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Items: 1 to 50 of 69

1.

An assay for screening xenobiotics for inhibition of rat thyroid gland peroxidase activity.

Price RJ, Burch R, Chatham LR, Higgins LG, Currie RA, Lake BG.

Xenobiotica. 2019 Jun 19:1-5. doi: 10.1080/00498254.2019.1629044. [Epub ahead of print]

PMID:
31180273
2.

Cardiovascular Effects and Molecular Mechanisms of Bisphenol A and Its Metabolite MBP in Zebrafish.

Brown AR, Green JM, Moreman J, Gunnarsson LM, Mourabit S, Ball J, Winter MJ, Trznadel M, Correia A, Hacker C, Perry A, Wood ME, Hetheridge MJ, Currie RA, Tyler CR.

Environ Sci Technol. 2019 Jan 2;53(1):463-474. doi: 10.1021/acs.est.8b04281. Epub 2018 Dec 20.

3.

The benefits and challenges of opening toxicology control data.

Currie RA, Dodds L.

Toxicol Res (Camb). 2017 Jul 7;6(5):578-579. doi: 10.1039/c7tx00071e. eCollection 2017 Sep 1. Review.

4.

Dose-dependent effects on rat liver miRNAs 200a/b and 429: potential early biomarkers of liver carcinogenesis.

Plummer SM, Wright J, Currie RA.

Toxicol Rep. 2018 Feb 19;5:309-313. doi: 10.1016/j.toxrep.2018.02.004. eCollection 2018.

5.

Sedaxane-Use of Nuclear Receptor Transactivation Assays, Toxicogenomics, and Toxicokinetics as Part of a Mode of Action Framework for Rodent Liver Tumors.

Peffer RC, Cowie DE, Currie RA, Minnema DJ.

Toxicol Sci. 2018 Apr 1;162(2):582-598. doi: 10.1093/toxsci/kfx281.

PMID:
29244179
6.

The nematode Caenorhabditis elegans as a tool to predict chemical activity on mammalian development and identify mechanisms influencing toxicological outcome.

Harlow PH, Perry SJ, Widdison S, Daniels S, Bondo E, Lamberth C, Currie RA, Flemming AJ.

Sci Rep. 2016 Mar 18;6:22965. doi: 10.1038/srep22965.

7.

Phenobarbital and propiconazole toxicogenomic profiles in mice show major similarities consistent with the key role that constitutive androstane receptor (CAR) activation plays in their mode of action.

Currie RA, Peffer RC, Goetz AK, Omiecinski CJ, Goodman JI.

Toxicology. 2014 Jul 3;321:80-8. doi: 10.1016/j.tox.2014.03.003. Epub 2014 Mar 24.

8.

A metabolomics investigation of non-genotoxic carcinogenicity in the rat.

Ament Z, Waterman CL, West JA, Waterfield C, Currie RA, Wright J, Griffin JL.

J Proteome Res. 2013 Dec 6;12(12):5775-90. doi: 10.1021/pr4007766. Epub 2013 Nov 7.

9.

Time and dose-dependent effects of phenobarbital on the rat liver miRNAome.

Koufaris C, Wright J, Osborne M, Currie RA, Gooderham NJ.

Toxicology. 2013 Dec 15;314(2-3):247-53. doi: 10.1016/j.tox.2013.10.004. Epub 2013 Oct 21.

10.

Hepatic microRNA profiles offer predictive and mechanistic insights after exposure to genotoxic and epigenetic hepatocarcinogens.

Koufaris C, Wright J, Currie RA, Gooderham NJ.

Toxicol Sci. 2012 Aug;128(2):532-43. doi: 10.1093/toxsci/kfs170. Epub 2012 May 12.

11.

Spiroindolines identify the vesicular acetylcholine transporter as a novel target for insecticide action.

Sluder A, Shah S, Cassayre J, Clover R, Maienfisch P, Molleyres LP, Hirst EA, Flemming AJ, Shi M, Cutler P, Stanger C, Roberts RS, Hughes DJ, Flury T, Robinson MP, Hillesheim E, Pitterna T, Cederbaum F, Worthington PA, Crossthwaite AJ, Windass JD, Currie RA, Earley FG.

PLoS One. 2012;7(5):e34712. doi: 10.1371/journal.pone.0034712. Epub 2012 May 1.

12.

Toxicogenomics: the challenges and opportunities to identify biomarkers, signatures and thresholds to support mode-of-action.

Currie RA.

Mutat Res. 2012 Aug 15;746(2):97-103. doi: 10.1016/j.mrgentox.2012.03.002. Epub 2012 Mar 13.

PMID:
22445948
13.

Application of a Bayesian deconvolution approach for high-resolution (1)H NMR spectra to assessing the metabolic effects of acute phenobarbital exposure in liver tissue.

Rubtsov DV, Waterman C, Currie RA, Waterfield C, Salazar JD, Wright J, Griffin JL.

Anal Chem. 2010 Jun 1;82(11):4479-85. doi: 10.1021/ac100344m.

PMID:
20446676
14.

An integrated functional genomic study of acute phenobarbital exposure in the rat.

Waterman CL, Currie RA, Cottrell LA, Dow J, Wright J, Waterfield CJ, Griffin JL.

BMC Genomics. 2010 Jan 6;11:9. doi: 10.1186/1471-2164-11-9.

15.

Exocrine pancreas trans-differentiation to hepatocytes--a physiological response to elevated glucocorticoid in vivo.

Wallace K, Marek CJ, Currie RA, Wright MC.

J Steroid Biochem Mol Biol. 2009 Aug;116(1-2):76-85. doi: 10.1016/j.jsbmb.2009.05.002. Epub 2009 May 13.

PMID:
19446026
16.

Mouse liver effects of cyproconazole, a triazole fungicide: role of the constitutive androstane receptor.

Peffer RC, Moggs JG, Pastoor T, Currie RA, Wright J, Milburn G, Waechter F, Rusyn I.

Toxicol Sci. 2007 Sep;99(1):315-25. Epub 2007 Jun 8.

PMID:
17557908
17.

Emerging evidence for the interrelationship of xenobiotic exposure and circadian rhythms: a review.

Lim FL, Currie RA, Orphanides G, Moggs JG.

Xenobiotica. 2006 Oct-Nov;36(10-11):1140-51. Review.

PMID:
17118921
18.

Mapping molecular responses to xenoestrogens through Gene Ontology and pathway analysis of toxicogenomic data.

Currie RA, Orphanides G, Moggs JG.

Reprod Toxicol. 2005 Sep-Oct;20(3):433-40.

PMID:
15964738
19.

Gene ontology mapping as an unbiased method for identifying molecular pathways and processes affected by toxicant exposure: application to acute effects caused by the rodent non-genotoxic carcinogen diethylhexylphthalate.

Currie RA, Bombail V, Oliver JD, Moore DJ, Lim FL, Gwilliam V, Kimber I, Chipman K, Moggs JG, Orphanides G.

Toxicol Sci. 2005 Aug;86(2):453-69. Epub 2005 May 18.

PMID:
15901911
20.

E2A-PBX1 interacts directly with the KIX domain of CBP/p300 in the induction of proliferation in primary hematopoietic cells.

Bayly R, Chuen L, Currie RA, Hyndman BD, Casselman R, Blobel GA, LeBrun DP.

J Biol Chem. 2004 Dec 31;279(53):55362-71. Epub 2004 Oct 26.

21.

Histone deacetylase inhibition is associated with transcriptional repression of the Hmga2 gene.

Ferguson M, Henry PA, Currie RA.

Nucleic Acids Res. 2003 Jun 15;31(12):3123-33.

22.

The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB.

Biondi RM, Kieloch A, Currie RA, Deak M, Alessi DR.

EMBO J. 2001 Aug 15;20(16):4380-90.

23.

Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities.

Dowler S, Currie RA, Campbell DG, Deak M, Kular G, Downes CP, Alessi DR.

Biochem J. 2000 Oct 1;351(Pt 1):19-31.

24.

Mdm2 binding to a conformationally sensitive domain on p53 can be modulated by RNA.

Burch LR, Midgley CA, Currie RA, Lane DP, Hupp TR.

FEBS Lett. 2000 Apr 21;472(1):93-8.

25.

Identification of a pocket in the PDK1 kinase domain that interacts with PIF and the C-terminal residues of PKA.

Biondi RM, Cheung PC, Casamayor A, Deak M, Currie RA, Alessi DR.

EMBO J. 2000 Mar 1;19(5):979-88.

26.

DAPP1: a dual adaptor for phosphotyrosine and 3-phosphoinositides.

Dowler S, Currie RA, Downes CP, Alessi DR.

Biochem J. 1999 Aug 15;342 ( Pt 1):7-12.

27.

Characterisation of a plant 3-phosphoinositide-dependent protein kinase-1 homologue which contains a pleckstrin homology domain.

Deak M, Casamayor A, Currie RA, Downes CP, Alessi DR.

FEBS Lett. 1999 May 28;451(3):220-6.

28.

Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1.

Currie RA, Walker KS, Gray A, Deak M, Casamayor A, Downes CP, Cohen P, Alessi DR, Lucocq J.

Biochem J. 1999 Feb 1;337 ( Pt 3):575-83.

29.

Lipid signalling.

Downes CP, Currie RA.

Curr Biol. 1998 Dec 3;8(24):R865-7. Review. No abstract available.

30.
32.
33.
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39.

The integration of existing specialized clinical information systems into a computer-based patient record.

Currie RA, Stevens DP.

J AHIMA. 1993 Sep;64(9):60, 62-3. No abstract available.

PMID:
10128939
40.
42.

Regulation of kappa immunoglobulin gene transcription in vitro.

Currie RA.

Nucleic Acids Res. 1990 May 25;18(10):2987-92.

43.
44.

A human lymphoid-specific transcription factor that activates immunoglobulin genes is a homoeobox protein.

Scheidereit C, Cromlish JA, Gerster T, Kawakami K, Balmaceda CG, Currie RA, Roeder RG.

Nature. 1988 Dec 8;336(6199):551-7.

PMID:
2904654
45.

Regulation of epidermal growth factor receptors by glucocorticoids during the cell cycle in HeLa S3 cells.

Fanger BO, Currie RA, Cidlowski JA.

Arch Biochem Biophys. 1986 Aug 15;249(1):116-25.

PMID:
3017217
46.

The physicochemical nature of 37 degrees C cytoplasmic glucocorticoid receptors in HeLa S3 cells.

Currie RA, Cidlowski JA.

J Steroid Biochem. 1984 Dec;21(6):717-26.

PMID:
6527536
47.

Comparison of pyridoxal phosphate and 0.4 M KCl-extracted nuclear glucocorticoid receptors in HeLa S3 cells.

Currie RA, Budziak TE, Cidlowski JA.

Arch Biochem Biophys. 1983 Sep;225(2):906-15.

PMID:
6625614
48.

Determination of 2-chloroethanol in honey, beeswax, and pollen.

Bruns GW, Currie RA.

J Assoc Off Anal Chem. 1983 May;66(3):659-62.

PMID:
6863187
49.

Pyridoxal phosphate blocks aggregation of molybdate treated glucocorticoid receptors in HeLa S3 cells.

Cidlowski JA, Currie RA.

J Steroid Biochem. 1982 Sep;17(3):277-80.

PMID:
7132345
50.

Identification of modified forms of human glucocorticoid receptors during the cell cycle.

Currie RA, Cidlowski JA.

Endocrinology. 1982 Jun;110(6):2192-4.

PMID:
7075556

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