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Items: 1 to 50 of 125

1.

Pain-Induced Negative Affect Is Mediated via Recruitment of The Nucleus Accumbens Kappa Opioid System.

Massaly N, Copits BA, Wilson-Poe AR, Hipólito L, Markovic T, Yoon HJ, Liu S, Walicki MC, Bhatti DL, Sirohi S, Klaas A, Walker BM, Neve R, Cahill CM, Shoghi KI, Gereau RW 4th, McCall JG, Al-Hasani R, Bruchas MR, Morón JA.

Neuron. 2019 Mar 4. pii: S0896-6273(19)30164-3. doi: 10.1016/j.neuron.2019.02.029. [Epub ahead of print]

PMID:
30878290
2.

Kappa Opioid Receptors Drive a Tonic Aversive Component of Chronic Pain.

Liu SS, Pickens S, Burma NE, Ibarra-Lecue I, Yang H, Xue L, Cook C, Hakimian JK, Severino AL, Lueptow L, Komarek K, Taylor AMW, Olmstead MC, Carroll FI, Bass CE, Andrews AM, Walwyn W, Trang T, Evans CJ, Leslie F, Cahill CM.

J Neurosci. 2019 Mar 12. pii: 0274-19. doi: 10.1523/JNEUROSCI.0274-19.2019. [Epub ahead of print]

PMID:
30862664
3.

Targeting the Iron-Response Elements of the mRNAs for the Alzheimer's Amyloid Precursor Protein and Ferritin to Treat Acute Lead and Manganese Neurotoxicity.

Rogers JT, Xia N, Wong A, Bakshi R, Cahill CM.

Int J Mol Sci. 2019 Feb 25;20(4). pii: E994. doi: 10.3390/ijms20040994. Review.

4.

Fentanyl: Receptor pharmacology, abuse potential, and implications for treatment.

Comer SD, Cahill CM.

Neurosci Biobehav Rev. 2018 Dec 5. pii: S0149-7634(18)30207-0. doi: 10.1016/j.neubiorev.2018.12.005. [Epub ahead of print] Review.

PMID:
30528374
5.

Non-nociceptive roles of opioids in the CNS: opioids' effects on neurogenesis, learning, memory and affect.

Kibaly C, Xu C, Cahill CM, Evans CJ, Law PY.

Nat Rev Neurosci. 2019 Jan;20(1):5-18. doi: 10.1038/s41583-018-0092-2. Review.

PMID:
30518959
6.

Manganese causes neurotoxic iron accumulation via translational repression of amyloid precursor protein and H-Ferritin.

Venkataramani V, Doeppner TR, Willkommen D, Cahill CM, Xin Y, Ye G, Liu Y, Southon A, Aron A, Au-Yeung HY, Huang X, Lahiri DK, Wang F, Bush AI, Wulf GG, Ströbel P, Michalke B, Rogers JT.

J Neurochem. 2018 Dec;147(6):831-848. doi: 10.1111/jnc.14580. Epub 2018 Nov 19.

PMID:
30152072
7.
8.

Evidence and Function Relevance of Native DOR-MOR Heteromers.

Cahill CM, Ong E.

Handb Exp Pharmacol. 2018;247:115-127. doi: 10.1007/164_2018_112. Review.

PMID:
29633181
9.

Dissociation between morphine-induced spinal gliosis and analgesic tolerance by ultra-low-dose α2-adrenergic and cannabinoid CB1-receptor antagonists.

Grenier P, Wiercigroch D, Olmstead MC, Cahill CM.

Behav Pharmacol. 2018 Apr;29(2 and 3-Spec Issue):241-254. doi: 10.1097/FBP.0000000000000377.

PMID:
29481424
10.

S-Adenosyl Methionine and Transmethylation Pathways in Neuropsychiatric Diseases Throughout Life.

Gao J, Cahill CM, Huang X, Roffman JL, Lamon-Fava S, Fava M, Mischoulon D, Rogers JT.

Neurotherapeutics. 2018 Jan;15(1):156-175. doi: 10.1007/s13311-017-0593-0. Review.

11.

Editorial: Modulation of Reward Circuitry by Pain and Stress.

Taylor AMW, Cahill CM.

Front Psychiatry. 2017 Dec 22;8:296. doi: 10.3389/fpsyt.2017.00296. eCollection 2017. No abstract available.

12.

Quantitative texture analysis: robustness of radiomics across two digital mammography manufacturers' systems.

Mendel KR, Li H, Lan L, Cahill CM, Rael V, Abe H, Giger ML.

J Med Imaging (Bellingham). 2018 Jan;5(1):011002. doi: 10.1117/1.JMI.5.1.011002. Epub 2017 Sep 19.

13.

Universalizing anonymity anxiety.

Cahill CM.

J Law Biosci. 2016 Oct 12;3(3):647-654. doi: 10.1093/jlb/lsw043. eCollection 2016 Dec. No abstract available.

14.

Implementation of a Standardized Transfusion Protocol for Cardiac Patients Treated With Venoarterial Extracorporeal Membrane Oxygenation Is Associated With Decreased Blood Component Utilization and May Improve Clinical Outcome.

Cahill CM, Blumberg N, Schmidt AE, Knight PA, Melvin AL, Massey HT, Delehanty JM, Zebrak SB, Refaai MA.

Anesth Analg. 2018 Apr;126(4):1262-1267. doi: 10.1213/ANE.0000000000002238.

PMID:
28704244
15.

Erratum: Blocking microglial pannexin-1 channels alleviates morphine withdrawal in rodents.

Burma NE, Bonin RP, Leduc-Pessah H, Baimel C, Cairncross ZF, Mousseau M, Shankara JV, Stemkowski PL, Baimoukhametova D, Bains JS, Antle MC, Zamponi GW, Cahill CM, Borgland SL, DeKoninck Y, Trang T.

Nat Med. 2017 Jun 6;23(6):788. doi: 10.1038/nm0617-788c. No abstract available.

16.

Neuroinflammation-a co-occurring phenomenon linking chronic pain and opioid dependence.

Cahill CM, Taylor AM.

Curr Opin Behav Sci. 2017 Feb;13:171-177. doi: 10.1016/j.cobeha.2016.12.003. Epub 2017 Jan 6.

17.

Blocking microglial pannexin-1 channels alleviates morphine withdrawal in rodents.

Burma NE, Bonin RP, Leduc-Pessah H, Baimel C, Cairncross ZF, Mousseau M, Shankara JV, Stemkowski PL, Baimoukhametova D, Bains JS, Antle MC, Zamponi GW, Cahill CM, Borgland SL, De Koninck Y, Trang T.

Nat Med. 2017 Mar;23(3):355-360. doi: 10.1038/nm.4281. Epub 2017 Jan 30. Erratum in: Nat Med. 2017 Jun 6;23 (6):788.

18.

Allostatic Mechanisms of Opioid Tolerance Beyond Desensitization and Downregulation.

Cahill CM, Walwyn W, Taylor AMW, Pradhan AAA, Evans CJ.

Trends Pharmacol Sci. 2016 Nov;37(11):963-976. doi: 10.1016/j.tips.2016.08.002. Epub 2016 Sep 23. Review.

19.

Topography of microglial activation in sensory- and affect-related brain regions in chronic pain.

Taylor AM, Mehrabani S, Liu S, Taylor AJ, Cahill CM.

J Neurosci Res. 2017 Jun;95(6):1330-1335. doi: 10.1002/jnr.23883. Epub 2016 Aug 30.

20.

Neurobiology of opioid dependence in creating addiction vulnerability.

Evans CJ, Cahill CM.

F1000Res. 2016 Jul 19;5. pii: F1000 Faculty Rev-1748. doi: 10.12688/f1000research.8369.1. eCollection 2016. Review.

21.

Molecular Pharmacology of δ-Opioid Receptors.

Gendron L, Cahill CM, von Zastrow M, Schiller PW, Pineyro G.

Pharmacol Rev. 2016 Jul;68(3):631-700. doi: 10.1124/pr.114.008979. Review.

22.

A role for amyloid precursor protein translation to restore iron homeostasis and ameliorate lead (Pb) neurotoxicity.

Rogers JT, Venkataramani V, Washburn C, Liu Y, Tummala V, Jiang H, Smith A, Cahill CM.

J Neurochem. 2016 Aug;138(3):479-94. doi: 10.1111/jnc.13671.

23.

Differential Expression of the Activator Protein 1 Transcription Factor Regulates Interleukin-1ß Induction of Interleukin 6 in the Developing Enterocyte.

Cahill CM, Zhu W, Oziolor E, Yang YJ, Tam B, Rajanala S, Rogers JT, Walker WA.

PLoS One. 2016 Jan 22;11(1):e0145184. doi: 10.1371/journal.pone.0145184. eCollection 2016.

24.

Pain and Poppies: The Good, the Bad, and the Ugly of Opioid Analgesics.

Trang T, Al-Hasani R, Salvemini D, Salter MW, Gutstein H, Cahill CM.

J Neurosci. 2015 Oct 14;35(41):13879-88. doi: 10.1523/JNEUROSCI.2711-15.2015. Review.

25.

Neuroimmune Regulation of GABAergic Neurons Within the Ventral Tegmental Area During Withdrawal from Chronic Morphine.

Taylor AM, Castonguay A, Ghogha A, Vayssiere P, Pradhan AA, Xue L, Mehrabani S, Wu J, Levitt P, Olmstead MC, De Koninck Y, Evans CJ, Cahill CM.

Neuropsychopharmacology. 2016 Mar;41(4):949-59. doi: 10.1038/npp.2015.221. Epub 2015 Jul 23.

26.

Microglia disrupt mesolimbic reward circuitry in chronic pain.

Taylor AM, Castonguay A, Taylor AJ, Murphy NP, Ghogha A, Cook C, Xue L, Olmstead MC, De Koninck Y, Evans CJ, Cahill CM.

J Neurosci. 2015 Jun 3;35(22):8442-50. doi: 10.1523/JNEUROSCI.4036-14.2015.

27.

Beyond a Simple Anesthetic Effect: Lidocaine in the Diagnosis and Treatment of Interstitial Cystitis/bladder Pain Syndrome.

Henry RA, Morales A, Cahill CM.

Urology. 2015 May;85(5):1025-1033. doi: 10.1016/j.urology.2015.01.021. Review.

28.

Function coupling of otoferlin with GAD65 acts to modulate GABAergic activity.

Wu W, Rahman MN, Guo J, Roy N, Xue L, Cahill CM, Zhang S, Jia Z.

J Mol Cell Biol. 2015 Apr;7(2):168-79. doi: 10.1093/jmcb/mjv011. Epub 2015 Feb 20.

PMID:
25701657
29.

Does the kappa opioid receptor system contribute to pain aversion?

Cahill CM, Taylor AM, Cook C, Ong E, Morón JA, Evans CJ.

Front Pharmacol. 2014 Nov 17;5:253. doi: 10.3389/fphar.2014.00253. eCollection 2014. Review.

30.

Analgesia, enhancement of spinal morphine antinociception, and inhibition of tolerance by ultra-low dose of the α2A-adrenoceptor selective antagonist BRL44408.

Milne B, Jhamandas K, Sutak M, Grenier P, Cahill CM.

Eur J Pharmacol. 2014 Nov 15;743:89-97. doi: 10.1016/j.ejphar.2014.08.040. Epub 2014 Sep 19.

PMID:
25242119
31.

Correlation between ventral striatal catecholamine content and nociceptive thresholds in neuropathic mice.

Taylor AM, Murphy NP, Evans CJ, Cahill CM.

J Pain. 2014 Aug;15(8):878-85. doi: 10.1016/j.jpain.2014.05.006. Epub 2014 Jun 2.

32.

Anti-nociception mediated by a κ opioid receptor agonist is blocked by a δ receptor agonist.

Taylor AM, Roberts KW, Pradhan AA, Akbari HA, Walwyn W, Lutfy K, Carroll FI, Cahill CM, Evans CJ.

Br J Pharmacol. 2015 Jan;172(2):691-703. doi: 10.1111/bph.12810. Epub 2014 Sep 5.

33.

Toll-like receptor 4 mutant and null mice retain morphine-induced tolerance, hyperalgesia, and physical dependence.

Mattioli TA, Leduc-Pessah H, Skelhorne-Gross G, Nicol CJ, Milne B, Trang T, Cahill CM.

PLoS One. 2014 May 13;9(5):e97361. doi: 10.1371/journal.pone.0097361. eCollection 2014. Erratum in: PLoS One. 2014;9(6):e101621.

34.

Prolonged morphine treatment alters δ opioid receptor post-internalization trafficking.

Ong EW, Xue L, Olmstead MC, Cahill CM.

Br J Pharmacol. 2015 Jan;172(2):615-29. doi: 10.1111/bph.12761. Epub 2014 Jul 1.

35.

Molecular Perspectives for mu/delta Opioid Receptor Heteromers as Distinct, Functional Receptors.

Ong EW, Cahill CM.

Cells. 2014 Mar 5;3(1):152-79. doi: 10.3390/cells3010152.

36.

Migraine and reward system-or is it aversive?

Cahill CM, Cook C, Pickens S.

Curr Pain Headache Rep. 2014 May;18(5):410. doi: 10.1007/s11916-014-0410-y. Review.

37.

Changes in morphine reward in a model of neuropathic pain.

Cahill CM, Xue L, Grenier P, Magnussen C, Lecour S, Olmstead MC.

Behav Pharmacol. 2013 Jun;24(3):207-13. doi: 10.1097/FBP.0b013e3283618ac8.

38.

Stereo-selective inhibition of spinal morphine tolerance and hyperalgesia by an ultra-low dose of the alpha-2-adrenoceptor antagonist efaroxan.

Milne B, Jhamandas K, Sutak M, Grenier P, Cahill CM.

Eur J Pharmacol. 2013 Feb 28;702(1-3):227-34. doi: 10.1016/j.ejphar.2013.01.022. Epub 2013 Jan 29.

39.

Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Cl⁻ homeostasis.

Ferrini F, Trang T, Mattioli TA, Laffray S, Del'Guidice T, Lorenzo LE, Castonguay A, Doyon N, Zhang W, Godin AG, Mohr D, Beggs S, Vandal K, Beaulieu JM, Cahill CM, Salter MW, De Koninck Y.

Nat Neurosci. 2013 Feb;16(2):183-92. doi: 10.1038/nn.3295. Epub 2013 Jan 6.

40.

Myofascial pain in patients waitlisted for total knee arthroplasty.

Henry R, Cahill CM, Wood G, Hroch J, Wilson R, Cupido T, Vandenkerkhof E.

Pain Res Manag. 2012 Sep-Oct;17(5):321-7.

41.

The anticholinesterase phenserine and its enantiomer posiphen as 5'untranslated-region-directed translation blockers of the Parkinson's alpha synuclein expression.

Mikkilineni S, Cantuti-Castelvetri I, Cahill CM, Balliedier A, Greig NH, Rogers JT.

Parkinsons Dis. 2012;2012:142372. doi: 10.1155/2012/142372. Epub 2012 May 29.

42.

The role of phosphoinositide 3-kinase signaling in intestinal inflammation.

Cahill CM, Rogers JT, Walker WA.

J Signal Transduct. 2012;2012:358476. doi: 10.1155/2012/358476. Epub 2012 Apr 9.

43.

Intrathecal catheterization influences tolerance to chronic morphine in rats.

Mattioli TA, Sutak M, Milne B, Jhamandas K, Cahill CM.

Anesth Analg. 2012 Mar;114(3):690-3. doi: 10.1213/ANE.0b013e31823fad94. Epub 2011 Dec 20.

PMID:
22190548
44.

Low dose alpha-2 antagonist paradoxically enhances rat norepinephrine and clonidine analgesia.

Milne B, Sutak M, Cahill CM, Jhamandas K.

Anesth Analg. 2011 Jun;112(6):1500-3. doi: 10.1213/ANE.0b013e3182121bae. Epub 2011 May 5.

PMID:
21543786
45.

A piece of the puzzle is revealed for delta opioid receptor-mediated analgesia.

Cahill CM, Taylor A.

Pain. 2011 Jun;152(6):1217-8. doi: 10.1016/j.pain.2011.02.006. Epub 2011 Feb 17. No abstract available.

46.

Mapping of neural activity produced by thermal pain in the healthy human spinal cord and brain stem: a functional magnetic resonance imaging study.

Cahill CM, Stroman PW.

Magn Reson Imaging. 2011 Apr;29(3):342-52. doi: 10.1016/j.mri.2010.10.007. Epub 2011 Jan 17.

47.

The alpha-synuclein 5'untranslated region targeted translation blockers: anti-alpha synuclein efficacy of cardiac glycosides and Posiphen.

Rogers JT, Mikkilineni S, Cantuti-Castelvetri I, Smith DH, Huang X, Bandyopadhyay S, Cahill CM, Maccecchini ML, Lahiri DK, Greig NH.

J Neural Transm (Vienna). 2011 Mar;118(3):493-507. doi: 10.1007/s00702-010-0513-5. Epub 2011 Jan 8.

PMID:
21221670
48.

Increased abundance of opioid receptor heteromers after chronic morphine administration.

Gupta A, Mulder J, Gomes I, Rozenfeld R, Bushlin I, Ong E, Lim M, Maillet E, Junek M, Cahill CM, Harkany T, Devi LA.

Sci Signal. 2010 Jul 20;3(131):ra54. doi: 10.1126/scisignal.2000807.

49.

Selective translational control of the Alzheimer amyloid precursor protein transcript by iron regulatory protein-1.

Cho HH, Cahill CM, Vanderburg CR, Scherzer CR, Wang B, Huang X, Rogers JT.

J Biol Chem. 2010 Oct 8;285(41):31217-32. doi: 10.1074/jbc.M110.149161. Epub 2010 Jun 17.

50.

Ultra-low dose naltrexone attenuates chronic morphine-induced gliosis in rats.

Mattioli TA, Milne B, Cahill CM.

Mol Pain. 2010 Apr 16;6:22. doi: 10.1186/1744-8069-6-22.

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