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Items: 29


Beta1-adrenoceptor antagonist, metoprolol attenuates cardiac myocyte Ca2+ handling dysfunction in rats with pulmonary artery hypertension.

Fowler ED, Drinkhill MJ, Norman R, Pervolaraki E, Stones R, Steer E, Benoist D, Steele DS, Calaghan SC, White E.

J Mol Cell Cardiol. 2018 Jul;120:74-83. doi: 10.1016/j.yjmcc.2018.05.015. Epub 2018 May 26.


Caveolae in Rabbit Ventricular Myocytes: Distribution and Dynamic Diminution after Cell Isolation.

Burton RAB, Rog-Zielinska EA, Corbett AD, Peyronnet R, Bodi I, Fink M, Sheldon J, Hoenger A, Calaghan SC, Bub G, Kohl P.

Biophys J. 2017 Sep 5;113(5):1047-1059. doi: 10.1016/j.bpj.2017.07.026.


Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance.

Rode B, Shi J, Endesh N, Drinkhill MJ, Webster PJ, Lotteau SJ, Bailey MA, Yuldasheva NY, Ludlow MJ, Cubbon RM, Li J, Futers TS, Morley L, Gaunt HJ, Marszalek K, Viswambharan H, Cuthbertson K, Baxter PD, Foster R, Sukumar P, Weightman A, Calaghan SC, Wheatcroft SB, Kearney MT, Beech DJ.

Nat Commun. 2017 Aug 24;8(1):350. doi: 10.1038/s41467-017-00429-3.


Cellular Hypertrophy and Increased Susceptibility to Spontaneous Calcium-Release of Rat Left Atrial Myocytes Due to Elevated Afterload.

Zhang H, Cannell MB, Kim SJ, Watson JJ, Norman R, Calaghan SC, Orchard CH, James AF.

PLoS One. 2015 Dec 29;10(12):e0144309. doi: 10.1371/journal.pone.0144309. eCollection 2015.


The Golgi apparatus is a functionally distinct Ca2+ store regulated by the PKA and Epac branches of the ╬▓1-adrenergic signaling pathway.

Yang Z, Kirton HM, MacDougall DA, Boyle JP, Deuchars J, Frater B, Ponnambalam S, Hardy ME, White E, Calaghan SC, Peers C, Steele DS.

Sci Signal. 2015 Oct 13;8(398):ra101. doi: 10.1126/scisignal.aaa7677.


Voluntary exercise delays heart failure onset in rats with pulmonary artery hypertension.

Natali AJ, Fowler ED, Calaghan SC, White E.

Am J Physiol Heart Circ Physiol. 2015 Aug 1;309(3):H421-4. doi: 10.1152/ajpheart.00262.2015. Epub 2015 May 22.


Identification of caveolar resident proteins in ventricular myocytes using a quantitative proteomic approach: dynamic changes in caveolar composition following adrenoceptor activation.

Wypijewski KJ, Tinti M, Chen W, Lamont D, Ashford ML, Calaghan SC, Fuller W.

Mol Cell Proteomics. 2015 Mar;14(3):596-608. doi: 10.1074/mcp.M114.038570. Epub 2015 Jan 5.


Substrate recognition by the cell surface palmitoyl transferase DHHC5.

Howie J, Reilly L, Fraser NJ, Vlachaki Walker JM, Wypijewski KJ, Ashford ML, Calaghan SC, McClafferty H, Tian L, Shipston MJ, Boguslavskyi A, Shattock MJ, Fuller W.

Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):17534-9. doi: 10.1073/pnas.1413627111. Epub 2014 Nov 24.


A separate pool of cardiac phospholemman that does not regulate or associate with the sodium pump: multimers of phospholemman in ventricular muscle.

Wypijewski KJ, Howie J, Reilly L, Tulloch LB, Aughton KL, McLatchie LM, Shattock MJ, Calaghan SC, Fuller W.

J Biol Chem. 2013 May 10;288(19):13808-20. doi: 10.1074/jbc.M113.460956. Epub 2013 Mar 26.


Regulation of the cardiac sodium pump.

Fuller W, Tulloch LB, Shattock MJ, Calaghan SC, Howie J, Wypijewski KJ.

Cell Mol Life Sci. 2013 Apr;70(8):1357-80. doi: 10.1007/s00018-012-1134-y. Epub 2012 Sep 7. Review.


Caveolae create local signalling domains through their distinct protein content, lipid profile and morphology.

Harvey RD, Calaghan SC.

J Mol Cell Cardiol. 2012 Feb;52(2):366-75. doi: 10.1016/j.yjmcc.2011.07.007. Epub 2011 Jul 19. Review.


Mechanical Modulation of Intracellular Ion Concentrations: Mechanisms and Electrical Consequences.

Calaghan SC, White E.

In: Kamkin A, Kiseleva I, editors. Mechanosensitivity in Cells and Tissues. Moscow: Academia; 2005.


Effects of cholesterol depletion on compartmentalized cAMP responses in adult cardiac myocytes.

Agarwal SR, MacDougall DA, Tyser R, Pugh SD, Calaghan SC, Harvey RD.

J Mol Cell Cardiol. 2011 Mar;50(3):500-9. doi: 10.1016/j.yjmcc.2010.11.015. Epub 2010 Nov 27.


Store-operated Ca2+ entry in malignant hyperthermia-susceptible human skeletal muscle.

Duke AM, Hopkins PM, Calaghan SC, Halsall JP, Steele DS.

J Biol Chem. 2010 Aug 13;285(33):25645-53. doi: 10.1074/jbc.M110.104976. Epub 2010 Jun 21.


Transmural variations in gene expression of stretch-modulated proteins in the rat left ventricle.

Stones R, Calaghan SC, Billeter R, Harrison SM, White E.

Pflugers Arch. 2007 Jul;454(4):545-9. Epub 2007 Mar 8.


The cellular basis for enhanced volume-modulated cardiac output in fish hearts.

Shiels HA, Calaghan SC, White E.

J Gen Physiol. 2006 Jul;128(1):37-44. Epub 2006 Jun 12.


Compartmentalized signaling in cardiomyocyte lipid domains--do structure and function match up?

Calaghan SC, Taggart MJ.

J Mol Cell Cardiol. 2006 Jul;41(1):1-3. Epub 2006 Jun 12. Review. No abstract available.


Cytoskeletal modulation of electrical and mechanical activity in cardiac myocytes.

Calaghan SC, Le Guennec JY, White E.

Prog Biophys Mol Biol. 2004 Jan;84(1):29-59. Review.


Do stretch-induced changes in intracellular calcium modify the electrical activity of cardiac muscle?

Calaghan SC, Belus A, White E.

Prog Biophys Mol Biol. 2003 May-Jul;82(1-3):81-95. Review.


Cardiac microtubules are more resistant to chemical depolymerisation in streptozotocin-induced diabetes in the rat.

Howarth FC, Qureshi MA, White E, Calaghan SC.

Pflugers Arch. 2002 Jun;444(3):432-7. Epub 2002 Mar 15.


A role for C-protein in the regulation of contraction and intracellular Ca2+ in intact rat ventricular myocytes.

Calaghan SC, Trinick J, Knight PJ, White E.

J Physiol. 2000 Oct 1;528 Pt 1:151-6.


Biphasic effects of hyposmotic challenge on excitation-contraction coupling in rat ventricular myocytes.

Brette F, Calaghan SC, Lappin S, White E, Colyer J, Le Guennec JY.

Am J Physiol Heart Circ Physiol. 2000 Oct;279(4):H1963-71.


The role of calcium in the response of cardiac muscle to stretch.

Calaghan SC, White E.

Prog Biophys Mol Biol. 1999;71(1):59-90. Review.


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