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Items: 12


An unusual presentation of purine nucleoside phosphorylase deficiency mimicking systemic juvenile idiopathic arthritis complicated by macrophage activation syndrome.

Arduini A, Marasco E, Marucci G, Pardeo M, Insalaco A, Caiello I, Moneta GM, Prencipe G, De Benedetti F, Bracaglia C.

Pediatr Rheumatol Online J. 2019 May 22;17(1):25. doi: 10.1186/s12969-019-0328-3.


Variable Clinical Phenotypes and Relation of Interferon Signature with Disease Activity in ADA2 Deficiency.

Insalaco A, Moneta GM, Pardeo M, Caiello I, Messia V, Bracaglia C, Passarelli C, De Benedetti F.

J Rheumatol. 2019 May;46(5):523-526. doi: 10.3899/jrheum.180045. Epub 2019 Jan 15.


Switched Memory B Cells Are Increased in Oligoarticular and Polyarticular Juvenile Idiopathic Arthritis and Their Change Over Time Is Related to Response to Tumor Necrosis Factor Inhibitors.

Marasco E, Aquilani A, Cascioli S, Moneta GM, Caiello I, Farroni C, Giorda E, D'Oria V, Marafon DP, Magni-Manzoni S, Carsetti R, De Benedetti F.

Arthritis Rheumatol. 2018 Apr;70(4):606-615. doi: 10.1002/art.40410. Epub 2018 Mar 25.


ProNGF-p75NTR axis plays a proinflammatory role in inflamed joints: a novel pathogenic mechanism in chronic arthritis.

Minnone G, Soligo M, Caiello I, Prencipe G, Manni L, Marafon DP, Magni-Manzoni S, Manzo A, De Benedetti F, Bracci-Laudiero L.

RMD Open. 2017 Sep 12;3(2):e000441. doi: 10.1136/rmdopen-2017-000441. eCollection 2017. Erratum in: RMD Open. 2018 Jan 7;4(1):e000441corr1. Benedetti, Fabrizio De [corrected to De Benedetti, Fabrizio].


Neutralization of IFN-γ reverts clinical and laboratory features in a mouse model of macrophage activation syndrome.

Prencipe G, Caiello I, Pascarella A, Grom AA, Bracaglia C, Chatel L, Ferlin WG, Marasco E, Strippoli R, de Min C, De Benedetti F.

J Allergy Clin Immunol. 2018 Apr;141(4):1439-1449. doi: 10.1016/j.jaci.2017.07.021. Epub 2017 Aug 12.


Elevated circulating levels of interferon-γ and interferon-γ-induced chemokines characterise patients with macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.

Bracaglia C, de Graaf K, Pires Marafon D, Guilhot F, Ferlin W, Prencipe G, Caiello I, Davì S, Schulert G, Ravelli A, Grom AA, de Min C, De Benedetti F.

Ann Rheum Dis. 2017 Jan;76(1):166-172. doi: 10.1136/annrheumdis-2015-209020. Epub 2016 Jun 13.


Inhibition of natural killer cell cytotoxicity by interleukin-6: implications for the pathogenesis of macrophage activation syndrome.

Cifaldi L, Prencipe G, Caiello I, Bracaglia C, Locatelli F, De Benedetti F, Strippoli R.

Arthritis Rheumatol. 2015 Nov;67(11):3037-46. doi: 10.1002/art.39295.


IL-6 amplifies TLR mediated cytokine and chemokine production: implications for the pathogenesis of rheumatic inflammatory diseases.

Caiello I, Minnone G, Holzinger D, Vogl T, Prencipe G, Manzo A, De Benedetti F, Strippoli R.

PLoS One. 2014 Oct 1;9(10):e107886. doi: 10.1371/journal.pone.0107886. eCollection 2014.


Nerve growth factor downregulates inflammatory response in human monocytes through TrkA.

Prencipe G, Minnone G, Strippoli R, De Pasquale L, Petrini S, Caiello I, Manni L, De Benedetti F, Bracci-Laudiero L.

J Immunol. 2014 Apr 1;192(7):3345-54. doi: 10.4049/jimmunol.1300825. Epub 2014 Feb 28.


Inflammasome activation by cystine crystals: implications for the pathogenesis of cystinosis.

Prencipe G, Caiello I, Cherqui S, Whisenant T, Petrini S, Emma F, De Benedetti F.

J Am Soc Nephrol. 2014 Jun;25(6):1163-9. doi: 10.1681/ASN.2013060653. Epub 2014 Feb 13.


Reaching the threshold: a multilayer pathogenesis of macrophage activation syndrome.

Strippoli R, Caiello I, De Benedetti F.

J Rheumatol. 2013 Jun;40(6):761-7. doi: 10.3899/jrheum.121233. Epub 2013 Apr 15. Review.


Lack of dystrophin in mdx mice modulates the expression of genes involved in neuron survival and differentiation.

Licursi V, Caiello I, Lombardi L, De Stefano ME, Negri R, Paggi P.

Eur J Neurosci. 2012 Mar;35(5):691-701. doi: 10.1111/j.1460-9568.2011.07984.x. Epub 2012 Feb 7.


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