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Items: 23


Folate and colorectal cancer in rodents: a model of DNA repair deficiency.

Rosati R, Ma H, Cabelof DC.

J Oncol. 2012;2012:105949. doi: 10.1155/2012/105949. Epub 2012 Oct 9.


Aging alters folate homeostasis and DNA damage response in colon.

Simon KW, Ma H, Dombkowski AA, Cabelof DC.

Mech Ageing Dev. 2012 Feb-Mar;133(2-3):75-82. doi: 10.1016/j.mad.2012.01.003. Epub 2012 Jan 25.


Down syndrome as a model of DNA polymerase beta haploinsufficiency and accelerated aging.

Patterson D, Cabelof DC.

Mech Ageing Dev. 2012 Apr;133(4):133-7. doi: 10.1016/j.mad.2011.10.001. Epub 2011 Oct 12. Review.


Haploinsufficiency in mouse models of DNA repair deficiency: modifiers of penetrance.

Cabelof DC.

Cell Mol Life Sci. 2012 Mar;69(5):727-40. doi: 10.1007/s00018-011-0839-7. Epub 2011 Sep 28. Review.


Folate deficiency regulates expression of DNA polymerase β in response to oxidative stress.

Unnikrishnan A, Prychitko TM, Patel HV, Chowdhury ME, Pilling AB, Ventrella-Lucente LF, Papakonstantinou EV, Cabelof DC, Heydari AR.

Free Radic Biol Med. 2011 Jan 15;50(2):270-80. doi: 10.1016/j.freeradbiomed.2010.11.003. Epub 2010 Nov 8.


Folate deficiency provides protection against colon carcinogenesis in DNA polymerase beta haploinsufficient mice.

Ventrella-Lucente LF, Unnikrishnan A, Pilling AB, Patel HV, Kushwaha D, Dombkowski AA, Schmelz EM, Cabelof DC, Heydari AR.

J Biol Chem. 2010 Jun 18;285(25):19246-58. doi: 10.1074/jbc.M109.069807. Epub 2010 Apr 19.


Transcriptional profiling of the age-related response to genotoxic stress points to differential DNA damage response with age.

Simon K, Mukundan A, Dewundara S, Van Remmen H, Dombkowski AA, Cabelof DC.

Mech Ageing Dev. 2009 Sep;130(9):637-47. doi: 10.1016/j.mad.2009.07.007. Epub 2009 Aug 11.


Mutational spectrum at GATA1 provides insights into mutagenesis and leukemogenesis in Down syndrome.

Cabelof DC, Patel HV, Chen Q, van Remmen H, Matherly LH, Ge Y, Taub JW.

Blood. 2009 Sep 24;114(13):2753-63. doi: 10.1182/blood-2008-11-190330. Epub 2009 Jul 24.


Oxidative stress alters base excision repair pathway and increases apoptotic response in apurinic/apyrimidinic endonuclease 1/redox factor-1 haploinsufficient mice.

Unnikrishnan A, Raffoul JJ, Patel HV, Prychitko TM, Anyangwe N, Meira LB, Friedberg EC, Cabelof DC, Heydari AR.

Free Radic Biol Med. 2009 Jun 1;46(11):1488-99. doi: 10.1016/j.freeradbiomed.2009.02.021. Epub 2009 Mar 3.


Rodent intestinal folate transporters (SLC46A1): secondary structure, functional properties, and response to dietary folate restriction.

Qiu A, Min SH, Jansen M, Malhotra U, Tsai E, Cabelof DC, Matherly LH, Zhao R, Akabas MH, Goldman ID.

Am J Physiol Cell Physiol. 2007 Nov;293(5):C1669-78. Epub 2007 Sep 26.


A screen for suppressors of gross chromosomal rearrangements identifies a conserved role for PLP in preventing DNA lesions.

Kanellis P, Gagliardi M, Banath JP, Szilard RK, Nakada S, Galicia S, Sweeney FD, Cabelof DC, Olive PL, Durocher D.

PLoS Genet. 2007 Aug;3(8):e134.


Aging and base excision repair: in need of a comprehensive approach.

Cabelof DC.

DNA Repair (Amst). 2007 Oct 1;6(10):1399-402. Epub 2007 Jul 31. No abstract available.


Haploinsufficiency in DNA polymerase beta increases cancer risk with age and alters mortality rate.

Cabelof DC, Ikeno Y, Nyska A, Busuttil RA, Anyangwe N, Vijg J, Matherly LH, Tucker JD, Wilson SH, Richardson A, Heydari AR.

Cancer Res. 2006 Aug 1;66(15):7460-5.


Age-related loss of the DNA repair response following exposure to oxidative stress.

Cabelof DC, Raffoul JJ, Ge Y, Van Remmen H, Matherly LH, Heydari AR.

J Gerontol A Biol Sci Med Sci. 2006 May;61(5):427-34.


A sensitive biochemical assay for the detection of uracil.

Cabelof DC, Nakamura J, Heydari AR.

Environ Mol Mutagen. 2006 Jan;47(1):31-7.


Structure and regulation of the murine reduced folate carrier gene: identification of four noncoding exons and promoters and regulation by dietary folates.

Liu M, Ge Y, Cabelof DC, Aboukameel A, Heydari AR, Mohammad R, Matherly LH.

J Biol Chem. 2005 Feb 18;280(7):5588-97. Epub 2004 Dec 3.


Imbalanced base excision repair in response to folate deficiency is accelerated by polymerase beta haploinsufficiency.

Cabelof DC, Raffoul JJ, Nakamura J, Kapoor D, Abdalla H, Heydari AR.

J Biol Chem. 2004 Aug 27;279(35):36504-13. Epub 2004 Jun 24.


Apurinic/apyrimidinic endonuclease (APE/REF-1) haploinsufficient mice display tissue-specific differences in DNA polymerase beta-dependent base excision repair.

Raffoul JJ, Cabelof DC, Nakamura J, Meira LB, Friedberg EC, Heydari AR.

J Biol Chem. 2004 Apr 30;279(18):18425-33. Epub 2004 Feb 18.


Base excision repair deficiency caused by polymerase beta haploinsufficiency: accelerated DNA damage and increased mutational response to carcinogens.

Cabelof DC, Guo Z, Raffoul JJ, Sobol RW, Wilson SH, Richardson A, Heydari AR.

Cancer Res. 2003 Sep 15;63(18):5799-807.


Caloric restriction promotes genomic stability by induction of base excision repair and reversal of its age-related decline.

Cabelof DC, Yanamadala S, Raffoul JJ, Guo Z, Soofi A, Heydari AR.

DNA Repair (Amst). 2003 Mar 1;2(3):295-307.


Induction of DNA polymerase beta-dependent base excision repair in response to oxidative stress in vivo.

Cabelof DC, Raffoul JJ, Yanamadala S, Guo Z, Heydari AR.

Carcinogenesis. 2002 Sep;23(9):1419-25.


Attenuation of DNA polymerase beta-dependent base excision repair and increased DMS-induced mutagenicity in aged mice.

Cabelof DC, Raffoul JJ, Yanamadala S, Ganir C, Guo Z, Heydari AR.

Mutat Res. 2002 Mar 20;500(1-2):135-45.


Preventing infection from foodborne pathogens in liver transplant patients.

Cabelof DC.

J Am Diet Assoc. 1994 Oct;94(10):1140-4. Review.


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