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Items: 33


Vaccine-Mediated Induction of an Ebolavirus Cross-Species Antibody Binding to Conserved Epitopes on the Glycoprotein Heptad Repeat 2/Membrane-Proximal External Junction.

Cagigi A, Ploquin A, Niezold T, Zhou Y, Tsybovsky Y, Misasi J, Sullivan NJ.

J Infect Dis. 2018 Nov 22;218(suppl_5):S537-S544. doi: 10.1093/infdis/jiy450.


Vaccine Generation of Protective Ebola Antibodies and Identification of Conserved B-Cell Signatures.

Cagigi A, Misasi J, Ploquin A, Stanley DA, Ambrozak D, Tsybovsky Y, Mason RD, Roederer M, Sullivan NJ.

J Infect Dis. 2018 Nov 22;218(suppl_5):S528-S536. doi: 10.1093/infdis/jiy333.


Functional interrogation and mining of natively paired human VH:VL antibody repertoires.

Wang B, DeKosky BJ, Timm MR, Lee J, Normandin E, Misasi J, Kong R, McDaniel JR, Delidakis G, Leigh KE, Niezold T, Choi CW, Viox EG, Fahad A, Cagigi A, Ploquin A, Leung K, Yang ES, Kong WP, Voss WN, Schmidt AG, Moody MA, Ambrozak DR, Henry AR, Laboune F, Ledgerwood JE, Graham BS, Connors M, Douek DC, Sullivan NJ, Ellington AD, Mascola JR, Georgiou G.

Nat Biotechnol. 2018 Feb;36(2):152-155. doi: 10.1038/nbt.4052. Epub 2018 Jan 8.


Perturbation of B Cell Gene Expression Persists in HIV-Infected Children Despite Effective Antiretroviral Therapy and Predicts H1N1 Response.

Cotugno N, De Armas L, Pallikkuth S, Rinaldi S, Issac B, Cagigi A, Rossi P, Palma P, Pahwa S.

Front Immunol. 2017 Sep 11;8:1083. doi: 10.3389/fimmu.2017.01083. eCollection 2017.


Induction of IL21 in Peripheral T Follicular Helper Cells Is an Indicator of Influenza Vaccine Response in a Previously Vaccinated HIV-Infected Pediatric Cohort.

de Armas LR, Cotugno N, Pallikkuth S, Pan L, Rinaldi S, Sanchez MC, Gonzalez L, Cagigi A, Rossi P, Palma P, Pahwa S.

J Immunol. 2017 Mar 1;198(5):1995-2005. doi: 10.4049/jimmunol.1601425. Epub 2017 Jan 27.


Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody.

Corti D, Misasi J, Mulangu S, Stanley DA, Kanekiyo M, Wollen S, Ploquin A, Doria-Rose NA, Staupe RP, Bailey M, Shi W, Choe M, Marcus H, Thompson EA, Cagigi A, Silacci C, Fernandez-Rodriguez B, Perez L, Sallusto F, Vanzetta F, Agatic G, Cameroni E, Kisalu N, Gordon I, Ledgerwood JE, Mascola JR, Graham BS, Muyembe-Tamfun JJ, Trefry JC, Lanzavecchia A, Sullivan NJ.

Science. 2016 Mar 18;351(6279):1339-42. doi: 10.1126/science.aad5224. Epub 2016 Feb 25.


Structural and molecular basis for Ebola virus neutralization by protective human antibodies.

Misasi J, Gilman MS, Kanekiyo M, Gui M, Cagigi A, Mulangu S, Corti D, Ledgerwood JE, Lanzavecchia A, Cunningham J, Muyembe-Tamfun JJ, Baxa U, Graham BS, Xiang Y, Sullivan NJ, McLellan JS.

Science. 2016 Mar 18;351(6279):1343-6. doi: 10.1126/science.aad6117. Epub 2016 Feb 25.


Cellular immune profile of kidney transplant patients developing anti-HLA antibodies during childhood.

Santilli V, Cagigi A, Guzzo I, Rinaldi S, Mora N, Zotta F, Piazza A, Rossi P, Emma F, Dello Strologo L, Palma P.

Pediatr Nephrol. 2016 Jun;31(6):1001-10. doi: 10.1007/s00467-015-3274-4. Epub 2015 Dec 21.


Downfall of the current antibody correlates of influenza vaccine response in yearly vaccinated subjects: Toward qualitative rather than quantitative assays.

Cagigi A, Cotugno N, Rinaldi S, Santilli V, Rossi P, Palma P.

Pediatr Allergy Immunol. 2016 Feb;27(1):22-7. doi: 10.1111/pai.12483. Epub 2015 Oct 20. Review.


Premature B-cell senescence as a consequence of chronic immune activation.

Palma P, Rinaldi S, Cotugno N, Santilli V, Pahwa S, Rossi P, Cagigi A.

Hum Vaccin Immunother. 2014;10(7):2083-8. doi: 10.4161/hv.28698. Review.


Frequency and phenotype of B cell subpopulations in young and aged HIV-1 infected patients receiving ART.

Amu S, Lavy-Shahaf G, Cagigi A, Hejdeman B, Nozza S, Lopalco L, Mehr R, Chiodi F.

Retrovirology. 2014 Sep 11;11:76. doi: 10.1186/s12977-014-0076-x.


Defective B-cell proliferation and maintenance of long-term memory in patients with chronic granulomatous disease.

Cotugno N, Finocchi A, Cagigi A, Di Matteo G, Chiriaco M, Di Cesare S, Rossi P, Aiuti A, Palma P, Douagi I.

J Allergy Clin Immunol. 2015 Mar;135(3):753-61.e2. doi: 10.1016/j.jaci.2014.07.012. Epub 2014 Aug 29.


B-sides serologic markers of immunogenicity in kidney transplanted patients: report from 2012-2013 flu vaccination experience.

Rinaldi S, Cagigi A, Santilli V, Zotta F, di Martino A, Castrucci MR, Donatelli I, Poggi E, Piazza A, Campana A, Guzzo I, Villani A, Rossi P, Dello Strologo L, Palma P.

Transplantation. 2014 Aug 15;98(3):259-66. doi: 10.1097/TP.0000000000000209.


Vaccine risk assessment in children with a referred reaction to a previous vaccine dose: 2009-2011 retrospective report at the Bambino Gesu' children hospital, Rome, Italy.

Nicolosi L, Vittucci A, Mancini R, Bozzola E, Cagigi A, Grandin A, Villani A.

Ital J Pediatr. 2014 Mar 31;40:31. doi: 10.1186/1824-7288-40-31.


Early highly active antiretroviral therapy enhances B-cell longevity: a 5 year follow up.

Cagigi A, Rinaldi S, Cotugno N, Manno EC, Santilli V, Mora N, Zangari P, Aquilani A, Tchidjou KH, Giaquinto C, Bernardi S, Rossi P, Palma P.

Pediatr Infect Dis J. 2014 May;33(5):e126-31. doi: 10.1097/INF.0000000000000144.


Antibody but not memory B-cell responses are tuned-down in vertically HIV-1 infected children and young individuals being vaccinated yearly against influenza.

Rinaldi S, Zangari P, Cotugno N, Manno EC, Brolatti N, Castrucci MR, Donatelli I, Rossi P, Palma P, Cagigi A.

Vaccine. 2014 Feb 3;32(6):657-63. doi: 10.1016/j.vaccine.2013.12.008. Epub 2013 Dec 13.


Premature immune senescence during HIV-1 vertical infection relates with response to influenza vaccination.

Cagigi A, Rinaldi S, Di Martino A, Manno EC, Zangari P, Aquilani A, Cotugno N, Nicolosi L, Villani A, Bernardi S, Donatelli I, Pahwa S, Rossi P, Palma P.

J Allergy Clin Immunol. 2014 Feb;133(2):592-4. doi: 10.1016/j.jaci.2013.10.003. Epub 2013 Nov 28. No abstract available.


Premature ageing of the immune system relates to increased anti-lymphocyte antibodies (ALA) after an immunization in HIV-1-infected and kidney-transplanted patients.

Cagigi A, Rinaldi S, Santilli V, Mora N, C Manno E, Cotugno N, Zangari P, Aquilani A, Guzzo I, Dello Strologo L, Rossi P, Palma P.

Clin Exp Immunol. 2013 Nov;174(2):274-80. doi: 10.1111/cei.12173.


Relation of activation-induced deaminase (AID) expression with antibody response to A(H1N1)pdm09 vaccination in HIV-1 infected patients.

Cagigi A, Pensieroso S, Ruffin N, Sammicheli S, Thorstensson R, Pan-Hammarström Q, Hejdeman B, Nilsson A, Chiodi F.

Vaccine. 2013 Apr 26;31(18):2231-7. doi: 10.1016/j.vaccine.2013.03.002. Epub 2013 Mar 14.


Kinetics of antibody and memory B cell responses after MMR immunization in children and young adults.

Kakoulidou M, Ingelman-Sundberg H, Johansson E, Cagigi A, Farouk SE, Nilsson A, Johansen K.

Vaccine. 2013 Jan 11;31(4):711-7. doi: 10.1016/j.vaccine.2012.11.031. Epub 2012 Nov 19.


Immune reconstitution and vaccination outcome in HIV-1 infected children: present knowledge and future directions.

Cagigi A, Cotugno N, Giaquinto C, Nicolosi L, Bernardi S, Rossi P, Douagi I, Palma P.

Hum Vaccin Immunother. 2012 Dec 1;8(12):1784-94. doi: 10.4161/hv.21827. Epub 2012 Aug 21. Review.


Soluble CD27 induces IgG production through activation of antigen-primed B cells.

Dang LV, Nilsson A, Ingelman-Sundberg H, Cagigi A, Gelinck LB, Titanji K, De Milito A, Grutzmeier S, Hedlund J, Kroon FP, Chiodi F.

J Intern Med. 2012 Mar;271(3):282-93. doi: 10.1111/j.1365-2796.2011.02444.x. Epub 2011 Sep 14.


Mapping of switch recombination junctions, a tool for studying DNA repair pathways during immunoglobulin class switching.

Stavnezer J, Björkman A, Du L, Cagigi A, Pan-Hammarström Q.

Adv Immunol. 2010;108:45-109. doi: 10.1016/B978-0-12-380995-7.00003-3. Review.


Dysfunctional B-cell responses during HIV-1 infection: implication for influenza vaccination and highly active antiretroviral therapy.

Cagigi A, Nilsson A, Pensieroso S, Chiodi F.

Lancet Infect Dis. 2010 Jul;10(7):499-503. doi: 10.1016/S1473-3099(10)70117-1.


The impact of active HIV-1 replication on the physiological age-related decline of immature-transitional B-cells in HIV-1 infected children.

Cagigi A, Palma P, Nilsson A, Di Cesare S, Pensieroso S, Kakoulidou M, Bernardi S, Rossi P, Chiodi F.

AIDS. 2010 Aug 24;24(13):2075-80. doi: 10.1097/QAD.0b013e32833c3298.


Cytotoxic T-lymphocytes secrete soluble factors that induce caspase-mediated apoptosis in glioblastoma cell lines.

Cagigi A, Nilsson A, Levitsky V, Sabri F.

J Neuroimmunol. 2010 Aug 25;225(1-2):34-42. doi: 10.1016/j.jneuroim.2010.04.009. Epub 2010 May 16.


Changes in chemokines and chemokine receptor expression on tonsillar B cells upon Epstein-Barr virus infection.

Ehlin-Henriksson B, Liang W, Cagigi A, Mowafi F, Klein G, Nilsson A.

Immunology. 2009 Aug;127(4):549-57. doi: 10.1111/j.1365-2567.2008.03029.x.


Timing of HAART defines the integrity of memory B cells and the longevity of humoral responses in HIV-1 vertically-infected children.

Pensieroso S, Cagigi A, Palma P, Nilsson A, Capponi C, Freda E, Bernardi S, Thorstensson R, Chiodi F, Rossi P.

Proc Natl Acad Sci U S A. 2009 May 12;106(19):7939-44. doi: 10.1073/pnas.0901702106. Epub 2009 Apr 27.


CD27(-) B-cells produce class switched and somatically hyper-mutated antibodies during chronic HIV-1 infection.

Cagigi A, Du L, Dang LV, Grutzmeier S, Atlas A, Chiodi F, Pan-Hammarström Q, Nilsson A.

PLoS One. 2009;4(5):e5427. doi: 10.1371/journal.pone.0005427. Epub 2009 May 1.


Altered expression of the receptor-ligand pair CXCR5/CXCL13 in B cells during chronic HIV-1 infection.

Cagigi A, Mowafi F, Phuong Dang LV, Tenner-Racz K, Atlas A, Grutzmeier S, Racz P, Chiodi F, Nilsson A.

Blood. 2008 Dec 1;112(12):4401-10. doi: 10.1182/blood-2008-02-140426. Epub 2008 Sep 9.


B cell immunopathology during HIV-1 infection: lessons to learn for HIV-1 vaccine design.

Cagigi A, Nilsson A, De Milito A, Chiodi F.

Vaccine. 2008 Jun 6;26(24):3016-25. doi: 10.1016/j.vaccine.2007.11.063. Epub 2007 Dec 17. Review.


Chemokine CXCL12 enhances proliferation in pre-B-ALL via STAT5 activation.

Mowafi F, Cagigi A, Matskova L, Björk O, Chiodi F, Nilsson A.

Pediatr Blood Cancer. 2008 Apr;50(4):812-7.


Loss of memory B cells impairs maintenance of long-term serologic memory during HIV-1 infection.

Titanji K, De Milito A, Cagigi A, Thorstensson R, Grützmeier S, Atlas A, Hejdeman B, Kroon FP, Lopalco L, Nilsson A, Chiodi F.

Blood. 2006 Sep 1;108(5):1580-7. Epub 2006 Apr 27.

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