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Items: 14

1.

Gene Therapy Corrects Brain and Behavioral Pathologies in CLN6-Batten Disease.

Cain JT, Likhite S, White KA, Timm DJ, Davis SS, Johnson TB, Dennys-Rivers CN, Rinaldi F, Motti D, Corcoran S, Morales P, Pierson C, Hughes SM, Lee SY, Kaspar BK, Meyer K, Weimer JM.

Mol Ther. 2019 Oct 2;27(10):1836-1847. doi: 10.1016/j.ymthe.2019.06.015. Epub 2019 Jul 10.

2.

Therapeutic landscape for Batten disease: current treatments and future prospects.

Johnson TB, Cain JT, White KA, Ramirez-Montealegre D, Pearce DA, Weimer JM.

Nat Rev Neurol. 2019 Mar;15(3):161-178. doi: 10.1038/s41582-019-0138-8. Review.

3.

Tracking sex-dependent differences in a mouse model of CLN6-Batten disease.

Poppens MJ, Cain JT, Johnson TB, White KA, Davis SS, Laufmann R, Kloth AD, Weimer JM.

Orphanet J Rare Dis. 2019 Jan 21;14(1):19. doi: 10.1186/s13023-019-0994-8.

4.

Characterization of a recurrent missense mutation in the forkhead DNA-binding domain of FOXP1.

Johnson TB, Mechels K, Anderson RE, Cain JT, Sturdevant DA, Braddock S, Pinz H, Wilson MA, Landsverk M, Roux KJ, Weimer JM.

Sci Rep. 2018 Nov 1;8(1):16161. doi: 10.1038/s41598-018-34437-0.

5.

Cancer exosomes induce tumor innervation.

Madeo M, Colbert PL, Vermeer DW, Lucido CT, Cain JT, Vichaya EG, Grossberg AJ, Muirhead D, Rickel AP, Hong Z, Zhao J, Weimer JM, Spanos WC, Lee JH, Dantzer R, Vermeer PD.

Nat Commun. 2018 Oct 16;9(1):4284. doi: 10.1038/s41467-018-06640-0.

6.

MARCKS regulates neuritogenesis and interacts with a CDC42 signaling network.

Brudvig JJ, Cain JT, Sears RM, Schmidt-Grimminger GG, Wittchen ES, Adler KB, Ghashghaei HT, Weimer JM.

Sci Rep. 2018 Sep 5;8(1):13278. doi: 10.1038/s41598-018-31578-0.

7.

Searching for novel biomarkers using a mouse model of CLN3-Batten disease.

Timm D, Cain JT, Geraets RD, White KA, Koh SY, Kielian T, Pearce DA, Hastings ML, Weimer JM.

PLoS One. 2018 Aug 7;13(8):e0201470. doi: 10.1371/journal.pone.0201470. eCollection 2018.

8.

A porcine model of neurofibromatosis type 1 that mimics the human disease.

White KA, Swier VJ, Cain JT, Kohlmeyer JL, Meyerholz DK, Tanas MR, Uthoff J, Hammond E, Li H, Rohret FA, Goeken A, Chan CH, Leidinger MR, Umesalma S, Wallace MR, Dodd RD, Panzer K, Tang AH, Darbro BW, Moutal A, Cai S, Li W, Bellampalli SS, Khanna R, Rogers CS, Sieren JC, Quelle DE, Weimer JM.

JCI Insight. 2018 Jun 21;3(12). pii: 120402. doi: 10.1172/jci.insight.120402. eCollection 2018 Jun 21.

9.

MARCKS Is Necessary for Netrin-DCC Signaling and Corpus Callosum Formation.

Brudvig JJ, Cain JT, Schmidt-Grimminger GG, Stumpo DJ, Roux KJ, Blackshear PJ, Weimer JM.

Mol Neurobiol. 2018 Nov;55(11):8388-8402. doi: 10.1007/s12035-018-0990-3. Epub 2018 Mar 15.

PMID:
29546593
10.

A tailored mouse model of CLN2 disease: A nonsense mutant for testing personalized therapies.

Geraets RD, Langin LM, Cain JT, Parker CM, Beraldi R, Kovacs AD, Weimer JM, Pearce DA.

PLoS One. 2017 May 2;12(5):e0176526. doi: 10.1371/journal.pone.0176526. eCollection 2017.

11.

Nonsense pathogenic variants in exon 1 of PHOX2B lead to translational reinitiation in congenital central hypoventilation syndrome.

Cain JT, Kim DI, Quast M, Shivega WG, Patrick RJ, Moser C, Reuter S, Perez M, Myers A, Weimer JM, Roux KJ, Landsverk M.

Am J Med Genet A. 2017 May;173(5):1200-1207. doi: 10.1002/ajmg.a.38162. Epub 2017 Mar 29.

12.

Shifts in the vascular endothelial growth factor isoforms result in transcriptome changes correlated with early neural stem cell proliferation and differentiation in mouse forebrain.

Cain JT, Berosik MA, Snyder SD, Crawford NF, Nour SI, Schaubhut GJ, Darland DC.

Dev Neurobiol. 2014 Jan;74(1):63-81. doi: 10.1002/dneu.22130. Epub 2013 Nov 4.

13.

Vascular endothelial growth factor (VEGF) isoform regulation of early forebrain development.

Darland DC, Cain JT, Berosik MA, Saint-Geniez M, Odens PW, Schaubhut GJ, Frisch S, Stemmer-Rachamimov A, Darland T, D'Amore PA.

Dev Biol. 2011 Oct 1;358(1):9-22. doi: 10.1016/j.ydbio.2011.06.045. Epub 2011 Jul 26.

14.

The orgone energy accumulator: believe it or not.

CAIN JT.

Antibiot Chemother (Northfield). 1956 Apr;6(4):255-7. No abstract available.

PMID:
24543955

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