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Items: 1 to 50 of 67

1.

NIST Interlaboratory Study on Glycosylation Analysis of Monoclonal Antibodies: Comparison of Results from Diverse Analytical Methods.

De Leoz MLA, Duewer DL, Fung A, Liu L, Yau HK, Potter O, Staples GO, Furuki K, Frenkel R, Hu Y, Sosic Z, Zhang P, Altmann F, Gruber C, Shao C, Zaia J, Evers W, Pangelley S, Suckau D, Wiechmann A, Resemann A, Jabs W, Beck A, Froehlich JW, Huang C, Li Y, Liu Y, Sun S, Wang Y, Seo Y, An HJ, Reichardt NC, Ruiz JE, Archer-Hartmann S, Azadi P, Bell L, Lakos Z, An Y, Cipollo JF, Pučić-Baković M, Štambuk J, Lauc G, Li X, Wang PG, Bock A, Hennig R, Rapp E, Creskey M, Cyr T, Nakano M, Sugiyama T, Leung PA, Link-Lenczowski P, Jaworek J, Yang SJ, Zhang H, Kelly T, Klapoetke S, Cao R, Kim JY, Lee HK, Lee J, Yoo JS, Kim SR, Suh SK, de Haan N, Falck D, Lageveen-Kammeijer GSM, Wuhrer M, Emery RJ, Kozak RP, Liew LP, Royle L, Urbanowicz PA, Packer N, Song X, Everest-Dass A, Lattová E, Cajic S, Alagesan K, Kolarich D, Kasali T, Lindo V, Chen Y, Goswami K, Gau B, Amunugama R, Jones R, Stroop CJM, Kato K, Yagi H, Kondo S, Yuen CT, Harazono A, Shi X, Magnelli P, Kasper BT, Mahal LK, Harvey DJ, O'Flaherty RM, Rudd P, Saldova R, Hecht ES, Muddiman DC, Kang J, Bhoskar P, Menard D, Saati A, Merle C, Mast S, Tep S, Truong J, Nishikaze T, Sekiya S, Shafer A, Funaoka S, Toyoda M, de Vreugd P, Caron C, Pradhan P, Tan NC, Mechref Y, Patil S, Rohrer JS, Chakrabarti R, Dadke D, Lahori M, Zou C, Cairo CW, Reiz B, Whittal RM, Lebrilla C, Wu LD, Guttman A, Szigeti M, Kremkow BG, Lee K, Sihlbom C, Adamczyk B, Jin C, Karlsson NG, Örnros J, Larson G, Nilsson J, Meyer B, Wiegandt A, Komatsu E, Perreault H, Bodnar ED, Said N, Francois YN, Leize-Wagner E, Maier S, Zeck A, Heck AJR, Yang Y, Haselberg R, Yu YQ, Alley W, Leone JW, Yuan H, Stein SE.

Mol Cell Proteomics. 2019 Oct 7. pii: mcp.RA119.001677. doi: 10.1074/mcp.RA119.001677. [Epub ahead of print]

2.

A quantitative, high-throughput method identifies protein-glycan interactions via mass spectrometry.

Kitov PI, Kitova EN, Han L, Li Z, Jung J, Rodrigues E, Hunter CD, Cairo CW, Macauley MS, Klassen JS.

Commun Biol. 2019 Jul 22;2:268. doi: 10.1038/s42003-019-0507-2. eCollection 2019.

3.

Crystal structures of human lysosomal EPDR1 reveal homology with the superfamily of bacterial lipoprotein transporters.

Wei Y, Xiong ZJ, Li J, Zou C, Cairo CW, Klassen JS, Privé GG.

Commun Biol. 2019 Feb 5;2:52. doi: 10.1038/s42003-018-0262-9. eCollection 2019.

4.

Persistent reduction in sialylation of cerebral glycoproteins following postnatal inflammatory exposure.

Demina EP, Pierre WC, Nguyen ALA, Londono I, Reiz B, Zou C, Chakraberty R, Cairo CW, Pshezhetsky AV, Lodygensky GA.

J Neuroinflammation. 2018 Dec 5;15(1):336. doi: 10.1186/s12974-018-1367-2.

5.

Selective Inhibitors of Human Neuraminidase 1 (NEU1).

Guo T, Héon-Roberts R, Zou C, Zheng R, Pshezhetsky AV, Cairo CW.

J Med Chem. 2018 Dec 27;61(24):11261-11279. doi: 10.1021/acs.jmedchem.8b01411. Epub 2018 Dec 5.

PMID:
30457869
6.

A tyrosine sulfation-dependent HLA-I modification identifies memory B cells and plasma cells.

Chan JTH, Liu Y, Khan S, St-Germain JR, Zou C, Leung LYT, Yang J, Shi M, Grunebaum E, Campisi P, Propst EJ, Holler T, Bar-Or A, Wither JE, Cairo CW, Moran MF, Palazzo AF, Cooper MD, Ehrhardt GRA.

Sci Adv. 2018 Nov 7;4(11):eaar7653. doi: 10.1126/sciadv.aar7653. eCollection 2018 Nov.

7.

Synthetic Strategies for Modified Glycosphingolipids and Their Design as Probes.

Hunter CD, Guo T, Daskhan G, Richards MR, Cairo CW.

Chem Rev. 2018 Sep 12;118(17):8188-8241. doi: 10.1021/acs.chemrev.8b00070. Epub 2018 Jul 6. Review.

PMID:
29979587
8.

Molecular dynamics simulations of viral neuraminidase inhibitors with the human neuraminidase enzymes: Insights into isoenzyme selectivity.

Richards MR, Guo T, Hunter CD, Cairo CW.

Bioorg Med Chem. 2018 Oct 15;26(19):5349-5358. doi: 10.1016/j.bmc.2018.05.035. Epub 2018 May 23.

PMID:
29903413
9.

Neuraminidase 1 activates insulin receptor and reverses insulin resistance in obese mice.

Fougerat A, Pan X, Smutova V, Heveker N, Cairo CW, Issad T, Larrivée B, Medin JA, Pshezhetsky AV.

Mol Metab. 2018 Jun;12:76-88. doi: 10.1016/j.molmet.2018.03.017. Epub 2018 Apr 21.

10.

Selective Inhibitors of Human Neuraminidase 3.

Guo T, Dätwyler P, Demina E, Richards MR, Ge P, Zou C, Zheng R, Fougerat A, Pshezhetsky AV, Ernst B, Cairo CW.

J Med Chem. 2018 Mar 8;61(5):1990-2008. doi: 10.1021/acs.jmedchem.7b01574. Epub 2018 Feb 21.

PMID:
29425031
11.

Human Neuraminidase Isoenzymes Show Variable Activities for 9- O-Acetyl-sialoside Substrates.

Hunter CD, Khanna N, Richards MR, Rezaei Darestani R, Zou C, Klassen JS, Cairo CW.

ACS Chem Biol. 2018 Apr 20;13(4):922-932. doi: 10.1021/acschembio.7b00952. Epub 2018 Feb 13.

PMID:
29341588
12.

Construction of Multivalent Homo- and Heterofunctional ABO Blood Group Glycoconjugates Using a Trifunctional Linker Strategy.

Daskhan GC, Tran HT, Meloncelli PJ, Lowary TL, West LJ, Cairo CW.

Bioconjug Chem. 2018 Feb 21;29(2):343-362. doi: 10.1021/acs.bioconjchem.7b00679. Epub 2018 Jan 11.

PMID:
29237123
13.

Galectin-3 alters the lateral mobility and clustering of β1-integrin receptors.

Yang EH, Rode J, Howlader MA, Eckermann M, Santos JT, Hernandez Armada D, Zheng R, Zou C, Cairo CW.

PLoS One. 2017 Oct 10;12(10):e0184378. doi: 10.1371/journal.pone.0184378. eCollection 2017.

14.

New Answers to Old Conundrums: What Antibodies, Exosomes and Inflammasomes Bring to the Conversation. Canadian National Transplant Research Program International Summit Report.

Dieudé M, West LJ, Muruve DA, Gunaratnam L, Mohanakumar T, Zorn E, Cairo CW, Freed DH, Schultz KR, Fairchild RL, Hébert MJ.

Transplantation. 2018 Feb;102(2):209-214. doi: 10.1097/TP.0000000000001872. Review. Erratum in: Transplantation. 2018 Jul;102(7):e360. Gunaratman, Lakshman [corrected to Gunaratnam, Lakshman].

15.

Integrin-mediated cell migration is blocked by inhibitors of human neuraminidase.

Jia F, Howlader MA, Cairo CW.

Biochim Biophys Acta. 2016 Sep;1861(9 Pt A):1170-1179. doi: 10.1016/j.bbalip.2016.06.013. Epub 2016 Jun 22.

PMID:
27344026
16.

Screening Glycolipids Against Proteins in Vitro Using Picodiscs and Catch-and-Release Electrospray Ionization-Mass Spectrometry.

Li J, Fan X, Kitova EN, Zou C, Cairo CW, Eugenio L, Ng KK, Xiong ZJ, Privé GG, Klassen JS.

Anal Chem. 2016 May 3;88(9):4742-50. doi: 10.1021/acs.analchem.6b00043. Epub 2016 Apr 20.

PMID:
27049760
17.

Conjugation of A and B Blood Group Structures to Silica Microparticles for the Detection of Antigen-Specific B Cells.

Slaney AM, Dijke IE, Jeyakanthan M, Li C, Zou L, Plaza-Alexander P, Meloncelli PJ, Bau JA, Allan LL, Lowary TL, West LJ, Cairo CW, Buriak JM.

Bioconjug Chem. 2016 Mar 16;27(3):705-15. doi: 10.1021/acs.bioconjchem.5b00672. Epub 2016 Feb 11.

PMID:
26816334
18.

ABH-Glycan Microarray Characterizes ABO Subtype Antibodies: Fine Specificity of Immune Tolerance After ABO-Incompatible Transplantation.

Jeyakanthan M, Meloncelli PJ, Zou L, Lowary TL, Larsen I, Maier S, Tao K, Rusch J, Chinnock R, Shaw N, Burch M, Beddows K, Addonizio L, Zuckerman W, Pahl E, Rutledge J, Kanter KR, Cairo CW, Buriak JM, Ross D, Rebeyka I, West LJ.

Am J Transplant. 2016 May;16(5):1548-58. doi: 10.1111/ajt.13625. Epub 2016 Jan 25.

19.

Enhanced Cross-Linking of Diazirine-Modified Sialylated Glycoproteins Enabled through Profiling of Sialidase Specificities.

McCombs JE, Zou C, Parker RB, Cairo CW, Kohler JJ.

ACS Chem Biol. 2016 Jan 15;11(1):185-92. doi: 10.1021/acschembio.5b00775. Epub 2015 Nov 16.

20.

Detection of Diffusion Heterogeneity in Single Particle Tracking Trajectories Using a Hidden Markov Model with Measurement Noise Propagation.

Slator PJ, Cairo CW, Burroughs NJ.

PLoS One. 2015 Oct 16;10(10):e0140759. doi: 10.1371/journal.pone.0140759. eCollection 2015.

21.

Protecting group-free immobilization of glycans for affinity chromatography using glycosylsulfonohydrazide donors.

Hernandez Armada D, Santos JT, Richards MR, Cairo CW.

Carbohydr Res. 2015 Nov 19;417:109-16. doi: 10.1016/j.carres.2015.09.005. Epub 2015 Sep 16.

PMID:
26454791
22.

Picodiscs for facile protein-glycolipid interaction analysis.

Leney AC, Rezaei Darestani R, Li J, Nikjah S, Kitova EN, Zou C, Cairo CW, Xiong ZJ, Privé GG, Klassen JS.

Anal Chem. 2015 Apr 21;87(8):4402-8. doi: 10.1021/acs.analchem.5b00170. Epub 2015 Apr 9.

PMID:
25803566
23.

A FRET probe for cell-based imaging of ganglioside-processing enzyme activity and high-throughput screening.

Yang GY, Li C, Fischer M, Cairo CW, Feng Y, Withers SG.

Angew Chem Int Ed Engl. 2015 Apr 27;54(18):5389-93. doi: 10.1002/anie.201411747. Epub 2015 Mar 10.

PMID:
25757223
24.

Mapping substrate interactions of the human membrane-associated neuraminidase, NEU3, using STD NMR.

Albohy A, Richards MR, Cairo CW.

Glycobiology. 2015 Mar;25(3):284-93. doi: 10.1093/glycob/cwu109. Epub 2014 Oct 6.

PMID:
25294388
25.

Structural basis for substrate specificity of mammalian neuraminidases.

Smutova V, Albohy A, Pan X, Korchagina E, Miyagi T, Bovin N, Cairo CW, Pshezhetsky AV.

PLoS One. 2014 Sep 15;9(9):e106320. doi: 10.1371/journal.pone.0106320. eCollection 2014.

26.

Sialidase NEU4 is involved in glioblastoma stem cell survival.

Silvestri I, Testa F, Zappasodi R, Cairo CW, Zhang Y, Lupo B, Galli R, Di Nicola M, Venerando B, Tringali C.

Cell Death Dis. 2014 Aug 21;5:e1381. doi: 10.1038/cddis.2014.349.

27.

Identification of Selective Nanomolar Inhibitors of the Human Neuraminidase, NEU4.

Albohy A, Zhang Y, Smutova V, Pshezhetsky AV, Cairo CW.

ACS Med Chem Lett. 2013 May 7;4(6):532-7. doi: 10.1021/ml400080t. eCollection 2013 Jun 13.

28.

Practical labeling methodology for choline-derived lipids and applications in live cell fluorescence imaging.

Li C, Key JA, Jia F, Dandapat A, Hur S, Cairo CW.

Photochem Photobiol. 2014 May-Jun;90(3):686-95. doi: 10.1111/php.12234. Epub 2014 Jan 31.

PMID:
24383866
29.

Mycobacterial phenolic glycolipids with a simplified lipid aglycone modulate cytokine levels through Toll-like receptor 2.

Elsaidi HR, Barreda DR, Cairo CW, Lowary TL.

Chembiochem. 2013 Nov 4;14(16):2153-9. doi: 10.1002/cbic.201300505. Epub 2013 Oct 2.

PMID:
24115598
30.

α-Bromophosphonate analogs of glucose-6-phosphate are inhibitors of glucose-6-phosphatase.

Downey AM, Cairo CW.

Carbohydr Res. 2013 Nov 15;381:123-32. doi: 10.1016/j.carres.2013.08.003. Epub 2013 Aug 11.

PMID:
24095944
31.

Interlaboratory study on differential analysis of protein glycosylation by mass spectrometry: the ABRF glycoprotein research multi-institutional study 2012.

Leymarie N, Griffin PJ, Jonscher K, Kolarich D, Orlando R, McComb M, Zaia J, Aguilan J, Alley WR, Altmann F, Ball LE, Basumallick L, Bazemore-Walker CR, Behnken H, Blank MA, Brown KJ, Bunz SC, Cairo CW, Cipollo JF, Daneshfar R, Desaire H, Drake RR, Go EP, Goldman R, Gruber C, Halim A, Hathout Y, Hensbergen PJ, Horn DM, Hurum D, Jabs W, Larson G, Ly M, Mann BF, Marx K, Mechref Y, Meyer B, Möginger U, Neusüβ C, Nilsson J, Novotny MV, Nyalwidhe JO, Packer NH, Pompach P, Reiz B, Resemann A, Rohrer JS, Ruthenbeck A, Sanda M, Schulz JM, Schweiger-Hufnagel U, Sihlbom C, Song E, Staples GO, Suckau D, Tang H, Thaysen-Andersen M, Viner RI, An Y, Valmu L, Wada Y, Watson M, Windwarder M, Whittal R, Wuhrer M, Zhu Y, Zou C.

Mol Cell Proteomics. 2013 Oct;12(10):2935-51. doi: 10.1074/mcp.M113.030643. Epub 2013 Jun 13.

32.

Glycoform remodeling generates a synthetic T cell phenotype.

Zou C, Loka RS, Zhang Y, Cairo CW.

Bioconjug Chem. 2013 Jun 19;24(6):907-14. doi: 10.1021/bc300599w. Epub 2013 Jun 6.

PMID:
23742724
33.

Identification of selective inhibitors for human neuraminidase isoenzymes using C4,C7-modified 2-deoxy-2,3-didehydro-N-acetylneuraminic acid (DANA) analogues.

Zhang Y, Albohy A, Zou Y, Smutova V, Pshezhetsky AV, Cairo CW.

J Med Chem. 2013 Apr 11;56(7):2948-58. doi: 10.1021/jm301892f. Epub 2013 Mar 26.

PMID:
23530623
34.

Positive regulation of insulin signaling by neuraminidase 1.

Dridi L, Seyrantepe V, Fougerat A, Pan X, Bonneil E, Thibault P, Moreau A, Mitchell GA, Heveker N, Cairo CW, Issad T, Hinek A, Pshezhetsky AV.

Diabetes. 2013 Jul;62(7):2338-46. doi: 10.2337/db12-1825. Epub 2013 Mar 21.

35.

1-[1-(2,1,3-Benzoxadiazol-5-ylmeth-yl)-1H-1,2,3-triazol-4-yl]hexan-1-one.

Key JA, Cairo CW, McDonald R.

Acta Crystallogr Sect E Struct Rep Online. 2012 Nov 1;68(Pt 11):o3132. doi: 10.1107/S1600536812041839. Epub 2012 Oct 13.

36.

5-(1-Benzyl-1H-1,2,3-triazol-4-yl)-2,1,3-benzoxadiazole.

Key JA, Cairo CW, McDonald R.

Acta Crystallogr Sect E Struct Rep Online. 2012 Nov 1;68(Pt 11):o3130-1. doi: 10.1107/S1600536812041827. Epub 2012 Oct 13.

37.

5-(4-Hexyl-1H-1,2,3-triazol-1-yl)-2,1,3-benzoxadiazole.

Key JA, Cairo CW, Ferguson MJ.

Acta Crystallogr Sect E Struct Rep Online. 2012 Nov 1;68(Pt 11):o3128-9. doi: 10.1107/S1600536812041815. Epub 2012 Oct 13.

38.

Protein-glycosphingolipid interactions revealed using catch-and-release mass spectrometry.

Zhang Y, Liu L, Daneshfar R, Kitova EN, Li C, Jia F, Cairo CW, Klassen JS.

Anal Chem. 2012 Sep 18;84(18):7618-21. doi: 10.1021/ac3023857. Epub 2012 Sep 4.

PMID:
22920193
39.

Detection of cellular sialic acid content using nitrobenzoxadiazole carbonyl-reactive chromophores.

Key JA, Li C, Cairo CW.

Bioconjug Chem. 2012 Mar 21;23(3):363-71. doi: 10.1021/bc200276k. Epub 2012 Feb 21.

PMID:
22288945
40.

Substituted benzoxadiazoles as fluorogenic probes: a computational study of absorption and fluorescence.

Brown A, Ngai TY, Barnes MA, Key JA, Cairo CW.

J Phys Chem A. 2012 Jan 12;116(1):46-54. doi: 10.1021/jp2079296. Epub 2011 Dec 22.

PMID:
22136610
41.

Substrate recognition of the membrane-associated sialidase NEU3 requires a hydrophobic aglycone.

Sandbhor MS, Soya N, Albohy A, Zheng RB, Cartmell J, Bundle DR, Klassen JS, Cairo CW.

Biochemistry. 2011 Aug 16;50(32):6753-62. doi: 10.1021/bi200449j.

PMID:
21675735
42.

Inhibitor selectivity of a new class of oseltamivir analogs against viral neuraminidase over human neuraminidase enzymes.

Albohy A, Mohan S, Zheng RB, Pinto BM, Cairo CW.

Bioorg Med Chem. 2011 May 1;19(9):2817-22. doi: 10.1016/j.bmc.2011.03.039. Epub 2011 Mar 23.

PMID:
21489803
43.

Analysis of molecular diffusion by first-passage time variance identifies the size of confinement zones.

Rajani V, Carrero G, Golan DE, de Vries G, Cairo CW.

Biophys J. 2011 Mar 16;100(6):1463-72. doi: 10.1016/j.bpj.2011.01.064.

44.

A protected l-bromophosphonomethylphenylalanine amino acid derivative (BrPmp) for synthesis of irreversible protein tyrosine phosphatase inhibitors.

Tulsi NS, Downey AM, Cairo CW.

Bioorg Med Chem. 2010 Dec 15;18(24):8679-86. doi: 10.1016/j.bmc.2010.09.040. Epub 2010 Sep 29.

PMID:
21055952
45.

Inhibition of human neuraminidase 3 (NEU3) by C9-triazole derivatives of 2,3-didehydro-N-acetyl-neuraminic acid.

Zou Y, Albohy A, Sandbhor M, Cairo CW.

Bioorg Med Chem Lett. 2010 Dec 15;20(24):7529-33. doi: 10.1016/j.bmcl.2010.09.111. Epub 2010 Sep 29.

PMID:
21036040
46.

Immobilization of carbohydrate epitopes for surface plasmon resonance using the Staudinger ligation.

Loka RS, Cairo CW.

Carbohydr Res. 2010 Dec 10;345(18):2641-7. doi: 10.1016/j.carres.2010.09.020. Epub 2010 Sep 21.

PMID:
20971453
47.

Conjugation of synthetic N-acetyl-lactosamine to azide-containing proteins using the Staudinger ligation.

Loka RS, Sadek CM, Romaniuk NA, Cairo CW.

Bioconjug Chem. 2010 Oct 20;21(10):1842-9. doi: 10.1021/bc100209r.

PMID:
20845977
48.

A monomeric photoconvertible fluorescent protein for imaging of dynamic protein localization.

Hoi H, Shaner NC, Davidson MW, Cairo CW, Wang J, Campbell RE.

J Mol Biol. 2010 Sep 3;401(5):776-91. doi: 10.1016/j.jmb.2010.06.056. Epub 2010 Jul 13.

PMID:
20603133
49.

Insight into substrate recognition and catalysis by the human neuraminidase 3 (NEU3) through molecular modeling and site-directed mutagenesis.

Albohy A, Li MD, Zheng RB, Zou C, Cairo CW.

Glycobiology. 2010 Sep;20(9):1127-38. doi: 10.1093/glycob/cwq077. Epub 2010 May 28.

PMID:
20511247
50.

Dynamic regulation of CD45 lateral mobility by the spectrin-ankyrin cytoskeleton of T cells.

Cairo CW, Das R, Albohy A, Baca QJ, Pradhan D, Morrow JS, Coombs D, Golan DE.

J Biol Chem. 2010 Apr 9;285(15):11392-401. doi: 10.1074/jbc.M109.075648. Epub 2010 Feb 17.

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