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Do genetic variations in proximal tubule transporters influence tenofovir-induced renal dysfunction? An exploratory study in a Ghanaian population.

Neary M, Olagunju A, Sarfo F, Phillips R, Moss D, Owen A, Chadwick D.

J Antimicrob Chemother. 2020 Feb 14. pii: dkaa008. doi: 10.1093/jac/dkaa008. [Epub ahead of print]


Author Correction: Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution.

Chan-Seng-Yue M, Kim JC, Wilson GW, Ng K, Figueroa EF, O'Kane GM, Connor AA, Denroche RE, Grant RC, McLeod J, Wilson JM, Jang GH, Zhang A, Liang SB, Borgida A, Chadwick D, Kalimuthu S, Lungu I, Bartlett JMS, Krzyzanowski PM, Sandhu V, Tiriac H, Froeling FEM, Karasinska JM, Topham JT, Renouf DJ, Schaeffer DF, Jones SJM, Marra MA, Laskin J, Chetty R, Stein LD, Zogopoulos G, Haibe-Kains B, Campbell PJ, Tuveson DA, Knox JJ, Fischer SE, Gallinger S, Notta F.

Nat Genet. 2020 Feb 12. doi: 10.1038/s41588-020-0588-3. [Epub ahead of print]


Meta-analysis of global livestock urine-derived nitrous oxide emissions from agricultural soils.

López-Aizpún M, Horrocks CA, Charteris AF, Marsden KA, Ciganda VS, Evans JR, Chadwick DR, Cárdenas LM.

Glob Chang Biol. 2020 Jan 23. doi: 10.1111/gcb.15012. [Epub ahead of print] Review.


Late HIV diagnosis and missed opportunities for testing: piloting a standardised, multi-source review process.

Horsley Downie J, Pegler M, Widdrington J, Price DA, Premchand N, Chadwick DR.

Int J STD AIDS. 2020 Jan 22:956462419868637. doi: 10.1177/0956462419868637. [Epub ahead of print] No abstract available.


A four-chemokine signature is associated with a T cell-inflamed phenotype in primary and metastatic pancreatic cancer.

Romero JM, Grünwald BT, Jang GH, Bavi PP, Jhaveri A, Masoomian M, Fischer SE, Zhang A, Denroche RE, Lungu IM, De Luca A, Bartlett JMS, Xu J, Li N, Dhaliwal S, Liang SB, Chadwick D, Vyas F, Bronsert P, Khokha R, McGaha TL, Notta F, Ohashi PS, Done SJ, O'Kane GM, Wilson JM, Knox JJ, Connor A, Wang Y, Zogopoulos G, Gallinger S.

Clin Cancer Res. 2020 Jan 21. pii: clincanres.2803.2019. doi: 10.1158/1078-0432.CCR-19-2803. [Epub ahead of print]


Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution.

Chan-Seng-Yue M, Kim JC, Wilson GW, Ng K, Figueroa EF, O'Kane GM, Connor AA, Denroche RE, Grant RC, McLeod J, Wilson JM, Jang GH, Zhang A, Dodd A, Liang SB, Borgida A, Chadwick D, Kalimuthu S, Lungu I, Bartlett JMS, Krzyzanowski PM, Sandhu V, Tiriac H, Froeling FEM, Karasinska JM, Topham JT, Renouf DJ, Schaeffer DF, Jones SJM, Marra MA, Laskin J, Chetty R, Stein LD, Zogopoulos G, Haibe-Kains B, Campbell PJ, Tuveson DA, Knox JJ, Fischer SE, Gallinger S, Notta F.

Nat Genet. 2020 Feb;52(2):231-240. doi: 10.1038/s41588-019-0566-9. Epub 2020 Jan 13. Erratum in: Nat Genet. 2020 Feb 12;:.


Determining virological suppression and resuppression by point-of-care viral load testing in a HIV care setting in sub-Saharan Africa.

Villa G, Abdullahi A, Owusu D, Smith C, Azumah M, Sayeed L, Austin H, Awuah D, Beloukas A, Chadwick D, Phillips R, Geretti AM.

EClinicalMedicine. 2020 Jan 5;18:100231. doi: 10.1016/j.eclinm.2019.12.001. eCollection 2020 Jan.


Microbial diversity dynamics during the self-acidification of dairy slurry.

Bastami MS, Jones DL, Chadwick DR.

Environ Technol. 2020 Jan 7:1-11. doi: 10.1080/09593330.2019.1706644. [Epub ahead of print]


Impact of water table levels and winter cover crops on greenhouse gas emissions from cultivated peat soils.

Wen Y, Zang H, Ma Q, Freeman B, Chadwick DR, Evans CD, Jones DL.

Sci Total Environ. 2019 Nov 20:135130. doi: 10.1016/j.scitotenv.2019.135130. [Epub ahead of print]


Reducing demand for computed tomography.

Chadwick DR.

Clin Med (Lond). 2019 Sep;19(5):429. doi: 10.7861/clinmedicine.19-5-429. No abstract available.


Data for life cycle assessment of legume biorefining for alcohol.

Lienhardt T, Black K, Saget S, Costa MP, Chadwick D, Rees R, Williams M, Spillane C, Iannetta P, Walker G, Styles D.

Data Brief. 2019 Aug 8;25:104242. doi: 10.1016/j.dib.2019.104242. eCollection 2019 Aug.


Nitrification represents the bottle-neck of sheep urine patch N2O emissions from extensively grazed organic soils.

Marsden KA, Holmberg JA, Jones DL, Charteris AF, Cárdenas LM, Chadwick DR.

Sci Total Environ. 2019 Dec 10;695:133786. doi: 10.1016/j.scitotenv.2019.133786. Epub 2019 Aug 6.


Developing a pan-cancer research autopsy programme.

Bavi P, Siva M, Abi-Saab T, Chadwick D, Dhani N, Butany J, Joshua AM, Roehrl MH.

J Clin Pathol. 2019 Oct;72(10):689-695. doi: 10.1136/jclinpath-2019-205874. Epub 2019 Jul 1.


Just the tonic! Legume biorefining for alcohol has the potential to reduce Europe's protein deficit and mitigate climate change.

Lienhardt T, Black K, Saget S, Costa MP, Chadwick D, Rees RM, Williams M, Spillane C, Iannetta PM, Walker G, Styles D.

Environ Int. 2019 Sep;130:104870. doi: 10.1016/j.envint.2019.05.064. Epub 2019 Jun 18.


Application of Bayesian statistics to estimate nitrous oxide emission factors of three nitrogen fertilisers on UK grasslands.

Cowan N, Levy P, Drewer J, Carswell A, Shaw R, Simmons I, Bache C, Marinheiro J, Brichet J, Sanchez-Rodriguez AR, Cotton J, Hill PW, Chadwick DR, Jones DL, Misselbrook TH, Skiba U.

Environ Int. 2019 Jul;128:362-370. doi: 10.1016/j.envint.2019.04.054. Epub 2019 May 8.


Treating late HIV diagnosis as a patient safety issue in the UK.

Chadwick DR, Freedman A.

Lancet HIV. 2019 Jun;6(6):e346-e348. doi: 10.1016/S2352-3018(19)30044-X. Epub 2019 May 3. No abstract available.


Psychological wellbeing and use of alcohol and recreational drugs: results of the British HIV Association (BHIVA) national audit 2017.

Parry S, Curtis H, Chadwick D; British HIV Association Audit and Standards Sub-Committee.

HIV Med. 2019 Jul;20(6):424-427. doi: 10.1111/hiv.12744. Epub 2019 Apr 22.


A critical review of the impacts of cover crops on nitrogen leaching, net greenhouse gas balance and crop productivity.

Abdalla M, Hastings A, Cheng K, Yue Q, Chadwick D, Espenberg M, Truu J, Rees RM, Smith P.

Glob Chang Biol. 2019 Aug;25(8):2530-2543. doi: 10.1111/gcb.14644. Epub 2019 May 13. Review.


Integration of Genomic and Transcriptional Features in Pancreatic Cancer Reveals Increased Cell Cycle Progression in Metastases.

Connor AA, Denroche RE, Jang GH, Lemire M, Zhang A, Chan-Seng-Yue M, Wilson G, Grant RC, Merico D, Lungu I, Bartlett JMS, Chadwick D, Liang SB, Eagles J, Mbabaali F, Miller JK, Krzyzanowski P, Armstrong H, Luo X, Jorgensen LGT, Romero JM, Bavi P, Fischer SE, Serra S, Hafezi-Bakhtiari S, Caglar D, Roehrl MHA, Cleary S, Hollingsworth MA, Petersen GM, Thayer S, Law CHL, Nanji S, Golan T, Smith AL, Borgida A, Dodd A, Hedley D, Wouters BG, O'Kane GM, Wilson JM, Zogopoulos G, Notta F, Knox JJ, Gallinger S.

Cancer Cell. 2019 Feb 11;35(2):267-282.e7. doi: 10.1016/j.ccell.2018.12.010. Epub 2019 Jan 24.


Nitrogen use efficiency and nitrous oxide emissions from five UK fertilised grasslands.

Cardenas LM, Bhogal A, Chadwick DR, McGeough K, Misselbrook T, Rees RM, Thorman RE, Watson CJ, Williams JR, Smith KA, Calvet S.

Sci Total Environ. 2019 Apr 15;661:696-710. doi: 10.1016/j.scitotenv.2019.01.082. Epub 2019 Jan 9.


Effects of four years of elevated ozone on microbial biomass and extracellular enzyme activities in a semi-natural grassland.

Wang J, Hayes F, Turner R, Chadwick DR, Mills G, Jones DL.

Sci Total Environ. 2019 Apr 10;660:260-268. doi: 10.1016/j.scitotenv.2019.01.040. Epub 2019 Jan 7.


Whole genomes define concordance of matched primary, xenograft, and organoid models of pancreas cancer.

Gendoo DMA, Denroche RE, Zhang A, Radulovich N, Jang GH, Lemire M, Fischer S, Chadwick D, Lungu IM, Ibrahimov E, Cao PJ, Stein LD, Wilson JM, Bartlett JMS, Tsao MS, Dhani N, Hedley D, Gallinger S, Haibe-Kains B.

PLoS Comput Biol. 2019 Jan 10;15(1):e1006596. doi: 10.1371/journal.pcbi.1006596. eCollection 2019 Jan.


Virological outcomes of boosted protease inhibitor-based first-line ART in subjects harbouring thymidine analogue-associated mutations as the sole form of transmitted drug resistance.

Geretti AM, White E, Orkin C, Tostevin A, Tilston P, Chadwick D, Leen C, Sabin C, Dunn DT; UK HIV Drug Resistance Database and UK CHIC Study.

J Antimicrob Chemother. 2019 Mar 1;74(3):746-753. doi: 10.1093/jac/dky468.


The environmental costs and benefits of high-yield farming.

Balmford A, Amano T, Bartlett H, Chadwick D, Collins A, Edwards D, Field R, Garnsworthy P, Green R, Smith P, Waters H, Whitmore A, Broom DM, Chara J, Finch T, Garnett E, Gathorne-Hardy A, Hernandez-Medrano J, Herrero M, Hua F, Latawiec A, Misselbrook T, Phalan B, Simmons BI, Takahashi T, Vause J, Zu Ermgassen E, Eisner R.

Nat Sustain. 2018 Sep 14;1(9):477-485.


Approaches to communication assessment with children and adults with profound intellectual and multiple disabilities.

Chadwick D, Buell S, Goldbart J.

J Appl Res Intellect Disabil. 2019 Mar;32(2):336-358. doi: 10.1111/jar.12530. Epub 2018 Nov 14.


Sensitive tumour detection and classification using plasma cell-free DNA methylomes.

Shen SY, Singhania R, Fehringer G, Chakravarthy A, Roehrl MHA, Chadwick D, Zuzarte PC, Borgida A, Wang TT, Li T, Kis O, Zhao Z, Spreafico A, Medina TDS, Wang Y, Roulois D, Ettayebi I, Chen Z, Chow S, Murphy T, Arruda A, O'Kane GM, Liu J, Mansour M, McPherson JD, O'Brien C, Leighl N, Bedard PL, Fleshner N, Liu G, Minden MD, Gallinger S, Goldenberg A, Pugh TJ, Hoffman MM, Bratman SV, Hung RJ, De Carvalho DD.

Nature. 2018 Nov;563(7732):579-583. doi: 10.1038/s41586-018-0703-0. Epub 2018 Nov 14.


In silico thrombin generation: Plasma composition imbalance and mortality in human immunodeficiency virus.

Brummel-Ziedins KE, Gissel M, Neuhaus J, Borges ÁH, Chadwick DR, Emery S, Neaton JD, Tracy RP, Baker JV; INSIGHT SMART, ESPRIT Study Groups.

Res Pract Thromb Haemost. 2018 Sep 11;2(4):708-717. doi: 10.1002/rth2.12147. eCollection 2018 Oct.


Investigating Humor in Social Interaction in People With Intellectual Disabilities: A Systematic Review of the Literature.

Chadwick DD, Platt T.

Front Psychol. 2018 Sep 21;9:1745. doi: 10.3389/fpsyg.2018.01745. eCollection 2018.


Effects of phosphogypsum, superphosphate, and dicyandiamide on gaseous emission and compost quality during sewage sludge composting.

Yuan J, Li Y, Chen S, Li D, Tang H, Chadwick D, Li S, Li W, Li G.

Bioresour Technol. 2018 Dec;270:368-376. doi: 10.1016/j.biortech.2018.09.023. Epub 2018 Sep 5.


Designing Vulnerable Zones of Nitrogen and Phosphorus Transfers To Control Water Pollution in China.

Bai Z, Lu J, Zhao H, Velthof GL, Oenema O, Chadwick D, Williams JR, Jin S, Liu H, Wang M, Strokal M, Kroeze C, Hu C, Ma L.

Environ Sci Technol. 2018 Aug 21;52(16):8987-8988. doi: 10.1021/acs.est.8b02651. Epub 2018 Jul 30. No abstract available.


Pyogenic brain abscess and subdural empyema: presentation, management, and factors predicting outcome.

Widdrington JD, Bond H, Schwab U, Price DA, Schmid ML, McCarron B, Chadwick DR, Narayanan M, Williams J, Ong E.

Infection. 2018 Dec;46(6):785-792. doi: 10.1007/s15010-018-1182-9. Epub 2018 Jul 27.


Drug resistance outcomes of long-term ART with tenofovir disoproxil fumarate in the absence of virological monitoring.

Villa G, Phillips RO, Smith C, Stockdale AJ, Ruggiero A, Beloukas A, Appiah LT, Chadwick D, Sarfo FS, Geretti AM.

J Antimicrob Chemother. 2018 Nov 1;73(11):3148-3157. doi: 10.1093/jac/dky281.


Evaluation of a vaccine passport to improve vaccine coverage in people living with HIV.

Chadwick DR, Corbett K, Mann S, Teruzzi B, Horner S.

Int J STD AIDS. 2018 Oct;29(12):1190-1193. doi: 10.1177/0956462418779472. Epub 2018 Jun 26.


Determining the influence of environmental and edaphic factors on the fate of the nitrification inhibitors DCD and DMPP in soil.

Guardia G, Marsden KA, Vallejo A, Jones DL, Chadwick DR.

Sci Total Environ. 2018 May 15;624:1202-1212. doi: 10.1016/j.scitotenv.2017.12.250. Epub 2017 Dec 27.


Life Cycle Assessment of Biofertilizer Production and Use Compared with Conventional Liquid Digestate Management.

Styles D, Adams P, Thelin G, Vaneeckhaute C, Chadwick D, Withers PJA.

Environ Sci Technol. 2018 Jul 3;52(13):7468-7476. doi: 10.1021/acs.est.8b01619. Epub 2018 Jun 12.


Effects of adding bulking agents on the biodrying of kitchen waste and the odor emissions produced.

Yuan J, Li Y, Zhang H, Zhang D, Chadwick D, Li G, Wang G, Chi M, Yang F.

J Environ Sci (China). 2018 May;67:344-355. doi: 10.1016/j.jes.2017.08.014. Epub 2017 Aug 30.


Renal health after long-term exposure to tenofovir disoproxil fumarate (TDF) in HIV/HBV positive adults in Ghana.

Villa G, Phillips RO, Smith C, Stockdale AJ, Beloukas A, Appiah LT, Chadwick D, Ruggiero A, Sarfo FS, Post F, Geretti AM.

J Infect. 2018 Jun;76(6):515-521. doi: 10.1016/j.jinf.2018.03.001. Epub 2018 Apr 24.


The contribution of cattle urine and dung to nitrous oxide emissions: Quantification of country specific emission factors and implications for national inventories.

Chadwick DR, Cardenas LM, Dhanoa MS, Donovan N, Misselbrook T, Williams JR, Thorman RE, McGeough KL, Watson CJ, Bell M, Anthony SG, Rees RM.

Sci Total Environ. 2018 Sep 1;635:607-617. doi: 10.1016/j.scitotenv.2018.04.152. Epub 2018 Apr 24.


Care, Compassion, Courage, Commitment, Communication and Competence: The 6 Cs.

Chadwick D.

J Perioper Pract. 2017 Oct;27(10):209-211. doi: 10.1177/175045891702701001.


Fosfomycin vs. quinolone-based antibiotic prophylaxis for transrectal ultrasound-guided biopsy of the prostate: a systematic review and meta-analysis.

Noreikaite J, Jones P, Fitzpatrick J, Amitharaj R, Pietropaolo A, Vasdev N, Chadwick D, Somani BK, Rai BP.

Prostate Cancer Prostatic Dis. 2018 Jun;21(2):153-160. doi: 10.1038/s41391-018-0032-2. Epub 2018 Feb 27. Review.


Critical review of the impacts of grazing intensity on soil organic carbon storage and other soil quality indicators in extensively managed grasslands.

Abdalla M, Hastings A, Chadwick DR, Jones DL, Evans CD, Jones MB, Rees RM, Smith P.

Agric Ecosyst Environ. 2018 Feb 1;253:62-81. doi: 10.1016/j.agee.2017.10.023. Review.


Hypocalcaemia and permanent hypoparathyroidism after total/bilateral thyroidectomy in the BAETS Registry.

Chadwick DR.

Gland Surg. 2017 Dec;6(Suppl 1):S69-S74. doi: 10.21037/gs.2017.09.14. Review.


Genomics-Driven Precision Medicine for Advanced Pancreatic Cancer: Early Results from the COMPASS Trial.

Aung KL, Fischer SE, Denroche RE, Jang GH, Dodd A, Creighton S, Southwood B, Liang SB, Chadwick D, Zhang A, O'Kane GM, Albaba H, Moura S, Grant RC, Miller JK, Mbabaali F, Pasternack D, Lungu IM, Bartlett JMS, Ghai S, Lemire M, Holter S, Connor AA, Moffitt RA, Yeh JJ, Timms L, Krzyzanowski PM, Dhani N, Hedley D, Notta F, Wilson JM, Moore MJ, Gallinger S, Knox JJ.

Clin Cancer Res. 2018 Mar 15;24(6):1344-1354. doi: 10.1158/1078-0432.CCR-17-2994. Epub 2017 Dec 29.


Prevalence of Dysphagia in People With Intellectual Disability: A Systematic Review.

Robertson J, Chadwick D, Baines S, Emerson E, Hatton C.

Intellect Dev Disabil. 2017 Dec;55(6):377-391. doi: 10.1352/1934-9556-55.6.377. Review.


Global analysis of agricultural soil denitrification in response to fertilizer nitrogen.

Wang J, Chadwick DR, Cheng Y, Yan X.

Sci Total Environ. 2018 Mar;616-617:908-917. doi: 10.1016/j.scitotenv.2017.10.229. Epub 2017 Oct 28.


Hepatitis C Virus (HCV) RNA screening and sequencing using dry plasma spots.

Geretti AM, King S, Adjei-Asante K, Appiah LT, Owusu DO, Sarfo FS, Chadwick D, Phillips RO, Beloukas A.

J Clin Virol. 2017 Dec;97:18-21. doi: 10.1016/j.jcv.2017.10.012. Epub 2017 Oct 23.


Factors affecting access to daily oral and dental care among adults with intellectual disabilities.

Chadwick D, Chapman M, Davies G.

J Appl Res Intellect Disabil. 2018 May;31(3):379-394. doi: 10.1111/jar.12415. Epub 2017 Oct 17.


Enhanced-efficiency fertilizers are not a panacea for resolving the nitrogen problem.

Li T, Zhang W, Yin J, Chadwick D, Norse D, Lu Y, Liu X, Chen X, Zhang F, Powlson D, Dou Z.

Glob Chang Biol. 2018 Feb;24(2):e511-e521. doi: 10.1111/gcb.13918. Epub 2017 Nov 2.


Hepatitis B, hepatitis C, and mortality among HIV-positive individuals.

Thornton AC, Jose S, Bhagani S, Chadwick D, Dunn D, Gilson R, Main J, Nelson M, Rodger A, Taylor C, Youssef E, Leen C, Gompels M, Kegg S, Schwenk A, Sabin C; UK Collaborative HIV cohort (UK CHIC) steering committee.

AIDS. 2017 Nov 28;31(18):2525-2532. doi: 10.1097/QAD.0000000000001646.

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