Senescence.

Rojas M, Lemtalsi T, Toque HA, Xu Z, Fulton D, Caldwell RW, Caldwell RB.

Antioxidants (Basel). 2017 Jun 15;6(2). pii: E43. doi: 10.3390/antiox6020043.

48.

Role of Octreotide in Pediatric Gastrointestinal Bleeding Secondary to Angiodysplasia in Children With Right Heart Failure.

Puri K, Caldwell RL, Molleston JP.

J Pediatr Gastroenterol Nutr. 2018 Feb;66(2):e41-e44. doi: 10.1097/MPG.0000000000001659.

PMID:
28614113
49.

Mitochondrial targeting by dichloroacetate improves outcome following hemorrhagic shock.

Subramani K, Lu S, Warren M, Chu X, Toque HA, Caldwell RW, Diamond MP, Raju R.

Sci Rep. 2017 Jun 1;7(1):2671. doi: 10.1038/s41598-017-02495-5.

50.

The Impact of Fatigue on Satisfaction of Search in Chest Radiography.

Krupinski EA, Berbaum KS, Schartz KM, Caldwell RT, Madsen MT.

Acad Radiol. 2017 Sep;24(9):1058-1063. doi: 10.1016/j.acra.2017.03.021. Epub 2017 May 23.

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