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Items: 1 to 50 of 75

1.

New Insights into ADAMTS Metalloproteases in the Central Nervous System.

Mohamedi Y, Fontanil T, Cobo T, Cal S, Obaya AJ.

Biomolecules. 2020 Mar 5;10(3). pii: E403. doi: 10.3390/biom10030403. Review.

2.

Novel Associations Within the Tumor Microenvironment: Fibulins Meet ADAMTSs.

Fontanil T, Mohamedi Y, Cobo T, Cal S, Obaya ÁJ.

Front Oncol. 2019 Aug 22;9:796. doi: 10.3389/fonc.2019.00796. eCollection 2019. Review.

3.

Antitumor Potential of Fibulin-5 in Breast Cancer Cells Depends on Its RGD Cell Adhesion Motif.

Mohamedi Y, Fontanil T, Cobo T, Vega JA, Cobo JL, Pérez-Basterrechea M, Cobo J, Obaya ÁJ, Cal S.

Cell Physiol Biochem. 2019;53(1):87-100. doi: 10.33594/000000123.

4.

Neurocan is a New Substrate for the ADAMTS12 Metalloprotease: Potential Implications in Neuropathies.

Fontanil T, Mohamedi Y, Moncada-Pazos A, Cobo T, Vega JA, Cobo JL, García-Suárez O, Cobo J, Obaya ÁJ, Cal S.

Cell Physiol Biochem. 2019;52(5):1003-1016. doi: 10.33594/000000069.

5.

Withdrawal: Matriptase-2, a membrane-bound mosaic serine proteinase predominantly expressed in human liver and showing degrading activity against extracellular matrix proteins.

Velasco G, Cal S, Quesada V, Sánchez LM, López-Otín C.

J Biol Chem. 2019 Jan 25;294(4):1430. doi: 10.1074/jbc.W118.007324. No abstract available.

6.

Withdrawal: Identification, characterization, and intracellular processing of ADAM-TS12, a novel human disintegrin with a complex structural organization involving multiple thrombospondin-1 repeats.

Cal S, Argüelles JM, Fernández PL, López-Otín C.

J Biol Chem. 2019 Jan 25;294(4):1429. doi: 10.1074/jbc.W118.007323. No abstract available.

7.

Desertomycin G, a New Antibiotic with Activity against Mycobacterium tuberculosis and Human Breast Tumor Cell Lines Produced by Streptomyces althioticus MSM3, Isolated from the Cantabrian Sea Intertidal Macroalgae Ulva sp.

Braña AF, Sarmiento-Vizcaíno A, Pérez-Victoria I, Martín J, Otero L, Palacios-Gutiérrez JJ, Fernández J, Mohamedi Y, Fontanil T, Salmón M, Cal S, Reyes F, García LA, Bianco G.

Mar Drugs. 2019 Feb 12;17(2). pii: E114. doi: 10.3390/md17020114.

8.

An altered gene expression profile in tyramine-exposed intestinal cell cultures supports the genotoxicity of this biogenic amine at dietary concentrations.

Del Rio B, Redruello B, Ladero V, Cal S, Obaya AJ, Alvarez MA.

Sci Rep. 2018 Nov 19;8(1):17038. doi: 10.1038/s41598-018-35125-9.

9.

Identification and characterization of ADAMTS-20 defines a novel subfamily of metalloproteinases-disintegrins with multiple thrombospondin-1 repeats and a unique GON domain.

Llamazares M, Cal S, Quesada V, López-Otín C.

J Biol Chem. 2018 Jul 27;293(30):11785. doi: 10.1074/jbc.AAC118.004702. No abstract available.

10.

Human polyserase-2, a novel enzyme with three tandem serine protease domains in a single polypeptide chain.

Cal S, Quesada V, Llamazares M, Díaz-Perales A, Garabaya C, López-Otín C.

J Biol Chem. 2018 Jul 27;293(30):11784. doi: 10.1074/jbc.AAC118.004649. No abstract available.

11.

ADAMTS-12 metalloprotease is necessary for normal inflammatory response.

Moncada-Pazos A, Obaya AJ, Llamazares M, Heljasvaara R, Suárez MF, Colado E, Noël A, Cal S, López-Otín C.

J Biol Chem. 2018 Jul 20;293(29):11648. doi: 10.1074/jbc.AAC118.004590. No abstract available.

12.

Assessing the Influence of a Protease in Cell Migration Using the Barrier-Migration Assay.

Fontanil T, Mohamedi Y, Cal S, Obaya ÁJ.

Methods Mol Biol. 2018;1731:133-143. doi: 10.1007/978-1-4939-7595-2_13.

PMID:
29318550
13.

Periostin, dentin matrix protein 1 and P2rx7 ion channel in human teeth and periodontal ligament.

Menéndez-Diaz I, Muriel JD, García-Suárez O, Obaya A, Cal S, Cobo J, Vega JA, Cobo T.

Ann Anat. 2018 Mar;216:103-111. doi: 10.1016/j.aanat.2017.12.004. Epub 2017 Dec 28.

PMID:
29289709
14.

Fibroblasts accelerate islet revascularization and improve long-term graft survival in a mouse model of subcutaneous islet transplantation.

Perez-Basterrechea M, Esteban MM, Alvarez-Viejo M, Fontanil T, Cal S, Sanchez Pitiot M, Otero J, Obaya AJ.

PLoS One. 2017 Jul 3;12(7):e0180695. doi: 10.1371/journal.pone.0180695. eCollection 2017.

15.

Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism.

Krishnaiah SY, Wu G, Altman BJ, Growe J, Rhoades SD, Coldren F, Venkataraman A, Olarerin-George AO, Francey LJ, Mukherjee S, Girish S, Selby CP, Cal S, Er U, Sianati B, Sengupta A, Anafi RC, Kavakli IH, Sancar A, Baur JA, Dang CV, Hogenesch JB, Weljie AM.

Cell Metab. 2017 May 2;25(5):1206. doi: 10.1016/j.cmet.2017.04.023. No abstract available.

16.

Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism.

Krishnaiah SY, Wu G, Altman BJ, Growe J, Rhoades SD, Coldren F, Venkataraman A, Olarerin-George AO, Francey LJ, Mukherjee S, Girish S, Selby CP, Cal S, Er U, Sianati B, Sengupta A, Anafi RC, Kavakli IH, Sancar A, Baur JA, Dang CV, Hogenesch JB, Weljie AM.

Cell Metab. 2017 Apr 4;25(4):961-974.e4. doi: 10.1016/j.cmet.2017.03.019. Erratum in: Cell Metab. 2017 May 2;25(5):1206.

17.

Cleavage of Fibulin-2 by the aggrecanases ADAMTS-4 and ADAMTS-5 contributes to the tumorigenic potential of breast cancer cells.

Fontanil T, Álvarez-Teijeiro S, Villaronga MÁ, Mohamedi Y, Solares L, Moncada-Pazos A, Vega JA, García-Suárez O, Pérez-Basterrechea M, García-Pedrero JM, Obaya AJ, Cal S.

Oncotarget. 2017 Feb 21;8(8):13716-13729. doi: 10.18632/oncotarget.14627.

18.

The Photolyase/Cryptochrome Family of Proteins as DNA Repair Enzymes and Transcriptional Repressors.

Kavakli IH, Baris I, Tardu M, Gül Ş, Öner H, Çal S, Bulut S, Yarparvar D, Berkel Ç, Ustaoğlu P, Aydın C.

Photochem Photobiol. 2017 Jan;93(1):93-103. doi: 10.1111/php.12669. Epub 2017 Jan 9. Review.

PMID:
28067410
19.

Functional Recovery of AQP2 Recessive Mutations Through Hetero-Oligomerization with Wild-Type Counterpart.

El Tarazi A, Lussier Y, Da Cal S, Bissonnette P, Bichet DG.

Sci Rep. 2016 Sep 19;6:33298. doi: 10.1038/srep33298.

20.

A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features.

Adhikari K, Fontanil T, Cal S, Mendoza-Revilla J, Fuentes-Guajardo M, Chacón-Duque JC, Al-Saadi F, Johansson JA, Quinto-Sanchez M, Acuña-Alonzo V, Jaramillo C, Arias W, Barquera Lozano R, Macín Pérez G, Gómez-Valdés J, Villamil-Ramírez H, Hunemeier T, Ramallo V, Silva de Cerqueira CC, Hurtado M, Villegas V, Granja V, Gallo C, Poletti G, Schuler-Faccini L, Salzano FM, Bortolini MC, Canizales-Quinteros S, Rothhammer F, Bedoya G, Gonzalez-José R, Headon D, López-Otín C, Tobin DJ, Balding D, Ruiz-Linares A.

Nat Commun. 2016 Mar 1;7:10815. doi: 10.1038/ncomms10815.

21.

Fibulin-5 downregulates Ki-67 and inhibits proliferation and invasion of breast cancer cells.

Mohamedi Y, Fontanil T, Solares L, Garcia-Suárez O, García-Piqueras J, Vega JA, Cal S, Obaya AJ.

Int J Oncol. 2016 Apr;48(4):1447-56. doi: 10.3892/ijo.2016.3394. Epub 2016 Feb 17.

PMID:
26891749
22.

DESC1, a novel tumor suppressor, sensitizes cells to apoptosis by downregulating the EGFR/AKT pathway in esophageal squamous cell carcinoma.

Ng HY, Ko JM, Yu VZ, Ip JC, Dai W, Cal S, Lung ML.

Int J Cancer. 2016 Jun 15;138(12):2940-51. doi: 10.1002/ijc.30034. Epub 2016 Feb 26.

23.

Role of Periostin in Adhesion and Migration of Bone Remodeling Cells.

Cobo T, Viloria CG, Solares L, Fontanil T, González-Chamorro E, De Carlos F, Cobo J, Cal S, Obaya AJ.

PLoS One. 2016 Jan 25;11(1):e0147837. doi: 10.1371/journal.pone.0147837. eCollection 2016.

24.

Immunohistochemical localization of periostin in human gingiva.

Cobo T, Obaya A, Cal S, Solares L, Cabo R, Vega JA, Cobo J.

Eur J Histochem. 2015 Sep 29;59(3):2548. doi: 10.4081/ejh.2015.2548.

25.

ADAMTS proteases and cancer.

Cal S, López-Otín C.

Matrix Biol. 2015 May-Jul;44-46:77-85. doi: 10.1016/j.matbio.2015.01.013. Epub 2015 Jan 28. Review.

26.

Hypernociceptive responses following the intratibial inoculation of RM1 prostate cancer cells in mice.

Llorián-Salvador M, Pevida M, Fernández-García MT, Lastra A, Obaya A, Cal S, Hidalgo A, Menéndez L, Baamonde A.

Prostate. 2015 Jan;75(1):70-83. doi: 10.1002/pros.22893. Epub 2014 Sep 27.

PMID:
25263196
27.

Polyserase-1/TMPRSS9 induces pro-tumor effects in pancreatic cancer cells by activation of pro-uPA.

Fontanil T, Mohamedi Y, Esteban MM, Obaya AJ, Cal S.

Oncol Rep. 2014 Jun;31(6):2792-6. doi: 10.3892/or.2014.3146. Epub 2014 Apr 23.

PMID:
24756697
28.

Interaction between the ADAMTS-12 metalloprotease and fibulin-2 induces tumor-suppressive effects in breast cancer cells.

Fontanil T, Rúa S, Llamazares M, Moncada-Pazos A, Quirós PM, García-Suárez O, Vega JA, Sasaki T, Mohamedi Y, Esteban MM, Obaya AJ, Cal S.

Oncotarget. 2014 Mar 15;5(5):1253-64.

29.

Cell-cell adhesion genes CTNNA2 and CTNNA3 are tumour suppressors frequently mutated in laryngeal carcinomas.

Fanjul-Fernández M, Quesada V, Cabanillas R, Cadiñanos J, Fontanil T, Obaya A, Ramsay AJ, Llorente JL, Astudillo A, Cal S, López-Otín C.

Nat Commun. 2013;4:2531. doi: 10.1038/ncomms3531.

PMID:
24100690
30.

Resilience in systemic lupus erythematosus.

Cal SF, Santiago MB.

Psychol Health Med. 2013;18(5):558-63. doi: 10.1080/13548506.2013.764457. Epub 2013 Jan 28.

PMID:
23350645
31.

Immune-dependent and independent antitumor activity of GM-CSF aberrantly expressed by mouse and human colorectal tumors.

Urdinguio RG, Fernandez AF, Moncada-Pazos A, Huidobro C, Rodriguez RM, Ferrero C, Martinez-Camblor P, Obaya AJ, Bernal T, Parra-Blanco A, Rodrigo L, Santacana M, Matias-Guiu X, Soldevilla B, Dominguez G, Bonilla F, Cal S, Lopez-Otin C, Fraga MF.

Cancer Res. 2013 Jan 1;73(1):395-405. doi: 10.1158/0008-5472.CAN-12-0806. Epub 2012 Oct 29.

32.

ADAMTS-12 metalloprotease is necessary for normal inflammatory response.

Moncada-Pazos A, Obaya AJ, Llamazares M, Heljasvaara R, Suárez MF, Colado E, Noël A, Cal S, López-Otín C.

J Biol Chem. 2012 Nov 16;287(47):39554-63. doi: 10.1074/jbc.M112.408625. Epub 2012 Sep 27. Erratum in: J Biol Chem. 2018 Jul 20;293(29):11648.

33.

New and paradoxical roles of matrix metalloproteinases in the tumor microenvironment.

Noël A, Gutiérrez-Fernández A, Sounni NE, Behrendt N, Maquoi E, Lund IK, Cal S, Hoyer-Hansen G, López-Otín C.

Front Pharmacol. 2012 Jul 17;3:140. doi: 10.3389/fphar.2012.00140. eCollection 2012.

34.

The dual role of fibulins in tumorigenesis.

Obaya AJ, Rua S, Moncada-Pazos A, Cal S.

Cancer Lett. 2012 Dec 28;325(2):132-8. doi: 10.1016/j.canlet.2012.06.019. Epub 2012 Jul 7.

PMID:
22781395
35.

Analysis of the disintegrin-metalloproteinases family reveals ADAM29 and ADAM7 are often mutated in melanoma.

Wei X, Moncada-Pazos A, Cal S, Soria-Valles C, Gartner J, Rudloff U, Lin JC; NISC Comparative Sequencing Program, Rosenberg SA, López-Otín C, Samuels Y.

Hum Mutat. 2011 Jun;32(6):E2148-75. doi: 10.1002/humu.21477. Epub 2011 Feb 24.

36.

The nutraceutical flavonoid luteolin inhibits ADAMTS-4 and ADAMTS-5 aggrecanase activities.

Moncada-Pazos A, Obaya AJ, Viloria CG, López-Otín C, Cal S.

J Mol Med (Berl). 2011 Jun;89(6):611-9. doi: 10.1007/s00109-011-0741-7. Epub 2011 Mar 2.

PMID:
21365186
37.

[Application of microfluidic chips in cellular microenvironment].

Lu S, Cal S, Jiang J.

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2010 Jun;27(3):675-9. Review. Chinese.

PMID:
20649042
38.

Higher sensitivity of Adamts12-deficient mice to tumor growth and angiogenesis.

El Hour M, Moncada-Pazos A, Blacher S, Masset A, Cal S, Berndt S, Detilleux J, Host L, Obaya AJ, Maillard C, Foidart JM, Ectors F, Noel A, Lopez-Otin C.

Oncogene. 2010 May 20;29(20):3025-32. doi: 10.1038/onc.2010.49. Epub 2010 Mar 8.

39.

The ADAMTS12 metalloprotease gene is epigenetically silenced in tumor cells and transcriptionally activated in the stroma during progression of colon cancer.

Moncada-Pazos A, Obaya AJ, Fraga MF, Viloria CG, Capellá G, Gausachs M, Esteller M, López-Otín C, Cal S.

J Cell Sci. 2009 Aug 15;122(Pt 16):2906-13. doi: 10.1242/jcs.050468. Epub 2009 Jul 28.

40.

Genetic inactivation of ADAMTS15 metalloprotease in human colorectal cancer.

Viloria CG, Obaya AJ, Moncada-Pazos A, Llamazares M, Astudillo A, Capellá G, Cal S, López-Otín C.

Cancer Res. 2009 Jun 1;69(11):4926-34. doi: 10.1158/0008-5472.CAN-08-4155. Epub 2009 May 19.

41.

SMIT2 mediates all myo-inositol uptake in apical membranes of rat small intestine.

Aouameur R, Da Cal S, Bissonnette P, Coady MJ, Lapointe JY.

Am J Physiol Gastrointest Liver Physiol. 2007 Dec;293(6):G1300-7. Epub 2007 Oct 11.

42.

The ADAMTS12 metalloproteinase exhibits anti-tumorigenic properties through modulation of the Ras-dependent ERK signalling pathway.

Llamazares M, Obaya AJ, Moncada-Pazos A, Heljasvaara R, Espada J, López-Otín C, Cal S.

J Cell Sci. 2007 Oct 15;120(Pt 20):3544-52. Epub 2007 Sep 25.

43.

Human DESC1 serine protease confers tumorigenic properties to MDCK cells and it is upregulated in tumours of different origin.

Viloria CG, Peinado JR, Astudillo A, García-Suárez O, González MV, Suárez C, Cal S.

Br J Cancer. 2007 Jul 16;97(2):201-9. Epub 2007 Jun 19.

44.

Expanding the complexity of the human degradome: polyserases and their tandem serine protease domains.

Cal S, Moncada-Pazos A, Lopez-Otin C.

Front Biosci. 2007 May 1;12:4661-9. Review.

PMID:
17485402
45.

Molecular characterization of a t(9;12)(p21;q13) balanced chromosome translocation in combination with integrative genomics analysis identifies C9orf14 as a candidate tumor-suppressor.

Pujana MA, Ruiz A, Badenas C, Puig-Butille JA, Nadal M, Stark M, Gómez L, Valls J, Solé X, Hernández P, Cerrato C, Madrigal I, de Cid R, Aguilar H, Capellá G, Cal S, James MR, Walker GJ, Malvehy J, Milà M, Hayward NK, Estivill X, Puig S.

Genes Chromosomes Cancer. 2007 Feb;46(2):155-62.

PMID:
17099875
46.

The prevalence of anemia in adolescents: a study from Turkey.

Kara B, Cal S, Aydoğan A, Sarper N.

J Pediatr Hematol Oncol. 2006 May;28(5):316-21.

PMID:
16772884
47.

A functional link between the tumour suppressors ARF and p33ING1.

González L, Freije JM, Cal S, López-Otín C, Serrano M, Palmero I.

Oncogene. 2006 Aug 24;25(37):5173-9. Epub 2006 Apr 10.

PMID:
16607280
48.

Identification and characterization of human polyserase-3, a novel protein with tandem serine-protease domains in the same polypeptide chain.

Cal S, Peinado JR, Llamazares M, Quesada V, Moncada-Pazos A, Garabaya C, López-Otín C.

BMC Biochem. 2006 Mar 27;7:9.

49.

Recombinant CUB-1 domain polypeptide inhibits the cleavage of ULVWF strings by ADAMTS13 under flow conditions.

Tao Z, Peng Y, Nolasco L, Cal S, Lopez-Otin C, Li R, Moake JL, López JA, Dong JF.

Blood. 2005 Dec 15;106(13):4139-45. Epub 2005 Sep 1.

50.

[Evaluation of a pharmaceutical care program to improve adherence to antiretroviral therapy].

Codina Jané C, Tuset Creus M, Ibarra Barrueta O, Delgado Sánchez O, Morancho Echevarría O, García Díaz B, Escobar A, Martínez B, Butiñá T, Amador P, Estaún E, Sáinz A, Martínez N, Cal S, Gómez MR, López RM, Carmona A, Jiménez I, Moriel C, León J, Iranzo MD, Caro L, Castillo I, Bachiller P, Irastorza B, Gine M, Sala ML, Requena T, Santolaya R, Lluch A, Iruin A, Alfaro J; Grupo VIH de la SEFH.

Farm Hosp. 2004;28(6 Suppl 1):19-26. Spanish.

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