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Items: 1 to 50 of 72

1.

Mitochondrial DNA somatic mutation burden and heteroplasmy are associated with chronological age, smoking, and HIV infection.

Ziada AS, Lu MY, Ignas-Menzies J, Paintsil E, Li M, Ogbuagu O, Saberi S, Hsieh AYY, Sattha B, Harrigan PR, Kalloger S, Côté HCF; CIHR team grant on cellular aging, HIV comorbidities in women, children (CARMA).

Aging Cell. 2019 Aug 13:e13018. doi: 10.1111/acel.13018. [Epub ahead of print]

2.

Dynamics of leukocyte telomere length in pregnant women living with HIV, and HIV-negative pregnant women: A longitudinal observational study.

Saberi S, Kalloger SE, Zhu MMT, Sattha B, Maan EJ, van Schalkwyk J, Money DM, Côté HCF; CIHR Team in Cellular Aging and HIV Comorbidities in Women and Children (CARMA).

PLoS One. 2019 Mar 6;14(3):e0212273. doi: 10.1371/journal.pone.0212273. eCollection 2019.

3.

Exploring the live birth rates of women living with HIV in British Columbia, Canada.

Van Ommen CE, Albert AYK, Piske M, Money DM, Cote HCF, Lima VD, Maan EJ, Alimenti A, van Schalkwyk J, Pick N, Murray MCM.

PLoS One. 2019 Feb 6;14(2):e0211434. doi: 10.1371/journal.pone.0211434. eCollection 2019.

4.

Rivaroxaban and apixaban induce clotting factor Xa fibrinolytic activity.

Carter RLR, Talbot K, Hur WS, Meixner SC, Van Der Gugten JG, Holmes DT, Côté HCF, Kastrup CJ, Smith TW, Lee AYY, Pryzdial ELG.

J Thromb Haemost. 2018 Nov;16(11):2276-2288. doi: 10.1111/jth.14281. Epub 2018 Oct 9.

PMID:
30176116
5.

Neurodevelopmental outcomes and in-utero antiretroviral exposure in HIV-exposed uninfected children.

Piske M, Budd MA, Qiu AQ, Maan EJ, Sauvé LJ, Forbes JC, Alimenti A, Janssen P, Côté HCF; CIHR Team Grant on Cellular Aging and HIV Comorbidities in Women and Children (CARMA).

AIDS. 2018 Nov 13;32(17):2583-2592. doi: 10.1097/QAD.0000000000001985.

PMID:
30134292
6.

A mitochondrial DNA D loop insertion detected almost exclusively in non-replicating tissues with maternal inheritance across three generations.

Sharma MA, Lee JYJ, Tam A, Sattha B, Mackenzie IR, Vallance HD, Sirrs S, Hannah-Shmouni F, Côté HCF, Mattman A.

Mitochondrion. 2019 May;46:298-301. doi: 10.1016/j.mito.2018.08.002. Epub 2018 Aug 13.

PMID:
30114489
7.

Health Care Provider Utilization and Cost of an mHealth Intervention in Vulnerable People Living With HIV in Vancouver, Canada: Prospective Study.

Campbell AR, Kinvig K, Côté HC, Lester RT, Qiu AQ, Maan EJ, Alimenti A, Pick N, Murray MC.

JMIR Mhealth Uhealth. 2018 Jul 9;6(7):e152. doi: 10.2196/mhealth.9493.

8.

A Monochrome Multiplex Real-Time Quantitative PCR Assay for the Measurement of Mitochondrial DNA Content.

Hsieh AYY, Budd M, Deng D, Gadawska I, Côté HCF.

J Mol Diagn. 2018 Sep;20(5):612-620. doi: 10.1016/j.jmoldx.2018.05.001. Epub 2018 Jun 22.

PMID:
29936256
9.

Leukocyte Telomere Length in HIV Infection: A Marker of Persistent Immune Aging or Transient Immune Reconstitution?

Côté HCF, Hsieh AYY.

J Infect Dis. 2018 Oct 5;218(10):1521-1522. doi: 10.1093/infdis/jiy365. No abstract available.

PMID:
29912474
10.

Surviving and Thriving-Shifting the Public Health Response to HIV-Exposed Uninfected Children: Report of the 3rd HIV-Exposed Uninfected Child Workshop.

Slogrove AL, Becquet R, Chadwick EG, Côté HCF, Essajee S, Hazra R, Leroy V, Mahy M, Murenga M, Wambui Mwangi J, Oyiengo L, Rollins N, Penazzato M, Seage GR 3rd, Serghides L, Vicari M, Powis KM.

Front Pediatr. 2018 May 30;6:157. doi: 10.3389/fped.2018.00157. eCollection 2018.

11.

Premature Spinal Bone Loss in Women Living with HIV is Associated with Shorter Leukocyte Telomere Length.

Kalyan S, Pick N, Mai A, Murray MCM, Kidson K, Chu J, Albert AYK, Côté HCF, Maan EJ, Goshtasebi A, Money DM, Prior JC.

Int J Environ Res Public Health. 2018 May 18;15(5). pii: E1018. doi: 10.3390/ijerph15051018.

12.

Elevated Cell-Free Mitochondrial DNA in Filtered Plasma Is Associated With HIV Infection and Inflammation.

Arshad O, Gadawska I, Sattha B, Côté HCF, Hsieh AYY; Canadian Institutes of Health Research Team on Cellular Aging and HIV Comorbidities in Women and Children (CARMA).

J Acquir Immune Defic Syndr. 2018 May 1;78(1):111-118. doi: 10.1097/QAI.0000000000001650.

PMID:
29630031
13.

Blood Mitochondrial DNA Content in HIV-Exposed Uninfected Children with Autism Spectrum Disorder.

Budd MA, Calli K, Samson L, Bowes J, Hsieh AYY, Forbes JC, Bitnun A, Singer J, Kakkar F, Alimenti A, Maan EJ, Lewis MES, Gentile C, Côté HCF, Brophy JC.

Viruses. 2018 Feb 11;10(2). pii: E77. doi: 10.3390/v10020077.

14.

Leukocyte Telomere Length at Birth and During the Early Life of Children Exposed to but Uninfected With HIV After In Utero Exposure to Antiretrovirals.

Ajaykumar A, Soudeyns H, Kakkar F, Brophy J, Bitnun A, Alimenti A, Albert AYK, Money DM, Côté HCF; CIHR Team in Cellular Aging and HIV Comorbidities in Women and Children; CIHR Team in Cellular Aging and HIV Comorbidities in Women and Children.

J Infect Dis. 2018 Feb 14;217(5):710-720. doi: 10.1093/infdis/jix618.

15.

Lower mitochondrial DNA and altered mitochondrial fuel metabolism in HIV-exposed uninfected infants in Cameroon.

Jao J, Powis KM, Kirmse B, Yu C, Epie F, Nshom E, Abrams EJ, Sperling RS, Leroith D, Geffner ME, Kurland IJ, Côté HCF.

AIDS. 2017 Nov 28;31(18):2475-2481. doi: 10.1097/QAD.0000000000001647.

16.

Rapid Decrease in Peripheral Blood Mononucleated Cell Telomere Length After HIV Seroconversion, but Not HCV Seroconversion.

Gonzalez-Serna A, Ajaykumar A, Gadawski I, Muñoz-Fernández MA, Hayashi K, Harrigan PR, Côté HCF.

J Acquir Immune Defic Syndr. 2017 Sep 1;76(1):e29-e32. doi: 10.1097/QAI.0000000000001446. No abstract available.

17.

Competing Factors Link to Bone Health in Polycystic Ovary Syndrome: Chronic Low-Grade Inflammation Takes a Toll.

Kalyan S, Patel MS, Kingwell E, Côté HCF, Liu D, Prior JC.

Sci Rep. 2017 Jun 13;7(1):3432. doi: 10.1038/s41598-017-03685-x.

18.
19.

Optimization of a Relative Telomere Length Assay by Monochromatic Multiplex Real-Time Quantitative PCR on the LightCycler 480: Sources of Variability and Quality Control Considerations.

Hsieh AYY, Saberi S, Ajaykumar A, Hukezalie K, Gadawski I, Sattha B, Côté HCF.

J Mol Diagn. 2016 May;18(3):425-437. doi: 10.1016/j.jmoldx.2016.01.004. Epub 2016 Mar 8.

20.

Endocrine abnormalities in HIV-infected women are associated with peak viral load - the Children and Women: AntiRetrovirals and Markers of Aging (CARMA) Cohort.

Sokalski KM, Chu J, Mai AY, Qiu AQ, Albert AY, Zanet DL, Côté HC, Maan EJ, Pick N, Prior JC, Money DM, Murray MC; CIHR team grant on HIV therapy and aging: CARMA.

Clin Endocrinol (Oxf). 2016 Mar;84(3):452-62. doi: 10.1111/cen.12881. Epub 2015 Oct 20.

PMID:
26300027
21.

Evidence of Subclinical mtDNA Alterations in HIV-Infected Pregnant Women Receiving Combination Antiretroviral Therapy Compared to HIV-Negative Pregnant Women.

Money DM, Wagner EC, Maan EJ, Chaworth-Musters T, Gadawski I, van Schalkwyk JE, Forbes JC, Burdge DR, Albert AY, Lohn Z, Côté HC; Oak Tree Clinic Research Group.

PLoS One. 2015 Aug 6;10(8):e0135041. doi: 10.1371/journal.pone.0135041. eCollection 2015.

22.

Childhood Conscientiousness and Leukocyte Telomere Length 40 Years Later in Adult Women--Preliminary Findings of a Prospective Association.

Edmonds GW, Côté HC, Hampson SE.

PLoS One. 2015 Jul 28;10(7):e0134077. doi: 10.1371/journal.pone.0134077. eCollection 2015.

23.

Survival of effector CD8+ T cells during influenza infection is dependent on autophagy.

Schlie K, Westerback A, DeVorkin L, Hughson LR, Brandon JM, MacPherson S, Gadawski I, Townsend KN, Poon VI, Elrick MA, Côté HC, Abraham N, Wherry EJ, Mizushima N, Lum JJ.

J Immunol. 2015 May 1;194(9):4277-86. doi: 10.4049/jimmunol.1402571. Epub 2015 Apr 1.

24.

Impaired NLRP3 inflammasome activity during fetal development regulates IL-1β production in human monocytes.

Sharma AA, Jen R, Kan B, Sharma A, Marchant E, Tang A, Gadawski I, Senger C, Skoll A, Turvey SE, Sly LM, Côté HC, Lavoie PM.

Eur J Immunol. 2015 Jan;45(1):238-49. doi: 10.1002/eji.201444707. Epub 2014 Nov 17.

25.

Soluble CD163 is associated with shortened telomere length in HIV-infected patients.

Srinivasa S, Fitch KV, Petrow E, Burdo TH, Williams KC, Lo J, Cȏté HCF, Grinspoon SK.

J Acquir Immune Defic Syndr. 2014 Dec 1;67(4):414-418. doi: 10.1097/QAI.0000000000000329.

26.

Cognitive and language outcomes in HIV-uninfected infants exposed to combined antiretroviral therapy in utero and through extended breast-feeding.

Ngoma MS, Hunter JA, Harper JA, Church PT, Mumba S, Chandwe M, Côté HC, Albert AY, Smith ML, Selemani C, Sandstrom PA, Bandenduck L, Ndlovu U, Khan S, Roa L, Silverman MS.

AIDS. 2014 Jul;28 Suppl 3:S323-30. doi: 10.1097/QAD.0000000000000357.

PMID:
24991905
27.

Select neurocognitive impairment in HIV-infected women: associations with HIV viral load, hepatitis C virus, and depression, but not leukocyte telomere length.

Giesbrecht CJ, Thornton AE, Hall-Patch C, Maan EJ, Côté HC, Money DM, Murray M, Pick N.

PLoS One. 2014 Mar 4;9(3):e89556. doi: 10.1371/journal.pone.0089556. eCollection 2014.

28.

Association between short leukocyte telomere length and HIV infection in a cohort study: No evidence of a relationship with antiretroviral therapy.

Zanet DL, Thorne A, Singer J, Maan EJ, Sattha B, Le Campion A, Soudeyns H, Pick N, Murray M, Money DM, Côté HC; CIHR Emerging Team Grant on HIV Therapy and Aging: CARMA.

Clin Infect Dis. 2014 May;58(9):1322-32. doi: 10.1093/cid/ciu051. Epub 2014 Jan 22.

PMID:
24457340
29.

Nitrogen-bisphosphonate therapy is linked to compromised coenzyme Q10 and vitamin E status in postmenopausal women.

Kalyan S, Huebbe P, Esatbeyoglu T, Niklowitz P, Côté HC, Rimbach G, Kabelitz D.

J Clin Endocrinol Metab. 2014 Apr;99(4):1307-13. doi: 10.1210/jc.2013-3648. Epub 2014 Jan 13.

PMID:
24423355
30.

Blood and dried blood spot telomere length measurement by qPCR: assay considerations.

Zanet DL, Saberi S, Oliveira L, Sattha B, Gadawski I, Côté HC.

PLoS One. 2013;8(2):e57787. doi: 10.1371/journal.pone.0057787. Epub 2013 Feb 25.

31.

Decreased skeletal muscle mitochondrial DNA in patients with statin-induced myopathy.

Stringer HA, Sohi GK, Maguire JA, Côté HC.

J Neurol Sci. 2013 Feb 15;325(1-2):142-7. doi: 10.1016/j.jns.2012.12.023. Epub 2013 Jan 11.

PMID:
23312852
32.

In vitro and ex vivo inhibition of human telomerase by anti-HIV nucleoside reverse transcriptase inhibitors (NRTIs) but not by non-NRTIs.

Hukezalie KR, Thumati NR, Côté HC, Wong JM.

PLoS One. 2012;7(11):e47505. doi: 10.1371/journal.pone.0047505. Epub 2012 Nov 15.

33.

Quantification of mitochondrial toxicity in HIV-infected individuals by quantitative PCR compared to flow cytometry.

Wagner TA, Lin CH, Tobin NH, Côté HC, Sloan DD, Jerome KR, Frenkel LM.

Cytometry B Clin Cytom. 2013 Jan-Feb;84(1):55-8. doi: 10.1002/cyto.b.21045. Epub 2012 Oct 8.

34.

Leukocyte telomere length in HIV-infected and HIV-exposed uninfected children: shorter telomeres with uncontrolled HIV viremia.

Côté HC, Soudeyns H, Thorne A, Alimenti A, Lamarre V, Maan EJ, Sattha B, Singer J, Lapointe N, Money DM, Forbes J; CIHR Emerging Team in HIV therapy, aging (CARMA), Wong J, Bitnun A, Samson L, Brophy J, Burdge D, Pick N, van Schalkwyk J, Montaner J, Harris M, Janssen P.

PLoS One. 2012;7(7):e39266. doi: 10.1371/journal.pone.0039266. Epub 2012 Jul 16.

35.

Leukocyte telomere length in HIV-infected pregnant women treated with antiretroviral drugs during pregnancy and their uninfected infants.

Imam T, Jitratkosol MH, Soudeyns H, Sattha B, Gadawski I, Maan E, Forbes JC, Alimenti A, Lapointe N, Lamarre V, Money DM, Côté HC; CIHR Emerging Team Grant on HIV Therapy and Aging: CARMA.

J Acquir Immune Defic Syndr. 2012 Aug 15;60(5):495-502.

PMID:
22580562
36.

Blood mitochondrial DNA mutations in HIV-infected women and their infants exposed to HAART during pregnancy.

Jitratkosol MH, Sattha B, Maan EJ, Gadawski I, Harrigan PR, Forbes JC, Alimenti A, van Schalkwyk J, Money DM, Côté HC; CIHR Emerging Team Grant on HIV Therapy and Aging (CARMA).

AIDS. 2012 Mar 27;26(6):675-83. doi: 10.1097/QAD.0b013e32835142eb.

PMID:
22436539
37.

Inhibition of glutamine-dependent autophagy increases t-PA production in CHO cell fed-batch processes.

Jardon MA, Sattha B, Braasch K, Leung AO, Côté HC, Butler M, Gorski SM, Piret JM.

Biotechnol Bioeng. 2012 May;109(5):1228-38. doi: 10.1002/bit.24393. Epub 2011 Dec 21.

PMID:
22125188
38.

Quality assessment of human mitochondrial DNA quantification: MITONAUTS, an international multicentre survey.

Côté HC, Gerschenson M, Walker UA, Miro O, Garrabou G, Hammond E, Villarroya J, Giralt M, Villarroya F, Cinque P, Garcia-Arumi E, Andreu AL, Pinti M, Cossarizza A.

Mitochondrion. 2011 May;11(3):520-7. doi: 10.1016/j.mito.2011.01.011. Epub 2011 Feb 22.

39.

Ophthalmoplegia and ptosis: mitochondrial toxicity in patients receiving HIV therapy.

Pfeffer G, Côté HC, Montaner JS, Li CC, Jitratkosol M, Mezei MM.

Neurology. 2009 Jul 7;73(1):71-2. doi: 10.1212/WNL.0b013e3181aae814. No abstract available.

40.

Perinatal exposure to antiretroviral therapy is associated with increased blood mitochondrial DNA levels and decreased mitochondrial gene expression in infants.

Côté HC, Raboud J, Bitnun A, Alimenti A, Money DM, Maan E, Costei A, Gadawski I, Diong C, Read S, Shen S, Harrigan PR, Burdge DR, King SM, Forbes JC.

J Infect Dis. 2008 Sep 15;198(6):851-9. doi: 10.1086/591253.

PMID:
18684095
41.

Liver ultrastructural morphology and mitochondrial DNA levels in HIV/hepatitis C virus coinfection: no evidence of mitochondrial damage with highly active antiretroviral therapy.

Matsukura M, Chu FF, Au M, Lu H, Chen J, Rietkerk S, Barrios R, Farley JD, Montaner JS, Montessori VC, Walker DC, Côté HC.

AIDS. 2008 Jun 19;22(10):1226-9. doi: 10.1097/QAD.0b013e328303be16.

PMID:
18525271
42.

Changes in metabolic toxicity after switching from stavudine/didanosine to tenofovir/lamivudine--a Staccato trial substudy.

Ananworanich J, Nuesch R, Côté HC, Kerr SJ, Hill A, Jupimai T, Laopraynak N, Saenawat S, Ruxrungtham K, Hirschel B.

J Antimicrob Chemother. 2008 Jun;61(6):1340-3. doi: 10.1093/jac/dkn097. Epub 2008 Mar 12.

PMID:
18339636
43.

Longitudinal effects of thymidine analogues on mtDNA, mtRNA and multidrug resistance (MDR-1) induction in cultured cells.

Papp E, Gadawski I, Côté HC.

J Antimicrob Chemother. 2008 May;61(5):1048-52. doi: 10.1093/jac/dkn067. Epub 2008 Feb 28.

PMID:
18310046
45.

Mechanisms of antiretroviral therapy-induced mitochondrial dysfunction.

Côté HC.

Curr Opin HIV AIDS. 2007 Jul;2(4):253-60. doi: 10.1097/COH.0b013e3281df3410.

PMID:
19372896
46.

Decreased skeletal muscle mitochondrial DNA in patients treated with high-dose simvastatin.

Schick BA, Laaksonen R, Frohlich JJ, Päivä H, Lehtimäki T, Humphries KH, Côté HC.

Clin Pharmacol Ther. 2007 May;81(5):650-3. Epub 2007 Feb 28.

PMID:
17329991
47.

Effects of a nucleoside reverse transcriptase inhibitor, stavudine, on glucose disposal and mitochondrial function in muscle of healthy adults.

Fleischman A, Johnsen S, Systrom DM, Hrovat M, Farrar CT, Frontera W, Fitch K, Thomas BJ, Torriani M, Côté HC, Grinspoon SK.

Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1666-73. Epub 2007 Feb 6.

48.

HIV therapy, hepatitis C virus infection, antibiotics and obesity, a mitochondria killer mix?

Côté HC, Brumme ZL, Chan JW, Guillemi S, Montaner JS, Harrigan PR.

AIDS. 2006 Jun 12;20(9):1343-5. No abstract available.

PMID:
16816571
49.

Exploring mitochondrial nephrotoxicity as a potential mechanism of kidney dysfunction among HIV-infected patients on highly active antiretroviral therapy.

Côté HC, Magil AB, Harris M, Scarth BJ, Gadawski I, Wang N, Yu E, Yip B, Zalunardo N, Werb R, Hogg R, Harrigan PR, Montaner JS.

Antivir Ther. 2006;11(1):79-86.

PMID:
16518963
50.

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