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Items: 1 to 50 of 61

1.

Inhibitor of Differentiation-1 Sustains Mutant KRAS-Driven Progression, Maintenance, and Metastasis of Lung Adenocarcinoma via Regulation of a FOSL1 Network.

Román M, López I, Guruceaga E, Baraibar I, Ecay M, Collantes M, Nadal E, Vallejo A, Cadenas S, Miguel ME, Jang JH, Martin-Uriz PS, Castro-Labrador L, Vilas-Zornoza A, Lara-Astiaso D, Ponz-Sarvise M, Rolfo C, Santos ES, Raez LE, Taverna S, Behrens C, Weder W, Wistuba II, Vicent S, Gil-Bazo I.

Cancer Res. 2019 Feb 1;79(3):625-638. doi: 10.1158/0008-5472.CAN-18-1479. Epub 2018 Dec 18.

PMID:
30563891
2.

Mitochondrial uncoupling, ROS generation and cardioprotection.

Cadenas S.

Biochim Biophys Acta Bioenerg. 2018 Sep;1859(9):940-950. doi: 10.1016/j.bbabio.2018.05.019. Epub 2018 May 31. Review.

PMID:
29859845
3.

ROS and redox signaling in myocardial ischemia-reperfusion injury and cardioprotection.

Cadenas S.

Free Radic Biol Med. 2018 Mar;117:76-89. doi: 10.1016/j.freeradbiomed.2018.01.024. Epub 2018 Jan 31. Review.

PMID:
29373843
4.

Podocytes are new cellular targets of haemoglobin-mediated renal damage.

Rubio-Navarro A, Sanchez-Niño MD, Guerrero-Hue M, García-Caballero C, Gutiérrez E, Yuste C, Sevillano Á, Praga M, Egea J, Román E, Cannata P, Ortega R, Cortegano I, de Andrés B, Gaspar ML, Cadenas S, Ortiz A, Egido J, Moreno JA.

J Pathol. 2018 Mar;244(3):296-310. doi: 10.1002/path.5011. Epub 2018 Jan 10.

PMID:
29205354
5.

Rapamycin negatively impacts insulin signaling, glucose uptake and uncoupling protein-1 in brown adipocytes.

García-Casarrubios E, de Moura C, Arroba AI, Pescador N, Calderon-Dominguez M, Garcia L, Herrero L, Serra D, Cadenas S, Reis F, Carvalho E, Obregon MJ, Valverde ÁM.

Biochim Biophys Acta. 2016 Dec;1861(12 Pt A):1929-1941. doi: 10.1016/j.bbalip.2016.09.016. Epub 2016 Sep 26.

PMID:
27686967
6.

Heme-Oxygenase I and PCG-1α Regulate Mitochondrial Biogenesis via Microglial Activation of Alpha7 Nicotinic Acetylcholine Receptors Using PNU282987.

Navarro E, Gonzalez-Lafuente L, Pérez-Liébana I, Buendia I, López-Bernardo E, Sánchez-Ramos C, Prieto I, Cuadrado A, Satrustegui J, Cadenas S, Monsalve M, López MG.

Antioxid Redox Signal. 2017 Jul 10;27(2):93-105. doi: 10.1089/ars.2016.6698. Epub 2016 Sep 30.

PMID:
27554853
7.

COX7A2L Is a Mitochondrial Complex III Binding Protein that Stabilizes the III2+IV Supercomplex without Affecting Respirasome Formation.

Pérez-Pérez R, Lobo-Jarne T, Milenkovic D, Mourier A, Bratic A, García-Bartolomé A, Fernández-Vizarra E, Cadenas S, Delmiro A, García-Consuegra I, Arenas J, Martín MA, Larsson NG, Ugalde C.

Cell Rep. 2016 Aug 30;16(9):2387-98. doi: 10.1016/j.celrep.2016.07.081. Epub 2016 Aug 18.

8.

Spanish Registry of Patients With Alpha-1 Antitrypsin Deficiency: Database Evaluation and Population Analysis.

Lara B, Blanco I, Martínez MT, Rodríguez E, Bustamante A, Casas F, Cadenas S, Hernández JM, Lázaro L, Torres M, Curi S, Esquinas C, Dasí F, Escribano A, Herrero I, Martínez-Delgado B, Michel FJ, Rodríguez-Frías F, Miravitlles M.

Arch Bronconeumol. 2017 Jan;53(1):13-18. doi: 10.1016/j.arbres.2016.05.003. Epub 2016 Jun 17. English, Spanish.

9.

Antioxidant responses and cellular adjustments to oxidative stress.

Espinosa-Diez C, Miguel V, Mennerich D, Kietzmann T, Sánchez-Pérez P, Cadenas S, Lamas S.

Redox Biol. 2015 Dec;6:183-97. doi: 10.1016/j.redox.2015.07.008. Epub 2015 Jul 21. Review.

10.

4-Hydroxynonenal induces Nrf2-mediated UCP3 upregulation in mouse cardiomyocytes.

López-Bernardo E, Anedda A, Sánchez-Pérez P, Acosta-Iborra B, Cadenas S.

Free Radic Biol Med. 2015 Nov;88(Pt B):427-438. doi: 10.1016/j.freeradbiomed.2015.03.032. Epub 2015 Apr 3.

PMID:
25843654
11.

TSH effects on thermogenesis in rat brown adipocytes.

Martinez-deMena R, Anedda A, Cadenas S, Obregon MJ.

Mol Cell Endocrinol. 2015 Mar 15;404:151-8. doi: 10.1016/j.mce.2015.01.028. Epub 2015 Feb 7.

PMID:
25662278
12.

Differential proteomic profiling unveils new molecular mechanisms associated with mitochondrial complex III deficiency.

Marín-Buera L, García-Bartolomé A, Morán M, López-Bernardo E, Cadenas S, Hidalgo B, Sánchez R, Seneca S, Arenas J, Martín MA, Ugalde C.

J Proteomics. 2015 Jan 15;113:38-56. doi: 10.1016/j.jprot.2014.09.007. Epub 2014 Sep 18.

13.

Indications for active case searches and intravenous alpha-1 antitrypsin treatment for patients with alpha-1 antitrypsin deficiency chronic pulmonary obstructive disease: an update.

Casas F, Blanco I, Martínez MT, Bustamante A, Miravitlles M, Cadenas S, Hernández JM, Lázaro L, Rodríguez E, Rodríguez-Frías F, Torres M, Lara B.

Arch Bronconeumol. 2015 Apr;51(4):185-92. doi: 10.1016/j.arbres.2014.05.008. Epub 2014 Jul 12. English, Spanish.

14.

The transcription factor Nrf2 promotes survival by enhancing the expression of uncoupling protein 3 under conditions of oxidative stress.

Anedda A, López-Bernardo E, Acosta-Iborra B, Saadeh Suleiman M, Landázuri MO, Cadenas S.

Free Radic Biol Med. 2013 Aug;61:395-407. doi: 10.1016/j.freeradbiomed.2013.04.007. Epub 2013 Apr 16.

PMID:
23597505
15.

Superoxide anion mediates the L-selectin down-regulation induced by non-steroidal anti-inflammatory drugs in human neutrophils.

Domínguez-Luis M, Herrera-García A, Arce-Franco M, Armas-González E, Rodríguez-Pardo M, Lorenzo-Díaz F, Feria M, Cadenas S, Sánchez-Madrid F, Díaz-González F.

Biochem Pharmacol. 2013 Jan 15;85(2):245-56. doi: 10.1016/j.bcp.2012.10.024. Epub 2012 Nov 8.

PMID:
23142710
16.

Induction of the mitochondrial NDUFA4L2 protein by HIF-1α decreases oxygen consumption by inhibiting Complex I activity.

Tello D, Balsa E, Acosta-Iborra B, Fuertes-Yebra E, Elorza A, Ordóñez Á, Corral-Escariz M, Soro I, López-Bernardo E, Perales-Clemente E, Martínez-Ruiz A, Enríquez JA, Aragonés J, Cadenas S, Landázuri MO.

Cell Metab. 2011 Dec 7;14(6):768-79. doi: 10.1016/j.cmet.2011.10.008. Epub 2011 Nov 17.

17.

Factors associated with the evolution of lung function in patients with alpha-1 antitrypsin deficiency in the Spanish registry.

Tirado-Conde G, Lara B, Casas F, Blanco I, Bustamante A, Cadenas S, Martínez MT, Lázaro L, Torres M, Hernández Pérez JM, Vidal R, Miravitlles M.

Arch Bronconeumol. 2011 Oct;47(10):495-503. doi: 10.1016/j.arbres.2011.06.002. Epub 2011 Jul 27. English, Spanish.

18.

Functional evidence for nitric oxide production by skeletal-muscle mitochondria from lipopolysaccharide-treated mice.

Aguirre E, López-Bernardo E, Cadenas S.

Mitochondrion. 2012 Jan;12(1):126-31. doi: 10.1016/j.mito.2011.05.010. Epub 2011 Jun 12.

PMID:
21664300
19.

Nitric oxide signaling: classical, less classical, and nonclassical mechanisms.

Martínez-Ruiz A, Cadenas S, Lamas S.

Free Radic Biol Med. 2011 Jul 1;51(1):17-29. doi: 10.1016/j.freeradbiomed.2011.04.010. Epub 2011 Apr 13. Review. Erratum in: Free Radic Biol Med. 2011 Aug 1;51(3):791.

PMID:
21549190
20.

Mitochondrial reprogramming through cardiac oxygen sensors in ischaemic heart disease.

Cadenas S, Aragonés J, Landázuri MO.

Cardiovasc Res. 2010 Nov 1;88(2):219-28. doi: 10.1093/cvr/cvq256. Epub 2010 Aug 2. Review.

PMID:
20679415
21.

GDP and carboxyatractylate inhibit 4-hydroxynonenal-activated proton conductance to differing degrees in mitochondria from skeletal muscle and heart.

Aguirre E, Cadenas S.

Biochim Biophys Acta. 2010 Oct;1797(10):1716-26. doi: 10.1016/j.bbabio.2010.06.009. Epub 2010 Jun 26.

22.

Kinetic model of the inhibition of respiration by endogenous nitric oxide in intact cells.

Aguirre E, Rodríguez-Juárez F, Bellelli A, Gnaiger E, Cadenas S.

Biochim Biophys Acta. 2010 May;1797(5):557-65. doi: 10.1016/j.bbabio.2010.01.033. Epub 2010 Feb 6.

23.

Increase in mitochondrial biogenesis, oxidative stress, and glycolysis in murine lymphomas.

Samper E, Morgado L, Estrada JC, Bernad A, Hubbard A, Cadenas S, Melov S.

Free Radic Biol Med. 2009 Feb 1;46(3):387-96. doi: 10.1016/j.freeradbiomed.2008.10.036. Epub 2008 Oct 30.

24.
25.

Nitric oxide regulates mitochondrial oxidative stress protection via the transcriptional coactivator PGC-1alpha.

Borniquel S, Valle I, Cadenas S, Lamas S, Monsalve M.

FASEB J. 2006 Sep;20(11):1889-91. Epub 2006 Aug 4.

PMID:
16891621
26.

Loss of apoptosis-inducing factor leads to an increase in reactive oxygen species, and an impairment of respiration that can be reversed by antioxidants.

Apostolova N, Cervera AM, Victor VM, Cadenas S, Sanjuan-Pla A, Alvarez-Barrientos A, Esplugues JV, McCreath KJ.

Cell Death Differ. 2006 Feb;13(2):354-7. No abstract available.

27.

Regulation of hypoxia-inducible factor-1alpha by nitric oxide through mitochondria-dependent and -independent pathways.

Mateo J, García-Lecea M, Cadenas S, Hernández C, Moncada S.

Biochem J. 2003 Dec 1;376(Pt 2):537-44.

28.

Fighting the stranger-antioxidant protection against endotoxin toxicity.

Cadenas S, Cadenas AM.

Toxicology. 2002 Oct 30;180(1):45-63. Review.

PMID:
12324199
29.

Oxidative damage and phospholipid fatty acyl composition in skeletal muscle mitochondria from mice underexpressing or overexpressing uncoupling protein 3.

Brand MD, Pamplona R, Portero-Otín M, Requena JR, Roebuck SJ, Buckingham JA, Clapham JC, Cadenas S.

Biochem J. 2002 Dec 1;368(Pt 2):597-603.

30.

Superoxide activates mitochondrial uncoupling proteins.

Echtay KS, Roussel D, St-Pierre J, Jekabsons MB, Cadenas S, Stuart JA, Harper JA, Roebuck SJ, Morrison A, Pickering S, Clapham JC, Brand MD.

Nature. 2002 Jan 3;415(6867):96-9.

PMID:
11780125
31.

The basal proton conductance of skeletal muscle mitochondria from transgenic mice overexpressing or lacking uncoupling protein-3.

Cadenas S, Echtay KS, Harper JA, Jekabsons MB, Buckingham JA, Grau E, Abuin A, Chapman H, Clapham JC, Brand MD.

J Biol Chem. 2002 Jan 25;277(4):2773-8. Epub 2001 Nov 13.

32.

Mitochondrial proton leak and the uncoupling protein 1 homologues.

Stuart JA, Cadenas S, Jekabsons MB, Roussel D, Brand MD.

Biochim Biophys Acta. 2001 Mar 1;1504(1):144-58. Review.

33.

AMP decreases the efficiency of skeletal-muscle mitochondria.

Cadenas S, Buckingham JA, St-Pierre J, Dickinson K, Jones RB, Brand MD.

Biochem J. 2000 Oct 15;351 Pt 2:307-11.

34.

Mice overexpressing human uncoupling protein-3 in skeletal muscle are hyperphagic and lean.

Clapham JC, Arch JR, Chapman H, Haynes A, Lister C, Moore GB, Piercy V, Carter SA, Lehner I, Smith SA, Beeley LJ, Godden RJ, Herrity N, Skehel M, Changani KK, Hockings PD, Reid DG, Squires SM, Hatcher J, Trail B, Latcham J, Rastan S, Harper AJ, Cadenas S, Buckingham JA, Brand MD, Abuin A.

Nature. 2000 Jul 27;406(6794):415-8.

PMID:
10935638
35.
36.

UCP2 and UCP3 rise in starved rat skeletal muscle but mitochondrial proton conductance is unchanged.

Cadenas S, Buckingham JA, Samec S, Seydoux J, Din N, Dulloo AG, Brand MD.

FEBS Lett. 1999 Dec 3;462(3):257-60.

37.
38.

The rate of free radical production as a determinant of the rate of aging: evidence from the comparative approach.

Perez-Campo R, López-Torres M, Cadenas S, Rojas C, Barja G.

J Comp Physiol B. 1998 Apr;168(3):149-58. Review.

PMID:
9591361
39.

Endotoxin increases oxidative injury to proteins in guinea pig liver: protection by dietary vitamin C.

Cadenas S, Rojas C, Barja G.

Pharmacol Toxicol. 1998 Jan;82(1):11-8.

PMID:
9527640
40.
41.

Vitamin E decreases urine lipid peroxidation products in young healthy human volunteers under normal conditions.

Cadenas S, Rojas C, Méndez J, Herrero A, Barja G.

Pharmacol Toxicol. 1996 Nov;79(5):247-53.

PMID:
8936558
42.

Effect of dietary vitamin E levels on fatty acid profiles and nonenzymatic lipid peroxidation in the guinea pig liver.

Barja G, Cadenas S, Rojas C, Pérez-Campo R, López-Torres M, Prat J, Pamplona R.

Lipids. 1996 Sep;31(9):963-70.

PMID:
8882976
43.

Phospholipid hydroperoxides and lipid peroxidation in liver and plasma of ODS rats supplemented with alpha-tocopherol and ascorbic acid.

Cadenas S, Lertsiri S, Otsuka M, Barja G, Miyazawa T.

Free Radic Res. 1996 Jun;24(6):485-93.

PMID:
8804991
44.

Low fatty acid unsaturation protects against lipid peroxidation in liver mitochondria from long-lived species: the pigeon and human case.

Pamplona R, Prat J, Cadenas S, Rojas C, Pérez-Campo R, López Torres M, Barja G.

Mech Ageing Dev. 1996 Jan 5;86(1):53-66.

PMID:
8866736
45.
46.

Endotoxin depletes ascorbate in the guinea pig heart. Protective effects of vitamins C and E against oxidative stress.

Rojas C, Cadenas S, Herrero A, Méndez J, Barja G.

Life Sci. 1996;59(8):649-57.

PMID:
8761015
47.

Vitamin E protects guinea pig liver from lipid peroxidation without depressing levels of antioxidants.

Cadenas S, Rojas C, Pérez-Campo R, López-Torres M, Barja G.

Int J Biochem Cell Biol. 1995 Nov;27(11):1175-81.

PMID:
7584603
48.

Effect of vitamin C on antioxidants, lipid peroxidation, and GSH system in the normal guinea pig heart.

Rojas C, Cadenas S, Pérez-Campo R, López-Torres M, Barja G.

J Nutr Sci Vitaminol (Tokyo). 1994 Oct;40(5):411-20.

PMID:
7891202
49.
50.

Dietary vitamin C decreases endogenous protein oxidative damage, malondialdehyde, and lipid peroxidation and maintains fatty acid unsaturation in the guinea pig liver.

Barja G, López-Torres M, Pérez-Campo R, Rojas C, Cadenas S, Prat J, Pamplona R.

Free Radic Biol Med. 1994 Aug;17(2):105-15.

PMID:
7959171

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