Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 61

1.

A microglial cell model for acyl-CoA oxidase 1 deficiency.

Raas Q, Saih FE, Gondcaille C, Trompier D, Hamon Y, Leoni V, Caccia C, Nasser B, Jadot M, Ménétrier F, Lizard G, Cherkaoui-Malki M, Andreoletti P, Savary S.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Oct 10. pii: S1388-1981(18)30324-X. doi: 10.1016/j.bbalip.2018.10.005. [Epub ahead of print]

PMID:
30312667
2.

Safinamide Modulates Striatal Glutamatergic Signaling in a Rat Model of Levodopa-Induced Dyskinesia.

Gardoni F, Morari M, Kulisevsky J, Brugnoli A, Novello S, Pisanò CA, Caccia C, Mellone M, Melloni E, Padoani G, Sosti V, Vailati S, Keywood C.

J Pharmacol Exp Ther. 2018 Dec;367(3):442-451. doi: 10.1124/jpet.118.251645. Epub 2018 Oct 5.

PMID:
30291173
3.

International descriptive and interventional survey for oxycholesterol determination by gas- and liquid-chromatographic methods.

Lütjohann D, Björkhem I, Friedrichs S, Kerksiek A, Geilenkeuser WJ, Lövgren-Sandblom A, Ansorena D, Astiasarán I, Baila-Rueda L, Barriuso B, Bretillon L, Browne RW, Caccia C, Cenarro A, Crick PJ, Fauler G, García-Llatas G, Griffiths WJ, Iuliano L, Lagarda MJ, Leoni V, Lottenberg AM, Matysik S, McDonald J, Rideout TC, Schmitz G, Nunes VS, Wang Y, Zerbinati C, Diczfalusy U, Schött HF.

Biochimie. 2018 Oct;153:26-32. doi: 10.1016/j.biochi.2018.07.016. Epub 2018 Jul 29.

PMID:
30063945
4.

Induction of peroxisomal changes in oligodendrocytes treated with 7-ketocholesterol: Attenuation by α-tocopherol.

Nury T, Sghaier R, Zarrouk A, Ménétrier F, Uzun T, Leoni V, Caccia C, Meddeb W, Namsi A, Sassi K, Mihoubi W, Riedinger JM, Cherkaoui-Malki M, Moreau T, Vejux A, Lizard G.

Biochimie. 2018 Oct;153:181-202. doi: 10.1016/j.biochi.2018.07.009. Epub 2018 Jul 19.

PMID:
30031877
5.

Lipid accumulation in human breast cancer cells injured by iron depletors.

De Bortoli M, Taverna E, Maffioli E, Casalini P, Crisafi F, Kumar V, Caccia C, Polli D, Tedeschi G, Bongarzone I.

J Exp Clin Cancer Res. 2018 Apr 3;37(1):75. doi: 10.1186/s13046-018-0737-z.

6.

Intestinal permeability and Ménière's disease.

Di Berardino F, Zanetti D, Ciusani E, Caccia C, Leoni V, De Grazia U, Filipponi E, Elli L.

Am J Otolaryngol. 2018 Mar - Apr;39(2):153-156. doi: 10.1016/j.amjoto.2017.12.002. Epub 2017 Dec 5.

PMID:
29248204
7.

Safinamide Differentially Modulates In Vivo Glutamate and GABA Release in the Rat Hippocampus and Basal Ganglia.

Morari M, Brugnoli A, Pisanò CA, Novello S, Caccia C, Melloni E, Padoani G, Vailati S, Sardina M.

J Pharmacol Exp Ther. 2018 Feb;364(2):198-206. doi: 10.1124/jpet.117.245100. Epub 2017 Nov 22.

PMID:
29167350
8.

A TSPO ligand prevents mitochondrial sterol accumulation and dysfunction during myocardial ischemia-reperfusion in hypercholesterolemic rats.

Musman J, Paradis S, Panel M, Pons S, Barau C, Caccia C, Leoni V, Ghaleh B, Morin D.

Biochem Pharmacol. 2017 Oct 15;142:87-95. doi: 10.1016/j.bcp.2017.06.125. Epub 2017 Jun 21.

PMID:
28645478
9.

Inhibition of herpes simplex-1 virus replication by 25-hydroxycholesterol and 27-hydroxycholesterol.

Cagno V, Civra A, Rossin D, Calfapietra S, Caccia C, Leoni V, Dorma N, Biasi F, Poli G, Lembo D.

Redox Biol. 2017 Aug;12:522-527. doi: 10.1016/j.redox.2017.03.016. Epub 2017 Mar 23.

10.

MIF/CD74 axis is a target for novel therapies in colon carcinomatosis.

Bozzi F, Mogavero A, Varinelli L, Belfiore A, Manenti G, Caccia C, Volpi CC, Beznoussenko GV, Milione M, Leoni V, Gloghini A, Mironov AA, Leo E, Pilotti S, Pierotti MA, Bongarzone I, Gariboldi M.

J Exp Clin Cancer Res. 2017 Jan 23;36(1):16. doi: 10.1186/s13046-016-0475-z.

11.

Regular treadmill exercise inhibits mitochondrial accumulation of cholesterol and oxysterols during myocardial ischemia-reperfusion in wild-type and ob/ob mice.

Musman J, Pons S, Barau C, Caccia C, Leoni V, Berdeaux A, Ghaleh B, Morin D.

Free Radic Biol Med. 2016 Dec;101:317-324. doi: 10.1016/j.freeradbiomed.2016.10.496. Epub 2016 Oct 28.

PMID:
27989751
12.

Early and brain region-specific decrease of de novo cholesterol biosynthesis in Huntington's disease: A cross-validation study in Q175 knock-in mice.

Shankaran M, Di Paolo E, Leoni V, Caccia C, Ferrari Bardile C, Mohammed H, Di Donato S, Kwak S, Marchionini D, Turner S, Cattaneo E, Valenza M.

Neurobiol Dis. 2017 Feb;98:66-76. doi: 10.1016/j.nbd.2016.11.013. Epub 2016 Nov 30.

PMID:
27913290
13.

In-vivo brain H1-MR-Spectroscopy identification and quantification of 2-hydroxyglutarate in L-2-Hydroxyglutaric aciduria.

Anghileri E, Bertolino N, Salsano E, Antelmi L, Carpinelli P, Castellotti B, Zucca I, Gellera C, Bisogno R, Caccia C, Cuccarini V.

Brain Res. 2016 Oct 1;1648(Pt A):506-511. doi: 10.1016/j.brainres.2016.08.013. Epub 2016 Aug 16.

PMID:
27543339
14.

Mitochondrial dysfunctions in 7-ketocholesterol-treated 158N oligodendrocytes without or with α-tocopherol: Impacts on the cellular profil of tricarboxylic cycle-associated organic acids, long chain saturated and unsaturated fatty acids, oxysterols, cholesterol and cholesterol precursors.

Leoni V, Nury T, Vejux A, Zarrouk A, Caccia C, Debbabi M, Fromont A, Sghaier R, Moreau T, Lizard G.

J Steroid Biochem Mol Biol. 2017 May;169:96-110. doi: 10.1016/j.jsbmb.2016.03.029. Epub 2016 Mar 25.

PMID:
27020660
15.

Cholesterol-loaded nanoparticles ameliorate synaptic and cognitive function in Huntington's disease mice.

Valenza M, Chen JY, Di Paolo E, Ruozi B, Belletti D, Ferrari Bardile C, Leoni V, Caccia C, Brilli E, Di Donato S, Boido MM, Vercelli A, Vandelli MA, Forni F, Cepeda C, Levine MS, Tosi G, Cattaneo E.

EMBO Mol Med. 2015 Dec;7(12):1547-64. doi: 10.15252/emmm.201505413.

16.

4-IPP, a selective MIF inhibitor, causes mitotic catastrophe in thyroid carcinomas.

Varinelli L, Caccia D, Volpi CC, Caccia C, De Bortoli M, Taverna E, Gualeni AV, Leoni V, Gloghini A, Manenti G, Bongarzone I.

Endocr Relat Cancer. 2015 Oct;22(5):759-75. doi: 10.1530/ERC-15-0299. Epub 2015 Jul 23.

PMID:
26206776
17.

PEX7 Mutations Cause Congenital Cataract Retinopathy and Late-Onset Ataxia and Cognitive Impairment: Report of Two Siblings and Review of the Literature.

Nanetti L, Pensato V, Leoni V, Rizzetto M, Caccia C, Taroni F, Mariotti C, Gellera C.

J Clin Neurol. 2015 Apr;11(2):197-9. doi: 10.3988/jcn.2015.11.2.197. No abstract available.

18.

The impairment of cholesterol metabolism in Huntington disease.

Leoni V, Caccia C.

Biochim Biophys Acta. 2015 Aug;1851(8):1095-105. doi: 10.1016/j.bbalip.2014.12.018. Epub 2015 Jan 14. Review.

PMID:
25596342
19.

Somatosensory conduction pathway in spastic paraplegia type 5.

Vanotti A, Nanetti L, Rossi Sebastiano D, Visani E, Duran D, Di Bella D, Sarto E, Caccia C, Leoni V, Taroni F, Mariotti C.

J Clin Neurol. 2014 Oct;10(4):373-4. doi: 10.3988/jcn.2014.10.4.373. Epub 2014 Oct 6. No abstract available.

20.

Study of cholesterol metabolism in Huntington's disease.

Leoni V, Caccia C.

Biochem Biophys Res Commun. 2014 Apr 11;446(3):697-701. doi: 10.1016/j.bbrc.2014.01.188. Epub 2014 Feb 10. Review.

PMID:
24525128
21.

Weight loss intervention for young adults using mobile technology: design and rationale of a randomized controlled trial - Cell Phone Intervention for You (CITY).

Batch BC, Tyson C, Bagwell J, Corsino L, Intille S, Lin PH, Lazenka T, Bennett G, Bosworth HB, Voils C, Grambow S, Sutton A, Bordogna R, Pangborn M, Schwager J, Pilewski K, Caccia C, Burroughs J, Svetkey LP.

Contemp Clin Trials. 2014 Mar;37(2):333-41. doi: 10.1016/j.cct.2014.01.003. Epub 2014 Jan 21. Erratum in: Contemp Clin Trials. 2014 Nov;39(2):351.

22.

Cardioprotection by the TSPO ligand 4'-chlorodiazepam is associated with inhibition of mitochondrial accumulation of cholesterol at reperfusion.

Paradis S, Leoni V, Caccia C, Berdeaux A, Morin D.

Cardiovasc Res. 2013 Jun 1;98(3):420-7. doi: 10.1093/cvr/cvt079. Epub 2013 Apr 3.

23.

Potential diagnostic applications of side chain oxysterols analysis in plasma and cerebrospinal fluid.

Leoni V, Caccia C.

Biochem Pharmacol. 2013 Jul 1;86(1):26-36. doi: 10.1016/j.bcp.2013.03.015. Epub 2013 Mar 28. Review.

PMID:
23541982
24.

Pitfalls in the detection of cholesterol in Huntington's disease models.

Marullo M, Valenza M, Leoni V, Caccia C, Scarlatti C, De Mario A, Zuccato C, Di Donato S, Carafoli E, Cattaneo E.

PLoS Curr. 2012 Oct 11;4:e505886e9a1968. doi: 10.1371/505886e9a1968.

25.

24S-hydroxycholesterol in plasma: a marker of cholesterol turnover in neurodegenerative diseases.

Leoni V, Caccia C.

Biochimie. 2013 Mar;95(3):595-612. doi: 10.1016/j.biochi.2012.09.025. Epub 2012 Oct 3. Review.

PMID:
23041502
26.

Determinants and consequences of adherence to the dietary approaches to stop hypertension diet in African-American and white adults with high blood pressure: results from the ENCORE trial.

Epstein DE, Sherwood A, Smith PJ, Craighead L, Caccia C, Lin PH, Babyak MA, Johnson JJ, Hinderliter A, Blumenthal JA.

J Acad Nutr Diet. 2012 Nov;112(11):1763-73. doi: 10.1016/j.jand.2012.07.007. Epub 2012 Sep 19.

27.

Metabolic consequences of mitochondrial coenzyme A deficiency in patients with PANK2 mutations.

Leoni V, Strittmatter L, Zorzi G, Zibordi F, Dusi S, Garavaglia B, Venco P, Caccia C, Souza AL, Deik A, Clish CB, Rimoldi M, Ciusani E, Bertini E, Nardocci N, Mootha VK, Tiranti V.

Mol Genet Metab. 2012 Mar;105(3):463-71. doi: 10.1016/j.ymgme.2011.12.005. Epub 2011 Dec 14.

28.

Oxysterols as biomarkers in neurodegenerative diseases.

Leoni V, Caccia C.

Chem Phys Lipids. 2011 Sep;164(6):515-24. doi: 10.1016/j.chemphyslip.2011.04.002. Epub 2011 Apr 16. Review.

PMID:
21515244
29.

Effects of the DASH diet alone and in combination with exercise and weight loss on blood pressure and cardiovascular biomarkers in men and women with high blood pressure: the ENCORE study.

Blumenthal JA, Babyak MA, Hinderliter A, Watkins LL, Craighead L, Lin PH, Caccia C, Johnson J, Waugh R, Sherwood A.

Arch Intern Med. 2010 Jan 25;170(2):126-35. doi: 10.1001/archinternmed.2009.470.

30.

Discovery of a novel class of potent coumarin monoamine oxidase B inhibitors: development and biopharmacological profiling of 7-[(3-chlorobenzyl)oxy]-4-[(methylamino)methyl]-2H-chromen-2-one methanesulfonate (NW-1772) as a highly potent, selective, reversible, and orally active monoamine oxidase B inhibitor.

Pisani L, Muncipinto G, Miscioscia TF, Nicolotti O, Leonetti F, Catto M, Caccia C, Salvati P, Soto-Otero R, Mendez-Alvarez E, Passeleu C, Carotti A.

J Med Chem. 2009 Nov 12;52(21):6685-706. doi: 10.1021/jm9010127.

PMID:
19810674
31.

Retinoic acid reduces human neuroblastoma cell migration and invasiveness: effects on DCX, LIS1, neurofilaments-68 and vimentin expression.

Messi E, Florian MC, Caccia C, Zanisi M, Maggi R.

BMC Cancer. 2008 Jan 29;8:30. doi: 10.1186/1471-2407-8-30.

32.

Structures of human monoamine oxidase B complexes with selective noncovalent inhibitors: safinamide and coumarin analogs.

Binda C, Wang J, Pisani L, Caccia C, Carotti A, Salvati P, Edmondson DE, Mattevi A.

J Med Chem. 2007 Nov 15;50(23):5848-52. Epub 2007 Oct 4.

PMID:
17915852
33.

Solid-phase synthesis and insights into structure-activity relationships of safinamide analogues as potent and selective inhibitors of type B monoamine oxidase.

Leonetti F, Capaldi C, Pisani L, Nicolotti O, Muncipinto G, Stefanachi A, Cellamare S, Caccia C, Carotti A.

J Med Chem. 2007 Oct 4;50(20):4909-16. Epub 2007 Sep 7.

PMID:
17824599
34.

Safinamide: from molecular targets to a new anti-Parkinson drug.

Caccia C, Maj R, Calabresi M, Maestroni S, Faravelli L, Curatolo L, Salvati P, Fariello RG.

Neurology. 2006 Oct 10;67(7 Suppl 2):S18-23. Review.

PMID:
17030736
35.

NMDA receptor composition differs among anatomically diverse malformations of cortical development.

Finardi A, Gardoni F, Bassanini S, Lasio G, Cossu M, Tassi L, Caccia C, Taroni F, LoRusso G, Di Luca M, Battaglia G.

J Neuropathol Exp Neurol. 2006 Sep;65(9):883-93.

PMID:
16957582
36.

Hormonal induction of adipogenesis induces Skp2 expression through PI3K and MAPK pathways.

Auld CA, Caccia CD, Morrison RF.

J Cell Biochem. 2007 Jan 1;100(1):204-16.

PMID:
16924675
37.

Schizencephaly: clinical spectrum, epilepsy, and pathogenesis.

Granata T, Freri E, Caccia C, Setola V, Taroni F, Battaglia G.

J Child Neurol. 2005 Apr;20(4):313-8. Review.

PMID:
15921232
38.

Pharmacokinetics and pharmacodynamics of safinamide, a neuroprotectant with antiparkinsonian and anticonvulsant activity.

Marzo A, Dal Bo L, Monti NC, Crivelli F, Ismaili S, Caccia C, Cattaneo C, Fariello RG.

Pharmacol Res. 2004 Jul;50(1):77-85.

PMID:
15082032
39.
40.

Sodium channel activity and sigma binding of 2-aminopropanamide anticonvulsants.

Pevarello P, Bonsignori A, Caccia C, Amici R, McArthur RA, Fariello RG, Salvati P, Varasi M.

Bioorg Med Chem Lett. 1999 Sep 6;9(17):2521-4.

PMID:
10498200
41.

Synthesis and preliminary biological evaluation of new alpha-amino amide anticonvulsants incorporating a dextromethorphan moiety.

Pevarello P, Traquandi G, Bonsignori A, McArthur RA, Maj R, Caccia C, Salvati P, Varasi M.

Bioorg Med Chem Lett. 1999 Jul 5;9(13):1783-8.

PMID:
10406642
42.

Biochemical and electrophysiological studies on the mechanism of action of PNU-151774E, a novel antiepileptic compound.

Salvati P, Maj R, Caccia C, Cervini MA, Fornaretto MG, Lamberti E, Pevarello P, Skeen GA, White HS, Wolf HH, Faravelli L, Mazzanti M, Mancinelli E, Varasi M, Fariello RG.

J Pharmacol Exp Ther. 1999 Mar;288(3):1151-9.

43.

Serotonergic ergoline derivatives.

Mantegani S, Brambilla E, Caccia C, Damiani G, Fornaretto MG, McArthur RA, Varasi M.

Bioorg Med Chem Lett. 1998 May 5;8(9):1117-22.

PMID:
9871719
44.

Synthesis and antihypertensive activity of 2,4-dioxoimidazolidin-1-yl and perhydro-2,4-dioxopyrimidin-1-yl ergoline derivatives.

Mantegani S, Brambilla E, Caccia C, Chiodini L, Ruggieri D, Lamberti E, Di Salle E, Salvati P.

Farmaco. 1998 Apr;53(4):293-304.

PMID:
9658588
45.

Synthesis and in vitro and in vivo evaluation of dopaminergic ergoline derivatives.

Mantegani S, Brambilla E, Caccia C, Di Salle E, Cervini MA, McArthur RA, Traquandi G, Varasi M.

Farmaco. 1998 Jan;53(1):65-72.

PMID:
9543728
46.

Recombinant human IL-2 is cytotoxic to oligodendrocytes after in vitro self aggregation.

Curatolo L, Valsasina B, Caccia C, Raimondi GL, Orsini G, Bianchetti A.

Cytokine. 1997 Oct;9(10):734-9.

PMID:
9344504
47.

Phenylimidazolidin-2-one derivatives as selective 5-HT3 receptor antagonists and refinement of the pharmacophore model for 5-HT3 receptor binding.

Heidempergher F, Pillan A, Pinciroli V, Vaghi F, Arrigoni C, Bolis G, Caccia C, Dho L, McArthur R, Varasi M.

J Med Chem. 1997 Oct 10;40(21):3369-80.

PMID:
9341912
48.

13-Tert-butylergoline derivatives. Assessment of functional serotonergic 5-HT1A component.

Fornaretto MG, Caccia C, Marchi G, Brambilla E, Mantegani S, Post C.

Ann N Y Acad Sci. 1997 May 30;812:226-8. No abstract available.

PMID:
9186752
49.

Structure-activity relationship studies on the 5-HT(1A) receptor affinity of 1-phenyl-4-[omega-(alpha- or beta-tetralinyl)alkyl]piperazines. 4.

Perrone R, Berardi F, Colabufo NA, Leopoldo M, Tortorella V, Fornaretto MG, Caccia C, McArthur RA.

J Med Chem. 1996 Dec 6;39(25):4928-34.

PMID:
8960552
50.

1-aryl-4-[(1-tetralinyl)alkyl]piperazines: alkylamido and alkylamino derivatives. Synthesis, 5-HT1A receptor affinity, and selectivity. 3.

Perrone R, Berardi F, Leopoldo M, Tortorella V, Fornaretto MG, Caccia C, McArthur RA.

J Med Chem. 1996 Aug 2;39(16):3195-202.

PMID:
8759642

Supplemental Content

Loading ...
Support Center