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Items: 1 to 50 of 56

1.

Macroecological patterns of the phytoplankton production of polyunsaturated aldehydes.

Cózar A, Morillo-García S, Ortega MJ, Li QP, Bartual A.

Sci Rep. 2018 Aug 16;8(1):12282. doi: 10.1038/s41598-018-29787-8.

2.

Cooperative Catalysis with Coupled Chiral Induction in 1,3-Dipolar Cycloadditions of Azomethine Ylides.

Cayuelas A, Larrañaga O, Selva V, Nájera C, Akiyama T, Sansano JM, de Cózar A, Miranda JI, Cossío FP.

Chemistry. 2018 Jun 7;24(32):8092-8097. doi: 10.1002/chem.201801433. Epub 2018 May 15.

PMID:
29600546
3.

Characterization of microplastic litter from oceans by an innovative approach based on hyperspectral imaging.

Serranti S, Palmieri R, Bonifazi G, Cózar A.

Waste Manag. 2018 Jun;76:117-125. doi: 10.1016/j.wasman.2018.03.003. Epub 2018 Mar 5.

PMID:
29519600
4.

Ion-Pair SN 2 Reaction of OH- and CH3 Cl: Activation Strain Analyses of Counterion and Solvent Effects.

Laloo JZA, Rhyman L, Larrañaga O, Ramasami P, Bickelhaupt FM, de Cózar A.

Chem Asian J. 2018 May 4;13(9):1138-1147. doi: 10.1002/asia.201800082. Epub 2018 Apr 6.

PMID:
29437289
5.

Large-scale ocean connectivity and planktonic body size.

Villarino E, Watson JR, Jönsson B, Gasol JM, Salazar G, Acinas SG, Estrada M, Massana R, Logares R, Giner CR, Pernice MC, Olivar MP, Citores L, Corell J, Rodríguez-Ezpeleta N, Acuña JL, Molina-Ramírez A, González-Gordillo JI, Cózar A, Martí E, Cuesta JA, Agustí S, Fraile-Nuez E, Duarte CM, Irigoien X, Chust G.

Nat Commun. 2018 Jan 10;9(1):142. doi: 10.1038/s41467-017-02535-8.

6.

Catalysis of a 1,3-dipolar reaction by distorted DNA incorporating a heterobimetallic platinum(ii) and copper(ii) complex.

Rivilla I, de Cózar A, Schäfer T, Hernandez FJ, Bittner AM, Eleta-Lopez A, Aboudzadeh A, Santos JI, Miranda JI, Cossío FP.

Chem Sci. 2017 Oct 1;8(10):7038-7046. doi: 10.1039/c7sc02311a. Epub 2017 Aug 22.

7.

A Three-Component Enantioselective Cyclization Reaction Catalyzed by an Unnatural Amino Acid Derivative.

de Gracia Retamosa M, Ruiz-Olalla A, Bello T, de Cózar A, Cossío FP.

Angew Chem Int Ed Engl. 2018 Jan 15;57(3):668-672. doi: 10.1002/anie.201708952. Epub 2017 Dec 12.

PMID:
29120526
8.

Mono- and Di-Alkylation Processes of DNA Bases by Nitrogen Mustard Mechlorethamine.

Larrañaga O, de Cózar A, Cossío FP.

Chemphyschem. 2017 Dec 6;18(23):3390-3401. doi: 10.1002/cphc.201700937. Epub 2017 Oct 27.

PMID:
28981213
9.

Intramolecular SE Ar Reactions of Phosphorus Compounds: Computational Approach to the Synthesis of π-Extended Heterocycles.

Larrañaga O, Romero-Nieto C, de Cózar A.

Chemistry. 2017 Dec 11;23(69):17487-17496. doi: 10.1002/chem.201703495. Epub 2017 Nov 22.

PMID:
28922496
10.

A Guide for the Design of Functional Polyaromatic Organophosphorus Materials.

Hindenberg P, López-Andarias A, Rominger F, de Cózar A, Romero-Nieto C.

Chemistry. 2017 Oct 9;23(56):13919-13928. doi: 10.1002/chem.201701649. Epub 2017 Jul 27.

PMID:
28568909
11.

Diastereoselective [3 + 2] vs [4 + 2] Cycloadditions of Nitroprolinates with α,β-Unsaturated Aldehydes and Electrophilic Alkenes: An Example of Total Periselectivity.

Selva V, Larrañaga O, Castelló LM, Nájera C, Sansano JM, de Cózar A.

J Org Chem. 2017 Jun 16;82(12):6298-6312. doi: 10.1021/acs.joc.7b00903. Epub 2017 Jun 7.

PMID:
28534638
12.

The Arctic Ocean as a dead end for floating plastics in the North Atlantic branch of the Thermohaline Circulation.

Cózar A, Martí E, Duarte CM, García-de-Lomas J, van Sebille E, Ballatore TJ, Eguíluz VM, González-Gordillo JI, Pedrotti ML, Echevarría F, Troublè R, Irigoien X.

Sci Adv. 2017 Apr 19;3(4):e1600582. doi: 10.1126/sciadv.1600582. eCollection 2017 Apr.

13.

Alkenyl Arenes as Dipolarophiles in Catalytic Asymmetric 1,3-Dipolar Cycloaddition Reactions of Azomethine Ylides.

Pascual-Escudero A, de Cózar A, Cossío FP, Adrio J, Carretero JC.

Angew Chem Int Ed Engl. 2016 Dec 5;55(49):15334-15338. doi: 10.1002/anie.201609187. Epub 2016 Nov 11.

PMID:
27862800
14.

Donor-Stabilized 1,3-Disila-2,4-diazacyclobutadiene with a Nonbonded Si⋅⋅⋅Si Distance Compressed to a Si=Si Double Bond Length.

Gau D, Nougué R, Saffon-Merceron N, Baceiredo A, De Cózar A, Cossío FP, Hashizume D, Kato T.

Angew Chem Int Ed Engl. 2016 Nov 14;55(47):14673-14677. doi: 10.1002/anie.201608416. Epub 2016 Oct 20.

PMID:
27763730
15.

New Insights into the Reactivity of Cisplatin with Free and Restrained Nucleophiles: Microsolvation Effects and Base Selectivity in Cisplatin-DNA Interactions.

de Cózar A, Larrañaga O, Bickelhaupt FM, San Sebastián E, Ortega-Carrasco E, Maréchal JD, Lledós A, Cossío FP.

Chemphyschem. 2016 Dec 5;17(23):3932-3947. doi: 10.1002/cphc.201600982. Epub 2016 Oct 5.

PMID:
27642713
16.

Changes in the Floating Plastic Pollution of the Mediterranean Sea in Relation to the Distance to Land.

Pedrotti ML, Petit S, Elineau A, Bruzaud S, Crebassa JC, Dumontet B, Martí E, Gorsky G, Cózar A.

PLoS One. 2016 Aug 24;11(8):e0161581. doi: 10.1371/journal.pone.0161581. eCollection 2016.

17.

Risk Factors for Clostridium Difficile Diarrhea in Patients With Solid Organ Transplantation.

Ramos A, Ortiz J, Asensio Á, Martínez-Ruiz R, Múñez E, Cantero M, Cozar A, Ussetti P, Portolés J, Cuervas-Mons V.

Prog Transplant. 2016 Sep;26(3):231-7. doi: 10.1177/1526924816655073. Epub 2016 Jun 28.

PMID:
27358344
18.

Enantioselective Synthesis of Polysubstituted Spiro-nitroprolinates Mediated by a (R,R)-Me-DuPhos·AgF-Catalyzed 1,3-Dipolar Cycloaddition.

Cayuelas A, Ortiz R, Nájera C, Sansano JM, Larrañaga O, de Cózar A, Cossío FP.

Org Lett. 2016 Jun 17;18(12):2926-9. doi: 10.1021/acs.orglett.6b01273. Epub 2016 Jun 8.

PMID:
27268161
19.

Ion-Pair SN 2 Substitution: Activation Strain Analyses of Counter-Ion and Solvent Effects.

Laloo JZ, Rhyman L, Ramasami P, Bickelhaupt FM, de Cózar A.

Chemistry. 2016 Mar 18;22(13):4431-9. doi: 10.1002/chem.201504456. Epub 2016 Feb 16.

PMID:
26879231
20.

Synthesis of radiolabelled aryl azides from diazonium salts: experimental and computational results permit the identification of the preferred mechanism.

Joshi SM, de Cózar A, Gómez-Vallejo V, Koziorowski J, Llop J, Cossío FP.

Chem Commun (Camb). 2015 May 28;51(43):8954-7. doi: 10.1039/c5cc01913c.

21.

Plastic accumulation in the Mediterranean sea.

Cózar A, Sanz-Martín M, Martí E, González-Gordillo JI, Ubeda B, Gálvez JÁ, Irigoien X, Duarte CM.

PLoS One. 2015 Apr 1;10(4):e0121762. doi: 10.1371/journal.pone.0121762. eCollection 2015.

22.

Is it possible to achieve a complete desaturation of cycloalkanes promoted by o-benzyne?

Cervantes-Navarro F, de Cózar A, Cossío FP, Fernández-Herrera MA, Merino G, Fernández I.

Chem Commun (Camb). 2015 Mar 28;51(25):5302-5. doi: 10.1039/c4cc07311h.

PMID:
25360459
23.

Azobenzene-functionalized iridium(III) triscyclometalated complexes.

Pérez-Miqueo J, Telleria A, Muñoz-Olasagasti M, Altube A, García-Lecina E, de Cózar A, Freixa Z.

Dalton Trans. 2015 Feb 7;44(5):2075-91. doi: 10.1039/c4dt02018a.

PMID:
25188328
24.

Plastic debris in the open ocean.

Cózar A, Echevarría F, González-Gordillo JI, Irigoien X, Ubeda B, Hernández-León S, Palma AT, Navarro S, García-de-Lomas J, Ruiz A, Fernández-de-Puelles ML, Duarte CM.

Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10239-44. doi: 10.1073/pnas.1314705111. Epub 2014 Jun 30.

25.

Decadal trends and common dynamics of the bio-optical and thermal characteristics of the African Great Lakes.

Loiselle S, Cózar A, Adgo E, Ballatore T, Chavula G, Descy JP, Harper DM, Kansiime F, Kimirei I, Langenberg V, Ma R, Sarmento H, Odada E.

PLoS One. 2014 Apr 3;9(4):e93656. doi: 10.1371/journal.pone.0093656. eCollection 2014.

26.

Potential polyunsaturated aldehydes in the Strait of Gibraltar under two tidal regimes.

Morillo-García S, Valcárcel-Pérez N, Cózar A, Ortega MJ, Macías D, Ramírez-Romero E, García CM, Echevarría F, Bartual A.

Mar Drugs. 2014 Mar 13;12(3):1438-59. doi: 10.3390/md12031438.

27.

Polyunsaturated aldehydes from large phytoplankton of the Atlantic Ocean surface (42°n to 33°s).

Bartual A, Arandia-Gorostidi N, Cózar A, Morillo-García S, Ortega MJ, Vidal M, Cabello AM, González-Gordillo JI, Echevarría F.

Mar Drugs. 2014 Jan 27;12(2):682-99. doi: 10.3390/md12020682.

28.

Synthetic scope and DFT analysis of the chiral binap-gold(I) complex-catalyzed 1,3-dipolar cycloaddition of azlactones with alkenes.

Martín-Rodríguez M, Castelló LM, Nájera C, Sansano JM, Larrañaga O, de Cózar A, Cossío FP.

Beilstein J Org Chem. 2013 Nov 11;9:2422-33. doi: 10.3762/bjoc.9.280. eCollection 2013.

29.

Stereodivergent synthesis of chiral fullerenes by [3 + 2] cycloadditions to C₆₀.

Maroto EE, Filippone S, Suárez M, Martínez-Álvarez R, de Cózar A, Cossío FP, Martín N.

J Am Chem Soc. 2014 Jan 15;136(2):705-12. doi: 10.1021/ja410408c. Epub 2014 Jan 3.

30.

Aggregation and cooperative effects in the aldol reactions of lithium enolates.

Larrañaga O, de Cózar A, Bickelhaupt FM, Zangi R, Cossío FP.

Chemistry. 2013 Oct 4;19(41):13761-73. doi: 10.1002/chem.201301597. Epub 2013 Aug 21.

PMID:
23964002
31.

Potential effects of climate change on the water level, flora and macro-fauna of a large neotropical wetland.

Úbeda B, Di Giacomo AS, Neiff JJ, Loiselle SA, Poi AS, Gálvez JÁ, Casco S, Cózar A.

PLoS One. 2013 Jul 9;8(7):e67787. doi: 10.1371/journal.pone.0067787. Print 2013.

32.

Phosphoramidite-Cu(OTf)2 complexes as chiral catalysts for 1,3-dipolar cycloaddition of iminoesters and nitroalkenes.

Castelló LM, Nájera C, Sansano JM, Larrañaga O, de Cózar A, Cossío FP.

Org Lett. 2013 Jun 21;15(12):2902-5. doi: 10.1021/ol4006618. Epub 2013 Jun 11.

PMID:
23755738
33.

Stereodivergent SN2@P reactions of borane oxazaphospholidines: experimental and theoretical studies.

Zijlstra H, León T, de Cózar A, Fonseca Guerra C, Byrom D, Riera A, Verdaguer X, Bickelhaupt FM.

J Am Chem Soc. 2013 Mar 20;135(11):4483-91. doi: 10.1021/ja400208t. Epub 2013 Mar 7.

PMID:
23437771
34.

Chemical and sensory quality of lamb meat burgers from Manchego Spanish breed.

Linares MB, Cózar A, Garrido MD, Vergara H.

Int J Food Sci Nutr. 2012 Nov;63(7):843-52. doi: 10.3109/09637486.2012.681630. Epub 2012 Apr 24.

PMID:
22524617
35.

An amine-catalyzed enantioselective [3+2] cycloaddition of azomethine ylides and α,β-unsaturated aldehydes: applications and mechanistic implications.

Reboredo S, Reyes E, Vicario JL, Badía D, Carrillo L, de Cózar A, Cossío FP.

Chemistry. 2012 Jun 4;18(23):7179-88. doi: 10.1002/chem.201103015. Epub 2012 Apr 18.

PMID:
22511528
36.

Basin-scale control on the phytoplankton biomass in Lake Victoria, Africa.

Cózar A, Bruno M, Bergamino N, Ubeda B, Bracchini L, Dattilo AM, Loiselle SA.

PLoS One. 2012;7(1):e29962. doi: 10.1371/journal.pone.0029962. Epub 2012 Jan 9.

37.

Binap-gold(I) versus Binap-silver trifluoroacetate complexes as catalysts in 1,3-dipolar cycloadditions of azomethine ylides.

Martín-Rodríguez M, Nájera C, Sansano JM, de Cózar A, Cossío FP.

Chemistry. 2011 Dec 9;17(50):14224-33. doi: 10.1002/chem.201101606. Epub 2011 Nov 8.

PMID:
22069224
38.

Reversible binding of ethylene to silylene-phosphine complexes at room temperature.

Rodriguez R, Gau D, Kato T, Saffon-Merceron N, De Cózar A, Cossío FP, Baceiredo A.

Angew Chem Int Ed Engl. 2011 Oct 24;50(44):10414-6. doi: 10.1002/anie.201105097. Epub 2011 Sep 14. No abstract available.

PMID:
21915982
39.

Chiral gold(I) vs chiral silver complexes as catalysts for the enantioselective synthesis of the second generation GSK-hepatitis C virus inhibitor.

Martín-Rodríguez M, Nájera C, Sansano JM, de Cózar A, Cossío FP.

Beilstein J Org Chem. 2011;7:988-96. doi: 10.3762/bjoc.7.111. Epub 2011 Jul 19.

40.

Synthesis and reactivity of a phosphine-stabilized monogermanium analogue of alkynes.

Berthe J, Garcia JM, Ocando E, Kato T, Saffon-Merceron N, De Cózar A, Cossío FP, Baceiredo A.

J Am Chem Soc. 2011 Oct 12;133(40):15930-3. doi: 10.1021/ja2073577. Epub 2011 Sep 20.

PMID:
21913709
41.

Stereocontrolled (3+2) cycloadditions between azomethine ylides and dipolarophiles: a fruitful interplay between theory and experiment.

de Cózar A, Cossío FP.

Phys Chem Chem Phys. 2011 Jun 21;13(23):10858-68. doi: 10.1039/c1cp20682f. Epub 2011 May 13.

PMID:
21573305
42.

Hierarchical selectivity in fullerenes: site-, regio-, diastereo-, and enantiocontrol of the 1,3-dipolar cycloaddition to C70.

Maroto EE, de Cózar A, Filippone S, Martín-Domenech A, Suarez M, Cossío FP, Martín N.

Angew Chem Int Ed Engl. 2011 Jun 27;50(27):6060-4. doi: 10.1002/anie.201101246. Epub 2011 May 9. No abstract available.

PMID:
21557425
43.

Synthesis and characterization of metallodendritic palladium-biscarbene complexes derived from 1,1'-methylenebis(1,2,4-triazole).

Hornillos V, Guerra J, de Cózar A, Prieto P, Merino S, Maestro MA, Díez-Barra E, Tejeda J.

Dalton Trans. 2011 Apr 28;40(16):4095-103. doi: 10.1039/c0dt01535k. Epub 2011 Mar 7.

PMID:
21384005
44.

Synthesis of a stable disilyne bisphosphine adduct and its non-metal-mediated CO2 reduction to CO.

Gau D, Rodriguez R, Kato T, Saffon-Merceron N, de Cózar A, Cossío FP, Baceiredo A.

Angew Chem Int Ed Engl. 2011 Feb 1;50(5):1092-6. doi: 10.1002/anie.201006265. Epub 2010 Dec 22. No abstract available.

PMID:
21268202
45.

Influence of polarity on the scalability and reproducibility of solvent-free microwave-assisted reactions.

Díaz-Ortiz A, de la Hoz A, Alcázar J, Carrillo JR, Herrero MA, Fontana A, Muñoz Jde M, Prieto P, de Cózar A.

Comb Chem High Throughput Screen. 2011 Feb;14(2):109-16.

PMID:
21143180
46.

Assessing the optical changes in dissolved organic matter in humic lakes by spectral slope distributions.

Galgani L, Tognazzi A, Rossi C, Ricci M, Galvez JA, Dattilo AM, Cozar A, Bracchini L, Loiselle SA.

J Photochem Photobiol B. 2011 Feb 7;102(2):132-9. doi: 10.1016/j.jphotobiol.2010.10.001. Epub 2010 Oct 23.

PMID:
21078559
47.

A cationic Rh(III) complex that efficiently catalyzes hydrogen isotope exchange in hydrosilanes.

Campos J, Esqueda AC, López-Serrano J, Sánchez L, Cossio FP, de Cozar A, Alvarez E, Maya C, Carmona E.

J Am Chem Soc. 2010 Dec 1;132(47):16765-7. doi: 10.1021/ja108521b. Epub 2010 Nov 9.

PMID:
21062088
48.

Concerted and stepwise mechanisms in metal-free and metal-assisted [4+3] cycloadditions involving allyl cations.

Fernández I, Cossío FP, de Cózar A, Lledós A, Mascareñas JL.

Chemistry. 2010 Oct 25;16(40):12147-57. doi: 10.1002/chem.201001714.

PMID:
20839191
49.

Synthesis and structure of a base-stabilized C-phosphino-Si-amino silyne.

Gau D, Kato T, Saffon-Merceron N, De Cózar A, Cossío FP, Baceiredo A.

Angew Chem Int Ed Engl. 2010 Sep 3;49(37):6585-8. doi: 10.1002/anie.201003616. No abstract available.

PMID:
20677192
50.

Computational calculations in microwave-assisted organic synthesis (MAOS). Application to cycloaddition reactions.

de Cózar A, Millán MC, Cebrián C, Prieto P, Díaz-Ortiz A, de la Hoz A, Cossío FP.

Org Biomol Chem. 2010 Mar 7;8(5):1000-9. doi: 10.1039/b922730j. Epub 2010 Jan 15.

PMID:
20165789

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