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Items: 1 to 50 of 286

1.

Multifactorial Modeling Reveals a Dominant Role of Wnt Signaling in Lineage Commitment of Human Pluripotent Stem Cells.

Dias TP, Fernandes TG, Diogo MM, Cabral JMS.

Bioengineering (Basel). 2019 Aug 15;6(3). pii: E71. doi: 10.3390/bioengineering6030071.

2.

Economics of Beta-Cell Replacement Therapy.

Bandeiras C, Hwa AJ, Cabral JMS, Ferreira FC, Finkelstein SN, Gabbay RA.

Curr Diab Rep. 2019 Aug 2;19(9):75. doi: 10.1007/s11892-019-1203-9. Review.

PMID:
31375935
3.

Transcriptomic analysis of 3D Cardiac Differentiation of Human Induced Pluripotent Stem Cells Reveals Faster Cardiomyocyte Maturation Compared to 2D Culture.

Branco MA, Cotovio JP, Rodrigues CAV, Vaz SH, Fernandes TG, Moreira LM, Cabral JMS, Diogo MM.

Sci Rep. 2019 Jun 25;9(1):9229. doi: 10.1038/s41598-019-45047-9.

4.

Author Correction: A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip.

Jalili-Firoozinezhad S, Gazzaniga FS, Calamari EL, Camacho DM, Fadel CW, Bein A, Swenor B, Nestor B, Cronce MJ, Tovaglieri A, Levy O, Gregory KE, Breault DT, Cabral JMS, Kasper DL, Novak R, Ingber DE.

Nat Biomed Eng. 2019 Jul;3(7):583. doi: 10.1038/s41551-019-0428-x.

PMID:
31213704
5.

Cultured cell-derived extracellular matrices to enhance the osteogenic differentiation and angiogenic properties of human mesenchymal stem/stromal cells.

Carvalho MS, Silva JC, Cabral JMS, da Silva CL, Vashishth D.

J Tissue Eng Regen Med. 2019 Sep;13(9):1544-1558. doi: 10.1002/term.2907. Epub 2019 Jul 10.

PMID:
31151132
6.

Design Principles for Pluripotent Stem Cell-Derived Organoid Engineering.

Silva TP, Cotovio JP, Bekman E, Carmo-Fonseca M, Cabral JMS, Fernandes TG.

Stem Cells Int. 2019 Apr 18;2019:4508470. doi: 10.1155/2019/4508470. eCollection 2019. Review.

7.

Bringing Stem Cell-Based Therapies for Type 1 Diabetes to the Clinic: Early Insights from Bioprocess Economics and Cost-Effectiveness Analysis.

Bandeiras C, Cabral JMS, Gabbay RA, Finkelstein SN, Ferreira FC.

Biotechnol J. 2019 Aug;14(8):e1800563. doi: 10.1002/biot.201800563. Epub 2019 Jul 8.

PMID:
31127682
8.

A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip.

Jalili-Firoozinezhad S, Gazzaniga FS, Calamari EL, Camacho DM, Fadel CW, Bein A, Swenor B, Nestor B, Cronce MJ, Tovaglieri A, Levy O, Gregory KE, Breault DT, Cabral JMS, Kasper DL, Novak R, Ingber DE.

Nat Biomed Eng. 2019 Jul;3(7):520-531. doi: 10.1038/s41551-019-0397-0. Epub 2019 May 13. Erratum in: Nat Biomed Eng. 2019 Jun 18;:.

PMID:
31086325
9.

Scalable Manufacturing of Human Mesenchymal Stromal Cells in the Vertical-Wheel Bioreactor System: An Experimental and Economic Approach.

de Sousa Pinto D, Bandeiras C, de Almeida Fuzeta M, Rodrigues CAV, Jung S, Hashimura Y, Tseng RJ, Milligan W, Lee B, Ferreira FC, Lobato da Silva C, Cabral JMS.

Biotechnol J. 2019 Aug;14(8):e1800716. doi: 10.1002/biot.201800716. Epub 2019 May 31.

PMID:
30945467
10.

Co-culture cell-derived extracellular matrix loaded electrospun microfibrous scaffolds for bone tissue engineering.

Carvalho MS, Silva JC, Udangawa RN, Cabral JMS, Ferreira FC, da Silva CL, Linhardt RJ, Vashishth D.

Mater Sci Eng C Mater Biol Appl. 2019 Jun;99:479-490. doi: 10.1016/j.msec.2019.01.127. Epub 2019 Jan 30.

PMID:
30889723
11.

Compositional and structural analysis of glycosaminoglycans in cell-derived extracellular matrices.

Silva JC, Carvalho MS, Han X, Xia K, Mikael PE, Cabral JMS, Ferreira FC, Linhardt RJ.

Glycoconj J. 2019 Apr;36(2):141-154. doi: 10.1007/s10719-019-09858-2. Epub 2019 Jan 14.

PMID:
30637588
12.

Modeling biological and economic uncertainty on cell therapy manufacturing: the choice of culture media supplementation.

Bandeiras C, Cabral JM, Finkelstein SN, Ferreira FC.

Regen Med. 2018 Dec;13(8):917-933. doi: 10.2217/rme-2018-0034. Epub 2018 Nov 29.

PMID:
30488770
13.

ATRX promotes maintenance of herpes simplex virus heterochromatin during chromatin stress.

Cabral JM, Oh HS, Knipe DM.

Elife. 2018 Nov 22;7. pii: e40228. doi: 10.7554/eLife.40228.

14.

CD7 CAR T Cells for the Therapy of Acute Myeloid Leukemia.

Gomes-Silva D, Atilla E, Atilla PA, Mo F, Tashiro H, Srinivasan M, Lulla P, Rouce RH, Cabral JMS, Ramos CA, Brenner MK, Mamonkin M.

Mol Ther. 2019 Jan 2;27(1):272-280. doi: 10.1016/j.ymthe.2018.10.001. Epub 2018 Oct 4.

PMID:
30391141
15.

Three-Dimensional Co-culture of Human Hematopoietic Stem/Progenitor Cells and Mesenchymal Stem/Stromal Cells in a Biomimetic Hematopoietic Niche Microenvironment.

Costa MHG, Monteiro TS, Cardoso S, Cabral JMS, Ferreira FC, da Silva CL.

Methods Mol Biol. 2019;2002:101-119. doi: 10.1007/7651_2018_181.

PMID:
30367359
16.

Synergistic effect of extracellularly supplemented osteopontin and osteocalcin on stem cell proliferation, osteogenic differentiation, and angiogenic properties.

Carvalho MS, Cabral JM, da Silva CL, Vashishth D.

J Cell Biochem. 2019 Apr;120(4):6555-6569. doi: 10.1002/jcb.27948. Epub 2018 Oct 25.

PMID:
30362184
17.

Dissolvable Microcarriers Allow Scalable Expansion And Harvesting Of Human Induced Pluripotent Stem Cells Under Xeno-Free Conditions.

Rodrigues AL, Rodrigues CAV, Gomes AR, Vieira SF, Badenes SM, Diogo MM, Cabral JMS.

Biotechnol J. 2019 Apr;14(4):e1800461. doi: 10.1002/biot.201800461. Epub 2018 Nov 12.

PMID:
30320457
18.

Biomimetic matrices for rapidly forming mineralized bone tissue based on stem cell-mediated osteogenesis.

Carvalho MS, Poundarik AA, Cabral JMS, da Silva CL, Vashishth D.

Sci Rep. 2018 Sep 26;8(1):14388. doi: 10.1038/s41598-018-32794-4.

19.

Engineering of Human Mesenchymal Stem/Stromal Cells with Vascular Endothelial Growth Factor-Encoding Minicircles for Angiogenic Ex Vivo Gene Therapy.

Serra J, Alves CPA, Brito L, Monteiro GA, Cabral JMS, Prazeres DMF, da Silva CL.

Hum Gene Ther. 2019 Mar;30(3):316-329. doi: 10.1089/hum.2018.154. Epub 2018 Nov 13.

PMID:
30200778
20.

Successful isolation and ex vivo expansion of human mesenchymal stem/stromal cells obtained from different synovial tissue-derived (biopsy) samples.

Ferro T, Santhagunam A, Madeira C, Salgueiro JB, da Silva CL, Cabral JMS.

J Cell Physiol. 2019 Apr;234(4):3973-3984. doi: 10.1002/jcp.27202. Epub 2018 Aug 26.

PMID:
30146686
21.

Towards Multi-Organoid Systems for Drug Screening Applications.

Miranda CC, Fernandes TG, Diogo MM, Cabral JMS.

Bioengineering (Basel). 2018 Jun 21;5(3). pii: E49. doi: 10.3390/bioengineering5030049. Review.

22.

A scale out approach towards neural induction of human induced pluripotent stem cells for neurodevelopmental toxicity studies.

Miranda CC, Fernandes TG, Pinto SN, Prieto M, Diogo MM, Cabral JMS.

Toxicol Lett. 2018 Sep 15;294:51-60. doi: 10.1016/j.toxlet.2018.05.018. Epub 2018 May 21.

PMID:
29775723
23.

Three-Dimensional Cell-Based Microarrays: Printing Pluripotent Stem Cells into 3D Microenvironments.

Pascoal JF, Fernandes TG, Nierode GJ, Diogo MM, Dordick JS, Cabral JMS.

Methods Mol Biol. 2018;1771:69-81. doi: 10.1007/978-1-4939-7792-5_6.

PMID:
29633205
24.

Biophysical study of human induced Pluripotent Stem Cell-Derived cardiomyocyte structural maturation during long-term culture.

Dias TP, Pinto SN, Santos JI, Fernandes TG, Fernandes F, Diogo MM, Prieto M, Cabral JMS.

Biochem Biophys Res Commun. 2018 May 15;499(3):611-617. doi: 10.1016/j.bbrc.2018.03.198. Epub 2018 Mar 30.

PMID:
29601816
25.

Modeling radiation injury-induced cell death and countermeasure drug responses in a human Gut-on-a-Chip.

Jalili-Firoozinezhad S, Prantil-Baun R, Jiang A, Potla R, Mammoto T, Weaver JC, Ferrante TC, Kim HJ, Cabral JMS, Levy O, Ingber DE.

Cell Death Dis. 2018 Feb 14;9(2):223. doi: 10.1038/s41419-018-0304-8.

26.

Regenerative Medicine Manufacturing.

Cabral JMS, Palecek SP.

Biotechnol J. 2018 Feb;13(2). doi: 10.1002/biot.201800026. No abstract available.

PMID:
29392889
27.

A Fully-Closed and Automated Hollow Fiber Bioreactor for Clinical-Grade Manufacturing of Human Mesenchymal Stem/Stromal Cells.

Mizukami A, de Abreu Neto MS, Moreira F, Fernandes-Platzgummer A, Huang YF, Milligan W, Cabral JMS, da Silva CL, Covas DT, Swiech K.

Stem Cell Rev Rep. 2018 Feb;14(1):141-143. doi: 10.1007/s12015-017-9787-4. No abstract available.

PMID:
29188439
28.

Hematopoietic Niche - Exploring Biomimetic Cues to Improve the Functionality of Hematopoietic Stem/Progenitor Cells.

Costa MHG, de Soure AM, Cabral JMS, Ferreira FC, da Silva CL.

Biotechnol J. 2018 Feb;13(2). doi: 10.1002/biot.201700088. Epub 2017 Dec 28. Review.

PMID:
29178199
29.

Tonic 4-1BB Costimulation in Chimeric Antigen Receptors Impedes T Cell Survival and Is Vector-Dependent.

Gomes-Silva D, Mukherjee M, Srinivasan M, Krenciute G, Dakhova O, Zheng Y, Cabral JMS, Rooney CM, Orange JS, Brenner MK, Mamonkin M.

Cell Rep. 2017 Oct 3;21(1):17-26. doi: 10.1016/j.celrep.2017.09.015.

30.

Tridimensional configurations of human mesenchymal stem/stromal cells to enhance cell paracrine potential towards wound healing processes.

Costa MHG, McDevitt TC, Cabral JMS, da Silva CL, Ferreira FC.

J Biotechnol. 2017 Nov 20;262:28-39. doi: 10.1016/j.jbiotec.2017.09.020. Epub 2017 Sep 28.

PMID:
28965974
31.

Allogeneic cell therapy manufacturing: process development technologies and facility design options.

Abbasalizadeh S, Pakzad M, Cabral JMS, Baharvand H.

Expert Opin Biol Ther. 2017 Oct;17(10):1201-1219. doi: 10.1080/14712598.2017.1354982. Epub 2017 Jul 20. Review.

PMID:
28699788
32.

Defined and Scalable Differentiation of Human Oligodendrocyte Precursors from Pluripotent Stem Cells in a 3D Culture System.

Rodrigues GMC, Gaj T, Adil MM, Wahba J, Rao AT, Lorbeer FK, Kulkarni RU, Diogo MM, Cabral JMS, Miller EW, Hockemeyer D, Schaffer DV.

Stem Cell Reports. 2017 Jun 6;8(6):1770-1783. doi: 10.1016/j.stemcr.2017.04.027. Epub 2017 May 25.

33.

Cultivation-based strategies to find efficient marine biocatalysts.

Rodrigues CJC, Pereira RFS, Fernandes P, Cabral JMS, de Carvalho CCCR.

Biotechnol J. 2017 Jul;12(7). doi: 10.1002/biot.201700036. Epub 2017 Apr 4.

PMID:
28294564
34.

Acellular Urethra Bioscaffold: Decellularization of Whole Urethras for Tissue Engineering Applications.

Simões IN, Vale P, Soker S, Atala A, Keller D, Noiva R, Carvalho S, Peleteiro C, Cabral JM, Eberli D, da Silva CL, Baptista PM.

Sci Rep. 2017 Feb 6;7:41934. doi: 10.1038/srep41934.

35.

Development of novel replication-defective lymphocytic choriomeningitis virus vectors expressing SIV antigens.

Penaloza MacMaster P, Shields JL, Alayo QA, Cabral C, Jimenez J, Mondesir J, Chandrashekar A, Cabral JM, Lim M, Iampietro MJ, Provine NM, Bricault CA, Seaman M, Orlinger K, Aspoeck A, Fuhrmann G, Lilja AE, Monath T, Mangeat B, Pinschewer DD, Barouch DH.

Vaccine. 2017 Jan 3;35(1):1-9. doi: 10.1016/j.vaccine.2016.11.063. Epub 2016 Nov 26.

36.

Scaling up a chemically-defined aggregate-based suspension culture system for neural commitment of human pluripotent stem cells.

Miranda CC, Fernandes TG, Diogo MM, Cabral JM.

Biotechnol J. 2016 Dec;11(12):1628-1638. doi: 10.1002/biot.201600446. Epub 2016 Nov 17.

PMID:
27754603
37.

Scalable microcarrier-based manufacturing of mesenchymal stem/stromal cells.

de Soure AM, Fernandes-Platzgummer A, da Silva CL, Cabral JM.

J Biotechnol. 2016 Oct 20;236:88-109. doi: 10.1016/j.jbiotec.2016.08.007. Epub 2016 Aug 12. Review.

PMID:
27527397
38.

Microcarrier-based platforms for in vitro expansion and differentiation of human pluripotent stem cells in bioreactor culture systems.

Badenes SM, Fernandes TG, Rodrigues CAV, Diogo MM, Cabral JMS.

J Biotechnol. 2016 Sep 20;234:71-82. doi: 10.1016/j.jbiotec.2016.07.023. Epub 2016 Jul 29. Review.

PMID:
27480342
39.

Trisomy 21 consistently activates the interferon response.

Sullivan KD, Lewis HC, Hill AA, Pandey A, Jackson LP, Cabral JM, Smith KP, Liggett LA, Gomez EB, Galbraith MD, DeGregori J, Espinosa JM.

Elife. 2016 Jul 29;5. pii: e16220. doi: 10.7554/eLife.16220.

40.

Integrated culture platform based on a human platelet lysate supplement for the isolation and scalable manufacturing of umbilical cord matrix-derived mesenchymal stem/stromal cells.

de Soure AM, Fernandes-Platzgummer A, Moreira F, Lilaia C, Liu SH, Ku CP, Huang YF, Milligan W, Cabral JMS, da Silva CL.

J Tissue Eng Regen Med. 2017 May;11(5):1630-1640. doi: 10.1002/term.2200. Epub 2016 Jul 22.

PMID:
27444977
41.

Clinical-Grade Manufacturing of Therapeutic Human Mesenchymal Stem/Stromal Cells in Microcarrier-Based Culture Systems.

Fernandes-Platzgummer A, Carmelo JG, da Silva CL, Cabral JM.

Methods Mol Biol. 2016;1416:375-88. doi: 10.1007/978-1-4939-3584-0_22.

PMID:
27236684
42.

Stirred tank bioreactor culture combined with serum-/xenogeneic-free culture medium enables an efficient expansion of umbilical cord-derived mesenchymal stem/stromal cells.

Mizukami A, Fernandes-Platzgummer A, Carmelo JG, Swiech K, Covas DT, Cabral JM, da Silva CL.

Biotechnol J. 2016 Aug;11(8):1048-59. doi: 10.1002/biot.201500532. Epub 2016 Jun 13.

PMID:
27168373
43.

Correction: Defined Essential 8™ Medium and Vitronectin Efficiently Support Scalable Xeno-Free Expansion of Human Induced Pluripotent Stem Cells in Stirred Microcarrier Culture Systems.

Badenes SM, Fernandes TG, Cordeiro CS, Boucher S, Kuninger D, Vemuri MC, Diogo MM, Cabral JM.

PLoS One. 2016 May 5;11(5):e0155296. doi: 10.1371/journal.pone.0155296. eCollection 2016.

44.

SHOULD FNA BE PERFORMED IN PATIENTS WITH A MULTINODULAR GOITER AND COMPRESSIVE SYMPTOMS?

Manuel DC, Betancourt JL, Puthanveedu ND, Kachur S, Williams SF, Cabral JM, Villabona CV, Jose TC.

Endocr Pract. 2016 Aug;22(8):970-3. doi: 10.4158/EP151149.OR. Epub 2016 Apr 4.

PMID:
27042747
45.

Defined Essential 8™ Medium and Vitronectin Efficiently Support Scalable Xeno-Free Expansion of Human Induced Pluripotent Stem Cells in Stirred Microcarrier Culture Systems.

Badenes SM, Fernandes TG, Cordeiro CS, Boucher S, Kuninger D, Vemuri MC, Diogo MM, Cabral JM.

PLoS One. 2016 Mar 21;11(3):e0151264. doi: 10.1371/journal.pone.0151264. eCollection 2016. Erratum in: PLoS One. 2016;11(5):e0155296.

46.

Extracellular matrix microarrays to study inductive signaling for endoderm specification.

Malta DFB, Reticker-Flynn NE, da Silva CL, Cabral JMS, Fleming HE, Zaret KS, Bhatia SN, Underhill GH.

Acta Biomater. 2016 Apr 1;34:30-40. doi: 10.1016/j.actbio.2016.02.014. Epub 2016 Feb 12.

47.

Role of epithelial ion transports in inflammatory bowel disease.

Magalhães D, Cabral JM, Soares-da-Silva P, Magro F.

Am J Physiol Gastrointest Liver Physiol. 2016 Apr 1;310(7):G460-76. doi: 10.1152/ajpgi.00369.2015. Epub 2016 Jan 7. Review.

48.

Amine neurotransmitters, inflammation and epithelial sodium transport.

Soares-da-Silva P, Cabral JM, Magalhães D, Fraga S, Magro F.

Exp Physiol. 2016 Apr;101(4):459-64. doi: 10.1113/EP085284. Epub 2015 Dec 14. Review.

49.

Intracoronary Delivery of Human Mesenchymal/Stromal Stem Cells: Insights from Coronary Microcirculation Invasive Assessment in a Swine Model.

Fiarresga A, Mata MF, Cavaco-Gonçalves S, Selas M, Simões IN, Oliveira E, Carrapiço B, Cardim N, Cabral JM, Ferreira RC, da Silva CL.

PLoS One. 2015 Oct 19;10(10):e0139870. doi: 10.1371/journal.pone.0139870. eCollection 2015.

50.

Scaling up the ex vivo expansion of human circulating CD34(+)progenitor cells with upregulation of angiogenic and anti-inflammatory potential.

Mata MF, Lopes JP, Ishikawa M, Alaiti MA, Cabral JM, da Silva CL, Costa MA.

Cytotherapy. 2015 Dec;17(12):1777-84. doi: 10.1016/j.jcyt.2015.09.003. Epub 2015 Oct 21.

PMID:
26475753

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