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Items: 1 to 50 of 127

1.

Hemin interactions and alterations of the subcellular localization of prion protein.

Lee KS, Raymond LD, Schoen B, Raymond GJ, Kett L, Moore RA, Johnson LM, Taubner L, Speare JO, Onwubiko HA, Baron GS, Caughey WS, Caughey B.

J Biol Chem. 2007 Dec 14;282(50):36525-33. Epub 2007 Oct 9.

2.

Cyclic tetrapyrrole sulfonation, metals, and oligomerization in antiprion activity.

Caughey WS, Priola SA, Kocisko DA, Raymond LD, Ward A, Caughey B.

Antimicrob Agents Chemother. 2007 Nov;51(11):3887-94. Epub 2007 Aug 20.

3.

Prions and transmissible spongiform encephalopathy (TSE) chemotherapeutics: A common mechanism for anti-TSE compounds?

Caughey B, Caughey WS, Kocisko DA, Lee KS, Silveira JR, Morrey JD.

Acc Chem Res. 2006 Sep;39(9):646-53. Review.

PMID:
16981681
4.

A porphyrin increases survival time of mice after intracerebral prion infection.

Kocisko DA, Caughey WS, Race RE, Roper G, Caughey B, Morrey JD.

Antimicrob Agents Chemother. 2006 Feb;50(2):759-61.

5.

Inhibition of protease-resistant prion protein formation in a transformed deer cell line infected with chronic wasting disease.

Raymond GJ, Olsen EA, Lee KS, Raymond LD, Bryant PK 3rd, Baron GS, Caughey WS, Kocisko DA, McHolland LE, Favara C, Langeveld JP, van Zijderveld FG, Mayer RT, Miller MW, Williams ES, Caughey B.

J Virol. 2006 Jan;80(2):596-604.

6.

Anesthetic-like interactions of nitric oxide with albumin and hemeproteins. A mechanism for control of protein function.

Sampath V, Zhao XJ, Caughey WS.

J Biol Chem. 2001 Apr 27;276(17):13635-43. Epub 2001 Jan 26.

7.

Porphyrin and phthalocyanine antiscrapie compounds.

Priola SA, Raines A, Caughey WS.

Science. 2000 Feb 25;287(5457):1503-6.

8.

Novel therapeutic uses for porphyrins and phthalocyanines in the transmissible spongiform encephalopathies.

Priola SA, Caughey B, Caughey WS.

Curr Opin Microbiol. 1999 Oct;2(5):563-6. Review. No abstract available.

PMID:
10617376
9.

Potential roles of myoglobin autoxidation in myocardial ischemia-reperfusion injury.

Gunther MR, Sampath V, Caughey WS.

Free Radic Biol Med. 1999 Jun;26(11-12):1388-95.

PMID:
10401602
10.

Inhibition of protease-resistant prion protein formation by porphyrins and phthalocyanines.

Caughey WS, Raymond LD, Horiuchi M, Caughey B.

Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12117-22.

11.
12.

Cytochrome c oxidase catalysis of the reduction of nitric oxide to nitrous oxide.

Zhao XJ, Sampath V, Caughey WS.

Biochem Biophys Res Commun. 1995 Jul 26;212(3):1054-60.

PMID:
7626092
13.
15.
17.

Infrared analysis of ligand- and oxidation-induced conformational changes in hemoglobins and myoglobins.

Dong A, Huang P, Caughey B, Caughey WS.

Arch Biochem Biophys. 1995 Feb 1;316(2):893-8.

PMID:
7864648
18.

Fourier transform infrared analysis of carbonyl and nitrosyl complexes of cytochrome-c oxidase from Saccharomyces cerevisiae.

Zhao XJ, Caughey WS, Poyton RO.

Methods Enzymol. 1995;260:399-406. No abstract available.

PMID:
8592462
19.

Infrared characterization of nitric oxide bonding to bovine heart cytochrome c oxidase and myoglobin.

Zhao XJ, Sampath V, Caughey WS.

Biochem Biophys Res Commun. 1994 Oct 28;204(2):537-43.

PMID:
7980511
20.
21.

Characterization of sites occupied by the anesthetic nitrous oxide within proteins by infrared spectroscopy.

Dong A, Huang P, Zhao XJ, Sampath V, Caughey WS.

J Biol Chem. 1994 Sep 30;269(39):23911-7.

22.

Magainin oligomers reversibly dissipate delta microH+ in cytochrome oxidase liposomes.

Juretić D, Hendler RW, Kamp F, Caughey WS, Zasloff M, Westerhoff HV.

Biochemistry. 1994 Apr 19;33(15):4562-70.

PMID:
8161511
23.
25.

Characterization of interactions of nitric oxide with human hemoglobin A by infrared spectroscopy.

Sampath V, Zhao XJ, Caughey WS.

Biochem Biophys Res Commun. 1994 Jan 14;198(1):281-7.

PMID:
8292032
26.

Infrared methods for study of hemoglobin reactions and structures.

Dong A, Caughey WS.

Methods Enzymol. 1994;232:139-75. Review. No abstract available.

PMID:
8057858
27.

Probing heart cytochrome c oxidase structure and function by infrared spectroscopy.

Caughey WS, Dong A, Sampath V, Yoshikawa S, Zhao XJ.

J Bioenerg Biomembr. 1993 Apr;25(2):81-91. Review.

PMID:
8389753
28.

Destabilizing effects of replacing a surface lysine of cytochrome c with aromatic amino acids: implications for the denatured state.

Bowler BE, May K, Zaragoza T, York P, Dong A, Caughey WS.

Biochemistry. 1993 Jan 12;32(1):183-90.

PMID:
8380333
29.
30.

Spectroscopic studies of an insect hemoglobin from the backswimmer Buenoa margaritacea (Hemiptera:Notonectidae).

Osmulski PA, Vossbrinck CR, Sampath V, Caughey WS, Debrunner PG.

Biochem Biophys Res Commun. 1992 Sep 16;187(2):570-6.

PMID:
1326950
31.
33.

Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy.

Caughey BW, Dong A, Bhat KS, Ernst D, Hayes SF, Caughey WS.

Biochemistry. 1991 Aug 6;30(31):7672-80. Erratum in: Biochemistry 1991 Oct 29;30(43):10600.

PMID:
1678278
34.

Salicylhydroxamic acid inhibits myeloperoxidase activity.

Ikeda-Saito M, Shelley DA, Lu L, Booth KS, Caughey WS, Kimura S.

J Biol Chem. 1991 Feb 25;266(6):3611-6.

35.

Interaction of halides with the cyanide complex of myeloperoxidase: a model for substrate binding to compound I.

Lee HC, Booth KS, Caughey WS, Ikeda-Saito M.

Biochim Biophys Acta. 1991 Jan 29;1076(2):317-20.

PMID:
1847831
36.

Pathobiochemistry of CO poisoning.

Young LJ, Caughey WS.

FEBS Lett. 1990 Oct 15;272(1-2):1-6. Review.

37.

Infrared spectra of carbonyl hemoglobins: characterization of dynamic heme pocket conformers.

Potter WT, Hazzard JH, Choc MG, Tucker MP, Caughey WS.

Biochemistry. 1990 Jul 3;29(26):6283-95.

PMID:
2207074
39.

A nuclear Overhauser effect study of the active site of myeloperoxidase. Structural similarity of the prosthetic group to that on lactoperoxidase.

Dugad LB, La Mar GN, Lee HC, Ikeda-Saito M, Booth KS, Caughey WS.

J Biol Chem. 1990 May 5;265(13):7173-9.

40.

Protein secondary structures in water from second-derivative amide I infrared spectra.

Dong A, Huang P, Caughey WS.

Biochemistry. 1990 Apr 3;29(13):3303-8.

PMID:
2159334
41.

Bovine myeloperoxidase and lactoperoxidase each contain a high affinity site for calcium.

Booth KS, Kimura S, Lee HC, Ikeda-Saito M, Caughey WS.

Biochem Biophys Res Commun. 1989 Apr 28;160(2):897-902.

PMID:
2541717
42.
43.

Demonstration that spleen green hemeprotein is identical to granulocyte myeloperoxidase.

Ikeda-Saito M, Lee HC, Adachi K, Eck HS, Prince RC, Booth KS, Caughey WS, Kimura S.

J Biol Chem. 1989 Mar 15;264(8):4559-63.

44.

Distal His----Arg mutation in bovine myoglobin results in a ligand binding site similar to the abnormal beta site of hemoglobin Zurich (beta 63 His----Arg).

Shimada H, Dong A, Matsushima-Hibiya Y, Ishimura Y, Caughey WS.

Biochem Biophys Res Commun. 1989 Jan 16;158(1):110-4.

PMID:
2912443
45.

Parasite proteases and antimalarial activities of protease inhibitors.

Vander Jagt DL, Caughey WS, Campos NM, Hunsaker LA, Zanner MA.

Prog Clin Biol Res. 1989;313:105-18. No abstract available.

PMID:
2675111
46.

Infrared spectroscopy of a single cell--the human erythrocyte.

Dong A, Messerschmidt RG, Reffner JA, Caughey WS.

Biochem Biophys Res Commun. 1988 Oct 31;156(2):752-6.

PMID:
3190679
47.

The site and mechanism of dioxygen reduction in bovine heart cytochrome c oxidase.

Einarsdóttir O, Choc MG, Weldon S, Caughey WS.

J Biol Chem. 1988 Sep 25;263(27):13641-54.

49.

Crystalline cytochrome c oxidase of bovine heart mitochondrial membrane: composition and x-ray diffraction studies.

Yoshikawa S, Tera T, Takahashi Y, Tsukihara T, Caughey WS.

Proc Natl Acad Sci U S A. 1988 Mar;85(5):1354-8.

50.

Metals of bovine heart cytochrome c oxidase.

Yewey GL, Caughey WS.

Ann N Y Acad Sci. 1988;550:22-32. No abstract available.

PMID:
2854394

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