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Items: 1 to 50 of 94

1.

Association study of single nucleotide polymorphisms in IL-10 and IL-17 genes with the severity of microbial keratitis.

Carnt NA, Cipriani V, Stapleton FJ, Calder V, Willcox MD.

Cont Lens Anterior Eye. 2019 Dec;42(6):658-661. doi: 10.1016/j.clae.2019.06.007. Epub 2019 Jul 5.

PMID:
31280929
2.

Automated Ocular Surface Image Analysis and Health-Related Quality of Life Utility Tool to Measure Blepharokeratoconjunctivitis Activity in Children.

Al-Hayouti H, Daniel M, Hingorani M, Calder V, Dahlmann-Noor A.

Cornea. 2019 Nov;38(11):1418-1423. doi: 10.1097/ICO.0000000000002042.

PMID:
31259862
3.

Meibography and corneal volume optical coherence tomography to quantify damage to ocular structures in children with blepharokeratoconjunctivitis.

Al-Hayouti H, Daniel M, Hingorani M, Calder V, Dahlmann-Noor A.

Acta Ophthalmol. 2019 Nov;97(7):e981-e986. doi: 10.1111/aos.14124. Epub 2019 Apr 25.

PMID:
31021059
4.

Management of ocular allergy.

Leonardi A, Silva D, Perez Formigo D, Bozkurt B, Sharma V, Allegri P, Rondon C, Calder V, Ryan D, Kowalski ML, Delgado L, Doan S, Fauquert JL.

Allergy. 2019 Sep;74(9):1611-1630. doi: 10.1111/all.13786. Epub 2019 Jun 24.

PMID:
30887530
5.

A Review of the Cytokine IL-17 in Ocular Surface and Corneal Disease.

Garbutcheon-Singh KB, Carnt N, Pattamatta U, Samarawickrama C, White A, Calder V.

Curr Eye Res. 2019 Jan;44(1):1-10. doi: 10.1080/02713683.2018.1519834. Epub 2018 Sep 19.

PMID:
30230384
6.

Clinical Remission of Sight-Threatening Non-Infectious Uveitis Is Characterized by an Upregulation of Peripheral T-Regulatory Cell Polarized Towards T-bet and TIGIT.

Gilbert RM, Zhang X, Sampson RD, Ehrenstein MR, Nguyen DX, Chaudhry M, Mein C, Mahmud N, Galatowicz G, Tomkins-Netzer O, Calder VL, Lightman S.

Front Immunol. 2018 May 3;9:907. doi: 10.3389/fimmu.2018.00907. eCollection 2018.

7.

Severity, therapeutic, and activity tear biomarkers in dry eye disease: An analysis from a phase III clinical trial.

Pinto-Fraga J, Enríquez-de-Salamanca A, Calonge M, González-García MJ, López-Miguel A, López-de la Rosa A, García-Vázquez C, Calder V, Stern ME, Fernández I.

Ocul Surf. 2018 Jul;16(3):368-376. doi: 10.1016/j.jtos.2018.05.001. Epub 2018 May 14.

PMID:
29772277
8.

Tear Cytokine Levels in Contact Lens Wearers With Acanthamoeba Keratitis.

Carnt N, Montanez VM, Galatowicz G, Veli N, Calder V.

Cornea. 2017 Jul;36(7):791-798. doi: 10.1097/ICO.0000000000001238.

PMID:
28489721
9.

Diagnostic tools in ocular allergy.

Leonardi A, Doan S, Fauquert JL, Bozkurt B, Allegri P, Marmouz F, Rondon C, Jedrzejczak M, Hellings P, Delgado L, Calder V.

Allergy. 2017 Oct;72(10):1485-1498. doi: 10.1111/all.13178. Epub 2017 May 10. Review.

PMID:
28387947
10.

Pharmacological Inhibition of Bromodomain Proteins Suppresses Retinal Inflammatory Disease and Downregulates Retinal Th17 Cells.

Eskandarpour M, Alexander R, Adamson P, Calder VL.

J Immunol. 2017 Feb 1;198(3):1093-1103. doi: 10.4049/jimmunol.1600735. Epub 2016 Dec 30.

11.

Aldehyde dehydrogenase inhibition blocks mucosal fibrosis in human and mouse ocular scarring.

Ahadome SD, Abraham DJ, Rayapureddi S, Saw VP, Saban DR, Calder VL, Norman JT, Ponticos M, Daniels JT, Dart JK.

JCI Insight. 2016 Aug 4;1(12):e87001. doi: 10.1172/jci.insight.87001.

12.

Classical dendritic cells mediate fibrosis directly via the retinoic acid pathway in severe eye allergy.

Ahadome SD, Mathew R, Reyes NJ, Mettu PS, Cousins SW, Calder VL, Saban DR.

JCI Insight. 2016 Aug 4;1(12). pii: 87012. doi: 10.1172/jci.insight.87012.

13.

Conjunctival allergen provocation test : guidelines for daily practice.

Fauquert JL, Jedrzejczak-Czechowicz M, Rondon C, Calder V, Silva D, Kvenshagen BK, Callebaut I, Allegri P, Santos N, Doan S, Perez Formigo D, Chiambaretta F, Delgado L, Leonardi A; Interest Group on Ocular Allergy (IGOA) from the European Academy of Allergy and Clinical Immunology.

Allergy. 2017 Jan;72(1):43-54. doi: 10.1111/all.12986. Epub 2016 Aug 18. Review.

PMID:
27430124
14.

T-bet Activates Th1 Genes through Mediator and the Super Elongation Complex.

Hertweck A, Evans CM, Eskandarpour M, Lau JC, Oleinika K, Jackson I, Kelly A, Ambrose J, Adamson P, Cousins DJ, Lavender P, Calder VL, Lord GM, Jenner RG.

Cell Rep. 2016 Jun 21;15(12):2756-70. doi: 10.1016/j.celrep.2016.05.054. Epub 2016 Jun 9.

15.

Quiescent and Active Tear Protein Profiles to Predict Vernal Keratoconjunctivitis Reactivation.

Micera A, Di Zazzo A, Esposito G, Sgrulletta R, Calder VL, Bonini S.

Biomed Res Int. 2016;2016:9672082. doi: 10.1155/2016/9672082. Epub 2016 Feb 17.

16.

TNFα Regulates SIRT1 Cleavage during Ocular Autoimmune Disease.

Gardner PJ, Yazid S, Chu CJ, Copland DA, Adamson P, Dick AD, Calder VL.

Am J Pathol. 2015 May;185(5):1324-33. doi: 10.1016/j.ajpath.2015.01.017. Epub 2015 Mar 12.

17.

Pegylated interferon-α-2b reduces corticosteroid requirement in patients with Behçet's disease with upregulation of circulating regulatory T cells and reduction of Th17.

Lightman S, Taylor SR, Bunce C, Longhurst H, Lynn W, Moots R, Stanford M, Tomkins-Netzer O, Yang D, Calder VL, Haskard DO.

Ann Rheum Dis. 2015 Jun;74(6):1138-44. doi: 10.1136/annrheumdis-2014-205571. Epub 2014 Sep 30.

18.

Effect of high-dose simvastatin on brain atrophy and disability in secondary progressive multiple sclerosis (MS-STAT): a randomised, placebo-controlled, phase 2 trial.

Chataway J, Schuerer N, Alsanousi A, Chan D, MacManus D, Hunter K, Anderson V, Bangham CR, Clegg S, Nielsen C, Fox NC, Wilkie D, Nicholas JM, Calder VL, Greenwood J, Frost C, Nicholas R.

Lancet. 2014 Jun 28;383(9936):2213-21. doi: 10.1016/S0140-6736(13)62242-4. Epub 2014 Mar 19.

19.

Statin Modulation of Human T-Cell Proliferation, IL-1β and IL-17 Production, and IFN-γ T Cell Expression: Synergy with Conventional Immunosuppressive Agents.

Jameel A, Ooi KG, Jeffs NR, Galatowicz G, Lightman SL, Calder VL.

Int J Inflam. 2013;2013:434586. doi: 10.1155/2013/434586. Epub 2013 Sep 18.

20.

The anti-inflammatory effects of therapies for ocular allergy.

Mantelli F, Calder VL, Bonini S.

J Ocul Pharmacol Ther. 2013 Nov;29(9):786-93. doi: 10.1089/jop.2013.0161. Epub 2013 Sep 17. Review.

PMID:
24044620
21.

Mitochondrial permeability transition pore in inflammatory apoptosis of human conjunctival epithelial cells and T cells: effect of cyclosporin A.

Gao J, Sana R, Calder V, Calonge M, Lee W, Wheeler LA, Stern ME.

Invest Ophthalmol Vis Sci. 2013 Jul 16;54(7):4717-33. doi: 10.1167/iovs.13-11681.

PMID:
23778874
22.

Anti-allergic cromones inhibit histamine and eicosanoid release from activated human and murine mast cells by releasing Annexin A1.

Yazid S, Sinniah A, Solito E, Calder V, Flower RJ.

PLoS One. 2013;8(3):e58963. doi: 10.1371/journal.pone.0058963. Epub 2013 Mar 18.

23.

SIRT1 activation protects against autoimmune T cell-driven retinal disease in mice via inhibition of IL-2/Stat5 signaling.

Gardner PJ, Joshi L, Lee RW, Dick AD, Adamson P, Calder VL.

J Autoimmun. 2013 May;42:117-29. doi: 10.1016/j.jaut.2013.01.011. Epub 2013 Feb 8.

PMID:
23395551
24.

New twists to an old story: novel concepts in the pathogenesis of allergic eye disease.

Saban DR, Calder V, Kuo CH, Reyes NJ, Dartt DA, Ono SJ, Niederkorn JY.

Curr Eye Res. 2013 Mar;38(3):317-30. doi: 10.3109/02713683.2012.747617. Epub 2013 Jan 2. Review.

25.

Effect of TGF-β on ocular surface epithelial cells.

Benito MJ, Calder V, Corrales RM, García-Vázquez C, Narayanan S, Herreras JM, Stern ME, Calonge M, Enríquez-de-Salamanca A.

Exp Eye Res. 2013 Feb;107:88-100. doi: 10.1016/j.exer.2012.11.017. Epub 2012 Dec 7.

PMID:
23220729
26.

Autoantibodies contribute to the immunopathogenesis of experimental dry eye disease.

Stern ME, Schaumburg CS, Siemasko KF, Gao J, Wheeler LA, Grupe DA, De Paiva CS, Calder VL, Calonge M, Niederkorn JY, Pflugfelder SC.

Invest Ophthalmol Vis Sci. 2012 Apr 24;53(4):2062-75. doi: 10.1167/iovs.11-9299.

27.

Profibrotic phenotype of conjunctival fibroblasts from mucous membrane pemphigoid.

Saw VP, Schmidt E, Offiah I, Galatowicz G, Zillikens D, Dart JK, Calder VL, Daniels JT.

Am J Pathol. 2011 Jan;178(1):187-97. doi: 10.1016/j.ajpath.2010.11.013. Epub 2010 Dec 23.

28.

IL6 and the human limbal stem cell niche: a mediator of epithelial-stromal interaction.

Notara M, Shortt AJ, Galatowicz G, Calder V, Daniels JT.

Stem Cell Res. 2010 Nov;5(3):188-200. doi: 10.1016/j.scr.2010.07.002. Epub 2010 Aug 3.

29.

Atopic keratoconjunctivitis and atopic dermatitis.

Guglielmetti S, Dart JK, Calder V.

Curr Opin Allergy Clin Immunol. 2010 Oct;10(5):478-85. doi: 10.1097/ACI.0b013e32833e16e4. Review.

PMID:
20720488
30.

Conjunctival interleukin-13 expression in mucous membrane pemphigoid and functional effects of interleukin-13 on conjunctival fibroblasts in vitro.

Saw VP, Offiah I, Dart RJ, Galatowicz G, Dart JK, Daniels JT, Calder VL.

Am J Pathol. 2009 Dec;175(6):2406-15. doi: 10.2353/ajpath.2009.090579. Epub 2009 Nov 12.

31.

Immune mechanisms in allergic eye diseases: what is new?

Offiah I, Calder VL.

Curr Opin Allergy Clin Immunol. 2009 Oct;9(5):477-81. doi: 10.1097/ACI.0b013e3283303e2e. Review.

PMID:
19620858
32.

Tumor necrosis factor-alpha in ocular mucous membrane pemphigoid and its effect on conjunctival fibroblasts.

Saw VP, Dart RJ, Galatowicz G, Daniels JT, Dart JK, Calder VL.

Invest Ophthalmol Vis Sci. 2009 Nov;50(11):5310-7. doi: 10.1167/iovs.08-3345. Epub 2009 Jun 3.

PMID:
19494201
33.

Cytokine responses by conjunctival epithelial cells: an in vitro model of ocular inflammation.

Enríquez-de-Salamanca A, Calder V, Gao J, Galatowicz G, García-Vázquez C, Fernández I, Stern ME, Diebold Y, Calonge M.

Cytokine. 2008 Oct;44(1):160-7. doi: 10.1016/j.cyto.2008.07.007. Epub 2008 Aug 28.

PMID:
18760623
34.

In vitro expanded CD4+CD25+Foxp3+ regulatory T cells maintain a normal phenotype and suppress immune-mediated ocular surface inflammation.

Siemasko KF, Gao J, Calder VL, Hanna R, Calonge M, Pflugfelder SC, Niederkorn JY, Stern ME.

Invest Ophthalmol Vis Sci. 2008 Dec;49(12):5434-40. doi: 10.1167/iovs.08-2075. Epub 2008 Jul 24.

PMID:
18658093
35.

Ocular anti-allergic compounds selectively inhibit human mast cell cytokines in vitro and conjunctival cell infiltration in vivo.

Galatowicz G, Ajayi Y, Stern ME, Calder VL.

Clin Exp Allergy. 2007 Nov;37(11):1648-56. Epub 2007 Sep 17.

PMID:
17877767
36.

Cytokine profiles in conjunctival allergy and inflammation.

Calder VL.

Ocul Surf. 2005 Oct;3(4 Suppl):S142-4.

PMID:
17216104
37.

Pathways of corneal and ocular surface inflammation: a perspective from the cullen symposium.

McDermott AM, Perez V, Huang AJ, Pflugfelder SC, Stern ME, Baudouin C, Beuerman RW, Burns AR, Calder VL, Calonge M, Chodosh J, Coster DJ, Dana R, Hazlett LD, Jones DB, Kim SK, Knop E, Li DQ, Mitchell BM, Niederkorn JY, Pearlman E, Wilhelmus KR, Kurie E.

Ocul Surf. 2005 Oct;3(4 Suppl):S131-8.

PMID:
17216102
38.

Cytokines and chemokines in uveitis: is there a correlation with clinical phenotype?

Ooi KG, Galatowicz G, Calder VL, Lightman SL.

Clin Med Res. 2006 Dec;4(4):294-309. Review.

39.

Normalized CD8+ but not CD4+ lymphocyte IL-2 expression is associated with early treatment with highly active antiretroviral therapy.

Akerele T, Galatowicz G, Bunce C, Calder V, Lynn WA, Lightman S.

Clin Immunol. 2006 Nov;121(2):191-7. Epub 2006 Sep 20.

PMID:
16987710
40.

Is IL-10 a good target to inhibit choroidal neovascularisation in age-related macular disease?

Lightman S, Calder V.

PLoS Med. 2006 Aug;3(8):e364. No abstract available.

41.

Multiple cytokines in human tear specimens in seasonal and chronic allergic eye disease and in conjunctival fibroblast cultures.

Leonardi A, Curnow SJ, Zhan H, Calder VL.

Clin Exp Allergy. 2006 Jun;36(6):777-84.

PMID:
16776679
42.

Th1- and Th2-type cytokines in chronic ocular allergy.

Leonardi A, Fregona IA, Plebani M, Secchi AG, Calder VL.

Graefes Arch Clin Exp Ophthalmol. 2006 Oct;244(10):1240-5. Epub 2006 Mar 15.

PMID:
16538446
43.

Multiplex cytokine detection versus ELISA for aqueous humor: IL-5, IL-10, and IFNgamma profiles in uveitis.

Ooi KG, Galatowicz G, Towler HM, Lightman SL, Calder VL.

Invest Ophthalmol Vis Sci. 2006 Jan;47(1):272-7.

PMID:
16384973
44.

Role of interferon-gamma in a mouse model of allergic conjunctivitis.

Stern ME, Siemasko K, Gao J, Duong A, Beauregard C, Calder V, Niederkorn JY.

Invest Ophthalmol Vis Sci. 2005 Sep;46(9):3239-46.

PMID:
16123425
45.

Suppression of autoimmune retinal disease by lovastatin does not require Th2 cytokine induction.

Harry R, Gegg M, Hankey D, Zambarakji H, Pryce G, Baker D, Calder V, Adamson P, Greenwood J.

J Immunol. 2005 Feb 15;174(4):2327-2335.

46.

Intracellular T lymphocyte cytokine profiles in the aqueous humour of patients with uveitis and correlation with clinical phenotype.

Hill T, Galatowicz G, Akerele T, Lau CH, Calder V, Lightman S.

Clin Exp Immunol. 2005 Jan;139(1):132-7. Erratum in: Clin Exp Immunol. 2005 Apr;140(1):192-3.

47.

Basic science and pathophysiology of ocular allergy.

Calder VL, Lackie PM.

Curr Allergy Asthma Rep. 2004 Jul;4(4):326-31. Review.

PMID:
15175149
48.

The immunomodulatory role of human conjunctival epithelial cells.

Zhan H, Towler HM, Calder VL.

Invest Ophthalmol Vis Sci. 2003 Sep;44(9):3906-10.

PMID:
12939308
49.

T-cell characterization in chronic allergic eye disease.

Zhan H, Calder V, Lightman S.

Curr Allergy Asthma Rep. 2003 Jul;3(4):358-62. Review.

PMID:
12791216
50.

Antigen-specific T-cell downregulation by human dendritic cells following blockade of NF-kappaB.

Calder VL, Bondeson J, Brennan FM, Foxwell BM, Feldmann M.

Scand J Immunol. 2003 Mar;57(3):261-70.

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