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Items: 1 to 50 of 121

1.

Chlamydia trachomatis Lipopolysaccharide Evades the Canonical and Noncanonical Inflammatory Pathways To Subvert Innate Immunity.

Yang C, Briones M, Chiou J, Lei L, Patton MJ, Ma L, McClarty G, Caldwell HD.

MBio. 2019 Apr 23;10(2). pii: e00595-19. doi: 10.1128/mBio.00595-19.

2.

The Chlamydia trachomatis Plasmid and CT135 Virulence Factors Are Not Essential for Genital Tract Infection or Pathology in Female Pig-Tailed Macaques.

Patton DL, Sweeney YC, Baldessari AE, Cles L, Kari L, Sturdevant GL, Yang C, Caldwell HD.

Infect Immun. 2018 Apr 23;86(5). pii: e00121-18. doi: 10.1128/IAI.00121-18. Print 2018 May.

3.

Plasmid Negative Regulation of CPAF Expression Is Pgp4 Independent and Restricted to Invasive Chlamydia trachomatis Biovars.

Patton MJ, Chen CY, Yang C, McCorrister S, Grant C, Westmacott G, Yuan XY, Ochoa E, Fariss R, Whitmire WM, Carlson JH, Caldwell HD, McClarty G.

MBio. 2018 Jan 30;9(1). pii: e02164-17. doi: 10.1128/mBio.02164-17.

4.

Infection of Hysterectomized Mice with Chlamydia muridarum and Chlamydia trachomatis.

Yang C, Whitmire WM, Sturdevant GL, Bock K, Moore I, Caldwell HD.

Infect Immun. 2017 Jun 20;85(7). pii: e00197-17. doi: 10.1128/IAI.00197-17. Print 2017 Jul.

5.

PATIENT WEB PORTALS AND PATIENT-PROVIDER RELATIONSHIPS: A SUMMARY PERSPECTIVE.

Caldwell HD, Minkoff NB, Murthy K.

Int J Technol Assess Health Care. 2017 Jan;33(1):63-68. doi: 10.1017/S0266462317000137. Epub 2017 Apr 24.

PMID:
28434422
6.

Chlamydia trachomatis ChxR is a transcriptional regulator of virulence factors that function in in vivo host-pathogen interactions.

Yang C, Kari L, Sturdevant GL, Song L, Patton MJ, Couch CE, Ilgenfritz JM, Southern TR, Whitmire WM, Briones M, Bonner C, Grant C, Hu P, McClarty G, Caldwell HD.

Pathog Dis. 2017 Apr 1;75(3). doi: 10.1093/femspd/ftx035.

7.

Chlamydial Protease-Like Activity Factor and Type III Secreted Effectors Cooperate in Inhibition of p65 Nuclear Translocation.

Patton MJ, McCorrister S, Grant C, Westmacott G, Fariss R, Hu P, Zhao K, Blake M, Whitmire B, Yang C, Caldwell HD, McClarty G.

MBio. 2016 Sep 27;7(5). pii: e01427-16. doi: 10.1128/mBio.01427-16.

8.

Chlamydial Lytic Exit from Host Cells Is Plasmid Regulated.

Yang C, Starr T, Song L, Carlson JH, Sturdevant GL, Beare PA, Whitmire WM, Caldwell HD.

MBio. 2015 Nov 10;6(6):e01648-15. doi: 10.1128/mBio.01648-15.

9.

A Chlamydia trachomatis strain with a chemically generated amino acid substitution (P370L) in the cthtrA gene shows reduced elementary body production.

Marsh JW, Wee BA, Tyndall JD, Lott WB, Bastidas RJ, Caldwell HD, Valdivia RH, Kari L, Huston WM.

BMC Microbiol. 2015 Sep 30;15:194. doi: 10.1186/s12866-015-0533-2.

10.

Chlamydia trachomatis virulence factor CT135 is stable in vivo but highly polymorphic in vitro.

Bonner C, Caldwell HD, Carlson JH, Graham MR, Kari L, Sturdevant GL, Tyler S, Zetner A, McClarty G.

Pathog Dis. 2015 Aug;73(6):ftv043. doi: 10.1093/femspd/ftv043. Epub 2015 Jun 24.

11.

Transcriptional profiling of human epithelial cells infected with plasmid-bearing and plasmid-deficient Chlamydia trachomatis.

Porcella SF, Carlson JH, Sturdevant DE, Sturdevant GL, Kanakabandi K, Virtaneva K, Wilder H, Whitmire WM, Song L, Caldwell HD.

Infect Immun. 2015 Feb;83(2):534-43. doi: 10.1128/IAI.02764-14. Epub 2014 Nov 17.

12.

Benzylidene acylhydrazides inhibit chlamydial growth in a type III secretion- and iron chelation-independent manner.

Bao X, Gylfe A, Sturdevant GL, Gong Z, Xu S, Caldwell HD, Elofsson M, Fan H.

J Bacteriol. 2014 Aug 15;196(16):2989-3001. doi: 10.1128/JB.01677-14. Epub 2014 Jun 9.

13.

Chlamydia trachomatis polymorphic membrane protein D is a virulence factor involved in early host-cell interactions.

Kari L, Southern TR, Downey CJ, Watkins HS, Randall LB, Taylor LD, Sturdevant GL, Whitmire WM, Caldwell HD.

Infect Immun. 2014 Jul;82(7):2756-62. doi: 10.1128/IAI.01686-14. Epub 2014 Apr 14.

14.

CD8+ T cells define an unexpected role in live-attenuated vaccine protective immunity against Chlamydia trachomatis infection in macaques.

Olivares-Zavaleta N, Whitmire WM, Kari L, Sturdevant GL, Caldwell HD.

J Immunol. 2014 May 15;192(10):4648-54. doi: 10.4049/jimmunol.1400120. Epub 2014 Apr 7.

15.

Innate immunity is sufficient for the clearance of Chlamydia trachomatis from the female mouse genital tract.

Sturdevant GL, Caldwell HD.

Pathog Dis. 2014 Oct;72(1):70-3. doi: 10.1111/2049-632X.12164. Epub 2014 Apr 10.

16.

Infectivity of urogenital Chlamydia trachomatis plasmid-deficient, CT135-null, and double-deficient strains in female mice.

Sturdevant GL, Zhou B, Carlson JH, Whitmire WM, Song L, Caldwell HD.

Pathog Dis. 2014 Jun;71(1):90-2. doi: 10.1111/2049-632X.12121. Epub 2014 Jan 13.

17.

Plasmid-mediated transformation tropism of chlamydial biovars.

Song L, Carlson JH, Zhou B, Virtaneva K, Whitmire WM, Sturdevant GL, Porcella SF, McClarty G, Caldwell HD.

Pathog Dis. 2014 Mar;70(2):189-93. doi: 10.1111/2049-632X.12104. Epub 2013 Nov 11.

18.

Antibody signature of spontaneous clearance of Chlamydia trachomatis ocular infection and partial resistance against re-challenge in a nonhuman primate trachoma model.

Kari L, Bakios LE, Goheen MM, Bess LN, Watkins HS, Southern TR, Song L, Whitmire WM, Olivares-Zavaleta N, Caldwell HD.

PLoS Negl Trop Dis. 2013 May 30;7(5):e2248. doi: 10.1371/journal.pntd.0002248. Print 2013.

19.

Chlamydia trachomatis plasmid-encoded Pgp4 is a transcriptional regulator of virulence-associated genes.

Song L, Carlson JH, Whitmire WM, Kari L, Virtaneva K, Sturdevant DE, Watkins H, Zhou B, Sturdevant GL, Porcella SF, McClarty G, Caldwell HD.

Infect Immun. 2013 Mar;81(3):636-44. doi: 10.1128/IAI.01305-12. Epub 2013 Jan 14.

20.

A live-attenuated chlamydial vaccine protects against trachoma in nonhuman primates.

Kari L, Whitmire WM, Olivares-Zavaleta N, Goheen MM, Taylor LD, Carlson JH, Sturdevant GL, Lu C, Bakios LE, Randall LB, Parnell MJ, Zhong G, Caldwell HD.

J Exp Med. 2011 Oct 24;208(11):2217-23. doi: 10.1084/jem.20111266. Epub 2011 Oct 10.

21.

Development of a pigtail macaque model of sexually transmitted infection/HIV coinfection using Chlamydia trachomatis, Trichomonas vaginalis, and SHIV(SF162P3).

Henning T, Fakile Y, Phillips C, Sweeney E, Mitchell J, Patton D, Sturdevant G, Caldwell HD, Secor WE, Papp J, Hendry RM, McNicholl J, Kersh E.

J Med Primatol. 2011 Aug;40(4):214-23. doi: 10.1111/j.1600-0684.2011.00488.x.

22.

Chlamydia pneumoniae inhibits activated human T lymphocyte proliferation by the induction of apoptotic and pyroptotic pathways.

Olivares-Zavaleta N, Carmody A, Messer R, Whitmire WM, Caldwell HD.

J Immunol. 2011 Jun 15;186(12):7120-6. doi: 10.4049/jimmunol.1100393. Epub 2011 May 4.

23.

Generation of targeted Chlamydia trachomatis null mutants.

Kari L, Goheen MM, Randall LB, Taylor LD, Carlson JH, Whitmire WM, Virok D, Rajaram K, Endresz V, McClarty G, Nelson DE, Caldwell HD.

Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7189-93. doi: 10.1073/pnas.1102229108. Epub 2011 Apr 11.

24.

Frameshift mutations in a single novel virulence factor alter the in vivo pathogenicity of Chlamydia trachomatis for the female murine genital tract.

Sturdevant GL, Kari L, Gardner DJ, Olivares-Zavaleta N, Randall LB, Whitmire WM, Carlson JH, Goheen MM, Selleck EM, Martens C, Caldwell HD.

Infect Immun. 2010 Sep;78(9):3660-8. doi: 10.1128/IAI.00386-10. Epub 2010 Jun 14.

25.

Biological characterization of Chlamydia trachomatis plasticity zone MACPF domain family protein CT153.

Taylor LD, Nelson DE, Dorward DW, Whitmire WM, Caldwell HD.

Infect Immun. 2010 Jun;78(6):2691-9. doi: 10.1128/IAI.01455-09. Epub 2010 Mar 29.

26.

Immunization with the attenuated plasmidless Chlamydia trachomatis L2(25667R) strain provides partial protection in a murine model of female genitourinary tract infection.

Olivares-Zavaleta N, Whitmire W, Gardner D, Caldwell HD.

Vaccine. 2010 Feb 10;28(6):1454-62. doi: 10.1016/j.vaccine.2009.11.073. Epub 2009 Dec 8.

27.

Chlamydia trachomatis native major outer membrane protein induces partial protection in nonhuman primates: implication for a trachoma transmission-blocking vaccine.

Kari L, Whitmire WM, Crane DD, Reveneau N, Carlson JH, Goheen MM, Peterson EM, Pal S, de la Maza LM, Caldwell HD.

J Immunol. 2009 Jun 15;182(12):8063-70. doi: 10.4049/jimmunol.0804375.

28.

Chlamydia trachomatis polymorphic membrane protein D is an oligomeric autotransporter with a higher-order structure.

Swanson KA, Taylor LD, Frank SD, Sturdevant GL, Fischer ER, Carlson JH, Whitmire WM, Caldwell HD.

Infect Immun. 2009 Jan;77(1):508-16. doi: 10.1128/IAI.01173-08. Epub 2008 Nov 10.

29.

The Chlamydia trachomatis plasmid is a transcriptional regulator of chromosomal genes and a virulence factor.

Carlson JH, Whitmire WM, Crane DD, Wicke L, Virtaneva K, Sturdevant DE, Kupko JJ 3rd, Porcella SF, Martinez-Orengo N, Heinzen RA, Kari L, Caldwell HD.

Infect Immun. 2008 Jun;76(6):2273-83. doi: 10.1128/IAI.00102-08. Epub 2008 Mar 17.

30.

Pathogenic diversity among Chlamydia trachomatis ocular strains in nonhuman primates is affected by subtle genomic variations.

Kari L, Whitmire WM, Carlson JH, Crane DD, Reveneau N, Nelson DE, Mabey DC, Bailey RL, Holland MJ, McClarty G, Caldwell HD.

J Infect Dis. 2008 Feb 1;197(3):449-56. doi: 10.1086/525285.

PMID:
18199030
31.

Chlamydia trachomatis species-specific induction of ezrin tyrosine phosphorylation functions in pathogen entry.

Swanson KA, Crane DD, Caldwell HD.

Infect Immun. 2007 Dec;75(12):5669-77. Epub 2007 Oct 1.

32.

Phenotypic rescue of Chlamydia trachomatis growth in IFN-gamma treated mouse cells by irradiated Chlamydia muridarum.

Nelson DE, Taylor LD, Shannon JG, Whitmire WM, Crane DD, McClarty G, Su H, Kari L, Caldwell HD.

Cell Microbiol. 2007 Sep;9(9):2289-98. Epub 2007 May 15.

PMID:
17501981
33.

Chlamydial interferon gamma immune evasion influences infection tropism.

McClarty G, Caldwell HD, Nelson DE.

Curr Opin Microbiol. 2007 Feb;10(1):47-51. Epub 2007 Jan 5. Review.

PMID:
17208039
34.

In vivo and in vitro studies of Chlamydia trachomatis TrpR:DNA interactions.

Carlson JH, Wood H, Roshick C, Caldwell HD, McClarty G.

Mol Microbiol. 2006 Mar;59(6):1678-91.

35.

Chlamydia trachomatis polymorphic membrane protein D is a species-common pan-neutralizing antigen.

Crane DD, Carlson JH, Fischer ER, Bavoil P, Hsia RC, Tan C, Kuo CC, Caldwell HD.

Proc Natl Acad Sci U S A. 2006 Feb 7;103(6):1894-9. Epub 2006 Jan 30.

36.

Comparison of gamma interferon-mediated antichlamydial defense mechanisms in human and mouse cells.

Roshick C, Wood H, Caldwell HD, McClarty G.

Infect Immun. 2006 Jan;74(1):225-38.

37.

Inhibition of chlamydiae by primary alcohols correlates with the strain-specific complement of plasticity zone phospholipase D genes.

Nelson DE, Crane DD, Taylor LD, Dorward DW, Goheen MM, Caldwell HD.

Infect Immun. 2006 Jan;74(1):73-80.

38.

Comparative genomic analysis of Chlamydia trachomatis oculotropic and genitotropic strains.

Carlson JH, Porcella SF, McClarty G, Caldwell HD.

Infect Immun. 2005 Oct;73(10):6407-18.

39.

Chlamydial IFN-gamma immune evasion is linked to host infection tropism.

Nelson DE, Virok DP, Wood H, Roshick C, Johnson RM, Whitmire WM, Crane DD, Steele-Mortimer O, Kari L, McClarty G, Caldwell HD.

Proc Natl Acad Sci U S A. 2005 Jul 26;102(30):10658-63. Epub 2005 Jul 14.

40.
41.

Chlamydial infection induces pathobiotype-specific protein tyrosine phosphorylation in epithelial cells.

Virok DP, Nelson DE, Whitmire WM, Crane DD, Goheen MM, Caldwell HD.

Infect Immun. 2005 Apr;73(4):1939-46.

42.

Polymorphisms in the Chlamydia trachomatis cytotoxin locus associated with ocular and genital isolates.

Carlson JH, Hughes S, Hogan D, Cieplak G, Sturdevant DE, McClarty G, Caldwell HD, Belland RJ.

Infect Immun. 2004 Dec;72(12):7063-72.

43.

Transcriptome analysis of chlamydial growth during IFN-gamma-mediated persistence and reactivation.

Belland RJ, Nelson DE, Virok D, Crane DD, Hogan D, Sturdevant D, Beatty WL, Caldwell HD.

Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15971-6. Epub 2003 Dec 12.

44.

Genotypic differences in the Chlamydia pneumoniae tyrP locus related to vascular tropism and pathogenicity.

Gieffers J, Durling L, Ouellette SP, Rupp J, Maass M, Byrne GI, Caldwell HD, Belland RJ.

J Infect Dis. 2003 Oct 15;188(8):1085-93. Epub 2003 Oct 10.

PMID:
14551876
45.

Micromanipulation of the Chlamydia pneumoniae inclusion: implications for cloning and host-pathogen interactions.

Gieffers J, Tamplin V, Maass M, Belland RJ, Caldwell HD.

FEMS Microbiol Lett. 2003 Sep 12;226(1):45-9.

46.

Genomic transcriptional profiling of the developmental cycle of Chlamydia trachomatis.

Belland RJ, Zhong G, Crane DD, Hogan D, Sturdevant D, Sharma J, Beatty WL, Caldwell HD.

Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8478-83. Epub 2003 Jun 18.

47.

Polymorphisms in Chlamydia trachomatis tryptophan synthase genes differentiate between genital and ocular isolates.

Caldwell HD, Wood H, Crane D, Bailey R, Jones RB, Mabey D, Maclean I, Mohammed Z, Peeling R, Roshick C, Schachter J, Solomon AW, Stamm WE, Suchland RJ, Taylor L, West SK, Quinn TC, Belland RJ, McClarty G.

J Clin Invest. 2003 Jun;111(11):1757-69.

48.

Isolation of Chlamydia pneumoniae clonal variants by a focus-forming assay.

Gieffers J, Belland RJ, Whitmire W, Ouellette S, Crane D, Maass M, Byrne GI, Caldwell HD.

Infect Immun. 2002 Oct;70(10):5827-34.

49.

Molecular basis defining human Chlamydia trachomatis tissue tropism. A possible role for tryptophan synthase.

Fehlner-Gardiner C, Roshick C, Carlson JH, Hughes S, Belland RJ, Caldwell HD, McClarty G.

J Biol Chem. 2002 Jul 26;277(30):26893-903. Epub 2002 May 13.

50.

Immunity to murine chlamydial genital infection.

Morrison RP, Caldwell HD.

Infect Immun. 2002 Jun;70(6):2741-51. Review. No abstract available.

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