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Items: 1 to 20 of 268


Exploring the molecular basis of neuronal excitability in a vocal learner.

Friedrich SR, Lovell PV, Kaser TM, Mello CV.

BMC Genomics. 2019 Aug 2;20(1):629. doi: 10.1186/s12864-019-5871-2.


Antiallodynic effects of the selective NaV1.7 inhibitor Pn3a in a mouse model of acute postsurgical pain: evidence for analgesic synergy with opioids and baclofen.

Mueller A, Starobova H, Morgan M, Dekan Z, Cheneval O, Schroeder CI, Alewood PF, Deuis JR, Vetter I.

Pain. 2019 Aug;160(8):1766-1780. doi: 10.1097/j.pain.0000000000001567.


Tissue- and cell-specific expression of a splice variant in the II-III cytoplasmic loop of Cacna1b.

Bunda A, LaCarubba B, Akiki M, Andrade A.

FEBS Open Bio. 2019 Sep;9(9):1603-1616. doi: 10.1002/2211-5463.12701. Epub 2019 Jul 28.


Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.

Soerensen M, Li W, Debrabant B, Nygaard M, Mengel-From J, Frost M, Christensen K, Christiansen L, Tan Q.

Biogerontology. 2019 Oct;20(5):627-647. doi: 10.1007/s10522-019-09818-1. Epub 2019 Jun 28.


Proestrus Differentially Regulates Expression of Ion Channel and Calcium Homeostasis Genes in GnRH Neurons of Mice.

Vastagh C, Solymosi N, Farkas I, Liposits Z.

Front Mol Neurosci. 2019 May 31;12:137. doi: 10.3389/fnmol.2019.00137. eCollection 2019.


Transcriptome analysis of juvenile genetically improved farmed tilapia (Oreochromis niloticus) livers by dietary resveratrol supplementation.

Zheng Y, Hu G, Wu W, Zhao Z, Meng S, Fan L, Song C, Qiu L, Chen J.

Comp Biochem Physiol C Toxicol Pharmacol. 2019 Sep;223:1-8. doi: 10.1016/j.cbpc.2019.04.011. Epub 2019 Apr 24.


Bi-allelic Loss-of-Function CACNA1B Mutations in Progressive Epilepsy-Dyskinesia.

Gorman KM, Meyer E, Grozeva D, Spinelli E, McTague A, Sanchis-Juan A, Carss KJ, Bryant E, Reich A, Schneider AL, Pressler RM, Simpson MA, Debelle GD, Wassmer E, Morton J, Sieciechowicz D, Jan-Kamsteeg E, Paciorkowski AR, King MD, Cross JH, Poduri A, Mefford HC, Scheffer IE, Haack TB, McCullagh G; Deciphering Developmental Disorders Study; UK10K Consortium; NIHR BioResource, Millichap JJ, Carvill GL, Clayton-Smith J, Maher ER, Raymond FL, Kurian MA.

Am J Hum Genet. 2019 May 2;104(5):948-956. doi: 10.1016/j.ajhg.2019.03.005. Epub 2019 Apr 11.


Anti-allodynic effects of the selective NaV1.7 inhibitor Pn3a in a mouse model of acute post-surgical pain: evidence for analgesic synergy with opioids and baclofen.

Mueller A, Starobova H, Morgan M, Dekan Z, Cheneval O, Schroeder CI, Alewood PF, Deuis JR, Vetter I.

Pain. 2019 Mar 21. doi: 10.1097/j.pain.0000000000001567. [Epub ahead of print]


Isoflurane Inhibits Dopaminergic Synaptic Vesicle Exocytosis Coupled to CaV2.1 and CaV2.2 in Rat Midbrain Neurons.

Torturo CL, Zhou ZY, Ryan TA, Hemmings HC.

eNeuro. 2019 Jan 24;6(1). pii: ENEURO.0278-18.2018. doi: 10.1523/ENEURO.0278-18.2018. eCollection 2019 Jan-Feb.


CaV2.1 α1 Subunit Expression Regulates Presynaptic CaV2.1 Abundance and Synaptic Strength at a Central Synapse.

Lübbert M, Goral RO, Keine C, Thomas C, Guerrero-Given D, Putzke T, Satterfield R, Kamasawa N, Young SM Jr.

Neuron. 2019 Jan 16;101(2):260-273.e6. doi: 10.1016/j.neuron.2018.11.028. Epub 2018 Dec 10.


Ablation of α2δ-1 inhibits cell-surface trafficking of endogenous N-type calcium channels in the pain pathway in vivo.

Nieto-Rostro M, Ramgoolam K, Pratt WS, Kulik A, Dolphin AC.

Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):E12043-E12052. doi: 10.1073/pnas.1811212115. Epub 2018 Nov 28.


Targeting of N-Type Calcium Channels via GABAB-Receptor Activation by α-Conotoxin Vc1.1 Variants Displaying Improved Analgesic Activity.

Cai F, Xu N, Liu Z, Ding R, Yu S, Dong M, Wang S, Shen J, Tae HS, Adams DJ, Zhang X, Dai Q.

J Med Chem. 2018 Nov 21;61(22):10198-10205. doi: 10.1021/acs.jmedchem.8b01343. Epub 2018 Nov 6.


Discovery and optimization of a novel series of pyrazolyltetrahydropyran N-type calcium channel (Cav 2.2) blockers for the treatment of pain.

Wall MJ, Subasinghe NL, Winters MP, Lubin ML, Finley MFA, Qin N, Brandt MR, Neeper MP, Schneider CR, Colburn RW, Flores CM, Sui Z.

Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3780-3783. doi: 10.1016/j.bmcl.2018.10.007. Epub 2018 Oct 12.


Translocatable voltage-gated Ca2+ channel β subunits in α1-β complexes reveal competitive replacement yet no spontaneous dissociation.

Yeon JH, Park CG, Hille B, Suh BC.

Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):E9934-E9943. doi: 10.1073/pnas.1809762115. Epub 2018 Sep 26.


Variation within voltage-gated calcium channel genes and antipsychotic treatment response in a South African first episode schizophrenia cohort.

O'Connell KS, McGregor NW, Malhotra A, Lencz T, Emsley R, Warnich L.

Pharmacogenomics J. 2019 Feb;19(1):109-114. doi: 10.1038/s41397-018-0033-5. Epub 2018 Jul 22.


Proteolytic maturation of α2δ controls the probability of synaptic vesicular release.

Ferron L, Kadurin I, Dolphin AC.

Elife. 2018 Jun 19;7. pii: e37507. doi: 10.7554/eLife.37507.


Lipid-lowering effects of oleanolic acid in hyperlipidemic patients.

Luo HQ, Shen J, Chen CP, Ma X, Lin C, Ouyang Q, Xuan CX, Liu J, Sun HB, Liu J.

Chin J Nat Med. 2018 May;16(5):339-346. doi: 10.1016/S1875-5364(18)30065-7.


Upregulation of N-type calcium channels in the soma of uninjured dorsal root ganglion neurons contributes to neuropathic pain by increasing neuronal excitability following peripheral nerve injury.

Yang J, Xie MX, Hu L, Wang XF, Mai JZ, Li YY, Wu N, Zhang C, Li J, Pang RP, Liu XG.

Brain Behav Immun. 2018 Jul;71:52-65. doi: 10.1016/j.bbi.2018.04.016. Epub 2018 Apr 27.


Validation and bioinformatic analysis of propofol-induced differentially expressed microRNAs in primary cultured neural stem cells.

Li Y, Liu Y, Fan J, Zhou Q, Song X, Peng Z, Qin Z, Tao T.

Gene. 2018 Jul 20;664:90-100. doi: 10.1016/j.gene.2018.04.046. Epub 2018 Apr 19.


CRMP2-Neurofibromin Interface Drives NF1-related Pain.

Moutal A, Sun L, Yang X, Li W, Cai S, Luo S, Khanna R.

Neuroscience. 2018 Jun 15;381:79-90. doi: 10.1016/j.neuroscience.2018.04.002. Epub 2018 Apr 12.

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