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Items: 1 to 50 of 149

1.

CD39 and CD73 in the aortic valve-biochemical and immunohistochemical analysis in valve cell populations and its changes in valve mineralization.

Kaniewska-Bednarczuk E, Kutryb-Zajac B, Sarathchandra P, Pelikant-Malecka I, Sielicka A, Piotrowska I, Slominska EM, Chester AH, Yacoub MH, Smolenski RT.

Cardiovasc Pathol. 2018 Sep - Oct;36:53-63. doi: 10.1016/j.carpath.2018.05.008. Epub 2018 Jun 7.

PMID:
30056298
2.

Nitric oxide and pulmonary arterial hypertension.

Chester AH, Yacoub MH, Moncada S.

Glob Cardiol Sci Pract. 2017 Jun 30;2017(2):14. doi: 10.21542/gcsp.2017.14. Review.

3.

Raman spectroscopy imaging reveals interplay between atherosclerosis and medial calcification in the human aorta.

You AYF, Bergholt MS, St-Pierre JP, Kit-Anan W, Pence IJ, Chester AH, Yacoub MH, Bertazzo S, Stevens MM.

Sci Adv. 2017 Dec 6;3(12):e1701156. doi: 10.1126/sciadv.1701156. eCollection 2017 Dec.

4.

Controlling the Uptake and Regulating the Release of Nitric Oxide in Microporous Solids.

Haikal RR, Hua C, Perry JJ 4th, O'Nolan D, Syed I, Kumar A, Chester AH, Zaworotko MJ, Yacoub MH, Alkordi MH.

ACS Appl Mater Interfaces. 2017 Dec 20;9(50):43520-43528. doi: 10.1021/acsami.7b15095. Epub 2017 Dec 11.

PMID:
29182298
5.

Tissue Engineering-Bridging the Gap.

Chester AH.

J Cardiovasc Transl Res. 2017 Apr;10(2):91-92. doi: 10.1007/s12265-017-9749-x. No abstract available.

PMID:
28500574
6.

A Strategy to Enhance Secretion of Extracellular Matrix Components by Stem Cells: Relevance to Tissue Engineering.

Krishnamoorthy N, Tseng YT, Gajendrarao P, Sarathchandra P, McCormack A, Carubelli I, Sohier J, Latif N, Chester AH, Yacoub MH.

Tissue Eng Part A. 2018 Jan;24(1-2):145-156. doi: 10.1089/ten.TEA.2017.0060. Epub 2017 Jul 19.

7.

Chemical and biological assessment of metal organic frameworks (MOFs) in pulmonary cells and in an acute in vivo model: relevance to pulmonary arterial hypertension therapy.

Mohamed NA, Davies RP, Lickiss PD, Ahmetaj-Shala B, Reed DM, Gashaw HH, Saleem H, Freeman GR, George PM, Wort SJ, Morales-Cano D, Barreira B, Tetley TD, Chester AH, Yacoub MH, Kirkby NS, Moreno L, Mitchell JA.

Pulm Circ. 2017 Jul-Sep;7(3):643-653. doi: 10.1177/2045893217710224. Epub 2017 Jun 27.

8.

Aortic calcified particles modulate valvular endothelial and interstitial cells.

van Engeland NCA, Bertazzo S, Sarathchandra P, McCormack A, Bouten CVC, Yacoub MH, Chester AH, Latif N.

Cardiovasc Pathol. 2017 May - Jun;28:36-45. doi: 10.1016/j.carpath.2017.02.006. Epub 2017 Mar 3.

9.

Hypoxia-mediated regulation of the secretory properties of mitral valve interstitial cells.

Salhiyyah K, Sarathchandra P, Latif N, Yacoub MH, Chester AH.

Am J Physiol Heart Circ Physiol. 2017 Jul 1;313(1):H14-H23. doi: 10.1152/ajpheart.00720.2016. Epub 2017 Mar 17.

10.

Oxidized low-density lipoproteins enhance expression and activity of CD39 and CD73 in the human aortic valve endothelium.

Kaniewska-Bednarczuk E, Mielcarek M, Chester AH, Slominska EM, Yacoub MH, Smolenski RT.

Nucleosides Nucleotides Nucleic Acids. 2016 Dec;35(10-12):713-719.

11.

Effect of Side-Specific Valvular Shear Stress on the Content of Extracellular Matrix in Aortic Valves.

Mongkoldhumrongkul N, Latif N, Yacoub MH, Chester AH.

Cardiovasc Eng Technol. 2018 Jun;9(2):151-157. doi: 10.1007/s13239-016-0280-z. Epub 2016 Oct 5.

12.

A New NO-Releasing Nanoformulation for the Treatment of Pulmonary Arterial Hypertension.

Mohamed NA, Ahmetaj-Shala B, Duluc L, Mackenzie LS, Kirkby NS, Reed DM, Lickiss PD, Davies RP, Freeman GR, Wojciak-Stothard B, Chester AH, El-Sherbiny IM, Mitchell JA, Yacoub MH.

J Cardiovasc Transl Res. 2016 Apr;9(2):162-4. doi: 10.1007/s12265-016-9684-2. Epub 2016 Mar 9.

13.

Nucleotide Catabolism on the Surface of Aortic Valve Xenografts; Effects of Different Decellularization Strategies.

Kutryb-Zajac B, Yuen AH, Khalpey Z, Zukowska P, Slominska EM, Taylor PM, Goldstein S, Heacox AE, Lavitrano M, Chester AH, Yacoub MH, Smolenski RT.

J Cardiovasc Transl Res. 2016 Apr;9(2):119-26. doi: 10.1007/s12265-016-9672-6. Epub 2016 Feb 1.

14.

Valve Endothelial Cells - Not Just Any Old Endothelial Cells.

Mongkoldhumrongkul N, Yacoub MH, Chester AH.

Curr Vasc Pharmacol. 2016;14(2):146-54. Review.

PMID:
26638797
15.

Mitral valve disease--morphology and mechanisms.

Levine RA, Hagége AA, Judge DP, Padala M, Dal-Bianco JP, Aikawa E, Beaudoin J, Bischoff J, Bouatia-Naji N, Bruneval P, Butcher JT, Carpentier A, Chaput M, Chester AH, Clusel C, Delling FN, Dietz HC, Dina C, Durst R, Fernandez-Friera L, Handschumacher MD, Jensen MO, Jeunemaitre XP, Le Marec H, Le Tourneau T, Markwald RR, Mérot J, Messas E, Milan DP, Neri T, Norris RA, Peal D, Perrocheau M, Probst V, Pucéat M, Rosenthal N, Solis J, Schott JJ, Schwammenthal E, Slaugenhaupt SA, Song JK, Yacoub MH; Leducq Mitral Transatlantic Network.

Nat Rev Cardiol. 2015 Dec;12(12):689-710. doi: 10.1038/nrcardio.2015.161. Epub 2015 Oct 20. Review.

16.

Modulation of human valve interstitial cell phenotype and function using a fibroblast growth factor 2 formulation.

Latif N, Quillon A, Sarathchandra P, McCormack A, Lozanoski A, Yacoub MH, Chester AH.

PLoS One. 2015 Jun 4;10(6):e0127844. doi: 10.1371/journal.pone.0127844. eCollection 2015.

17.

The role of endothelin-1 in pulmonary arterial hypertension.

Chester AH, Yacoub MH.

Glob Cardiol Sci Pract. 2014 Jun 18;2014(2):62-78. doi: 10.5339/gcsp.2014.29. eCollection 2014. Review.

18.

Shear stress and VEGF enhance endothelial differentiation of human adipose-derived stem cells.

Colazzo F, Alrashed F, Saratchandra P, Carubelli I, Chester AH, Yacoub MH, Taylor PM, Somers P.

Growth Factors. 2014 Oct;32(5):139-49. doi: 10.3109/08977194.2014.945642. Epub 2014 Aug 12.

PMID:
25112491
19.

The living aortic valve: From molecules to function.

Chester AH, El-Hamamsy I, Butcher JT, Latif N, Bertazzo S, Yacoub MH.

Glob Cardiol Sci Pract. 2014 Jan 29;2014(1):52-77. doi: 10.5339/gcsp.2014.11. eCollection 2014. Review.

20.

Immunohistochemical and functional analysis of ectonucleoside triphosphate diphosphohydrolase 1 (CD39) and ecto-5'-nucleotidase (CD73) in pig aortic valves.

Kaniewska E, Sielicka A, Sarathchandra P, Pelikant-Małecka I, Olkowicz M, Słomińska EM, Chester AH, Yacoub MH, Smoleński RT.

Nucleosides Nucleotides Nucleic Acids. 2014;33(4-6):305-12. doi: 10.1080/15257770.2014.885985.

PMID:
24940684
21.

Cardiovascular calcification violet pearl.

Bertazzo S, Steele JA, Chester AH, Yacoub MH, Stevens MM.

Lancet. 2014 Oct 4;384(9950):1294. doi: 10.1016/S0140-6736(13)62369-7. Epub 2014 May 23. No abstract available.

22.

Side-specific mechanical properties of valve endothelial cells.

Miragoli M, Yacoub MH, El-Hamamsy I, Sanchez-Alonso JL, Moshkov A, Mongkoldhumrongkul N, Padala M, Paramagurunathan S, Sarathchandra P, Korchev YE, Gorelik J, Chester AH.

Am J Physiol Heart Circ Physiol. 2014 Jul 1;307(1):H15-24.

23.

Expression of smooth muscle cell markers and co-activators in calcified aortic valves.

Latif N, Sarathchandra P, Chester AH, Yacoub MH.

Eur Heart J. 2015 Jun 1;36(21):1335-45. doi: 10.1093/eurheartj/eht547. Epub 2014 Jan 12.

PMID:
24419809
24.

The potential of anisotropic matrices as substrate for heart valve engineering.

Sohier J, Carubelli I, Sarathchandra P, Latif N, Chester AH, Yacoub MH.

Biomaterials. 2014 Feb;35(6):1833-44. doi: 10.1016/j.biomaterials.2013.10.061. Epub 2013 Dec 4.

PMID:
24314554
25.

Nano-analytical electron microscopy reveals fundamental insights into human cardiovascular tissue calcification.

Bertazzo S, Gentleman E, Cloyd KL, Chester AH, Yacoub MH, Stevens MM.

Nat Mater. 2013 Jun;12(6):576-83. doi: 10.1038/nmat3627. Epub 2013 Apr 21.

26.

Side-specific endothelial-dependent regulation of aortic valve calcification: interplay of hemodynamics and nitric oxide signaling.

Richards J, El-Hamamsy I, Chen S, Sarang Z, Sarathchandra P, Yacoub MH, Chester AH, Butcher JT.

Am J Pathol. 2013 May;182(5):1922-31. doi: 10.1016/j.ajpath.2013.01.037. Epub 2013 Mar 13.

27.

Bicuspid aortic valve and dilatation of the ascending aorta.

Misfeld M, Anyanwu AC, Chester AH.

Cardiol Res Pract. 2012;2012:142697. doi: 10.1155/2012/142697. Epub 2012 Nov 21. No abstract available.

28.

Characterization of porcine aortic valvular interstitial cell 'calcified' nodules.

Cloyd KL, El-Hamamsy I, Boonrungsiman S, Hedegaard M, Gentleman E, Sarathchandra P, Colazzo F, Gentleman MM, Yacoub MH, Chester AH, Stevens MM.

PLoS One. 2012;7(10):e48154. doi: 10.1371/journal.pone.0048154. Epub 2012 Oct 26.

29.

Time-dependent mechanical properties of aortic valve cusps: effect of glycosaminoglycan depletion.

Borghi A, New SE, Chester AH, Taylor PM, Yacoub MH.

Acta Biomater. 2013 Jan;9(1):4645-52. doi: 10.1016/j.actbio.2012.09.001. Epub 2012 Sep 7.

PMID:
22963848
30.

Atrioventricular valve development: new perspectives on an old theme.

de Vlaming A, Sauls K, Hajdu Z, Visconti RP, Mehesz AN, Levine RA, Slaugenhaupt SA, Hagège A, Chester AH, Markwald RR, Norris RA.

Differentiation. 2012 Jul;84(1):103-16. doi: 10.1016/j.diff.2012.04.001. Epub 2012 May 11. Review.

31.

Impact of γ-irradiation on extracellular matrix of porcine pulmonary valves.

Sarathchandra P, Smolenski RT, Yuen AH, Chester AH, Goldstein S, Heacox AE, Yacoub MH, Taylor PM.

J Surg Res. 2012 Aug;176(2):376-85. doi: 10.1016/j.jss.2011.10.011. Epub 2011 Nov 4.

PMID:
22172131
32.

Anisotropic strain transfer through the aortic valve and its relevance to the cellular mechanical environment.

Lewinsohn AD, Anssari-Benham A, Lee DA, Taylor PM, Chester AH, Yacoub MH, Screen HR.

Proc Inst Mech Eng H. 2011 Aug;225(8):821-30.

PMID:
21922958
33.

Cellular mechanisms in mitral valve disease.

Salhiyyah K, Yacoub MH, Chester AH.

J Cardiovasc Transl Res. 2011 Dec;4(6):702-9. doi: 10.1007/s12265-011-9318-7. Epub 2011 Sep 3. Review.

PMID:
21892743
34.

Elevated cyclic stretch and serotonin result in altered aortic valve remodeling via a mechanosensitive 5-HT(2A) receptor-dependent pathway.

Balachandran K, Hussain S, Yap CH, Padala M, Chester AH, Yoganathan AP.

Cardiovasc Pathol. 2012 May-Jun;21(3):206-13. doi: 10.1016/j.carpath.2011.07.005. Epub 2011 Aug 23.

PMID:
21865058
35.

Scanning ion conductance microscopy: a convergent high-resolution technology for multi-parametric analysis of living cardiovascular cells.

Miragoli M, Moshkov A, Novak P, Shevchuk A, Nikolaev VO, El-Hamamsy I, Potter CM, Wright P, Kadir SH, Lyon AR, Mitchell JA, Chester AH, Klenerman D, Lab MJ, Korchev YE, Harding SE, Gorelik J.

J R Soc Interface. 2011 Jul 6;8(60):913-25. doi: 10.1098/rsif.2010.0597. Epub 2011 Feb 16. Review.

36.

Induction of mesenchymal to endothelial transformation of adipose-derived stem cells.

Colazzo F, Chester AH, Taylor PM, Yacoub MH.

J Heart Valve Dis. 2010 Nov;19(6):736-44.

PMID:
21214098
37.

Extracellular matrix production by adipose-derived stem cells: implications for heart valve tissue engineering.

Colazzo F, Sarathchandra P, Smolenski RT, Chester AH, Tseng YT, Czernuszka JT, Yacoub MH, Taylor PM.

Biomaterials. 2011 Jan;32(1):119-27. doi: 10.1016/j.biomaterials.2010.09.003. Epub 2010 Nov 11.

PMID:
21074262
38.

The indirect alloimmune response causes microvascular endothelial dysfunction-a possible role for alloantibody.

Xu Y, Chester AH, Hariri B, McCormack A, Sarathchandra P, Rose ML.

Transplantation. 2010 Dec 15;90(11):1157-64. doi: 10.1097/TP.0b013e3181fa9480.

PMID:
21048535
39.

Expression of the familial cardiac valvular dystrophy gene, filamin-A, during heart morphogenesis.

Norris RA, Moreno-Rodriguez R, Wessels A, Merot J, Bruneval P, Chester AH, Yacoub MH, Hagège A, Slaugenhaupt SA, Aikawa E, Schott JJ, Lardeux A, Harris BS, Williams LK, Richards A, Levine RA, Markwald RR.

Dev Dyn. 2010 Jul;239(7):2118-27. doi: 10.1002/dvdy.22346.

40.

Interaction between bone morphogenetic proteins and endothelin-1 in human pulmonary artery smooth muscle.

Din S, Sarathchandra P, Yacoub MH, Chester AH.

Vascul Pharmacol. 2009 Nov-Dec;51(5-6):344-9. doi: 10.1016/j.vph.2009.09.001. Epub 2009 Sep 26.

PMID:
19786120
41.

Endothelium-dependent regulation of the mechanical properties of aortic valve cusps.

El-Hamamsy I, Balachandran K, Yacoub MH, Stevens LM, Sarathchandra P, Taylor PM, Yoganathan AP, Chester AH.

J Am Coll Cardiol. 2009 Apr 21;53(16):1448-55. doi: 10.1016/j.jacc.2008.11.056.

42.

Neuronal regulation of aortic valve cusps.

El-Hamamsy I, Yacoub MH, Chester AH.

Curr Vasc Pharmacol. 2009 Jan;7(1):40-6. Review.

PMID:
19149639
43.

Localisation and function of nerves in the aortic root.

Chester AH, Kershaw JD, Sarathchandra P, Yacoub MH.

J Mol Cell Cardiol. 2008 Jun;44(6):1045-52. doi: 10.1016/j.yjmcc.2008.03.014. Epub 2008 Mar 29.

PMID:
18485360
44.

A novel role of the sympatho-adrenergic system in regulating valve calcification.

Osman L, Chester AH, Sarathchandra P, Latif N, Meng W, Taylor PM, Yacoub MH.

Circulation. 2007 Sep 11;116(11 Suppl):I282-7.

PMID:
17846318
45.

Force generation of different human cardiac valve interstitial cells: relevance to individual valve function and tissue engineering.

Smith S, Taylor PM, Chester AH, Allen SP, Dreger SA, Eastwood M, Yacoub MH.

J Heart Valve Dis. 2007 Jul;16(4):440-6.

PMID:
17702371
46.

Antioxidant properties of the internal thoracic artery and the radial artery.

Mangoush O, Athanasiou T, Nakamura K, Johnson P, Smoienski R, Sarathchandra P, Oury T, Chester AH, Amrani M.

Heart Lung Circ. 2008 Feb;17(1):40-7. Epub 2007 Jul 2.

PMID:
17604222
47.

Molecular and functional characteristics of heart-valve interstitial cells.

Chester AH, Taylor PM.

Philos Trans R Soc Lond B Biol Sci. 2007 Aug 29;362(1484):1437-43.

48.

Magnetic resonance imaging of ferumoxide-labeled mesenchymal stem cells seeded on collagen scaffolds-relevance to tissue engineering.

Terrovitis JV, Bulte JW, Sarvananthan S, Crowe LA, Sarathchandra P, Batten P, Sachlos E, Chester AH, Czernuszka JT, Firmin DN, Taylor PM, Yacoub MH.

Tissue Eng. 2006 Oct;12(10):2765-75.

PMID:
17518646
49.

Characterization of structural and signaling molecules by human valve interstitial cells and comparison to human mesenchymal stem cells.

Latif N, Sarathchandra P, Thomas PS, Antoniw J, Batten P, Chester AH, Taylor PM, Yacoub MH.

J Heart Valve Dis. 2007 Jan;16(1):56-66.

PMID:
17315384
50.

Correlation between vascular responsivensss and expression of novel transcripts of the ETA-receptor in human vascular tissue.

Chester AH, Azam R, Felkin LE, George R, Brand N.

Vascul Pharmacol. 2007 Mar;46(3):181-7. Epub 2006 Oct 18.

PMID:
17126612

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